Publication Information

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Honda', 'raw_affiliation_strings': ["Tokyo Women's Medical University Hospital, Institute of Rheumatology, Tokyo, Japan", "Tokyo Women's Medical University School of Medicine, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan"], 'affiliations': [{'raw_affiliation_string': "Tokyo Women's Medical University School of Medicine, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210136522']}, {'raw_affiliation_string': "Tokyo Women's Medical University Hospital, Institute of Rheumatology, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210098959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027098647', 'display_name': 'Keisuke Ikari', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210136522', 'display_name': "Tokyo Women's Medical University", 'ror': 'https://ror.org/03kjjhe36', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210136522']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'K. Ikari', 'raw_affiliation_strings': ["Tokyo Women's Medical University School of Medicine, Department of Orthopedic Surgery, Tokyo, Japan", "Tokyo Women's Medical University School of Medicine, Division of Multidisciplinary Management of Rheumatic Diseases, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan"], 'affiliations': [{'raw_affiliation_string': "Tokyo Women's Medical University School of Medicine, Department of Orthopedic Surgery, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210136522']}, {'raw_affiliation_string': "Tokyo Women's Medical University School of Medicine, Division of Multidisciplinary Management of Rheumatic Diseases, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210136522']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030809485', 'display_name': 'Eiichi Tanaka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098959', 'display_name': "Tokyo Women's Medical University Hospital", 'ror': 'https://ror.org/014knbk35', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210098959']}, {'id': 'https://openalex.org/I4210136522', 'display_name': "Tokyo Women's Medical University", 'ror': 'https://ror.org/03kjjhe36', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210136522']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'E. Tanaka', 'raw_affiliation_strings': ["Tokyo Women's Medical University Hospital, Institute of Rheumatology, Tokyo, Japan", "Tokyo Women's Medical University School of Medicine, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan"], 'affiliations': [{'raw_affiliation_string': "Tokyo Women's Medical University Hospital, Institute of Rheumatology, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210098959']}, {'raw_affiliation_string': "Tokyo Women's Medical University School of Medicine, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan", 'institution_ids': ['https://openalex.org/I4210136522']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5085365180', 'display_name': 'M. 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'https://openalex.org/W4285208911', 'https://openalex.org/W4213079790', 'https://openalex.org/W3215138031', 'https://openalex.org/W3082895349', 'https://openalex.org/W3009238340', 'https://openalex.org/W2731899572', 'https://openalex.org/W2248239756'], 'abstract_inverted_index': {'<h3>Background:</h3>': [0], 'Cardiovascular': [1, 330], 'diseases': [2], 'account': [3], 'for': [4, 41, 105, 126, 293, 314, 334, 433, 442, 466, 497, 505, 511, 546], 'about': [5], '15%': [6], 'of': [7, 10, 23, 57, 73, 142, 167, 202, 236, 240, 251, 276, 355, 398, 406, 422, 523, 614], 'the': [8, 42, 55, 71, 76, 102, 123, 140, 165, 187, 193, 200, 257, 274, 302, 321, 