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3114, 3125, 3129, 3131, 3158, 3188, 3208, 3210, 3214, 3219, 3229, 3232, 3235, 3245, 3265, 3296, 3332, 3340, 3359, 3392, 3415, 3450, 3505, 3517, 3524, 3533, 3545, 3580, 3597, 3612, 3622, 3633, 3652, 3659, 3668, 3674, 3685, 3726, 3764, 3767, 3802, 3804, 3811, 3817, 3824, 3833, 3848, 3854, 3884, 3901, 3908, 3925, 3928, 3935, 3946, 3962, 3976, 3999, 4014, 4020, 4032, 4054, 4056, 4062, 4083, 4093, 4101, 4120, 4132, 4144, 4162, 4200, 4221, 4237, 4251, 4264, 4278, 4291, 4304, 4313, 4323, 4338, 4351, 4367, 4379, 4419, 4439, 4470, 4495, 4509, 4523, 4544, 4576, 4610, 4633, 4667, 4691, 4727, 4767, 4796, 4834, 4848, 4861, 4889, 4907, 4916, 4931, 4968, 4992, 5004, 5012, 5018, 5021, 5031, 5055, 5069, 5082, 5105, 5122, 5132], 'biosynthesis': [12], 'metalloprotease': [14, 671, 725, 824, 1149, 1265, 1295, 1346, 1749, 1784, 3481, 3497, 3675, 4403, 4496, 4919], 'Aeromonas': [16, 596, 826, 861, 876, 897, 924, 936, 954, 984, 994, 1380, 3393, 3520, 3660, 3930, 3963, 4015, 4057, 4103, 4146, 4184, 4227, 4499, 4853, 4996, 5059], 'sobria': [17, 597, 603, 647, 674, 679, 808, 827, 833, 1054, 1139, 1153, 1212, 1260, 1268, 1298, 1308, 1493, 1498, 1504, 1525, 1538, 1636, 1654, 1720, 1729, 1755, 1761, 1787, 1903, 1998, 2003, 2044, 2267, 2329, 2620, 2634, 2676, 2881, 3145, 3352, 3551, 3605, 3769, 4185], 'by': [18, 51, 78, 105, 123, 158, 187, 216, 245, 275, 302, 329, 347, 382, 411, 440, 469, 633, 672, 726, 1052, 1074, 1120, 1189, 1245, 1328, 1332, 1364, 1447, 1462, 1619, 1845, 1942, 1955, 2082, 2134, 2147, 2165, 2190, 2193, 2274, 2368, 2406, 2478, 2521, 2551, 2608, 2685, 2809, 2932, 3108, 3136, 3170, 3180, 3224, 3380, 3430, 3443, 3519, 3538, 3589, 3629, 3640, 3677, 3721, 3806, 3838, 3860, 3870, 4068, 4183, 4226, 4282, 4405, 4498, 4526, 4718, 5058], 'sodium': [19, 610, 837, 850, 2756, 2760, 4021, 4063], 'chloride': [20, 611, 838, 4064], 'in': [21, 138, 362, 606, 636, 653, 664, 682, 690, 709, 734, 746, 753, 763, 766, 782, 788, 806, 866, 880, 885, 893, 894, 900, 925, 938, 1003, 1015, 1024, 1029, 1076, 1093, 1104, 1132, 1204, 1253, 1276, 1288, 1336, 1352, 1406, 1472, 1558, 1569, 1588, 1596, 1610, 1628, 1640, 1663, 1693, 1706, 1742, 1768, 1777, 1803, 1875, 1935, 1985, 1992, 2007, 2019, 2075, 2129, 2141, 2167, 2176, 2200, 2218, 2235, 2276, 2300, 2311, 2317, 2337, 2473, 2570, 2588, 2610, 2624, 2641, 2656, 2664, 2692, 2727, 2737, 2856, 2939, 2967, 2987, 2992, 3004, 3022, 3028, 3047, 3060, 3063, 3079, 3089, 3096, 3116, 3121, 3151, 3237, 3277, 3288, 3308, 3321, 3356, 3363, 3370, 3394, 3401, 3417, 3485, 3540, 3549, 3554, 3584, 3603, 3607, 3650, 3661, 3716, 3735, 3736, 3778, 3790, 3798, 3813, 3831, 3846, 3868, 3932, 3965, 4017, 4059, 4148, 4186, 4216, 4533, 4616, 4755, 4877, 4923, 4954, 4995], 'the': [22, 549, 559, 591, 626, 634, 637, 639, 660, 665, 668, 683, 686, 705, 722, 729, 735, 749, 754, 776, 789, 792, 811, 931, 946, 951, 963, 977, 1012, 1030, 1066, 1069, 1077, 1089, 1113, 1125, 1146, 1160, 1182, 1200, 1207, 1224, 1246, 1255, 1277, 1322, 1333, 1337, 1345, 1353, 1365, 1376, 1448, 1455, 1463, 1473, 1518, 1559, 1597, 1603, 1622, 1631, 1694, 1744, 1846, 1852, 1867, 1932, 1945, 2020, 2072, 2076, 2083, 2086, 2122, 2125, 2130, 2151, 2168, 2181, 2187, 2194, 2212, 2219, 2224, 2227, 2251, 2263, 2284, 2290, 2295, 2352, 2366, 2392, 2402, 2412, 2442, 2455, 2483, 2498, 2507, 2562, 2571, 2574, 2589, 2592, 2602, 2611, 2636, 2652, 2669, 2681, 2717, 2728, 2768, 2772, 2792, 2822, 2830, 2842, 2847, 2857, 2869, 2896, 2902, 2910, 2914, 2942, 2952, 2955, 2978, 2981, 2993, 2997, 3002, 3013, 3037, 3055, 3194, 3230, 3233, 3238, 3263, 3309, 3333, 3348, 3387, 3390, 3418, 3439, 3448, 3502, 3513, 3522, 3525, 3541, 3564, 3581, 3595, 3598, 3610, 3623, 3634, 3657, 3662, 3692, 3742, 3762, 3765, 3786, 3825, 3843, 3873, 3899, 3966, 4099, 4112, 4219, 4252, 4305, 4677, 4818, 5016, 5019], 'medium': [23, 607, 666, 691, 711, 767, 790, 901, 1094, 1105, 1133, 1205, 1474, 1480, 1571, 1612, 1642, 1665, 1879, 1974, 1986, 2009, 2017, 2236, 2245, 2304, 2318, 2577, 2595, 2626, 2642, 2657, 2693, 3005, 3029, 3064, 3090, 3097, 3278, 3292, 3487, 3556, 3779], 'Eizo': [24, 26, 248, 250, 480], 'Takahashi,': [25, 249, 481], 'Takahashi': [27, 251, 4168, 4206, 4474], 'Laboratory': [28, 57, 84, 164, 193, 222, 252, 281, 308, 388, 417, 446, 482], 'Protein': [30, 166, 195, 224, 254, 390, 419, 448, 484], 'Function,': [31, 167, 196, 225, 255, 391, 420, 449, 485], 'Graduate': [32, 168, 197, 226, 256, 392, 421, 450, 486], 'School': [33, 169, 198, 227, 257, 393, 422, 451, 487], 'Medicine,': [35, 171, 200, 229, 259, 395, 424, 453, 489], 'Dentistry': [36, 172, 201, 230, 260, 396, 425, 454, 490], 'Pharmaceutical': [38, 64, 91, 174, 203, 232, 262, 288, 315, 398, 427, 456, 492], 'Sciences,': [39, 65, 92, 175, 204, 233, 263, 289, 316, 399, 428, 457, 493], 'Okayama': [40, 133, 176, 205, 234, 264, 357, 400, 429, 458, 494, 499, 4195], 'University,': [41, 68, 95, 177, 206, 235, 265, 292, 319, 401, 430, 459, 495], '1-1-1,': [42, 178, 207, 236, 266, 402, 431, 460], 'Tsushima-Naka,': [43, 179, 208, 237, 267, 403, 432, 461, 497], 'Kitaku,': [44, 180, 209, 238, 268, 404, 433, 462, 498], 'Okayama,': [45, 46, 181, 182, 210, 211, 239, 240, 269, 270, 405, 406, 434, 435, 463, 464], '700-8530Search': [47, 183, 212, 241, 271, 407, 436, 465], 'for': [48, 75, 102, 120, 135, 155, 184, 213, 242, 272, 299, 326, 344, 359, 379, 408, 437, 466, 813, 1414, 1436, 1808, 1838, 1924, 2226, 2373, 2395, 2422, 2559, 2573, 2680, 2687, 2710, 2771, 2795, 2802, 2837, 2863, 2891, 2944, 2983, 3015, 3162, 3200, 3303, 3386, 3405, 3656, 3876, 3895, 4608, 4914], 'more': [49, 76, 103, 121, 156, 185, 214, 243, 273, 300, 327, 345, 380, 409, 438, 467, 715, 771, 2646, 3033, 3101, 3282, 3560, 3783], 'papers': [50, 77, 104, 122, 157, 186, 215, 244, 274, 301, 328, 346, 381, 410, 439, 468], 'this': [52, 79, 106, 124, 159, 188, 217, 246, 276, 303, 330, 348, 383, 412, 441, 470, 568, 622, 658, 744, 1163, 1196, 1282, 2474, 3268, 3722], 'authorHidetomo': [53, 277], 'Kobayashi,': [54, 278], 'Hidetomo': [55, 279], 'Kobayashi': [56, 280, 4478], 'Molecular': [59, 