Publication Information

{'id': 'https://openalex.org/W628846560', 'doi': None, 'title': 'Therapeutic oligonucleotides : transcriptional and translational strategies for silencing gene expression', 'display_name': 'Therapeutic oligonucleotides : transcriptional and translational strategies for silencing gene expression', 'publication_year': 2005, 'publication_date': '2005-01-01', 'ids': {'openalex': 'https://openalex.org/W628846560', 'mag': '628846560'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://ci.nii.ac.jp/ncid/BA76294999', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463658', 'display_name': 'New York Academy of Sciences eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'book', 'type_crossref': 'book', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111545178', 'display_name': 'Yoon S. Cho‐Chung', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yoon S. Cho-Chung', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109984754', 'display_name': 'Alan M. Gewirtz', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A. M. Gewirtz', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109357631', 'display_name': 'Cy A. Stein', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Cy A. Stein', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.077, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.287273, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 68, 'max': 71}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13937', 'display_name': 'Genetics, Bioinformatics, and Biomedical Research', 'score': 0.9064, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13937', 'display_name': 'Genetics, Bioinformatics, and Biomedical Research', 'score': 0.9064, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12929', 'display_name': 'Animal Genetics and Reproduction', 'score': 0.9046, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.8310534}, {'id': 'https://openalex.org/C129312508', 'wikidata': 'https://www.wikidata.org/wiki/Q133686', 'display_name': 'Oligonucleotide', 'level': 3, 'score': 0.6138724}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.57213247}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.52918214}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44053295}, {'id': 'https://openalex.org/C24107716', 'wikidata': 'https://www.wikidata.org/wiki/Q123619', 'display_name': 'Nucleic acid', 'level': 2, 'score': 0.43041947}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.4227243}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3970077}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.38139373}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.2939204}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1770905}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://ci.nii.ac.jp/ncid/BA76294999', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463658', 'display_name': 'New York Academy of Sciences eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.64, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W642328518', 'https://openalex.org/W623861257', 'https://openalex.org/W615553497', 'https://openalex.org/W582841148', 'https://openalex.org/W572339647', 'https://openalex.org/W570606785', 'https://openalex.org/W566122923', 'https://openalex.org/W565483693', 'https://openalex.org/W408313342', 'https://openalex.org/W3001004095', 'https://openalex.org/W2996166713', 'https://openalex.org/W2950859937', 'https://openalex.org/W2338343138', 'https://openalex.org/W2189599180', 'https://openalex.org/W212351281', 'https://openalex.org/W1604073273', 'https://openalex.org/W1552545829', 'https://openalex.org/W1550146907', 'https://openalex.org/W1478604736', 'https://openalex.org/W1246092528'], 'abstract_inverted_index': {'Introduction:': [0], 'Y': [1], 'S': [2], 'Cho-Chung,': [3, 450], 'Alan': [4], 'M.': [5, 208, 269, 320, 338, 342], 'Gewirtz,': [6], 'and': [7, 32, 36, 41, 57, 67, 72, 77, 92, 114, 122, 148, 184, 193, 218, 232, 249, 280, 325, 340, 395, 429, 438, 459, 469, 491, 501, 524, 555, 588, 606], 'Cy': [8], 'A.': [9, 317, 576, 590], 'Stein.': [10, 558], 'Part': [11, 64, 118, 188, 252, 344, 463, 527], 'I:': [12], 'Kill': [13], 