Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1485657158', 'doi': 'https://doi.org/10.3389/fmicb.2015.00672', 'title': 'Biotechnological applications of functional metagenomics in the food and pharmaceutical industries', 'display_name': 'Biotechnological applications of functional metagenomics in the food and pharmaceutical industries', 'publication_year': 2015, 'publication_date': '2015-06-30', 'ids': {'openalex': 'https://openalex.org/W1485657158', 'doi': 'https://doi.org/10.3389/fmicb.2015.00672', 'mag': '1485657158', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26175729', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4485178'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmicb.2015.00672', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmicb.2015.00672/pdf', 'source': {'id': 'https://openalex.org/S2484704948', 'display_name': 'Frontiers in Microbiology', 'issn_l': '1664-302X', 'issn': ['1664-302X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fmicb.2015.00672/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067827407', 'display_name': 'Laura M. Coughlan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141766778', 'display_name': 'Teagasc - The Irish Agriculture and Food Development Authority', 'ror': 'https://ror.org/03sx84n71', 'country_code': 'IE', 'type': 'facility', 'lineage': ['https://openalex.org/I141766778']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Laura M. Coughlan', 'raw_affiliation_strings': ['Teagasc Food Research Centre, Cork, Ireland'], 'affiliations': [{'raw_affiliation_string': 'Teagasc Food Research Centre, Cork, Ireland', 'institution_ids': ['https://openalex.org/I141766778']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050465932', 'display_name': 'Paul D. Cotter', 'orcid': 'https://orcid.org/0000-0002-5465-9068'}, 'institutions': [{'id': 'https://openalex.org/I4210142287', 'display_name': 'Alimentary Health (Ireland)', 'ror': 'https://ror.org/05a5s1z53', 'country_code': 'IE', 'type': 'company', 'lineage': ['https://openalex.org/I4210142287']}, {'id': 'https://openalex.org/I141766778', 'display_name': 'Teagasc - The Irish Agriculture and Food Development Authority', 'ror': 'https://ror.org/03sx84n71', 'country_code': 'IE', 'type': 'facility', 'lineage': ['https://openalex.org/I141766778']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Paul D. Cotter', 'raw_affiliation_strings': ['Alimentary Pharmabiotic Centre, Cork, Ireland', 'Teagasc Food Research Centre, Cork, Ireland'], 'affiliations': [{'raw_affiliation_string': 'Alimentary Pharmabiotic Centre, Cork, Ireland', 'institution_ids': ['https://openalex.org/I4210142287']}, {'raw_affiliation_string': 'Teagasc Food Research Centre, Cork, Ireland', 'institution_ids': ['https://openalex.org/I141766778']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047441756', 'display_name': 'Colin Hill', 'orcid': 'https://orcid.org/0000-0002-8527-1445'}, 'institutions': [{'id': 'https://openalex.org/I27577105', 'display_name': 'University College Cork', 'ror': 'https://ror.org/03265fv13', 'country_code': 'IE', 'type': 'education', 'lineage': ['https://openalex.org/I27577105']}, {'id': 'https://openalex.org/I4210142287', 'display_name': 'Alimentary Health (Ireland)', 'ror': 'https://ror.org/05a5s1z53', 'country_code': 'IE', 'type': 'company', 'lineage': ['https://openalex.org/I4210142287']}], 'countries': ['IE'], 'is_corresponding': False, 'raw_author_name': 'Colin Hill', 'raw_affiliation_strings': ['Alimentary Pharmabiotic Centre, Cork, Ireland', 'School of Microbiology, University College Cork, Cork, Ireland'], 'affiliations': [{'raw_affiliation_string': 'School of Microbiology, University College Cork, Cork, Ireland', 'institution_ids': ['https://openalex.org/I27577105']}, {'raw_affiliation_string': 'Alimentary Pharmabiotic Centre, Cork, Ireland', 'institution_ids': ['https://openalex.org/I4210142287']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047897845', 'display_name': 'Avelino Álvarez‐Ordóñez', 'orcid': 'https://orcid.org/0000-0002-9951-4786'}, 'institutions': [{'id': 'https://openalex.org/I141766778', 'display_name': 'Teagasc - The Irish Agriculture and Food Development Authority', 'ror': 'https://ror.org/03sx84n71', 'country_code': 'IE', 'type': 'facility', 'lineage': ['https://openalex.org/I141766778']}], 'countries': ['IE'], 'is_corresponding': True, 'raw_author_name': 'Avelino Alvarez-Ordóñez', 'raw_affiliation_strings': ['Teagasc