86, 283, 310, 4246], 'Microbiological': [60, 87, 284, 311], 'Science,': [61, 88, 285, 312], 'Faculty': [62, 89, 286, 313], 'Hiroshima': [66, 72, 93, 99, 290, 296, 317, 323], 'International': [67, 94, 291, 318], '5-1-1': [69, 96, 293, 320], 'Hiro-Koshingai,': [70, 97, 294, 321], 'Kure,': [71, 98, 295, 322], '737-0112,': [73, 100, 297, 324], 'JapanSearch': [74, 101, 298, 325], 'authorHiroyasu': [80, 304], 'Yamanaka,': [81, 305], 'Hiroyasu': [82, 306], 'Yamanaka': [83, 307, 4480, 5043], 'authorGopinath': [107, 331], 'Balakrish': [108, 111, 332, 335], 'Nair,': [109, 333], 'Gopinath': [110, 334], 'Nair': [112, 336, 4482], 'National': [113, 337], 'Institute': [114, 338, 2513], 'Cholera': [116, 340], 'Enteric': [118, 342], 'DiseasesSearch': [119, 343], 'authorYoshifumi': [125, 349], 'Takeda,': [126, 350], 'Yoshifumi': [127, 351], 'Takeda': [128, 352, 4210, 4484], 'Collaborative': [129, 353], 'Research': [130, 354, 3878], 'Center': [131, 355], 'University': [134, 358], 'Infectious': [136, 360, 3881], 'Diseases': [137, 361], 'India,': [139, 363], 'First': [140, 364, 472], 'Floor,': [141, 365], 'DRCC': [142, 366], 'Building,': [143, 367], 'ID': [144, 368], 'Hospital': [145, 369], 'Campus': [146, 370], '57,': [147, 371], 'Dr.': [148, 372], 'S.C.': [149, 373], 'Banerjee': [150, 374], 'Road,': [151, 375], 'Beliaghata,': [152, 376], 'Kolkata-700010,': [153, 377], 'IndiaSearch': [154, 378], 'authorSakae': [160, 384], 'Arimoto,': [161, 385], 'Sakae': [162, 386], 'Arimoto': [163, 387, 4486], 'authorTomoe': [189, 413], 'Negishi,': [190, 414], 'Tomoe': [191, 415], 'Negishi': [192, 416, 4488], 'authorKeinosuke': [218, 442], 'Okamoto,': [219, 443], 'Keinosuke': [220, 444], 'Okamoto': [221, 445, 4178, 4212, 4490, 5049], 'author': [247, 471], 'published:': [473], '29': [474, 4892], 'October': [475], '2010': [476], 'https://doi.org/10.1111/j.1348-0421.2010.00282.xCitations:': [477], '6': [478, 2110, 2688, 3163, 4086], 'Correspondence': [479], '1-1-1': [496], '700-8530,': [500], 'Japan.Tel:': [501], '81': [502, 507], '86': [503, 508], '251': [504, 509], '7927;': [505], 'fax:': [506], '7926;': [510], 'e-mail:': [511], '[email protected]': [512], 'AboutSectionsPDF': [513], 'ToolsRequest': [514], 'permissionExport': [515], 'citationAdd': [516], 'to': [517, 539, 562, 616, 748, 911, 962, 988, 1001, 1027, 1099, 1179, 1222, 1520, 1980, 2120, 2186, 2268, 2280, 2288, 2294, 2380, 2386, 2511, 2638, 2650, 2767, 2824, 2844, 2909, 3070, 3212, 3243, 3300, 3323, 3335, 3342, 3347, 3368, 3399, 3428, 3437, 3460, 3494, 3501, 3511, 3609, 3646, 3672, 3822, 4654, 4816, 5087], 'favoritesTrack': [518], 'citation': [519], 'ShareShare': [520], 'Give': [521], 'accessShare': [522, 525], 'full': [523], 'text': [524], 'full-text': [526, 541, 565], 'accessPlease': [527], 'review': [528], 'our': [529, 3727], 'Terms': [530, 553], 'Conditions': [532, 555], 'Use': [534], 'check': [536], 'box': [537], 'below': [538, 561], 'share': [540, 563], 'version': [542, 566], 'article.I': [544], 'have': [545, 587, 1011, 1122, 1517, 3457], 'read': [546], 'accept': [548], 'Wiley': [550, 3943, 4029, 4129, 4234, 4376, 4506, 4541, 4664, 5028, 5066], 'Online': [551, 3944, 4030, 4130, 4235, 4377, 4507, 4542, 4665, 5029, 5067], 'Library': [552], 'UseShareable': [557], 'LinkUse': [558], 'link': [560], 'a': [564, 579, 655, 695, 905, 1060, 1219, 1284, 1451, 1581, 1589, 1660, 1769, 1958, 2138, 2174, 2388, 2434, 2447, 2715, 2741, 2812, 3290, 3480, 3695, 3709, 3750, 3809, 3893, 4279, 4614, 4756, 4781, 4785, 4917], 'article': [569], 'with': [570, 1391, 1822, 1927, 2011, 2067, 2335, 2344, 2410, 2416, 2532, 2537, 2747, 2901, 2913, 2948, 2989, 3012, 3042, 3155, 3165, 3198, 3483, 4342, 4564], 'your': [571], 'friends': [572], 'colleagues.': [574], 'Learn': [575], 'more.Copy': [576], 'URL': [577], 'Share': [578], 'linkShare': [580], 'onFacebookTwitterLinked': [581], 'InRedditWechat': [582], 'ABSTRACT': [583], 'The': [584, 756, 797, 967, 1048, 1079, 1148, 1170, 1318, 1341, 1371, 1430, 1534, 1725, 1854, 1878, 1917, 2016, 2060, 2325, 2468, 2583, 2678, 2724, 2732, 2800, 2818, 2835, 2860, 2922, 3141, 3217, 3226, 3492, 3543, 3664, 3829, 3985, 4807], 'present': [585], 'authors': [586], 'previously': [588, 1156], 'shown': [589, 2156, 2199, 2938, 3046], 'that': [590, 621, 743, 775, 912, 950, 974, 983, 993, 998, 1006, 1042, 1065, 1100, 1124, 1180, 1232, 1344, 1357, 1512, 1536, 1548, 1677, 1683, 1984, 2157, 2170, 2180, 2262, 2601, 2618, 2961, 3054, 3073, 3084, 3213, 3244, 3272, 3350, 3364, 3389, 3400, 3471, 3531, 3563, 3578, 3594, 3620, 3673, 3683, 3705, 3713, 3730, 3761, 3816, 3852], 'serine': [592, 643, 829, 1256, 1291, 1592, 1625, 1745, 1780, 3818, 4222], 'protease': [593, 644, 830, 1020, 1185, 1257, 1292, 1324, 1444, 1593, 1626, 1746, 1781, 2285, 3337, 3819, 4223, 4280, 4606], 'activity': [594, 805, 1081, 1119, 1378, 1710, 1842, 2286, 4340], 'is': [598, 604, 630, 780, 917, 1021, 1072, 1085, 1091, 1130, 1177, 1460, 1565, 1594, 1679, 2022, 2161, 2183, 2490, 2606, 3361, 3396, 3536, 3567, 3587, 3626, 3637, 3644, 3654, 3670, 3680, 3689, 3719, 3732, 3770, 3808, 3820, 3836, 3840, 4875, 4912], 'markedly': [599, 957], 'decreased': [600, 745, 956, 3069, 3548], 'when': [601, 685, 704, 1088, 1102, 3075, 3773], 'A.': [602, 646, 673, 678, 727, 807, 832, 1053, 1138, 1152, 1211, 1307, 1492, 1497, 1503, 1524, 1537, 1635, 1653, 1719, 1728, 1760, 1902, 1997, 2002, 2043, 2266, 2328, 2619, 2633, 2665, 2675, 2873, 2880, 3117, 3144, 3351, 3550, 3585, 3604, 3706, 3717, 3768, 3921], 'cultured': [605, 689, 708, 765, 1092, 1103, 1802, 1899, 1921, 2040, 2064, 2334, 3027, 3553, 3777], 'containing': [608, 692, 712, 768, 902, 1095, 1106, 1134, 1386, 1426, 1481, 1572, 1613, 1643, 1666, 1817, 1884, 1912, 1975, 1987, 2025, 2055, 2237, 2246, 2305, 2578, 2596, 2627, 2643, 2694, 2781, 3006, 3030, 3065, 3091, 3098, 3240, 3279, 3488, 3557, 3780], '3.0%': [609, 1096, 1135, 1646, 1669, 1976, 2101, 2281, 2628], '(NaCl,': [612], 'concentration': [613, 696, 750, 906, 1959, 2389, 3611], 'almost': [614], 'equivalent': [615], 'sea': [617], 'water': [618, 873, 961, 4150, 4190], 