Publication Information

{'id': 'https://openalex.org/W69309170', 'doi': None, 'title': 'Heterogeneity in opsonic requirements of Staphylococcus epidermidis: relative importance of surface hydrophobicity, capsules and slime.', 'display_name': 'Heterogeneity in opsonic requirements of Staphylococcus epidermidis: relative importance of surface hydrophobicity, capsules and slime.', 'publication_year': 1989, 'publication_date': '1989-05-01', 'ids': {'openalex': 'https://openalex.org/W69309170', 'mag': '69309170', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2737697', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1385292'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2737697', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028646728', 'display_name': 'H van Bronswijk', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I887064364', 'display_name': 'University of Amsterdam', 'ror': 'https://ror.org/04dkp9463', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I887064364']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'H van Bronswijk', 'raw_affiliation_strings': ['Department of Medicine, Free University Hospital, Amsterdam, The Netherlands.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Free University Hospital, Amsterdam, The Netherlands.', 'institution_ids': ['https://openalex.org/I887064364']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112188174', 'display_name': 'Henri A. Verbrugh', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'H A Verbrugh', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087384580', 'display_name': 'H. C. J. M. Heezius', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'H C Heezius', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022848065', 'display_name': 'Nicole H. M. Renders', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'N H Renders', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108486727', 'display_name': 'A. Fleer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A Fleer', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017485109', 'display_name': 'Jan van der Meulen', 'orcid': 'https://orcid.org/0000-0002-9451-2335'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J van der Meulen', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113613129', 'display_name': 'P. L. Oe', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'P L Oe', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5004817782', 'display_name': 'J. Verhoef', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J Verhoef', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.116, 'has_fulltext': False, 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.547949, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '67', 'issue': '1', 'first_page': '81', 'last_page': '6'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13326', 'display_name': 'Biochemical and Structural Characterization', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13326', 'display_name': 'Biochemical and Structural Characterization', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 0.991, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/antibody-opsonization', 'display_name': 'Antibody opsonization', 'score': 0.985917}, {'id': 'https://openalex.org/keywords/coagulase', 'display_name': 'Coagulase', 'score': 0.43869644}], 'concepts': [{'id': 'https://openalex.org/C168507396', 'wikidata': 'https://www.wikidata.org/wiki/Q14859847', 'display_name': 'Antibody opsonization', 'level': 4, 'score': 0.985917}, {'id': 'https://openalex.org/C89372155', 'wikidata': 'https://www.wikidata.org/wiki/Q420107', 'display_name': 'Opsonin', 'level': 3, 'score': 0.9681598}, {'id': 'https://openalex.org/C160448771', 'wikidata': 'https://www.wikidata.org/wiki/Q184726', 'display_name': 'Phagocytosis', 'level': 2, 'score': 0.7874778}, {'id': 'https://openalex.org/C2777949923', 'wikidata': 'https://www.wikidata.org/wiki/Q131915', 'display_name': 'Staphylococcus epidermidis', 'level': 4, 'score': 0.75367117}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.7110415}, {'id': 'https://openalex.org/C2780199535', 'wikidata': 'https://www.wikidata.org/wiki/Q223102', 'display_name': 'Peritonitis', 'level': 2, 'score': 0.5086409}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.46468094}, {'id': 'https://openalex.org/C8408860', 'wikidata': 'https://www.wikidata.org/wiki/Q1755077', 'display_name': 'Coagulase', 'level': 5, 'score': 0.43869644}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.41430563}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37688065}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.37235677}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.3302212}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.32244536}, {'id': 'https://openalex.org/C2779288629', 'wikidata': 'https://www.wikidata.org/wiki/Q199695', 'display_name': 'Staphylococcus', 'level': 4, 'score': 0.31322998}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009895', 