Publication Information

{'id': 'https://openalex.org/W1491640607', 'doi': 'https://doi.org/10.18632/oncotarget.1586', 'title': 'Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer', 'display_name': 'Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer', 'publication_year': 2013, 'publication_date': '2013-11-23', 'ids': {'openalex': 'https://openalex.org/W1491640607', 'doi': 'https://doi.org/10.18632/oncotarget.1586', 'mag': '1491640607', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24353195', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3926840'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1586', 'pdf_url': 'https://www.oncotarget.com/article/1586/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.oncotarget.com/article/1586/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025203839', 'display_name': 'Luigi Fontana', 'orcid': 'https://orcid.org/0000-0001-8500-5537'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}, {'id': 'https://openalex.org/I131729948', 'display_name': 'University of Salerno', 'ror': 'https://ror.org/0192m2k53', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I131729948']}, {'id': 'https://openalex.org/I4210128854', 'display_name': 'Ceinge Biotecnologie Avanzate (Italy)', 'ror': 'https://ror.org/033pa2k60', 'country_code': 'IT', 'type': 'company', 'lineage': ['https://openalex.org/I4210128854']}], 'countries': ['IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Luigi Fontana', 'raw_affiliation_strings': ['CEINGE Biotecnologie Avanzate, Napoli, Italy', 'Department of Medicine, Salerno University Medical School, Salerno, Italy', 'Department of Medicine, Washington University in St. Louis, MO, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Washington University in St. Louis, MO, USA.', 'institution_ids': ['https://openalex.org/I204465549']}, {'raw_affiliation_string': 'Department of Medicine, Salerno University Medical School, Salerno, Italy', 'institution_ids': ['https://openalex.org/I131729948']}, {'raw_affiliation_string': 'CEINGE Biotecnologie Avanzate, Napoli, Italy', 'institution_ids': ['https://openalex.org/I4210128854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074499498', 'display_name': 'Remi Adelaiye‐Ogala', 'orcid': 'https://orcid.org/0000-0002-6581-7359'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Remi M. Adelaiye', 'raw_affiliation_strings': ['Department of Cancer Pathology and Prevention, Roswell Park Cancer Institute Division, University at Buffalo, NY', 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY', 'institution_ids': ['https://openalex.org/I1292894508']}, {'raw_affiliation_string': 'Department of Cancer Pathology and Prevention, Roswell Park Cancer Institute Division, University at Buffalo, NY', 'institution_ids': ['https://openalex.org/I1292894508']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029134027', 'display_name': 'Antonella Rastelli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Antonella L. Rastelli', 'raw_affiliation_strings': ['Department of Medicine, Washington University in St. Louis, MO, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Washington University in St. Louis, MO, USA', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072996841', 'display_name': 'Kiersten Marie Miles', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kiersten Marie Miles', 'raw_affiliation_strings': ['Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY', 'institution_ids': ['https://openalex.org/I1292894508']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087493522', 'display_name': 'Eric Ciamporcero', 'orcid': 'https://orcid.org/0000-0002-3856-6435'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}, {'id': 'https://openalex.org/I55143463', 'display_name': 'University of Turin', 'ror': 'https://ror.org/048tbm396', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I55143463']}], 'countries': ['IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Eric Ciamporcero', 'raw_affiliation_strings': ['Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY', 'Medicine and Experimental Oncology, University of Turin, Turin Italy'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY', 'institution_ids': ['https://openalex.org/I1292894508']}, {'raw_affiliation_string': 'Medicine and Experimental Oncology, University of Turin, Turin Italy', 'institution_ids': ['https://openalex.org/I55143463']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073120806', 'display_name': 'Valter D. Longo', 'orcid': 'https://orcid.org/0000-0002-0946-7534'}, 'institutions': [{'id': 