'salinity),': [619], 'occurs': [623], 'because,': [624], 'although': [625, 3284, 3785], 'synthesis': [627, 3532], 'ASP': [629, 815, 828, 1056, 1071, 1080, 1118, 1129, 1144, 1237, 1514, 1552, 1735, 3834], 'not': [631, 650, 702, 761, 1010, 1369, 1530, 1543, 1556, 1607, 1658, 1680, 1688, 1953, 1968, 2162, 2272, 2586, 3095, 3275, 3568, 3615, 3733, 3747], 'disturbed': [632, 1131], 'salt': [635, 663], 'medium,': [638, 2178], 'maturation': [640, 793, 1126, 1604, 3826], 'pathway': [641, 794, 1127, 1605, 3827, 4494], '(ASP)': [648], 'does': [649, 1606, 1687], 'proceed': [651, 1608], 'successfully': [652, 1609], 'such': [654, 3289, 3313, 3381, 3408, 3571], 'medium.': [656, 755, 1018, 1724, 1863, 1877, 2612, 2994], 'In': [657, 1059, 1195, 1281, 1478, 1973, 2150, 2242, 2556, 2648, 2976, 3267, 3749], 'study,': [659, 1062, 1197, 1283, 3269], 'effect': [661, 1014, 1201, 1372, 1868, 2653], 'on': [667, 1206, 1375, 1722, 1813, 1871, 2319, 2454, 2658, 2895, 3193, 3262, 3880, 4098, 4444, 4567], 'production': [669, 723, 1067, 1208, 1225, 1441, 1623, 1872, 2158, 2320, 2603, 2661, 3113, 3516, 3684, 3715, 3803, 3832, 3847, 3853, 4182, 4220, 4915, 4994], '(AMP)': [675], 'was': [676, 701, 737, 741, 760, 971, 1216, 1304, 1326, 1381, 1445, 1791, 1843, 1857, 1881, 1905, 1940, 1952, 1965, 2048, 2063, 2080, 2144, 2155, 2233, 2271, 2298, 2333, 2359, 2378, 2431, 2476, 2509, 2519, 2585, 2708, 2722, 2730, 2786, 2807, 2854, 2887, 2899, 2958, 2964, 3020, 3068, 3086, 3149, 3191, 3222, 3248, 3274, 3866], 'examined.': [677], 'produced': [680, 703, 1051, 1188, 1241, 2192, 3276, 3734, 4281, 4404, 4497, 5057], 'AMP': [681, 700, 804, 823, 1142, 1176, 1516, 1554, 1678, 1685, 1874, 2322, 2451, 2463, 2471, 2605, 2640, 2663, 3115, 3273, 3484, 3518, 3669, 3731, 3805], 'milieu': [684, 4225], 'bacteria': [687, 706, 1026, 1043, 3297, 3367, 3416, 3440, 3775, 3787, 4681, 4714], 'were': [688, 707, 1272, 1274, 1302, 1404, 1420, 1432, 1766, 1801, 1920, 2118, 2132, 2258, 2414, 2444, 2458, 2535, 2568, 2683, 2735, 2866, 2929, 3077, 3168, 3260], '(NaCl)': [693], 'at': [694, 904, 1412, 1434, 1483, 1574, 1698, 1806, 1836, 1886, 1922, 1947, 1957, 1971, 2027, 2065, 2088, 2106, 2349, 2370, 2398, 2497, 2690, 2798, 3160, 4065], '0.5%.': [698], 'However,': [699, 892, 1523, 2632], 'salty': [710, 783, 1611, 3291, 3572], '1.5%': [713, 769, 1961, 2096, 2247, 2306, 2597, 2644, 3031, 3066, 3099, 3280, 3558, 3781, 3791], 'or': [714, 770, 1186, 1682, 1962, 2629, 2645, 3032, 3100, 3281, 3559, 3782], 'NaCl.': [716, 772, 1916, 1989, 2015, 2059, 2241, 2582, 2631, 2647, 3034, 3081, 3102, 3641, 3800], 'To': [717], 'examine': [718, 2651], 'how': [719, 4680], 'NaCl': [720, 752, 787, 802, 836, 903, 1075, 1108, 1121, 1136, 1203, 1374, 1395, 1482, 1573, 1615, 1620, 1647, 1670, 1697, 1826, 1870, 1885, 1956, 2026, 2166, 2275, 2316, 2348, 2609, 2655, 2698, 2991, 3010, 3067, 3109, 3159, 3242, 3490, 3539, 3590, 3613, 3807, 3839], 'reduces': [721], 'sobria,': [728, 2666], 'amount': [730, 2670, 2718, 3056, 3207, 3544], 'amp': [732, 759, 779, 2672, 2805, 2984, 3058, 3085, 3107, 3132, 3201, 3211, 3236, 3534, 3546, 3565, 3624, 3653], 'mRNA': [733, 757, 2673, 3059, 3130, 3209, 3535, 3547, 3596], 'cell': [736, 1287, 1355, 1776, 2195, 3696], 'measured': [738, 1941, 2081, 2668, 3036, 3223], 'it': [740, 1000, 2154, 3365, 3701, 3740], 'found': [742, 949, 1101, 3074, 3271], 'proportion': [747, 3608], 'detected': [762, 2133, 2146, 2234, 2459, 2536, 2569, 2587, 2907, 3021], 'cells': [764, 2123, 2367, 2729, 3026, 3061, 3285, 3320, 3328], 'This': [773, 1457, 1617, 1675, 2260, 3082, 3345, 3383, 3617, 3850, 3864], 'means': [774, 2261, 3083], 'transcription': [777, 3105, 3579, 3621, 3632], 'inhibited': [781, 3628], 'condition.': [784], 'As': [785, 1585, 2137, 2198, 2714, 2937, 3045], 'described,': [786], 'disturbs': [791], 'ASP.': [796], 'mode': [798], 'action': [800, 1464], 'whereby': [801], 'suppresses': [803], 'differs': [809], 'from': [810, 945, 959, 976, 1306, 1859, 2124, 2205, 2221, 2244, 2303, 2365, 2576, 2594, 2821, 2829, 2841, 2868, 3001, 3025, 3256, 3326, 3441, 3842, 3872, 3898, 4108, 4618, 4851, 5084], 'mechanism': [812, 1114, 3698], 'suppressing': [814], 'activity.': [816], 'List': [817], 'Abbreviations:': [819], 'ALH': [820, 2140, 2160, 2171, 2232, 2257, 2270, 2293, 2453, 2518, 2525, 2623, 3602], 'aerolysin-like': [821], 'hemolysin': [822, 3582], 'DIG': [834, 2773, 2915], 'digoxygenin': [835], 'NB': [839, 1407], 'nutrient': [840, 1384, 1423, 1804, 1814, 1882, 1910, 2023, 2053, 2341, 3152], 'broth': [841, 1805, 1883, 1911, 2024, 2054, 2342, 3153], 'PVDF': [842, 2448, 2456], 'polyvinylidene': [843], 'fluoride': [844], 'rRNA': [845, 2721, 2839, 2852, 2865, 2946, 2963, 3135, 3247], 'ribosomal': [846], 'ribonucleic': [847, 5125], 'acid': [848, 858, 1173, 2495, 2827, 3666], 'SDS-PAGE': [849], 'dodecyl': [851], 'sulfate': [852], 'polyacrylamide': [853, 5085], 'gel': [854, 2438], 'electrophoresis': [855], 'TCA': [856, 2376], 'trichloroacetic': [857], 'Motile': [859], 'mesophilic': [860], 'spp.': [862, 877, 937, 955, 985, 3931, 4147, 4854], 'are': [863, 878, 887, 922, 986, 1055, 1240, 3298, 3413, 3426, 3509, 3776], 'widely': [864], 'distributed': [865], 'aquatic': [867], 'environments,': [868], 'including': [869], 'fresh': [870, 881], 'brackish': [872, 939, 960, 4149], '(1-3).': [874], 'Although': [875], 'abundant': [879], 'water,': [882, 2739, 3477], 'their': [883, 4458], 'numbers': [884], 'seawater': [886, 914, 3395], 'extremely': [888, 1086], 'low': [889, 1087, 3397], '(3,': [890], '4).': [891], 'vitro': [895, 3737], 'culture,': [896, 2223], 'can': [898, 1044, 2621, 3478, 3788], 'grow': [899, 3286, 3789], '3.0%,': [908, 1577], 'which': [909, 1254, 1289, 1468, 1743, 1778, 2489, 2530, 3474, 3835], 'corresponds': [910], '(4-6).': [915], 'It': [916, 1564, 3466, 3679, 3758], 'therefore': [918], 'unclear': [919], 'why': [920], 'there': [921], 'few': [923], 'seawater.': [926, 3357, 4192], 'Monfort': [927, 4136], 'Baleux': [929, 4138], 'examined': [930, 1199, 1327, 1866], 'distribution': [932, 3961], 'survival': [934, 3307, 3425, 4143], 'waters': [940], 