Title: Diagnosis and Therapy of Porphyrias and Lead Intoxication: International Symposium Clinical Biochemistry
Abstract: Session I Pathobiochemistry of Heme Metabolism.- Regulation of Heme Biosynthesis in Hepatic and Erythroid Cells: A Brief Introduction to the Pathobiochemistry of Human Porphyrias.- Differential Patterns of Heme and Porphyrin Biosynthesis in Liver and Kidney: Metal Ion Blockade of ?-Aminolevulinate Synthase Introduction by Porphyrinogenic Agents.- The Regulatory Function of the Mitochondrial Inner Membrane in the Overall Ferrochelatase Reaction.- Permissive Effects of Hormone on the Induction of ?-Aminolevulinic Acid Synthase (ALA-S) in Cultured Chick-Embryo Liver Cells.- Session II Pathogenesis and Differential Diagnosis of Acute Hepatic Porphyrias.- Biochemical and Clinical Transitions Between the Hereditary Hepatic Porphyrias: New Concepts.- A New Approach to Porphyrias.- The Clinical Chemistry of Variegate Porphyria With Special Reference to the Identification of a New Plasma-Marker Porphyrin.- Expression of the Gene Defects of Acute Intermittent Porphyria (AIP) and Erythropoietic Protoporphyria (EPP) in Mitogen-Stimulated Lymphocytes.- Uroporphyrinogen-Synthase (URO-S) in Erythrocytes in Acute Intermittent Porphyria (AIP).- Hereditary Coproporphyria: Demonstration of a Genetic Defect in Coproporphyrinogen Metabolism.- Session III Clinical Course and Therapy of Acute Hepatic Porphyrias.- A Case of Acute Intermittent Porphyria, Relapsing Acute Pancreatitis, and Unconjugated Hyperbilirubinemia (Gilbert's Syndrome).- Acute Intermittent Porphyria: EEG Changes and Their Relationship to the Biochemical Manifestation.- Family Studies of Patients With Acute Intermittent Porphyria (AIP): Neurological, Biochemical, and Genetic Investigations.- The Effect of Hematin in Inducible Hepatic Porphyria.- Therapy of Acute Intermittent Porphyria With Ovulation Inhibitors in Women.- Session IV Pathogenesis, Clinical Biochemistry, and Treatment of Chronic Hepatic Porphyrias.- Clinical Observation, Diagnostics, and Therapy for Symptomatic and Hereditary Porphyria Cutanea Tarda.- Uroporphyrinogen Decarboxylase (URO-D) Defect in Erythrocytes in Chronic Hepatic Porphyrias.- The Problem of Possible Etiological Factors in the Origin and Development of PCT.- Incidence of Porphyria in Slovenia.- Chronic Hepatic Porphyrias and the Role of Iron in These Disorders.- Chloroquine in the Treatment of Porphyria Cutanea Tarda.- Chloroquine Treatment of Porphyria Cutanea Tarda.- Clinical Importance of Suburoporphyrins.- Current Diagnostic Problems in the Cutaneous Porphyrias in Infancy. Presentation of Unusual Cases.- Session V Porphyria and Environment.- Influence of Environmental Factors on Porphyrin Metabolism.- Porphyrinogenic Action of Polyhalogenated Aromatic Compounds, With Special Reference to Porphyria and Environmental Impact.- Lead Poisoning Attributable to Automobile Traffic.- Neoplasms and Metabolic Disturbances of Porphyrins in Rats With Chronic Experimental Lead Poisoning.- Session VI Diagnosis of Lead Intoxication.- Time Course and Compartment Relations of Heme-Synthesis Disturbances Induced by Inorganic Lead Compounds in Humans.- Urinary Porphyrin Profiles in Acute Lead Poisoning: Relation to Differentiation From Acute Intermittent Porphyria.- Determination of Lead and Cadmium in Whole Blood by Electrothermal Atomic Absorption Spectroscopy.- Biochemical Behavior of ?-Aminolevulinic Acid Dehydratase During Chronic Oral Lead Poisoning in Sheep.- Diagnostic Criteria of Increased Lead Absorption in Occupational Medicine.- Analysis of the Diagnostically Relevant Heme Precursors (5-Aminolevulinic Acid, Coproporphyrin, and Protoporphyrin) in Lead Poisoning by Use of Thin-Layer Chromatography.- Comparison of Fluorometric Micromethods for Analyzing Erythrocytic Porphyrins (EP).- Session VII Therapy of Lead Intoxication.- Therapy for Lead Poisoning.- Subclinical Effects of a Ubiquitous Poison: Lead.- Correlations Between Chronic Exposure to Lead and Excretion of Heme Precursors in Ceramics Industry Workers.- Session VIII Porphyria and Tumors.- Modification of Radiosensitivity by Porphyrins: Studies of Tumors and Other Systems.- Meso-Tetra (P-Sulfophenyl) Porphine as a Potential Tumor-Localizing Agent.- Frequency of Occurrence of Hepatocellular Carcinoma in Patients With Porphyria Cutanea Tarda in Long-term Follow-up.- Organ Porphyrins in Human Circulatory Disorders and Neoplastic Disease.- Session IX Erythropoietic Protoporphyria.- Characterization of the Defect in Heme Metabolism in Patients With Erythropoietic Protoporphyria.- Biochemical and Morphologic Changes in Early Phases of Experimental Protoporphyria.- Hereditary Bovine Protoporphyria, a Total Body Deficiency of Ferrochelatase: Some Basic Distinctions From Hypochromic Anemias.- Treatment of Erythropoietic Porphyrias.- Session X Porphyrin, Heme, and Iron Transport.- Interaction of Porphyrins With Proteins.- Hemopexin and Albumin Metabolism in Porphyria Cutanea Tarda.- Photodynamic Modification of Erythrocyte Membrane Proteins Induced by Protoporphyrin.- New Aspects of Hematin Excretion in Rats.- Hematin Therapy in Acute Porphyria and Observations on Hemopexin.- Addendum, Memorandum Lectures.- Das Wirken Hans Fischers fur die Porphyrinforschung.- Thudichum und der Purpur.
Publication Year: 1978
Publication Date: 1978-09-01
Language: en
Type: book
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Cited By Count: 5
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