'descriptor_name': 'Opsonin Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000907', 'descriptor_name': 'Antibodies, Bacterial', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D000907', 'descriptor_name': 'Antibodies, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002473', 'descriptor_name': 'Cell Wall', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002473', 'descriptor_name': 'Cell Wall', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003165', 'descriptor_name': 'Complement System Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D003165', 'descriptor_name': 'Complement System Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009895', 'descriptor_name': 'Opsonin Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010587', 'descriptor_name': 'Phagocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': 'Q000145', 'qualifier_name': 'classification', 'is_major_topic': False}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2737697', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1790756950', 'https://openalex.org/W1827970128', 'https://openalex.org/W1909429339', 'https://openalex.org/W1953308998', 'https://openalex.org/W1968020208', 'https://openalex.org/W1990792235', 'https://openalex.org/W2026093238', 'https://openalex.org/W2036270217', 'https://openalex.org/W2040578679', 'https://openalex.org/W2054950768', 'https://openalex.org/W2062268621', 'https://openalex.org/W2069661600', 'https://openalex.org/W2091108803', 'https://openalex.org/W2115135671', 'https://openalex.org/W2131107336', 'https://openalex.org/W2144786743', 'https://openalex.org/W2168659270', 'https://openalex.org/W2169027034', 'https://openalex.org/W32115958', 'https://openalex.org/W87082738'], 'related_works': ['https://openalex.org/W69309170', 'https://openalex.org/W630997112', 'https://openalex.org/W2144786743', 'https://openalex.org/W2131107336', 'https://openalex.org/W2122728331', 'https://openalex.org/W2053062491', 'https://openalex.org/W2032812828', 'https://openalex.org/W2011145752', 'https://openalex.org/W1994729133', 'https://openalex.org/W1935527110'], 'abstract_inverted_index': {'The': [0, 19, 202], 'opsonic': [1, 48, 92, 166], 'requirements': [2, 49, 148], 'of': [3, 6, 94, 97, 119, 142, 176, 194, 204], '65': [4], 'strains': [5, 20, 133, 136, 160], 'Staphylococcus': [7], 'epidermidis': [8, 110, 121, 206], 'were': [9, 21, 77, 149], 'compared': [10, 73, 198], 'in': [11, 14, 47, 62, 114, 208, 213, 221], 'fresh': [12, 56, 75, 95, 178], 'and': [13, 36, 57, 68, 96, 128, 134, 163, 179], 'heated': [15, 59, 63, 98, 180, 195, 209], 'normal': [16], 'human': [17], 'serum.': [18, 60, 116], 'isolated': [22], 'from': [23, 169, 188], 'patients': [24], 'with': [25, 55, 58, 153], 'CAPD': [26, 189], 'peritonitis': [27, 190], '(n': [28, 33, 39], '=': [29, 34, 40, 101], '26),': [30], 'neonatal': [31], 'septicaemia': [32], '24)': [35], 'nasal': [37, 170], 'cultures': [38, 171], '15).': [41], 'A': [42], 'wide': [43], 'variation': [44], 'was': [45, 87], 'observed': [46], 'between': [50, 89], 'the': [51, 90, 159], 'different': [52], 'strains,': [53], 'both': [54, 177], 'Opsonization': [61], 'serum': [64, 99, 143, 181, 196, 210], 'proceeded': [65], 'less': [66, 104], 'efficiently': [67], 'higher': [69, 140, 174, 192], 'concentrations': [70, 93, 141, 175, 193], '(mean': [71], 'three-fold': [72], 'to': [74, 144, 182, 199], 'serum)': [76], 'needed': [78], 'for': [79], 'adequate': [80], 'phagocytosis.': [81], 'However,': [82], 'a': [83, 222], 'highly': [84, 150], 'significant': [85], 'correlation': [86], 'found': [88], 'minimal': [91], '(r': [100], '0.84,': [102], 'P': [103], 'than': [105], '0.0005).': [106], 'In': [107], 'addition,': [108], 'S.': [109, 120, 205], 'can': [111, 122], 'become': [112, 145, 183], 'opsonized': [113], 'agammaglobulinaemic': [115], 'Thus,': [117], 'opsonization': [118], 'be': [123], 'mediated': [124], 'by': [125, 129], 'antibodies': [126], 'alone': [127], 'complement': [130], 'alone.': [131], 'Slime-producing': [132], 'encapsulated': [135], 'did': [137, 218], 'not': [138, 219], 'require': [139], 'opsonized.': [146], 'Opsonic': [147], 'significantly': [151, 173], 'correlated': [152], 'surface': [154], 'hydrophobicity.': [155], 'Enzymatic': [156], 'treatment': [157], 'rendered': [158], 'more': [161], 'hydrophilic': [162], 'decreased': [164], 'their': [165], 'requirements.': [167], 'Isolates': [168], 'required': [172, 191], 'adequately': [184], 'phagocytozed,': [185], 'whereas': [186], 'isolates': [187], 'only': [197], 'blood': [200], 'isolates.': [201], 'uptake': [203], 'preopsonized': [207], 'as': [211], 'determined': [212], 'our': [214], 'direct': [215], 'phagocytosis': [216], 'assay': [217], 'result': [220], 'comparable': [223], 'chemiluminescence': [224], 'response.': [225]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W69309170', 'counts_by_year': [], 'updated_date': '2024-12-27T12:09:06.333078', 'created_date': '2016-06-24'}