'about': [942, 1981], '500': [943, 1894, 2035], 'm': [944], 'coast,': [947], 'number': [952, 3391], 'going': [958], 'open': [964], 'lagoon': [965], '(7).': [966], 'rate': [968, 979], 'decrease': [970], 'faster': [972], 'than': [973, 1551], 'estimated': [975], 'dilution': [978], 'they': [981, 3076, 3373], 'proposed': [982], 'subject': [987, 3427], 'marine': [989, 3476], 'stress.': [990], 'We': [991, 3035, 3592], 'deduced': [992, 1171], 'has': [995, 1155, 3467, 3529, 3702, 3708, 4613], 'various': [996, 1913, 2056, 2345, 2695, 3156], 'agents': [997, 1008], 'enable': [999], 'survive': [1002, 1028, 3369, 4682], 'seawater,': [1004], 'these': [1007, 1033, 1418, 1562, 2142, 2533, 2614, 2892, 3327, 3686, 3774, 3855], 'do': [1009, 1555], 'same': [1013, 2858], 'tube': [1016], 'culture': [1017, 1083, 1946, 2087, 2116, 2126, 2177, 2207, 2358, 2362, 2384, 2686, 3003, 3239, 3258, 3738], 'Extracellular': [1019], 'very': [1022], 'important': [1023, 3302, 3362, 3756], 'enabling': [1025], 'environment,': [1031, 2169], 'as': [1032, 1046, 1218, 1242, 2173, 2549, 2889, 2972, 3178, 3250, 3314, 3409, 3795, 3797, 4561, 4780], 'proteases': [1034, 1050, 1244, 1549, 2191, 3435, 3449, 3856, 4560], 'degrade': [1035, 1469, 1521], 'proteins': [1036, 2443, 3360, 5014, 5083], 'into': [1037, 1475, 1907, 2050, 2480, 2526, 4224], 'amino': [1038, 1172, 2494, 2499, 2826, 2831, 3375, 3665], 'acids': [1039, 3376], 'oligopeptides': [1041, 3378], 'use': [1045], 'nutrients.': [1047], 'representative': [1049], 'AMP.': [1058, 1210, 1737, 2504, 2834, 3849], 'previous': [1061, 1229, 1278, 1338, 1590, 1770, 2152], 'we': [1063, 1198, 1586, 1865, 2616, 2667, 3270], 'showed': [1064, 1231, 1343, 3729], 'bio-active': [1070], 'influenced': [1073, 3720], 'surroundings.': [1078, 3542], 'supernatant': [1084, 2131, 2385], 'strain': [1090, 1221, 1247, 1650, 1673, 4650], 'NaCl,': [1097, 1601, 1977, 2282, 3093, 3283, 3561, 3630, 3784, 3794], 'compared': [1098, 3398], '0.5%': [1107, 1486, 1988, 2091, 2238, 2579, 2630, 3007, 3080, 3092, 3241, 3799], '(8,': [1109], '9).': [1110], 'Studies': [1111, 4847], 'reduction': [1116], 'revealed': [1123, 3053, 3530], '(9).': [1137, 1248, 1280, 1340, 1616, 1772, 2197, 3828], 'produces': [1140, 1733], 'both': [1141, 1290, 1513, 1734, 1779, 2250, 2561], 'outside': [1145], 'cell.': [1147], 'gene': [1150, 1164, 1258, 1266, 1293, 1296, 1347, 1366, 1747, 1782, 1785, 2806, 2853, 3566, 3583, 3600, 3625, 3636, 4310, 4411, 4952], '288': [1154, 1213, 1261, 1269, 1299, 1309, 1494, 1499, 1505, 1526, 1539, 1637, 1721, 1730, 1756, 1762, 1788, 1904, 1999, 2004, 2045, 2330, 2882, 3146, 3552], 'been': [1157, 1349, 1362, 1752, 3458, 3468, 3703], 'cloned': [1158], 'sequence': [1161, 1174, 2871, 3667, 4250, 4303], 'determined': [1165], '(GenBank': [1166, 2876], 'Accession': [1167, 2877], 'No.': [1168], 'DQ784565).': [1169], 'similar': [1178, 3671], 'thermolysin': [1183], 'family-type': [1184], 'elastase': [1187, 4255, 4339, 4880], 'Vibrionaceae': [1190], 'Pseudomonas': [1192, 3454, 4253, 4651, 4751, 4810, 4878], 'aeruginosa': [1193, 4254, 4752, 4811, 4879], '(10-15).': [1194], '(asp+,': [1214, 1270, 1495, 1506, 1638, 1731, 2005, 2046, 2331, 2883, 3147], 'amp+)': [1215, 1311, 1656, 2047, 2884], 'used': [1217, 1880, 2018, 2472, 2709, 2888], 'wild-type': [1220, 1712, 1726, 2000, 2326, 3142], 'analyze': [1223], 'protease.': [1227, 4370], 'Our': [1228, 3527], 'experiments': [1230, 1860, 3728], 'two': [1233, 1323], 'kinds': [1234], 'proteases,': [1236, 1467], 'AMP,': [1239, 2560], 'extracellular': [1243, 1466], 'Two': [1249, 1738], 'isogenic': [1250, 1715, 1739], 'mutant': [1251, 1286, 1716, 1740, 1775], 'strains': [1252, 1579, 1717, 1741, 1800, 3927], '(A.': [1259, 1267, 1297, 1754, 1786], '(asp−,': [1262, 1300, 1310, 1500, 1527, 1540, 1655], 'amp+))': [1263], 'amp−))': [1271, 1301], 'deleted': [1273, 1303, 1753], 'prepared': [1275, 1305, 1354, 1767, 1792, 2302, 2477, 2520, 2684, 2808, 2855, 3000, 3024], 'study': [1279, 1771, 3528, 3643], 'deletion': [1285, 1774], 'using': [1312, 1383, 1793, 1861, 2460, 2811], 'suicide': [1313, 1794, 4441], 'vector': [1314, 1795], 'pXAC623': [1315, 1796], '(9,': [1316, 1797], '16).': [1317, 1798], 'desired': [1319], 'mutation': [1320], 'genes': [1325, 1360, 1750], 'Southern': [1329], 'blot': [1330, 2706, 3139], 'analysis': [1331], 'method': [1334], 'described': [1335, 1587, 2550, 3179], 'report': [1339], 'result': [1342, 1856, 3618, 3810], 'had': [1348, 1361, 1751], 'correctly': [1350], 'mutated': [1351], 'no': [1358, 1578, 3018], 'other': [1359, 1550], 'injured': [1363], 'manipulation': [1367], '(data': [1368, 3614, 3746], 'shown).': [1370, 3616, 3748], 'proteolytic': [1377], 'assayed': [1382], 'agar': [1385, 1424, 1479, 1570, 1641, 1664, 1815], '3%': [1387, 1427, 1600, 1614, 1818], 'skim': [1388, 1428, 1819], 'milk': [1389, 1820], 'supplemented': [1390, 1821, 2010, 2343, 3154], 'different': [1392, 1823, 2012, 3257, 3841, 3933, 4066, 4852], 'concentrations': [1393, 1484, 1699, 1824, 1914, 2013, 2057, 2696, 4019, 4061], '(final': [1396, 1827], 'concentrations,': [1397, 1828], '0.5%,': [1398, 1829, 1887, 2028], '1.0%,': [1399, 1830, 1888, 2029, 2700], '2.0%,': [1400, 1890, 2031, 2702], '3.0%).': [1402, 1833], 'Strains': [1403], 'pre-cultured': [1405], '(Eiken': [1408], 'Chemical,': [1409], 'Tokyo,': [1410, 2935], 'Japan)': [1411], '37°C': [1413, 1435, 1807, 1837, 1923, 2066, 2691, 3161], '20': [1415, 1809, 4579], 'hr': [1416, 1810, 1926, 2689, 3164], 'cultures': [1419], 'streaked': [1421, 1812], 'onto': [1422, 2433, 2446, 2788], 'plates': [1425, 1431], 'milk.': [1429], 'incubated': [1433], '48': [1437, 1839], 'hr.': [1438], 'After': [1439, 1834, 2408, 2440], 'incubation,': [1440], 'active': [1443, 1691, 2188, 2254, 2296, 2565], 'assessed': [1446, 1844], 'appearance': [1449, 1847], 'transparent': [1452, 1458, 1509, 1532, 1545, 1583, 1632, 1661], 'zone': [1453, 1459, 1633, 1662], 'around': [1454, 1634, 1851], 'bacteria.': [1456, 1853, 3506, 3526], 'generated': [1461], 'insoluble': [1470], 'casein': [1471], 'soluble': [1476], 'peptide.': [1477], '1.0%': [1488, 2093, 2240, 