'the': [14, 25, 439], 'Messenger:': [15], 'Gene': [16, 442], 'Silencing': [17, 126, 196, 255, 479], 'by': [18, 53, 256, 300, 358, 467, 539], 'Nucleic': [19, 55, 257, 529], 'Acid': [20, 258, 530], 'Molecules.': [21, 259], '1.': [22], 'Knock-down': [23], 'of': [24, 47, 79, 125, 151, 166, 192, 201, 238, 263, 306, 354, 400, 436, 441, 496, 506, 537], 'Cytoprotective': [26], 'Gene,': [27], 'Clusterin,': [28], 'to': [29, 195, 224, 240, 499], 'Enhance': [30], 'Hormone': [31], 'Chemosensitivity': [33, 465], 'in': [34, 50, 107, 242, 367, 407, 541, 569, 600], 'Prostate': [35], 'Other': [37, 502], 'Cancers:': [38], 'Martin': [39], 'Gleave': [40], 'Kim': [42], 'N.': [43], 'Chi.': [44], '2.': [45], 'Recognition': [46], 'Chromosomal': [48], 'DNA': [49, 81, 297], 'Human': [51, 368, 533], 'Cells': [52], 'Peptide': [54], 'Acids': [56], 'Small': [58], 'Duplex': [59], 'RNAs:': [60], 'David': [61], 'R.': [62, 513], 'Corey.': [63], 'II:': [65], 'Antisense': [66, 154, 468, 498, 599], 'siRNA:': [68], 'Chemistry,': [69], 'Sequence': [70], 'Specificity,': [71], 'Target': [73], 'Validation.': [74], '3.': [75], 'Design': [76], 'Development': [78, 237, 262, 505], 'Thermolytic': [80], 'Oligonucleotide': [82], 'Prodrugs:': [83], 'Andrzej': [84], 'Grajkowski,': [85], 'Joao': [86], 'Pedras-Vasconcelos,': [87], 'Cristina': [88], 'Ausin,': [89], 'Daniela': [90], 'Verthelyi,': [91], 'Serge': [93], 'L.': [94], 'Beaucage.': [95], '4.': [96], 'Rationally': [97], 'Targeted,': [98], 'Conformationally': [99], 'Constrained,': [100], 'Oxetane-Modified': [101], 'Oligonucleotides': [102, 202, 302], 'Demonstrate': [103], 'Efficient': [104], 'Gene-Silencing': [105], 'Activity': [106], 'a': [108, 304], 'Cellular': [109, 121], 'System:': [110], 'J': [111], 'B': [112], 'Opalinska': [113], 'A': [115, 159, 178, 287, 557, 561, 597], 'M': [116], 'Gewirtz.': [117], 'III:': [119], 'Delivery': [120, 165, 309], 'Phenotype': [123], 'Effect': [124], 'Agents:.': [127], '5.': [128], 'In': [129], 'Vivo': [130], 'Potentialities': [131], 'Andrei': [132], 'Maksimenko,': [133], 'Valerie': [134], 'Polard,': [135], 'Marie': [136], 'Villemeur,': [137], 'Hind': [138], 'Elhamess,': [139], 'Patrick': [140], 'Couvreur,': [141], 'Jean-Remi': [142], 'Bertrand,': [143], 'Malam': [144], 'Aboubakar,': [145], 'Marina': [146], 'Gottikh,': [147], 'Claude': [149], 'Malvy': [150], 'EWS-Fli-1': [152], 'Targeted': [153, 330], 'Oligonucleotides-Nanospheres': [155], 'Complexes:.': [156], '6.': [157], 'Endo-Porter:': [158], 'Novel': [160, 472], 'Reagent': [161], 'for': [162, 290, 403, 532, 564], 'Safe,': [163], 'Effective': [164], 'Substances': [167], 'into': [168, 310], 'Cells:': [169, 244, 370, 543], 'James': [170, 575], 'E.': [171, 422, 573], 'Summerton.': [172], '7.': [173], 'Tumor': [174], 'Reversion:': [175], 'Protein': [176, 595], 'Kinase': [177, 596], 'Isozyme': [179], 'Switching:': [180], 'Yoon': [181, 448, 607], 'S.': [182, 278, 449, 608], 'Cho-Chung': [183, 609], 'Maria': [185, 603], 'V.': [186, 314, 604], 'Nesterova.': [187], 'IV:': [189], 'Immune': [190], 'Modulation': [191], 'Resistance': [194, 239], 'Agents.': [197], '8.': [198], 'Therapeutic': [199], 'Potential': [200], 'Expressing': [203], 'Immunosuppressive': [204], 'TTAGGG': [205], 'Motifs:': [206], 'Dennis': [207], 'Klinman,': [209], 'Ihsan': [210], 'Gursel,': [211], 'Sven': [212], 'Klaschik,': [213], 'Li': [214], 'Dong,': [215], 'Debbie': [216], 'Currie,': [217], 'Hidekazu': [219], 'Shirota.': [220], '9.': [221], 'Breaking': [222], 'Tolerance': [223], 'Tumors': [225], 'with': [226, 594], 'Dendritic': [227], 'Cell-Based': [228], 'Immunotherapy:': [229], 'Ines': [230], 'Mende': [231], 'Edgar': [233], 'G.': [234, 323, 461], 'Engleman.': [235], '10.': [236], 'RNAi': [241], 'Mammalian': [243], 'Zhi-Ming': [245], 'Zheng,': [246], 'Shuang': [247], 'Tang,': [248], 'Mingfang': [250], 'Tao.': [251], 'V:': [253], 'Transcription': [254, 284, 364], '11.': [260], 'The': [261], 'Bioactive': [264], 'Triple': [265, 334], 'Helix-Forming': [266], 'Oligonucleotides:': [267], 'Michael': [268, 293, 393], 'Seidman,': [270], 'Nitin': [271], 'Puri,': [272], 'Alokes': [273], 'Majumdar,': [274], 'Bernard': [275], 'Cuenoud,': [276], 'Paul': [277, 