Food Research Centre, Cork, Ireland'], 'affiliations': [{'raw_affiliation_string': 'Teagasc Food Research Centre, Cork, Ireland', 'institution_ids': ['https://openalex.org/I141766778']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5047897845'], 'corresponding_institution_ids': ['https://openalex.org/I141766778'], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 1.819, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 111, 'citation_normalized_percentile': {'value': 0.995842, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '6', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10141', 'display_name': 'Probiotics and Fermented Foods', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10141', 'display_name': 'Probiotics and Fermented Foods', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10015', 'display_name': 'Genomics and Phylogenetic Studies', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10252', 'display_name': 'Microbial Natural Products and Biosynthesis', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/identification', 'display_name': 'Identification', 'score': 0.48995653}], 'concepts': [{'id': 'https://openalex.org/C15151743', 'wikidata': 'https://www.wikidata.org/wiki/Q903778', 'display_name': 'Metagenomics', 'level': 3, 'score': 0.95769525}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.5413871}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.5131636}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.50633943}, {'id': 'https://openalex.org/C116834253', 'wikidata': 'https://www.wikidata.org/wiki/Q2039217', 'display_name': 'Identification (biology)', 'level': 2, 'score': 0.48995653}, {'id': 'https://openalex.org/C183696295', 'wikidata': 'https://www.wikidata.org/wiki/Q2487696', 'display_name': 'Biochemical engineering', 'level': 1, 'score': 0.45859683}, {'id': 'https://openalex.org/C74187038', 'wikidata': 'https://www.wikidata.org/wiki/Q1418791', 'display_name': 'Drug discovery', 'level': 2, 'score': 0.43007654}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.20663548}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.20546243}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.18396497}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.15279752}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.12543172}], 'mesh': [], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmicb.2015.00672', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmicb.2015.00672/pdf', 'source': {'id': 'https://openalex.org/S2484704948', 'display_name': 'Frontiers in Microbiology', 'issn_l': '1664-302X', 'issn': ['1664-302X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/261ff48a621847968fcad40438fb63b2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4485178', 'pdf_url': 'https://europepmc.org/articles/pmc4485178?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/11019/1059', 'pdf_url': 'https://t-stor.teagasc.ie/bitstream/11019/1059/1/fmicb-06-00672.pdf', 'source': {'id': 'https://openalex.org/S4306402356', 'display_name': 'T-Stór (Teagasc)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I141766778', 'host_organization_name': 'Teagasc - The Irish Agriculture and Food Development Authority', 'host_organization_lineage': ['https://openalex.org/I141766778'], 'host_organization_lineage_names': ['Teagasc - The Irish Agriculture and Food Development Authority'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485178', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26175729', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmicb.2015.00672', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmicb.2015.00672/pdf', 'source': {'id': 'https://openalex.org/S2484704948', 'display_name': 'Frontiers in Microbiology', 'issn_l': '1664-302X', 'issn': ['1664-302X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Responsible consumption and production', 'id': 'https://metadata.un.org/sdg/12', 'score': 0.53}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 147, 'referenced_works': ['https://openalex.org/W1506863959', 'https://openalex.org/W1545201063', 'https://openalex.org/W1802749802', 'https://openalex.org/W1873385545', 'https://openalex.org/W1893993890', 'https://openalex.org/W1907872891', 'https://openalex.org/W1910109602', 'https://openalex.org/W1941446924', 'https://openalex.org/W1957158838', 'https://openalex.org/W1964106002', 'https://openalex.org/W1964380002', 'https://openalex.org/W1965574259', 