2581, 3009], 'three': [1489], 'strains,': [1490], 'namely': [1491], 'amp+),': [1496, 1501, 1732, 2006, 2332, 3148], 'amp−),': [1507], 'created': [1508, 1580], 'zones,': [1510], 'showing': [1511, 2960], 'ability': [1519, 2264, 2637, 3334, 3341, 3493, 3924, 4906], 'casein.': [1522], 'amp−)': [1528, 1541, 1639], 'did': [1529, 1542, 1657], 'create': [1531, 1659], 'zones.': [1533, 1563], 'fact': [1535, 3388], 'form': [1544, 2189, 2214, 2230, 2297], 'zones': [1546, 1850], 'shows': [1547], 'participate': [1557], 'formation': [1560], 'also': [1566, 2145, 3469], 'noteworthy': [1567], 'that,': [1568], '2.0%': [1575, 1644, 1667, 1701, 1831, 2098, 3489, 3793], 'clear': [1582, 1849], 'zone.': [1584], 'report,': [1591], 'synthesized': [1595, 1686], 'presence': [1598, 1695], 'but': [1602, 1967, 2283, 3017, 3094], 'disturbance': [1618], 'resulted': [1627], 'disappearance': [1629], '(Fig.': [1648, 1671, 3293], '1,': [1649, 1672], '3).': [1651], 'Similarly,': [1652], '2).': [1674, 3294], 'suggests': [1676], 'synthesized,': [1681], 'any': [1684], 'take': [1689, 3324], 'an': [1690, 2277, 2748, 2973, 3755, 4314], 'form,': [1692], 'more.': [1703, 2308], 'Figure': [1704, 1936, 1990, 2201, 2309, 2940, 3048, 3119], '1Open': [1705], 'figure': [1707, 1993, 2312, 3122], 'viewerPowerPoint': [1708, 1994, 2313, 3123], 'Caseinolytic': [1709], 'its': [1714], 'solid': [1723, 1862], 'strain,': [1727, 2001, 2327, 3143], '[asp−,': [1757, 1789], 'amp+]': [1758], '[asp+,': [1763], 'amp−],': [1764], 'respectively)': [1765], 'A': [1773, 1893, 2034, 4436, 4603, 4628, 4829, 4872, 4963, 5100], 'amp−])': [1790], 'These': [1799], 'plate': [1816, 4072], 'incubation': [1835], 'hr,': [1840, 2113], 'caseinolytic': [1841], 'above': [1855], 'obtained': [1858, 3255], 'Subsequently,': [1864], 'liquid': [1876, 2008, 2625, 3486, 3555], '1.5%,': [1889, 2030, 2701], '3.0%.': [1892, 2033], 'μl': [1895, 2036, 2418, 2427], 'sample': [1896, 2430, 2593], 'overnight': [1898, 2039], 'solution': [1900, 2041, 2377, 2421, 2745], 'inoculated': [1906, 2049], '50': [1908, 2051, 2338], 'ml': [1909, 2052, 2115, 2339, 2356, 2382], 'bacterial': [1918, 1938, 2061, 2078, 3304, 3422, 3434, 4782], 'suspensions': [1919], '24': [1925, 4730], 'shaking': [1928, 2068, 2336], '(140': [1929, 2069], 'rpm).': [1930, 2070], 'At': [1931, 2071, 2109, 2351], 'times': [1933, 2073], 'indicated': [1934, 2074, 2353], '2,': [1937], 'growth': [1939, 1951, 1978, 2079, 3305, 3423, 4100], 'absorbance': [1943, 2084], '620': [1948, 2089, 2107], 'nm.': [1949, 2108], 'Bacterial': [1950, 4559], 'affected': [1954, 2164, 3837, 3845], 'less,': [1963], 'slightly,': [1966], 'significantly,': [1969], 'reduced': [1970], '2%.': [1972], 'dropped': [1979], '50%': [1982], '2Open': [1991], 'Growth': [1995, 4013], 'experiment': [2021, 2475], 'specimen': [2037], 'suspension': [2062], 'figure,': [2077], 'nm.•,': [2090], 'NaCl;○,': [2092], 'NaCl;': [2094, 2099, 2102], '▴,': [2095], 'NaCl;▵,': [2097], '◆,': [2100], 'O.D.620,': [2103], 'optical': [2104], 'density': [2105, 2953, 3038], '12': [2112, 4294], '2': [2114, 2355, 3949], 'samples': [2117, 2143, 2204, 2220, 2243, 2301, 2575, 2679, 2950, 3023], 'centrifuged': [2119], 'separate': [2121], 'supernatant.': [2127], 'AMPs': [2128], 'Western': [2135, 2148], 'blotting.': [2136, 2149], 'comparison,': [2139], 'experiment,': [2153], 'significantly': [2163], 'emerges': [2172], 'precursor': [2175, 2182, 2213, 2252, 2291], 'then': [2184], 'processed': [2185], 'itself': [2196], '3,': [2202], 'all': [2203, 2949], '6-hr': [2206], 'contained': [2208], 'comparable': [2209], 'amounts': [2210, 2346, 3157], 'ALH,': [2216, 2466], 'however,': [2217], '12-hr': [2222], 'band': [2225, 2584], 'mature': [2228, 2503], '(active)': [2229], 'more,': [2249, 2599], 'forms': [2255, 2566], 'present.': [2259], 'produce': [2269, 2622, 2639, 3336, 3479, 3495], 'suppressed': [2273, 2607], 'environment': [2278], 'up': [2279], 'required': [2287, 3645], 'change': [2289], 'weak': [2299, 2986], '3Open': [2310], 'Effect': [2314], 'ALH.': [2324], '37°C.': [2350], 'times,': [2354], 'taken': [2360], 'supernatants': [2363], 'separated': [2364], 'centrifugation': [2369, 3171], '15,000': [2371], '×g': [2372], '5': [2374, 4035], 'min.': [2375], 'added': [2379], '1.0': [2381], 'reach': [2387], '10.0%,': [2391], 'mixture': [2393, 2780], 'left': [2394], '30': [2396, 2796, 4934], 'min': [2397, 2797], 'room': [2399], 'temperature': [2400], 'precipitates': [2403, 2413], 'yielded': [2404, 3379], 'collected': [2405], 'centrifugation.': [2407], 'rinsing': [2409], 'ethanol,': [2411], 'solubilized': [2415], '100': [2417], 'loading': [2420], 'SDS-': [2423], 'PAGE': [2424], '10': [2426, 2782, 3186, 4240], 'each': [2429, 2956, 3040, 3189, 3220], 'loaded': [2432], 'lane': [2435, 2590], 'SDS-polyacrylamide': [2437], '(32).': [2439], 'electrophoresis,': [2441], 'transferred': [2445], 'membrane': [2449, 2457, 2793, 3195], 'electrophoretically.': [2450], 'antiserum': [2461, 2469, 2508], 'against': [2462, 2465, 2470, 2517, 3463, 4784], 'respectively.': [2467], 'injection': [2479, 2522], 'rabbits': [2481, 2527], 'peptide': [2484], '(NGAYSPLNDAHYFGC-NH2=keyhole': [2485], 'limpet': [2486], 'hemocyanin': [2487], 'conjugate),': [2488], 'composed': [2491], '250–263': [2493], 'residues': [2496, 2828, 2849], 'terminal': [2500, 2832], 'region': [2501], 'Preparation': [2505], 'entrusted': [2510], 'Peptide': [2512], '(Osaka,': [2514], 'Japan).': [2515, 2936], 'Antiserum': [2516], 'purified': [2524, 2733, 3177], '(33).': [2528], 'Proteins': [2529], 'reacted': [2531, 2947, 3011, 3197], 'antisera': [2534], 'horseradish': [2538], 'peroxidase-conjugated': [2539], 'donkey': [2540], 'anti-rabbit': [2541], 'IgG': [2542], '(Amersham': [2543], 'Biosciences,': [2544], 'UK': [2545], 'Limited,': [2546], 'Buckinghamshire,': [2547], 'UK),': [2548], 'Towbin': [2552, 5073], 'et': [2553, 3575], 'al.': [2554], '(34).': [2555], 'contrast,': [2557, 2977], 'bands': [2558], 'intermediate': [2563], '(17),': [2567], 'lanes': [2572], 'indicating': [2600, 3562], 'From': [2613], 'observations,': [2615], 'concluded': [2617], 