Abstract: Viruses within the herpes-virus family are identified based primarily on morphology, as all herpes viruses contain a linear double-stranded DNA genome within an icosadeltahedral capsid, surrounded by a tegument and enclosed within a viral envelope. The tegument is a region between the capsid and envelope that has no distinct features in electron micrographs (ROIZMAN and FURLONG 1974). These viruses have both a lytic phase of their life cycle, resulting in the generation of infectious virus that may cause disease in the susceptible host, and a latent phase characterized by limited gene expression, during which no infectious virus can be isolated. Latent virus can be reactivated in response to a variety of stimuli, which may again result in disease manifestations (ROIZMAN 1993).
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 1
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