Title: Assessing Bioequivalence of Variabilities in $2{\times}2$ Crossover Design
Abstract:Several statistical procedures for assessment of bioequivalence of variabilities between two drug formulations in bioequivalence trials are reviewed and modified methods for assessing total variabilit...Several statistical procedures for assessment of bioequivalence of variabilities between two drug formulations in bioequivalence trials are reviewed and modified methods for assessing total variability are suggested. The problem of the current US FDA aggregate criterion for population bioequivalence and the necessity of disaggregate criterion are discussed with an illustrated example.Read More
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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