'loses': [2635], 'order': [2649, 3322], 'suppression': [2659], '288.': [2677], 'assay': [2682, 2707], '(0.5%,': [2699], '3.0%),': [2703], 'dot': [2705, 3138], 'measurement': [2711], 'mRNA.': [2713, 3126], 'control,': [2716], '16S': [2720, 2838, 2851, 2864, 2945, 2962, 3134, 3203, 3215, 3246], 'measured.': [2723], 'total': [2725, 2998, 3173], 'RNA': [2726, 2744, 2785, 2803, 2894, 2999, 3137, 3174, 3190], 'purified.': [2731], 'RNAs': [2734], 'dissolved': [2736], 'RNase-free': [2738], 'portion': [2742], 'mixed': [2746], 'equal': [2749], 'volume': [2750], 'denaturation': [2752], 'buffer': [2753], '(0.18': [2754], 'M': [2755, 2759], 'citrate,': [2757], '1.8': [2758], 'chloride,': [2761], '14.8%': [2762], 'formaldehyde': [2763], '[pH': [2764], '7.0]),': [2765], 'according': [2766, 2908], "manufacturer's": [2769], 'protocol': [2770], 'system': [2774, 3711, 3723], '(Roche': [2775, 2816, 2920], 'Diagnostics,': [2776], 'Mannheim,': [2777], 'Germany).': [2778], 'Each': [2779], 'μg': [2783, 3187], 'spotted': [2787], 'nylon': [2789, 2897], 'membranes,': [2790], 'baked': [2794], '120°C.': [2799], 'probe': [2801, 2819, 2836, 2943, 2982, 3014], 'PCR': [2810], 'DNA': [2813, 2886], 'labeling': [2814], 'kit': [2815], 'Diagnostics).': [2817, 2921], 'covers': [2820], '186th': [2823], '369th': [2825], 'covering': [2840], 'first': [2843], '792nd': [2845], 'nucleotide': [2848, 4249, 4302], 'way.': [2859], 'specific': [2861], 'primers': [2862], 'designed': [2867], 'genome': [2870, 2885], 'hydrophila': [2874, 3586, 3707, 3718, 3964, 4058], 'ATCC7966': [2875], 'Number': [2878], 'CP000462).': [2879], 'template': [2890], 'PCRs.': [2893], 'membranes': [2898], 'hybridized': [2900], 'probe,': [2903], 'hybridization': [2905], 'signals': [2906, 3052], 'manual': [2911], 'supplied': [2912], 'Nucleic': [2916], 'Acid': [2917], 'Detection': [2918, 3124, 3128], 'Kit': [2919], 'detection': [2923], 'chemiluminescence': [2925], 'signal': [2927], 'quantification': [2928, 3050], 'carried': [2930], 'out': [2931], 'LAS3000mini': [2933, 3043], '(Fujifilm,': [2934], '4a,': [2941], 'spot': [2957, 3041, 3221, 3234], 'comparable,': [2959], 'well': [2965, 3088, 3287, 3681, 3796], 'transcribed': [2966, 3087, 3569], 'every': [2968], 'condition': [2969], 'useful': [2971], 'internal': [2974], 'standard.': [2975], 'reaction': [2979, 3019], 'became': [2985], 'parallel': [2988], 'increasing': [2990, 4018, 4060], 'That': [2995], 'is,': [2996], 'amp,': [3016], '(Fujifilm).': [3044], '4b,': [3049], 'grown': [3062, 3078, 3150], '30%': [3071], 'Suppression': [3103], 'causes': [3110], 'inhibition': [3111], 'sobria.': [3118, 4228, 4500, 5060], '4Open': [3120], '(a)': [3127], 'hybridization.': [3140], 'shaking.': [3166], 'Cells': [3167], 'harvested': [3169], 'extracted': [3175], 'Holmes': [3181, 5109], 'Bonner': [3183, 5111], '(35)': [3184], 'fixed': [3192], 'probes': [3199], 'rRNA.': [3204, 3216], '(b)': [3205], 'Relative': [3206], 'intensity': [3218, 3231], 'LAS3000mini.': [3225], 'relative': [3227, 3253], 'value': [3228], 'regarded': [3249], '100%.': [3251], 'Other': [3252], 'values': [3254], 'conditions': [3259], 'calculated': [3261], 'basis': [3264], 'this.': [3266], 'Exotoxins': [3295], 'thought': [3299], 'be': [3301, 3461, 3499, 3760, 3858], 'environment.': [3310, 3663], 'Some': [3311, 3433], 'exotoxins,': [3312], 'cytolysin': [3315], 'protease,': [3317], 'destroy': [3318], 'host': [3319, 4446, 4462, 4759], 'nutrients': [3325], '(18,': [3329], '19).': [3330], 'Loss': [3331], 'induces': [3338], 'loss': [3339], 'decompose': [3343, 3354], 'proteins.': [3344], 'leads': [3346], 'conclusion': [3349], 'cannot': [3353], 'protein': [3355], 'Decomposition': [3358], 'enables': [3366], 'nature,': [3371], 'because': [3372], 'utilize': [3374], 'decomposition.': [3382], 'may': [3384, 3498, 3759], 'account': [3385], 'freshwater.': [3402], 'Bacteriovorous': [3403], 'predators,': [3404], 'example': [3406], 'protozoa': [3407], 'ciliates': [3410], 'flagellates,': [3412], 'predators': [3414, 3431, 3444], 'natural': [3419, 4187, 4619], 'world,': [3420], 'constraints': [3429], '(20-23).': [3432], 'function': [3436, 3763], 'protect': [3438], 'attack': [3442], '(24-26).': [3445], 'For': [3446], 'example,': [3447], 'Vibrio': [3451, 3472, 4105, 4283, 4306, 4343, 4368, 4406, 4568, 4604, 4908], '(20)': [3452], '(21,': [3455], '26)': [3456], 'reported': [3459, 3470, 3704], 'protectors': [3462], 'predator': [3464, 4620], 'grazing.': [3465, 4621, 4657, 4684], 'vulnificus,': [3473], 'inhabits': [3475], 'homologous': [3482, 3687], '(14).': [3491], 'thermolysin-type': [3496], 'related': [3500], 'native': [3503], 'habitat': [3504, 3523], 'Further': [3507, 3642], 'studies': [3508], 'necessary': [3510], 'clarify': [3512], 'relationship': [3514], 'between': [3515], 'regulated': [3537, 3690], 'under': [3570], 'conditions.': [3573], 'Ørmen': [3574, 4838], 'al': [3576], 'demonstrated': [3577], 'induced': [3588, 3639], '(27).': [3591], 'confirmed': [3593], 'alh': [3599, 3635], 'encoding': [3601], 'increases': [3606], 'indicates': [3619, 3851], 'specifically': [3627, 3771], 'whereas': [3631, 3815], 'positively': [3638], 'show': [3647], 'whether': [3648], 'alteration': [3649], 'expression': [3651, 4525, 4953], 'responsible': [3655], 'ecology': [3658], 'secreted': [3676], 'Vibrionaceae.': [3678], 'known': [3682], 'metalloproteases': [3688], 'via': [3691], 'quorum-sensing': [3693, 3710, 3751], 'system,': [3694, 3752], 'density-dependent': [3697], '(28-30).': [3699], 'Moreover,': [3700], 'exoprotease': [3714, 4993], '(31).': [3724], 'Another': [3725], 'until': [3739], 'enters': [3741], 'middle': [3743], 'logarithmic': [3744], 'phase': [3745], 'autoinducers': [3753], 'play': [3754], 'role.': [3757], 'autoinducer': [3766], 'lost': [3772], 'dysfunction': [3812], 'transcription,': [3814], 'due': [3821], 'disruption': [3823], 'step': [3830, 3844], 'might': [3857], 'controlled': [3859], 'individual': [3861], 'mechanisms.': [3862], 'ACKNOWLEDGMENTS': [3863], 'work': [3865], 'supported': [3867], 'part': [3869], 'grants': [3871], 'Japan': [3874], 