Pharmacogenetics and Clinical Risk Factors for Risperidone- Related Weight Gain in Thai Autistic Spectrum Disorder Patients

Name: Work Video:
Duration: 3 min 30 s
Natchaya Vanwong; Sadeep Medhasi; Manat Pongchaidecha; Nattawat Ngamsamut; Apichaya Puangpetch; Montri Chamnanphon; Bhunnada Chamkrachchangpada; Teerarat Tan-kam; Yaowaluck Hongkaew; Penkhae Limsila; Chonlaphat Sukasem
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[38], 'obesity': [39], 'and': [40, 75, 95, 105, 151, 174, 201], 'several': [41], 'health': [42], 'problems.': [43], 'Objective': [46], ':': [49], 'To': [51], 'investigate': [52], 'factors': [54, 159], 'associated': [55], 'with': [56, 83], 'risperidone-related': [57], 'in': [60, 194, 209], 'Thai': [61, 79, 136, 211], 'autistic': [62, 80, 137], 'spectrum': [63], 'disorder': [64], 'patients.': [65, 212], 'Methods:': [68], 'We': [71], 'conducted': [72], 'retrospective': [74], 'observational': [76], 'study': [77, 183], 'among': [78, 134], 'treated': [82], 'risperidone.': [84], 'The': [85], 'data': [86], 'collected': [87], 'included': [88], 'risperidone': [89, 117, 142], 'dose,': [90], 'sex,': [91], 'age,': [92], 'body': [93, 113, 162], 'BMI': [96, 152], 'baseline,': [97], 'concomitant': [98], 'drug': [99, 103], 'therapy,': [100], 'duration': [101, 140, 166], 'used,': [104], 'phenotype/genotype': [106], 'CYP2D6': [109], 'responsible': [111], 'for': [112, 191, 206], 'during': [116], 'therapy.': [118], 'Results:': [121], 'Univariate\xa0': [124], 'analysis\xa0': [125], 'showed\xa0': [126], 'that\xa0': [127], 'factors\xa0': [128], 'affecting\xa0': [129], 'the\xa0': [130], 'body\xa0': [131], 'risperidone-treated': [135, 210], 'were\xa0': [139], 'treatment': [143, 168], '(months)': [144, 169], '(P<0.0001),': [145, 148], 'cumulative': [146], 'dose': [147], 'age': [149, 172, 175], '(P=0.001)': [150], 'baseline': [153, 171], '(P<0.01).': [154], 'Multivariable': [155], 'analysis': [156], 'showed': [157], 'that': [158], 'affecting': [160], 'were': [165], '(P=0.011),': [170], '(P=0.002)': [173], '(P<0.0001).': [176], 'Conclusions:': [179], 'This': [182], 'makes': [184], 'preliminary': [186], 'contribution': [187], 'provide': [189], 'opportunities': [190], 'personalized': [192], 'medicine': [193], 'predictive': [196], 'assessment': [197], 'minimize': [203], 'metabolic': [207], 'syndrome': [208]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1579919533', 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