'https://openalex.org/I1174212', 'display_name': 'University of Southern California', 'ror': 'https://ror.org/03taz7m60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1174212']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Valter D. Longo', 'raw_affiliation_strings': ['Longevity Institute School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Longevity Institute School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA', 'institution_ids': ['https://openalex.org/I1174212']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002466627', 'display_name': 'Holly M. Nguyen', 'orcid': 'https://orcid.org/0000-0002-6331-8089'}, 'institutions': [{'id': 'https://openalex.org/I2801852214', 'display_name': 'University of Washington Medical Center', 'ror': 'https://ror.org/00wbzw723', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801852214']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Holly Nguyen', 'raw_affiliation_strings': ['Department of Urology, University of Washington Medical Center, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urology, University of Washington Medical Center, USA', 'institution_ids': ['https://openalex.org/I2801852214']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108554327', 'display_name': 'Robert L. Vessella', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801852214', 'display_name': 'University of Washington Medical Center', 'ror': 'https://ror.org/00wbzw723', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801852214']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert Vessella', 'raw_affiliation_strings': ['Department of Urology, University of Washington Medical Center, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urology, University of Washington Medical Center, USA', 'institution_ids': ['https://openalex.org/I2801852214']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5003107448', 'display_name': 'Роберто Пили', 'orcid': 'https://orcid.org/0000-0002-5871-4896'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Roberto Pili', 'raw_affiliation_strings': ['Department of Cancer Pathology and Prevention, Roswell Park Cancer Institute Division, University at Buffalo, NY', 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Program, Roswell Park Cancer Institute, Buffalo NY', 'institution_ids': ['https://openalex.org/I1292894508']}, {'raw_affiliation_string': 'Department of Cancer Pathology and Prevention, Roswell Park Cancer Institute Division, University at Buffalo, NY', 'institution_ids': ['https://openalex.org/I1292894508']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.814, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 117, 'citation_normalized_percentile': {'value': 0.999954, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '4', 'issue': '12', 'first_page': '2451', 'last_page': '2461'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13984', 'display_name': 'Nutrition, Genetics, and Disease', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13984', 'display_name': 'Nutrition, Genetics, and Disease', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13199', 'display_name': 'Digestive system and related health', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12267', 'display_name': 'Diet and metabolism studies', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.7107581}, {'id': 'https://openalex.org/C86554907', 'wikidata': 'https://www.wikidata.org/wiki/Q285613', 'display_name': 'PI3K/AKT/mTOR pathway', 'level': 3, 'score': 0.58395445}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.5427961}, {'id': 'https://openalex.org/C2776235491', 'wikidata': 'https://www.wikidata.org/wiki/Q9625', 'display_name': 'Prostate', 'level': 3, 'score': 0.541344}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.53486}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.52987707}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.52515715}, {'id': 'https://openalex.org/C75217442', 'wikidata': 'https://www.wikidata.org/wiki/Q423650', 'display_name': 'Protein kinase B', 'level': 3, 'score': 0.50596374}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.48626387}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.47394612}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.44461212}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.41376883}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.32900214}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.22395283}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0657475}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000178', 