'https://openalex.org/W1968274808', 'https://openalex.org/W1969346416', 'https://openalex.org/W1970798262', 'https://openalex.org/W1975282222', 'https://openalex.org/W1977163133', 'https://openalex.org/W1978737414', 'https://openalex.org/W1980592886', 'https://openalex.org/W1980888168', 'https://openalex.org/W1984201842', 'https://openalex.org/W1985373276', 'https://openalex.org/W1985744610', 'https://openalex.org/W1986189475', 'https://openalex.org/W1986514482', 'https://openalex.org/W1987626087', 'https://openalex.org/W1991546528', 'https://openalex.org/W1993024390', 'https://openalex.org/W1993645434', 'https://openalex.org/W1994863517', 'https://openalex.org/W2003578114', 'https://openalex.org/W2004690636', 'https://openalex.org/W2004960255', 'https://openalex.org/W2005884670', 'https://openalex.org/W2009046676', 'https://openalex.org/W2009659777', 'https://openalex.org/W2010751274', 'https://openalex.org/W2011084061', 'https://openalex.org/W2012251902', 'https://openalex.org/W2012551538', 'https://openalex.org/W2012775161', 'https://openalex.org/W2015982724', 'https://openalex.org/W2016523761', 'https://openalex.org/W2017364432', 'https://openalex.org/W2017739927', 'https://openalex.org/W2018035315', 'https://openalex.org/W2018626507', 'https://openalex.org/W2021604437', 'https://openalex.org/W2021722888', 'https://openalex.org/W2024834197', 'https://openalex.org/W2025295902', 'https://openalex.org/W2033002674', 'https://openalex.org/W2037270005', 'https://openalex.org/W2037988297', 'https://openalex.org/W2039393915', 'https://openalex.org/W2041724627', 'https://openalex.org/W2042404916', 'https://openalex.org/W2046703733', 'https://openalex.org/W2046889034', 'https://openalex.org/W2049347668', 'https://openalex.org/W2051534836', 'https://openalex.org/W2052939914', 'https://openalex.org/W2053459584', 'https://openalex.org/W2059112462', 'https://openalex.org/W2059693783', 'https://openalex.org/W2059880645', 'https://openalex.org/W2061750017', 'https://openalex.org/W2063756270', 'https://openalex.org/W2064073012', 'https://openalex.org/W2065572297', 'https://openalex.org/W2066784459', 'https://openalex.org/W2067288447', 'https://openalex.org/W2069516907', 'https://openalex.org/W2069616003', 'https://openalex.org/W2070870981', 'https://openalex.org/W2072812562', 'https://openalex.org/W2074862047', 'https://openalex.org/W2076184415', 'https://openalex.org/W2077471750', 'https://openalex.org/W2082949742', 'https://openalex.org/W2083893895', 'https://openalex.org/W2086589133', 'https://openalex.org/W2086903819', 'https://openalex.org/W2088115879', 'https://openalex.org/W2090199399', 'https://openalex.org/W2090797929', 'https://openalex.org/W2091564674', 'https://openalex.org/W2093389098', 'https://openalex.org/W2094544330', 'https://openalex.org/W2094678636', 'https://openalex.org/W2095577293', 'https://openalex.org/W2097127377', 'https://openalex.org/W2098949773', 'https://openalex.org/W2099297431', 'https://openalex.org/W2103938843', 'https://openalex.org/W2109509948', 'https://openalex.org/W2110300022', 'https://openalex.org/W2110375946', 'https://openalex.org/W2111537738', 'https://openalex.org/W2113601822', 'https://openalex.org/W2113739824', 'https://openalex.org/W2115476058', 'https://openalex.org/W2116138044', 'https://openalex.org/W2118401092', 'https://openalex.org/W2124010228', 'https://openalex.org/W2124172509', 'https://openalex.org/W2127134779', 'https://openalex.org/W2129212653', 'https://openalex.org/W2132911648', 'https://openalex.org/W2133502054', 'https://openalex.org/W2134491693', 'https://openalex.org/W2135755676', 'https://openalex.org/W2140477768', 'https://openalex.org/W2141368045', 'https://openalex.org/W2141929300', 'https://openalex.org/W2144318297', 'https://openalex.org/W2145985839', 'https://openalex.org/W2146593660', 'https://openalex.org/W2147103640', 'https://openalex.org/W2148903381', 'https://openalex.org/W2150552080', 'https://openalex.org/W2151240736', 'https://openalex.org/W2152620329', 'https://openalex.org/W2155448001', 'https://openalex.org/W2155849565', 'https://openalex.org/W2156668354', 'https://openalex.org/W2162109087', 'https://openalex.org/W2162507313', 'https://openalex.org/W2165496299', 'https://openalex.org/W2166243852', 'https://openalex.org/W2166295110', 'https://openalex.org/W2166537396', 'https://openalex.org/W2166696244', 'https://openalex.org/W2167040797', 'https://openalex.org/W2168391442', 'https://openalex.org/W2168550692', 