347, 353, 361, 366, 369, 375, 379, 383, 391, 427, 430, 461, 488, 492, 514, 521, 558, 605, 609], 'causes': [9], 'death': [11], 'in': [12, 29, 70, 84, 128, 139, 186, 260, 341, 374, 382, 426, 548], 'patients': [13, 30, 50, 106, 129, 185, 337, 400, 413, 424, 549], 'with': [14, 31, 51, 107, 130, 136, 148, 271, 285, 352, 402, 453, 474, 550, 608], 'rheumatoid': [15], 'arthritis': [16], '(RA)': [17], '[1],': [18], 'and': [19, 21, 147, 150, 197, 220, 283, 305, 408, 441, 507, 531], 'prediction': [20, 38, 61, 88, 120, 562], 'prevention': [22], 'major': [24], 'adverse': [25], 'cardiovascular': [26, 36, 86, 118, 560], 'events': [27], '(MACE)': [28], 'RA': [32, 52, 144, 335, 551], 'is': [33, 63, 552], 'important.': [34], 'Existing': [35], 'event': [37, 87], 'scores': [39, 89, 99, 121, 477], 'developed': [40], 'general': [43], 'population': [44], 'underestimate': [45], 'risk': [46, 119, 458, 561], 'when': [47], 'applied': [48], 'to': [49, 90, 157, 205, 296, 345, 357, 360, 599, 603], '[2].': [53], 'Therefore,': [54], 'development': [56], 'a': [58, 228, 234, 266, 312, 342, 396, 403], 'more': [59], 'accurate': [60], 'algorithm': [62], 'urgently': [64], 'needed.': [65], 'Despite': [66], 'its': [67], 'widespread': [68], 'use': [69], 'assessment': [72], 'heart': [74, 171], 'disease,': [75], 'cardiothoracic': [77], 'ratio': [78, 344], '(CTR)': [79], 'has': [80], 'not': [81], 'been': [82], 'used': [83], 'any': [85], 'date.': [91], 'Incorporating': [92], 'radiograph': [93, 114, 152, 243, 278, 462], 'indices': [94, 115, 279, 463], 'like': [95, 598], 'CTR': [96, 219, 297, 315, 434, 450, 476, 499, 518, 556], 'into': [97, 116, 317, 557], 'existing': [98, 117, 318, 559], 'may': [100], 'alter': [101], 'predictive': [103, 124, 380, 544], 'score': [104, 249, 313, 362], 'RA.': [108, 131], '<h3>Objectives:</h3>': [109], 'To': [110, 310], 'investigate': [111], 'whether': [112], 'incorporating': [113, 555], 'enhances': [122], 'accuracy': [125, 381, 522, 545], 'MACE': [127, 286, 294, 454, 547], '<h3>Methods:</h3>': [132], 'Patients': [133, 473], 'aged': [134], '≥20': [135], 'RA,': [137], 'enrolled': [138], 'Institute': [141, 239], 'Rheumatology': [143], '(IORRA)': [145], 'cohort,': [146, 351, 494, 516], 'chest': [149, 242, 420], 'hand': [151, 252], 'data': [153], 'from': [154, 368], 'April': [155], '2000': [156], 'September': [158, 213], '2022': [159], 'were': [160, 225, 287, 338, 501], 'included.': [161], 'MACE,': [162, 203], 'defined': [163], 'as': [164, 455], 'occurrence': [166, 201], 'myocardial': [168], 'infarction': [169], '(MI),': [170], 'failure,': [172], 'stroke,': [173], 'or': [174, 177, 212, 328, 349], 'cardiovascular-related': [175], 'hospitalization': [176], 'death,': [178], 'was': [179, 254, 299, 386, 435, 451], 'captured': [180], 'by': [181, 184, 301, 307, 364, 554], 'self-reported': [182], 'items': [183], 'IORRA': [188, 428, 610], 'database.': [189], 'Observations': [190], 'began': [191], 'at': [192, 199], 'earliest': [194], 'radiographic': [195], 'date': [196], 'censored': [198], 'loss': [204], 'follow-up,': [206], '10': [207], 'years': [208], 'after': [209, 464], 'observation': [210], 'initiation,': [211], '2023,': [214], 'whichever': [215], 'came': [216], 'first.': [217], 'The': [218, 245, 289, 543, 595], 'tracheal': [221], 'bifurcation': [222], 'angle': [223], '(TBA)': [224], 'extracted': [226, 255], 'using': [227, 256, 365, 388, 491], 'heatmap': [229], 'regression': [230, 269, 372, 489], 'model': [231, 270, 373], 'trained': [232], 'on': [233, 419, 487], 'dataset': [235], '1,400': [237], 'National': [238], 'Health': [241], 'images.': [244], 'Sharp/van': [246], 'der': [247], 'Heijde': [248], '(SHS)': [250], 'radiographs': [253, 421], 