553], 'Miller,': [279, 554], 'Rowshon': [281], 'Alam.': [282], '12.': [283], 'Factor': [285, 365], 'Decoys:': [286], 'New': [288], 'Model': [289], 'Disease': [291], 'Intervention:': [292], 'J.': [294], 'Mann.': [295], '13.': [296], 'Damage': [298], 'Produced': [299], '125I-Triplex-Forming': [301], 'as': [303], 'Measure': [305], 'Their': [307], 'Succesful': [308], 'Cell': [311], 'Nuclei:': [312], 'Irina': [313], 'Panyutin,': [315, 324], 'Olga': [316], 'Sedelnikova,': [318], 'William': [319], 'Bonner,': [321], 'Igor': [322], 'Ronald': [326], 'D.': [327], 'Neumann.': [328], '14.': [329], 'Genome': [331], 'Modification': [332], 'via': [333], 'Helix': [335], 'Formation:': [336], 'Jennifer': [337], 'Kalish': [339], 'Peter': [341, 515, 589], 'Glazer.': [343], 'VI:': [345], 'Functional': [346], 'Genomics-Antisense/RNAi.': [347], '15.': [348], 'Promoter': [349], 'Array': [350], 'Studies': [351], 'Identify': [352], 'Cohorts': [353], 'Genes': [355], 'Directly': [356], 'Regulated': [357], 'Methylation,': [359], 'Copy': [360], 'Number': [361], 'Change,': [362], 'or': [363], 'Binding': [366], 'Cancer': [369, 500, 570], 'Yipeng': [371], 'Wang,': [372, 484], 'Jun': [373], 'Hayakawa,': [374], 'Fred': [375], 'Long,': [376], 'Qiuju': [377], 'Yu,': [378], 'Ann': [379], 'H.': [380], 'Cho,': [381], 'Gaelle': [382], 'Rondeau,': [383], 'John': [384, 521], 'Welsh,': [385], 'Shalu': [386], 'Mittal,': [387], 'Ian': [388], 'De': [389], 'Belle,': [390], 'Eileen': [391], 'Adamson,': [392], 'Mcclelland,': [394], 'Dan': [396], 'Mercola.': [397], '16.': [398], 'Application': [399, 495], 'Expression': [401], 'Genomics': [402], 'Predicting': [404], 'Treatment': [405], 'Response': [406], 'Cancer:': [408], 'Khew-Voon': [409], 'Chin,': [410], 'Leah': [411], 'Alabanza,': [412], 'Kazuyuki': [413], 'Fujii,': [414], 'Kazuya': [415], 'Kudoh,': [416], 'Tsunekazu': [417], 'Kita,': [418], 'Yoshihiro': [419], 'Kikuchi,': [420], 'Zachariah': [421], 'Selvanayagam,': [423], 'Yick': [424], 'Fu': [425], 'Wong,': [426], 'Yong': [427], 'Lin,': [428], 'Wei': [430], 'Chung': [431], 'Shih.': [432], '17.': [433], 'Stability': [434], 'Regulation': [435], 'mRNA': [437], 'Control': [440], 'Expression:': [443], 'Chris': [444], 'Cheadle,': [445], 'Jinshui': [446], 'Fan,': [447], 'Thomas': [451], 'Werner,': [452], 'Jill': [453], 'Ray,': [454], 'Lana': [455], 'Do,': [456], 'Myriam': [457], 'Gorospe,': [458], 'Kevin': [460], 'Becker.': [462], 'VII:': [464], 'Enhancement': [466], 'RNAi.': [470], '18.': [471], 'MDM2': [473], 'p53-Independent': [474], 'Functions': [475], 'Identified': [476], 'through': [477], 'RNA': [478], 'Technologies:': [480], 'Zhuo': [481], 'Zhang,': [482], 'Hui': [483], 'Mao': [485], 'Li,': [486], 'Elizabeth': [487], 'Rayburn,': [488], 'Sudhir': [489, 519], 'Agrawal,': [490, 520], 'Ruiwen': [492], 'Zhang.': [493], '19.': [494], 'XIAP': [497], 'Proliferative': [503], 'Disorders:': [504], 'AEG35156/': [507], 'GEM(r)640:': [508], 'Eric': [509], 'C.': [510, 547, 583], 'Lacasse,': [511], 'Ekambar': [512], 'Kandimalla,': [514], 'Winocour,': [516], 'Tim': [517], 'Sullivan,': [518], 'W.': [522], 'Gillard,': [523], 'Jon': [525], 'Durkin.': [526], 'VIII:': [528], 'Therapeutics': [531], 'Diseases.': [534], '20.': [535], 'Induction': [536], 'Apoptosis': [538], 'G3139': [540], 'Melanoma': [542], 'Luba': [544], 'Benimetskaya,': [545], 'Johnathan': [546], 'Lai,': [548], 'Anastasia': [549], 'Khvorova,': [550], 'Sijian': [551], 'Wu,': [552], 'C': [556], '21.': [559], 'Zebularine:': [560], 'Unique': [562], 'Molecule': [563], 'an': [565], 'Epigenetically': [566], 'Based': [567], 'Strategy': [568], 'Chemotherapy:': [571], 'Victor': [572], 'Marquez,': [574], 'Kelley,': [577], 'Riad': [578], 'Agbaria,': [579], 'Tisipi': [580], 'Ben-Kasus,': [581], 'Jonathan': [582], 'Cheng,': [584], 'Christine': [585], 'B.': [586], 'Yoo,': [587], 'Jones.': [591], '22.': [592], 'Chemoprevention': [593], 'RI': [598], 'DMBA-Mammary': [601], 'Carcinogenesis:': [602], 'Nesterova': [605]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W628846560', 'counts_by_year': [{'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-12-14T16:04:38.031973', 'created_date': '2016-06-24'}