'Initiative': [3875], 'Global': [3877], 'Network': [3879], 'Diseases,': [3882], 'Ministry': [3883, 3900], 'Education,': [3885, 3902], 'Culture,': [3886, 3903], 'Sports,': [3887, 3904], 'Science': [3888, 3905], 'technology,': [3890], 'Japan,': [3891], 'grant-in-aid': [3894], 'scientific': [3896], 'research': [3897], 'Technology': [3907], 'Japan.': [3909], 'REFERENCES': [3910], 'Brandi': [3912], 'G.,': [3913, 4424, 4585, 4774], 'Sisti': [3914], 'M.,': [3915, 4173, 4555, 4591, 4742, 4942, 5042, 5046], 'Giardini': [3916], 'F.,': [3917, 4738], 'Schiavano': [3918], 'G.F.,': [3919], 'Albano': [3920], '(1999)': [3922, 4333, 4871, 4986], 'Survival': [3923], 'cytotoxic': [3926], 'motile': [3929, 4145], 'types': [3934], 'water.': [3936], 'Lett': [3937, 4023], 'Appl': [3938, 3969, 4024, 4155, 4658], 'Microbiol': [3939, 3971, 3993, 4025, 4078, 4125, 4157, 4346, 4371, 4465, 4501, 4537, 4660, 4686, 5061], '29:': [3940], '211–': [3941], '5.': [3942, 4631, 5027], 'LibraryCASPubMedWeb': [3945, 4031, 4131, 4236, 4378, 4508, 4543, 4666, 5030, 5068], 'Science®Google': [3947, 3977, 4000, 4033, 4084, 4133, 4163, 4201, 4238, 4265, 4292, 4324, 4352, 4380, 4420, 4471, 4510, 4545, 4577, 4634, 4668, 4692, 4728, 4768, 4797, 4835, 4862, 4890, 4932, 4969, 5005, 5032, 5070, 5106, 5133], 'Scholar': [3948, 3978, 4001, 4034, 4085, 4134, 4164, 4202, 4239, 4266, 4293, 4325, 4353, 4381, 4421, 4472, 4511, 4546, 4578, 4635, 4669, 4693, 4729, 4769, 4798, 4836, 4863, 4891, 4933, 4970, 5006, 5033, 5071, 5107, 5134], 'Hazen': [3950], 'T.C.,': [3951], 'Fliermans': [3952], 'C.B.,': [3953], 'Hirsch': [3954], 'R.P.,': [3955], 'Esch': [3956], 'G.W.': [3957], '(1978)': [3958], 'Prevalence': [3959], 'United': [3967], 'States.': [3968], 'Environ': [3970, 4156, 4659], '36:': [3972, 4927], '731–': [3973], '8.': [3974, 4349, 5130], 'CrossrefCASPubMedWeb': [3975, 3998, 4082, 4263, 4350, 4418, 4469, 4632, 4690, 4726, 4766, 4795, 4833, 4860, 4888, 4930, 4967, 5104, 5131], '3': [3979], 'Janda': [3980, 4327], 'J.M.,': [3981, 4328, 4843, 4981], 'Abbott': [3982, 4329], 'S.L.': [3983], '(2010)': [3984, 4492], 'genus': [3986], 'Aeromonas:': [3987], 'taxonomy,': [3988], 'pathogenicity,': [3989], 'infection.': [3991], 'Clin': [3992], 'Rev': [3994], '23:': [3995], '35–': [3996], '73.': [3997], '4': [4002], 'Delamare': [4003], 'A.P.,': [4004], 'Costa': [4005], 'S.C.,': [4006], 'Da': [4007], 'Silveira': [4008], 'M.M.,': [4009, 4390], 'Echeverrigaray': [4010], 'S.': [4011, 4273, 4332, 4362, 4674, 4710, 4902], '(2000)': [4012], 'species': [4016, 4106], 'chloride.': [4022], '30:': [4026], '57–': [4027], '60.': [4028, 4081], 'Pianetti': [4036], 'A.,': [4037, 4039, 4516, 4518, 4595, 4638, 4704], 'Manti': [4038], 'Boi': [4040], 'P.,': [4041, 4137, 4432, 4708, 4732], 'Citterio': [4042], 'B.,': [4043, 4583], 'Sabatini': [4044], 'L.,': [4045, 4514, 4734, 4740, 4977], 'Papa': [4046], 'S.,': [4047, 4175, 4271, 4360, 4384, 4394, 4396, 4487, 4549, 4551, 4599, 4706, 4801, 4896, 4973], 'Rocchi': [4048], 'M.B.,': [4049, 4938], 'Bruscolini': [4050], 'F.': [4051], '(2008)': [4052, 4180, 4711], 'Determination': [4053], 'viability': [4055], 'temperatures': [4067], 'flow': [4069], 'cytometry': [4070], 'count': [4073], 'technique.': [4074], 'Int': [4075], 'J': [4076, 4123, 4258, 4317, 4570, 4761, 4790, 4883], 'Food': [4077], '127:': [4079], '252–': [4080], 'Wang': [4087], 'Y.,': [4088, 4211, 4386, 4477, 4485, 5036], 'Gu': [4089], 'J.D.': [4090], '(2005)': [4091, 4435, 4675], 'Influence': [4092], 'temperature,': [4094], 'salinity': [4095], 'pH': [4097], 'environmental': [4102], 'isolated': [4107], 'Mai': [4109], 'Po': [4110], 'Inner': [4113], 'Deep': [4114], 'Bay': [4115], 'Nature': [4116, 5024], 'Reserve': [4117], 'Ramsar': [4118], 'Site': [4119], 'Hong': [4121], 'Kong.': [4122], 'Basic': [4124], '45:': [4126], '83–': [4127], '93.': [4128], '7': [4135], 'B.': [4139], '(1991)': [4140, 4299], 'Distribution': [4141], 'receiving': [4151], 'sewage': [4152], 'treatment': [4153], 'effluent.': [4154], '57:': [4158], '2459–': [4159], '67.': [4160], 'CASPubMedWeb': [4161, 4290, 4322, 5003], '8': [4165], 'Khan': [4166, 4204], 'R.,': [4167, 4205], 'E.,': [4169, 4207, 4475, 4640], 'Nakura': [4170], 'H.,': [4171, 4388, 4479, 4481, 4553, 4894, 5040, 5044, 5074], 'Ansaruzzaman': [4172], 'Banik': [4174], 'Ramamurthy': [4176, 4208], 'T.,': [4177, 4209, 4489, 4587, 4898, 5038, 5076], 'K.': [4179, 4213, 4398, 4491, 4557, 5050], 'Toxin': [4181], 'environments:': [4188], 'river': [4189], 'vs.': [4191], 'Acta': [4193], 'Med': [4194], '62:': [4196, 4538], '363–': [4197], '71.': [4198], 'PubMedWeb': [4199], '9': [4203], '(2007)': [4214], 'Salt': [4215], 'surroundings': [4217], 'influences': [4218], 'Microbio': [4229], 'Immunol': [4230, 4372, 4502, 5062], '51:': [4231], '963–': [4232], '76.': [4233], 'Bever': [4241], 'R.A.,': [4242], 'Iglewski': [4243], 'B.H.': [4244], '(1988)': [4245], 'characterization': [4247, 4277, 4337, 4366, 5054], 'structural': [4256, 5013], 'gene.': [4257], 'Bacteriol': [4259, 4318, 4762, 4791, 4884], '170:': [4260], '4309–': [4261], '14.': [4262, 5065], '11': [4267], 'Chowdhury': [4268], 'M.A.,': [4269], 'Miyoshi': [4270, 4355, 4359, 4383, 4550, 4895], 'Shinoda': [4272, 4361, 4393, 4548, 4901], '(1990)': [4274], 'Purification': [4275, 4364, 5052], 'mimicus.': [4284], 'Infect': [4285, 4998], 'Immun': [4286, 4999], '58:': [4287], '4159–': [4288], '62.': [4289], 'Häse': [4295], 'C.C.,': [4296], 'Finkelstein': [4297], 'R.A.': [4298], 'Cloning': [4300], 'cholerae': [4307, 4605], 'hemagglutinin/protease': [4308], '(HA/protease)': [4309], 'construction': [4312], 'HA/protease-negative': [4315], 'strain.': [4316], '173:': [4319], '3311–': [4320], '7.': [4321, 4689], '13': [4326], 'S.L.,': [4330], 'Khashe': [4331], 'Identification': [4334], 'initial': [4336], 'associated': [4341], 'cholerae.': [4344, 4956], 'Curr': [4345], '39:': [4347], '73–': [4348], '14': [4354], 'N.,': [4356], 'Shimizu': [4357], 'C.,': [4358, 4428, 4589, 4672, 4696, 4745], '(1987)': [4363], 'vulnificus': [4369, 4909], '31:': [4373], '13–': [4374], '25.': [4375], '15': [4382], 