'qualifier_name': 'diet therapy', 'is_major_topic': True}, {'descriptor_ui': 'D018753', 'descriptor_name': 'Diet, Protein-Restricted', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D004044', 'descriptor_name': 'Dietary Proteins', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000178', 'qualifier_name': 'diet therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048708', 'descriptor_name': 'Cell Growth Processes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048708', 'descriptor_name': 'Cell Growth Processes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018753', 'descriptor_name': 'Diet, Protein-Restricted', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004044', 'descriptor_name': 'Dietary Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007334', 'descriptor_name': 'Insulin-Like Growth Factor I', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007334', 'descriptor_name': 'Insulin-Like Growth Factor I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008813', 'descriptor_name': 'Mice, Inbred ICR', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016513', 'descriptor_name': 'Mice, SCID', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010940', 'descriptor_name': 'Plant Proteins', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D010940', 'descriptor_name': 'Plant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011897', 'descriptor_name': 'Random Allocation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023041', 'descriptor_name': 'Xenograft Model Antitumor Assays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1586', 'pdf_url': 'https://www.oncotarget.com/article/1586/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3926840', 'pdf_url': 'https://europepmc.org/articles/pmc3926840?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926840', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24353195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1586', 'pdf_url': 'https://www.oncotarget.com/article/1586/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.84, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 38, 'referenced_works': ['https://openalex.org/W149123109', 'https://openalex.org/W1839306363', 'https://openalex.org/W1875199757', 'https://openalex.org/W1970937302', 'https://openalex.org/W1974965213', 'https://openalex.org/W1981989535', 'https://openalex.org/W1986798894', 'https://openalex.org/W1987245317', 'https://openalex.org/W1989891233', 'https://openalex.org/W2003664417', 'https://openalex.org/W2004998430', 'https://openalex.org/W2020636054', 'https://openalex.org/W2031253131', 'https://openalex.org/W2035030519', 'https://openalex.org/W2044776722', 'https://openalex.org/W2044984438', 'https://openalex.org/W2050673328', 'https://openalex.org/W2053116646', 'https://openalex.org/W2056062536', 'https://openalex.org/W2057418848', 'https://openalex.org/W2057434992', 'https://openalex.org/W2059716825', 'https://openalex.org/W2065570670', 'https://openalex.org/W2075884509', 'https://openalex.org/W2098968025', 'https://openalex.org/W2115806147', 'https://openalex.org/W2119602224', 'https://openalex.org/W2120912740', 'https://openalex.org/W2123777965', 'https://openalex.org/W2126945850', 'https://openalex.org/W2128412799', 'https://openalex.org/W2137541551', 'https://openalex.org/W2139419463', 'https://openalex.org/W2165781101', 'https://openalex.org/W2413138283', 'https://openalex.org/W4242005208', 'https://openalex.org/W4285719527', 'https://openalex.org/W54928609'], 'related_works': ['https://openalex.org/W4312127270', 'https://openalex.org/W3006030203', 'https://openalex.org/W2974310060', 'https://openalex.org/W2948341381', 'https://openalex.org/W2912656088', 'https://openalex.org/W2438578109', 'https://openalex.org/W2389520000', 'https://openalex.org/W2145454786', 'https://openalex.org/W1988747615', 'https://openalex.org/W1980245127'], 'abstract_inverted_index': {'//': [0, 144, 148], 'Luigi': [1, 141], 'Fontana': [2], '1,2,3,*': [3], ',': [4, 9, 14, 19, 23, 28, 32, 36], 'Remi': [5], 'M.': [6], 'Adelaiye': [7], '4,5,*': [8], 'Antonella': [10], 'L.': [11], 'Rastelli': [12], '1': [13, 41], 'Kiersten': [15], 'Marie': [16], 'Miles': [17], '4': [18, 68], 'Eric': [20], 'Ciamporcero': [21], '4,6': [22], 'Valter': [24], 'D.': [25], 'Longo': [26], '7': [27, 103], 'Holly': [29], 'Nguyen': [30], '8': [31, 35, 122], 'Robert': [33], 'Vessella': [34], 'and': [37, 82, 95, 109, 155, 176, 191, 216, 236, 242, 247, 273, 310, 325, 339, 404, 416], 'Roberto': [38, 145], 'Pili': [39], '4,5': [40], 'Department': [42, 