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'tumor': [168, 203], 'tissue': [169, 204], 'using': [170, 209], 'next-generation': [171], 'sequencing,': [172], 'fluorescence': [173], 'situ': [175], 'hybridization': [176], '(FISH),': [177], 'similar': [179], 'assays,': [180], 'defined': [182], 'as': [183], 'FGFR1/centromere': [184], '8': [185], 'ratio': [186], '≥5': [187], 'copy': [190], 'number': [191], '≥10': [192], 'signals': [193], 'cell.': [195], 'Local': [196], 'determination': [198], 'results': [199, 454, 508], 'confirmed': [201, 325], 'by': [205], 'central': [207], 'laboratory': [208], 'FISH.': [210], 'oral': [213], '20': [215], 'mg': [216], 'once': [217], 'daily': [218], 'standard': [220], 'dosing': [222], 'until': [223], 'progression,': [225], 'unacceptable': [226], 'toxicity,': [227], 'other': [229], 'discontinuation': [230], 'criteria': [231], 'met.': [233], 'primary': [235], 'endpoint': [236], '6-month': [239], 'progression-free': [240], 'survival': [241], '(PFS)': [242], 'rate.': [243], 'Key': [244], 'secondary': [245], 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