'Sonoda': [4385], 'Wakiyama': [4387], 'Rahman': [4389, 4554], 'Tomochika': [4391, 4556, 4899], 'K.,': [4392, 4581, 4900, 5048], 'Yamamoto': [4395], 'Tobe': [4397], '(2002)': [4399, 4750, 4806, 4947], 'An': [4400], 'exocellular': [4401], 'thermolysin-like': [4402], 'fluvialis:': [4407], 'purification,': [4408], 'characterization,': [4409], 'cloning.': [4412], 'Microb': [4413, 4855, 4925], 'Pathog': [4414, 4856, 4926], '33:': [4415], '127–': [4416], '34.': [4417, 4966], '16': [4422], 'Demarre': [4423], 'Guérout': [4425], 'A.M.,': [4426], 'Matsumoto-Mashimo': [4427], 'Rowe-Magnus': [4429], 'D.A.,': [4430], 'Marlière': [4431], 'Mazel': [4433], 'D.': [4434], 'new': [4437], 'family': [4438], 'mobilizable': [4440], 'plasmids': [4442], 'based': [4443], 'broad': [4445], 'range': [4447], 'R388': [4448], 'plasmid': [4449, 4453], '(IncW)': [4450], 'RP4': [4452], '(IncPα)': [4454], 'conjugative': [4455], 'machineries': [4456], 'cognate': [4459], 'Escherichia': [4460], 'coli': [4461], 'strains.': [4463], 'Res': [4464], '156:': [4466], '245–': [4467], '55.': [4468], '17': [4473], 'Fujii': [4476, 5035], 'G.B.,': [4483], 'Maturation': [4493], '54:': [4503], '596–': [4504], '605.': [4505], '18': [4512], 'Rajagopal': [4513], 'Vo': [4515], 'Silvestroni': [4517], 'Rubens': [4519], 'C.E.': [4520], '(2006)': [4521, 4602, 4645], 'Regulation': [4522], 'cytotoxin': [4524], 'converging': [4527], 'eukaryotic-type': [4528], 'two-component': [4530], 'signaling': [4531], 'mechanisms': [4532], 'Streptococcus': [4534], 'agalactiae.': [4535], 'Mol': [4536], '941–': [4539], '57.': [4540], '19': [4547], 'Wakae': [4552], '(1996)': [4558], 'pathogenic': [4562], 'factors,': [4563], 'special': [4565], 'emphasis': [4566], 'proteases.': [4569], 'Toxicol': [4571], '15:': [4572], '327–': [4573], '39.': [4574], 'CASWeb': [4575], 'Vaitkevicius': [4580], 'Lindmark': [4582], 'Ou': [4584], 'Song': [4586], 'Toma': [4588], 'Iwanaga': [4590], 'Zhu': [4592, 4935], 'J.,': [4593, 4936], 'Andersson': [4594], 'Hammarström': [4596], 'M.L.,': [4597], 'Tuck': [4598], 'Wai': [4600], 'S.N.': [4601], 'needed': [4607], 'killing': [4609], 'Caenorhabditis': [4611], 'elegans': [4612], 'role': [4615], 'protection': [4617], 'Proc': [4622, 4823, 4957, 5094], 'Natl': [4623, 4824, 4958, 5095], 'Acad': [4624, 4825, 4959, 5096], 'Sci': [4625, 4826, 4960, 5097], 'U': [4626, 4827, 4961, 5098], 'S': [4627, 4828, 4962, 5099], '103:': [4629], '9280–': [4630], '21': [4636], 'Jousset': [4637], 'Lara': [4639], 'Wall': [4641], 'L.G.,': [4642], 'Valverde': [4643], 'C.': [4644], 'Secondary': [4646], 'metabolites': [4647], 'help': [4648], 'biocontrol': [4649], 'fluorescens': [4652], 'CHA0': [4653], 'escape': [4655], 'protozoan': [4656, 4683], '72:': [4661], '7083–': [4662], '90.': [4663], '22': [4670], 'Matz': [4671, 4695], 'Kjelleberg': [4673, 4709], 'Off': [4676], 'hook': [4678], '–': [4679], 'Trends': [4685], '13:': [4687], '302–': [4688], '23': [4694], 'Webb': [4697], 'J.S.,': [4698], 'Schupp': [4699], 'P.J.,': [4700], 'Phang': [4701], 'S.Y.,': [4702], 'Penesyan': [4703], 'Egan': [4705], 'Steinberg': [4707], 'Marine': [4712], 'biofilm': [4713], 'evade': [4715], 'eukaryotic': [4716, 4786], 'predation': [4717], 'targeted': [4719], 'chemical': [4720], 'defense.': [4721], 'PLoS': [4722], 'One': [4723], '3:': [4724], 'e2744.': [4725], 'Cosson': [4731], 'Zulianello': [4733], 'Join-Lambert': [4735], 'O.,': [4736], 'Faurisson': [4737], 'Gebbie': [4739], 'Benghezal': [4741], 'Van': [4743], 'Delden': [4744], 'Curty': [4746], 'L.K.,': [4747], 'Köhler': [4748], 'T.': [4749], 'virulence': [4753, 4814, 4951], 'analyzed': [4754], 'Dictyostelium': [4757, 4821], 'discoideum': [4758], 'system.': [4760], '184:': [4763], '3027–': [4764], '33.': [4765], '25': [4770], 'Lainhar': [4771], 'W.,': [4772], 'Stolfa': [4773], 'Koudelka': [4775], 'G.B.': [4776], '(2009)': [4777], 'Shiga': [4778], 'toxin': [4779], 'defense': [4783], 'predator,': [4787], 'Tetrahymena': [4788], 'thermophila.': [4789], '191:': [4792], '5116–': [4793], '22.': [4794], '26': [4799], 'Pukatzki': [4800], 'Kessin': [4802], 'R.H.,': [4803], 'Mekalanos': [4804], 'J.J.': [4805, 4946], 'human': [4808], 'pathogen': [4809], 'utilizes': [4812], 'conserved': [4813], 'pathways': [4815], 'infect': [4817], 'social': [4819], 'amoeba': [4820], 'discoideum.': [4822], '99:': [4830, 4964], '3159–': [4831], '64.': [4832], '27': [4837], 'Ø.,': [4839], 'Regue': [4840], 'M.Q.,': [4841], 'Tomás': [4842, 4980], 'Granum': [4844], 'P.E.': [4845], '(2003)': [4846], 'aerolysin': [4849], 'promoters': [4850], '35:': [4857], '189–': [4858], '96.': [4859], '28': [4864], 'Anderson': [4865], 'R.M.,': [4866], 'Zimprich': [4867], 'C.A.,': [4868], 'Rust': [4869], 'L.': [4870], 'second': [4873], 'operator': [4874], 'involved': [4876], '(lasB)': [4881], 'activation.': [4882], '181:': [4885], '6264–': [4886], '70.': [4887], 'Watanabe': [4893], 'Kawase': [4897], '(2004)': [4903], 'High': [4904], 'growing': [4905], 'biotype': [4910], 'essential': [4913], 'toxic': [4918], 'causing': [4920], 'systemic': [4921], 'diseases': [4922], 'humans.': [4924], '117–': [4928], '23.': [4929], 'Miller': [4937], 'Vance': [4939], 'R.E.,': [4940], 'Dziejman': [4941], 'Bassler': [4943], 'B.L.,': [4944], 'Mekalonas': [4945], 'Quorum-sensing': [4948], 'regulators': [4949], 'control': [4950], 'Vibio': [4955], '3129–': [4965], '31': [4971], 'Swift': [4972], 'Lynch': [4974], 'M.J.,': [4975], 'Fish': [4976], 'Kirke': [4978], 'D.F.,': [4979], 'Stewart': [4982], 'G.S.,': [4983], 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[5116], 'base': [5117], 'composition,': [5118], 'secondary': [5120], 'structure': [5121], 'giant': [5123], 'nuclear': [5124], 'acid.': [5126], 'Biochemistry': [5127], '12:': [5128], '2330–': [5129], 'Citing': [5135], 'Literature': [5136], 'Volume55,': [5137], 'Issue1January': [5138], '2011Pages': [5139], 'FiguresReferencesRelatedInformation': [5141]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1480500424', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-09T08:14:00.052918', 'created_date': '2016-06-24'}