Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2766838746', 'doi': 'https://doi.org/10.1007/s10529-017-2459-2', 'title': 'Characterization and mutation analysis of a halotolerant serine protease from a new isolate of Bacillus subtilis', 'display_name': 'Characterization and mutation analysis of a halotolerant serine protease from a new isolate of Bacillus subtilis', 'publication_year': 2017, 'publication_date': '2017-10-16', 'ids': {'openalex': 'https://openalex.org/W2766838746', 'doi': 'https://doi.org/10.1007/s10529-017-2459-2', 'mag': '2766838746', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29038928'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s10529-017-2459-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113993733', 'display_name': 'Biotechnology Letters', 'issn_l': '0141-5492', 'issn': ['0141-5492', '1573-6776'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101778628', 'display_name': 'Shinji Takenaka', 'orcid': 'https://orcid.org/0000-0002-7189-5927'}, 'institutions': [{'id': 'https://openalex.org/I65837984', 'display_name': 'Kobe University', 'ror': 'https://ror.org/03tgsfw79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I65837984']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Shinji Takenaka', 'raw_affiliation_strings': ['Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, 657-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, 657-8501, Japan', 'institution_ids': ['https://openalex.org/I65837984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022315016', 'display_name': 'Jyun Yoshinami', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I65837984', 'display_name': 'Kobe University', 'ror': 'https://ror.org/03tgsfw79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I65837984']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Jyun Yoshinami', 'raw_affiliation_strings': ['Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, 657-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, 657-8501, Japan', 'institution_ids': ['https://openalex.org/I65837984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035823968', 'display_name': 'Ampin Kuntiya', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I48076826', 'display_name': 'Chiang Mai University', 'ror': 'https://ror.org/05m2fqn25', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I48076826']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Ampin Kuntiya', 'raw_affiliation_strings': ['Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand', 'institution_ids': ['https://openalex.org/I48076826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071565197', 'display_name': 'Charin Techapun', 'orcid': 'https://orcid.org/0000-0002-3632-6470'}, 'institutions': [{'id': 'https://openalex.org/I48076826', 'display_name': 'Chiang Mai University', 'ror': 'https://ror.org/05m2fqn25', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I48076826']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Charin Techapun', 'raw_affiliation_strings': ['Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand', 'institution_ids': ['https://openalex.org/I48076826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012637170', 'display_name': 'Noppol Leksawasdi', 'orcid': 'https://orcid.org/0000-0002-4699-1351'}, 'institutions': [{'id': 'https://openalex.org/I48076826', 'display_name': 'Chiang Mai University', 'ror': 'https://ror.org/05m2fqn25', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I48076826']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Noppol Leksawasdi', 'raw_affiliation_strings': ['Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand', 'institution_ids': ['https://openalex.org/I48076826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062889293', 'display_name': 'Phisit Seesuriyachan', 'orcid': 'https://orcid.org/0000-0002-0898-5575'}, 'institutions': [{'id': 'https://openalex.org/I48076826', 'display_name': 'Chiang Mai University', 'ror': 'https://ror.org/05m2fqn25', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I48076826']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Phisit Seesuriyachan', 'raw_affiliation_strings': ['Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand', 'institution_ids': ['https://openalex.org/I48076826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076014708', 'display_name': 'Thanongsak Chaiyaso', 'orcid': 'https://orcid.org/0000-0003-2835-5578'}, 'institutions': [{'id': 'https://openalex.org/I48076826', 'display_name': 'Chiang Mai University', 'ror': 'https://ror.org/05m2fqn25', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I48076826']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Thanongsak Chaiyaso', 'raw_affiliation_strings': ['Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Bioprocess Research Cluster, The School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, Thailand', 'institution_ids': ['https://openalex.org/I48076826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077452433', 'display_name': 'Masanori Watanabe', 'orcid': 'https://orcid.org/0000-0003-4642-6675'}, 'institutions': [{'id': 'https://openalex.org/I112524849', 'display_name': 'Yamagata University', 'ror': 'https://ror.org/00xy44n04', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I112524849']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masanori Watanabe', 'raw_affiliation_strings': ['Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Yamagata, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Yamagata, Japan', 'institution_ids': ['https://openalex.org/I112524849']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109095627', 'display_name': 'Kosei Tanaka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I65837984', 'display_name': 'Kobe University', 'ror': 