53, 78, 110, 123], 'of': [43, 54, 79, 99, 107, 111, 115, 124, 127, 206, 230, 263, 298, 314, 330, 351, 356, 412], 'Medicine,': [44, 55], 'Washington': [45, 128], 'University': [46, 57, 89, 98, 114, 126], 'in': [47, 188, 266, 277, 302, 327, 389, 396, 400], 'St.': [48], 'Louis,': [49], 'MO,': [50], 'USA;': [51, 121], '2': [52], 'Salerno': [56], 'Medical': [58, 129], 'School,': [59], 'Salerno,': [60], 'Italy;': [61, 67, 102], '3': [62], 'CEINGE': [63], 'Biotecnologie': [64], 'Avanzate,': [65], 'Napoli,': [66], 'Genitourinary': [69], 'Program,': [70], 'Roswell': [71, 84], 'Park': [72, 85], 'Cancer': [73, 80, 86], 'Institute,': [74], 'Buffalo': [75], 'NY;': [76, 92], '5': [77], 'Pathology': [81], 'Prevention,': [83], 'Institute': [87, 105], 'Division,': [88], 'at': [90], 'Buffalo,': [91], '6': [93], 'Medicine': [94], 'Experimental': [96, 219], 'Oncology,': [97], 'Turin,': [100], 'Turin': [101], 'Longevity': [104], 'School': [106], 'Gerontology': [108], 'Biological': [112], 'Sciences,': [113], 'Southern': [116], 'California,': [117], 'Los': [118], 'Angeles,': [119], 'CA,': [120], 'Urology,': [125], 'Center,': [130], 'USA': [131], '*': [132], 'These': [133], 'authors': [134], 'contributed': [135], 'equally': [136], 'to': [137, 291, 375], 'this': [138, 200], 'research': [139], 'Correspondence:': [140], 'Fontana,': [142], 'email:': [143, 147], 'Pili,': [146], 'Keywords': [149], ':': [150, 159], 'protein': [151, 182, 210, 231, 287, 295, 353, 357, 367, 380, 391], 'restriction,': [152], 'mTOR,': [153], 'prostate': [154, 190, 215, 235, 270, 331, 403], 'breast': [156, 192, 217, 237, 280, 405], 'cancer': [157, 193, 238, 254, 271, 281, 332, 406], 'Received': [158], 'November': [160, 164, 168], '8,': [161], '2013': [162, 166, 170], 'Accepted:': [163], '21,': [165], 'Published:': [167], '23,': [169], 'Abstract': [171], 'Purpose:': [172], 'Data': [173], 'from': [174], 'epidemiological': [175], 'experimental': [177], 'studies': [178], 'suggest': [179, 385], 'that': [180, 349, 386], 'dietary': [181, 352, 390], 'intake': [183, 392], 'may': [184], 'play': [185], 'a': [186, 260, 274, 285, 376, 387], 'role': [187], 'inhibiting': [189, 397], 'by': [194, 250, 322, 371], 'modulating': [195], 'the': [196, 204, 227, 267, 278, 303, 335, 340, 410, 413], 'IGF/AKT/mTOR': [197, 414], 'pathway.': [198], 'In': [199, 345], 'study': [201], 'we': [202, 225, 347], 'investigated': [203], 'effects': [205], 'diets': [207], 'with': [208, 284, 306], 'different': [209], 'content': [211], 'or': [212], 'quality': [213], 'on': [214, 234], 'cancer.': [218], 'Design:': [220], 'To': [221], 'test': [222], 'our': [223], 'hypothesis': [224], 'assessed': [226], 'inhibitory': [228], 'effect': [229], 'diet': [232, 288, 363], 'restriction': [233], 'growth,': [239], 'serum': [240, 308], 'PSA': [241, 309], 'IGF-1': [243, 311], 'concentrations,': [244], 'mTOR': [245], 'activity': [246], 'epigenetic': [248, 328, 417], 'markers,': [249], 'using': [251], 'human': [252, 401], 'xenograft': [253, 402], 'models.': [255], 'Results:': [256], 'Our': [257, 383], 'results': [258], 'showed': [259], '70%': [261], 'inhibition': [262, 276, 411], 'tumor': [264, 299, 360, 369, 398], 'growth': [265, 300, 399], 'castrate-resistant': [268], 'LuCaP23.1': [269, 304], 'model': [272, 282], '56%': [275], 'WHIM16': [279], 'fed': [283], '7%': [286], 'when': [289], 'compared': [290, 374], 'an': [292], 'isocaloric': [293], '21%': [294], 'diet.': [296, 381], 'Inhibition': [297], 'correlated,': [301], 'model,': [305], 'decreased': [307, 317, 359], 'levels,': [312], 'down-regulation': [313], 'mTORC1': [315], 'activity,': [316], 'cell': [318], 'proliferation': [319], 'as': [320, 373], 'indicated': [321], 'Ki67': [323], 'staining,': [324], 'reduction': [326, 388], 'markers': [329], 'progression,': [333], 'including': [334], 'histone': [336, 342], 'methyltransferase': [337], 'EZH2': [338], 'associated': [341], 'mark': [343], 'H3K27me3.': [344], 'addition,': [346], 'observed': [348], 'modifications': [350], 'quality,': [354], 'independently': [355], 'quantity,': [358], 'growth.': [361], 'A': [362], 'containing': [364], '20%': [365, 377], 'plant': [366], 'inhibited': [368], 'weight': [370], '37%': [372], 'animal': [378], 'dairy': [379], 'Conclusions:': [382], 'findings': [384], 'is': [393], 'highly': [394], 'effective': [395], 'models,': [407], 'possibly': [408], 'through': [409], 'pathway': [415], 'modifications.': [418]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1491640607', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-09T11:34:55.322046', 'created_date': '2016-06-24'}