'method': [258, 304], 'reported': [259], 'our': [261], 'previous': [262], 'study': [263], '[3].': [264], 'Using': [265], 'time-dependent': [267], 'Cox': [268, 371], 'relevant': [272], 'covariates,': [273], 'associations': [275], 'these': [277], '(i.e.,': [280], 'CTR,': [281], 'TBA,': [282], 'SHS)': [284], 'assessed.': [288], 'event-free': [290], 'survival': [291, 481], 'rate': [292], 'according': [295], 'tertile': [298, 316, 500], 'described': [300], 'Kaplan-Meier': [303], 'compared': [306], 'log-rank': [308], 'test.': [309], 'incorporate': [311], 'scores,': [319], 'namely': [320], 'modified': [322], 'Systematic': [323], 'Coronary': [324], 'Risk': [325, 331], 'Evaluation': [326], '(mSCORE)': [327], 'Expanded': [329], 'Prediction': [332], 'Score': [333], '(ERS-RA),': [336], 'randomly': [339], 'assigned': [340], '1:1': [343], 'either': [346], 'Derivation': [348, 376, 493], 'Validation': [350, 384, 515], 'number': [354], 'points': [356], 'be': [358], 'added': [359], 'determined': [363], 'coefficient': [367], 'Penalized': [370], 'cohort.': [377], 'Subsequently,': [378], 'cohort': [385, 611], 'assessed': [387], 'area': [389], 'under': [390], 'curve': [392], '(AUC).': [393], '<h3>Results:</h3>': [394], 'Of': [395], 'total': [397], '3369': [399], 'selected,': [401], 'mean': [404], 'age': [405], '58.4': [407], '87.0%': [409], 'being': [410], 'female,': [411], '314': [412], 'experienced': [414], 'MACE.': [415], 'In': [416, 513], 'tests': [417], 'conducted': [418], '400': [423], 'registered': [425], 'database,': [429], 'average': [431], 'error': [432], '0.025': [436], '(standard': [437], 'deviation': [438], '[SD]': [439], '±0.9%),': [440], 'TBA': [443], '−2.4': [444], 'degrees': [445], '(SD': [446], '±6.8': [447], 'degrees).': [448], 'Only': [449], 'associated': [452], 'an': [456], 'independent': [457], 'factor': [459], 'among': [460], 'adjusting': [465], 'covariates': [467], '(CTR,': [468], 'p': [469, 529, 537], '&lt;0.0001)': [470], '(Table': [471], '1).': [472], 'higher': [475], 'had': [478], 'lower': [479], 'MACE-free': [480], 'rates': [482], '(P&lt;0.0001)': [483], '(Figure': [484, 540], '1A).': [485], 'Based': [486], 'analysis': [490], 'additive': [495], 'percentages': [496], 'each': [498], '+0,': [502, 508], '+0.3,': [503], '+2.6': [504], 'mSCORE,': [506], '+1.0,': [509], '+8.7': [510], 'ERS-RA.': [512], 'including': [517], 'significantly': [519], 'improved': [520], 'mSCORE': [524], '(AUC': [525, 533], '0.685': [526], 'vs.': [527, 535], '0.713;': [528], '=0.006)': [530], 'ERS-RA': [532], '0.675': [534], '0.714;': [536], '=': [538], '0.002)': [539], '1B).': [541], '<h3>Conclusion:</h3>': [542], 'enhanced': [553], 'scores.': [563], '<h3>REFERENCES:</h3>': [564], '[1]': [565], 'Nakajima': [566], 'A,': [567], 'et': [568, 579, 588], 'al.': [569, 580, 589], 'Scand': [570], 'J': [571], 'Rheumatol.': [572], '2010;': [573], '39:': [574], '360-367.': [575], '[2]': [576], 'Ernest': [577], 'C,': [578], 'Rheumatology.': [581, 590], '2014;': [582], '53:': [583], '2143-2154.': [584], '[3]': [585], 'Honda': [586], 'S,': [587], '2023;': [591], '6:': [592], '2272-2283.': [593], '<h3>Acknowledgements:</h3>': [594], 'authors': [596], 'would': [597], 'express': [600], 'sincere': [601], 'thanks': [602], 'all': [604], 'people': [606], 'involved': [607], 'project.': [612], '<h3>Disclosure': [613], 'Interests:</h3>': [615], 'Mayuko': [616], 'Fujisaki:': [617], 'None': [618, 622], 'declared,': [619, 623], 'Suguru': [620], 'Honda:': [621], 'Katsunori': [624], 'Ikari': [625], 'Asahi': [626, 707, 810], 'Kasei': [627, 708, 811], 'Pharma': [628, 631, 664, 674, 689, 700, 711, 730, 749, 793, 814, 838, 859], 'Co.,': 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