'https://ror.org/03tgsfw79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I65837984']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kosei Tanaka', 'raw_affiliation_strings': ['Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo, 657-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo, 657-8501, Japan', 'institution_ids': ['https://openalex.org/I65837984']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101609705', 'display_name': 'Ken‐ichi Yoshida', 'orcid': 'https://orcid.org/0000-0002-3383-4664'}, 'institutions': [{'id': 'https://openalex.org/I65837984', 'display_name': 'Kobe University', 'ror': 'https://ror.org/03tgsfw79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I65837984']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ken-ichi Yoshida', 'raw_affiliation_strings': ['Department of Science, Technology and Innovation, Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo, 657-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, Technology and Innovation, Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo, 657-8501, Japan', 'institution_ids': ['https://openalex.org/I65837984']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5101778628'], 'corresponding_institution_ids': ['https://openalex.org/I65837984'], 'apc_list': {'value': 2690, 'currency': 'EUR', 'value_usd': 3490, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.402, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.768995, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '40', 'issue': '1', 'first_page': '189', 'last_page': '196'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12996', 'display_name': 'Cancer Research and Treatments', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Enzyme Structure and Function', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/halotolerance', 'display_name': 'Halotolerance', 'score': 0.88698137}, {'id': 'https://openalex.org/keywords/bacillaceae', 'display_name': 'Bacillaceae', 'score': 0.70669055}], 'concepts': [{'id': 'https://openalex.org/C30992042', 'wikidata': 'https://www.wikidata.org/wiki/Q1529024', 'display_name': 'Halotolerance', 'level': 3, 'score': 0.88698137}, {'id': 'https://openalex.org/C2777272437', 'wikidata': 'https://www.wikidata.org/wiki/Q131238', 'display_name': 'Bacillus subtilis', 'level': 3, 'score': 0.8843303}, {'id': 'https://openalex.org/C2777932965', 'wikidata': 'https://www.wikidata.org/wiki/Q149098', 'display_name': 'Bacillaceae', 'level': 4, 'score': 0.70669055}, {'id': 'https://openalex.org/C2777807008', 'wikidata': 'https://www.wikidata.org/wiki/Q87324999', 'display_name': 'Serine protease', 'level': 4, 'score': 0.66696763}, {'id': 'https://openalex.org/C2778039104', 'wikidata': 'https://www.wikidata.org/wiki/Q149088', 'display_name': 'Bacillales', 'level': 4, 'score': 0.6317847}, {'id': 'https://openalex.org/C2776714187', 'wikidata': 'https://www.wikidata.org/wiki/Q212410', 'display_name': 'Protease', 'level': 3, 'score': 0.55160487}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.52483445}, {'id': 'https://openalex.org/C2776414213', 'wikidata': 'https://www.wikidata.org/wiki/Q183290', 'display_name': 'Serine', 'level': 3, 'score': 0.50735253}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.44189692}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42967683}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41230392}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.372131}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.338129}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.32049394}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.22567764}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.115816295}], 'mesh': [{'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D004252', 'descriptor_name': 'DNA Mutational Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012965', 'descriptor_name': 'Sodium Chloride', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019943', 'descriptor_name': 'Amino Acid Substitution', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007526', 'descriptor_name': 'Isoelectric Point', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016415', 'descriptor_name': 'Sequence Alignment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012965', 'descriptor_name': 'Sodium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s10529-017-2459-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113993733', 'display_name': 'Biotechnology Letters', 'issn_l': '0141-5492', 'issn': ['0141-5492', '1573-6776'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29038928', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1989036886', 'https://openalex.org/W1999050638', 'https://openalex.org/W2000575260', 'https://openalex.org/W2002452296', 'https://openalex.org/W2003718762', 'https://openalex.org/W2009680000', 'https://openalex.org/W2026431744', 'https://openalex.org/W2074417017', 'https://openalex.org/W2076894629', 'https://openalex.org/W2113666467', 'https://openalex.org/W2125007222', 'https://openalex.org/W2149039136', 'https://openalex.org/W2152407455', 'https://openalex.org/W2168019180', 'https://openalex.org/W2324713756', 'https://openalex.org/W2460733747', 'https://openalex.org/W2472745469', 'https://openalex.org/W2614999422'], 'related_works': ['https://openalex.org/W4376121869', 'https://openalex.org/W4309353051', 'https://openalex.org/W3217582246', 'https://openalex.org/W3048569867', 'https://openalex.org/W2766838746', 'https://openalex.org/W2235679260', 'https://openalex.org/W2162575606', 'https://openalex.org/W2122458212', 'https://openalex.org/W1972560754', 'https://openalex.org/W155910638'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2766838746', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-10T07:37:54.916486', 'created_date': '2017-11-10'}