Abstract: Quantitative computed tomography (QCT) is an established
technique for measuring bone mineral density (BMD) in the axial
spine and appendicular skeleton (forearm, tibia). It provides
cross-sectional images, so that it is uniquely able to provide
separate estimates of trabecular and cortical bone BMD as well
as a true volumetric mineral density in grams per cubic centimeter.
However, because of the high responsiveness of spinal trabecular
bone and its importance for vertebral strength, it has
been principally employed to determine trabecular BMD in the
vertebral body. QCT has been used for assessment of vertebral
fracture risk, measurement of age-related bone loss, and followup
of osteoporosis and other metabolic bone diseases. QCT has
a better sensitivity to predict vertebral fracture than projectional
methods like DXA, due to its ability to isolate and measure trabecular
bone in the center of vertebral body. This mini-review
deals with the current capabilities of axial QCT and the recent
technical developments, including volumetric acquisition
Publication Year: 2005
Publication Date: 2005-05-01
Language: en
Type: article
Access and Citation
Cited By Count: 3
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