'https://openalex.org/W2168811332', 'https://openalex.org/W2170918925', 'https://openalex.org/W2171012458', 'https://openalex.org/W2176371198', 'https://openalex.org/W2324839688', 'https://openalex.org/W2324964169', 'https://openalex.org/W2328859150', 'https://openalex.org/W2329429905', 'https://openalex.org/W2951303532', 'https://openalex.org/W4238557961', 'https://openalex.org/W576420132'], 'related_works': ['https://openalex.org/W638577851', 'https://openalex.org/W4388282505', 'https://openalex.org/W4255657129', 'https://openalex.org/W4242417330', 'https://openalex.org/W3198631238', 'https://openalex.org/W3135997498', 'https://openalex.org/W3013372948', 'https://openalex.org/W2968354375', 'https://openalex.org/W2889550857', 'https://openalex.org/W2359440920'], 'abstract_inverted_index': {'Microorganisms': [0], 'are': [1, 17], 'found': [2], 'throughout': [3], 'nature,': [4], 'thriving': [5], 'in': [6, 72, 86, 115, 167, 195, 244], 'a': [7, 87, 160], 'vast': [8], 'range': [9, 162], 'of': [10, 15, 30, 34, 45, 56, 64, 69, 83, 96, 99, 106, 130, 137, 163, 176, 184, 192, 203, 227], 'environmental': [11, 52, 164], 'conditions.': [12], 'The': [13], 'majority': [14], 'them': [16], 'unculturable': [18], 'or': [19, 40, 141, 151], 'difficult': [20, 150], 'to': [21, 93, 153, 157, 231, 237], 'culture': [22], 'by': [23, 103], 'traditional': [24], 'methods.': [25], 'Metagenomics': [26], 'enables': [27], 'the': [28, 43, 57, 62, 67, 79, 94, 104, 116, 128, 182, 201, 217, 225, 245], 'study': [29], 'all': [31], 'microorganisms,': [32], 'regardless': [33], 'whether': [35], 'they': [36], 'can': [37, 90], 'be': [38, 91, 149], 'cultured': [39], 'not,': [41], 'through': [42], 'analysis': [44], 'genomic': [46], 'data': [47], 'obtained': [48], 'directly': [49], 'from': [50], 'an': [51], 'sample,': [53], 'providing': [54], 'knowledge': [55], 'species': [58], 'present': [59], 'and': [60, 81, 118, 155, 169, 197, 205, 223, 247], 'allowing': [61], 'extraction': [63], 'information': [65], 'regarding': [66], 'functionality': [68], 'microbial': [70], 'communities': [71], 'their': [73], 'natural': [74], 'habitat.': [75], 'Function-based': [76], 'screenings,': [77], 'following': [78], 'cloning': [80], 'expression': [82], 'metagenomic': [84, 220, 229], 'DNA': [85], 'heterologous': [88], 'host,': [89], 'applied': [92], 'discovery': [95, 183], 'novel': [97, 139, 185, 239], 'proteins': [98], 'industrial': [100, 204], 'interest': [101], 'encoded': [102], 'genes': [105, 240], 'previously': [107], 'inaccessible': [108], 'microorganisms.': [109], 'Functional': [110], 'metagenomics': [111], 'has': [112], 'considerable': [113], 'potential': [114, 226], 'food': [117, 168, 196, 246], 'pharmaceutical': [119, 170, 248], 'industries,': [120], 'where': [121], 'it': [122], 'can,': [123], 'for': [124], 'instance,': [125], 'aid': [126], '(i)': [127], 'identification': [129], 'enzymes': [131], 'with': [132, 241], 'desirable': [133], 'technological': [134], 'properties,': [135], 'capable': [136], 'catalysing': [138], 'reactions': [140], 'replacing': [142], 'existing': [143], 'chemically': [144], 'synthesized': [145], 'catalysts': [146], 'which': [147], 'may': [148], 'expensive': [152], 'produce,': [154], 'able': [156], 'work': [158], 'under': [159], 'wide': [161], 'conditions': [165, 175], 'encountered': [166], 'processing': [171], 'cycles': [172], 'including': [173, 187], 'extreme': [174], 'temperature,': [177], 'pH,': [178], 'osmolarity,': [179], 'etc;': [180], '(ii)': [181], 'bioactives': [186], 'antimicrobials': [188], 'active': [189], 'against': [190], 'microorganisms': [191], 'concern': [193], 'both': [194], 'medical': [198], 'settings;': [199], '(iii)': [200], 'investigation': [202], 'societal': [206], 'issues': [207], 'such': [208], 'as': [209, 233], 'antibiotic': [210], 'resistance': [211], 'development.': [212], 'This': [213], 'review': [214], 'article': [215], 'summarizes': [216], 'state-of-the-art': [218], 'functional': [219, 228], 'methods': [221], 'available': [222], 'discusses': [224], 'approaches': [230], 'mine': [232], 'yet': [234], 'unexplored': [235], 'environments': [236], 'discover': [238], 'biotechnological': [242], 'application': [243], 'industries.': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1485657158', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 17}, {'year': 2021, 'cited_by_count': 14}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-13T23:56:27.826315', 'created_date': '2016-06-24'}