Title: [Proteins regulating neurotransmitter release of synaptic vesicles at nerve terminals].
Abstract:Neurotransmitter release of synaptic vesicle at nerve terminals is a complicated and elaborately regulated process, involving a cascade of protein-protein interactions. The SNARE core complex consisti...Neurotransmitter release of synaptic vesicle at nerve terminals is a complicated and elaborately regulated process, involving a cascade of protein-protein interactions. The SNARE core complex consisting of synaptobrevin/VAMP (a synaptic-terminal protein), syntaxin and SNAP-25 (synaptic membrane-associated proteins), acts as the membrane fusion machinery and plays essential roles in synaptic vesicle exocytosis. This review will discuss proteins with potential roles in synaptic vesicle exocytosis by regulating assembly, disassembly and the function of SNARE complex, and sum up the molecular model of vesicle exocytosis.Read More
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 1
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