Title: The Therapeutic Effect of Quyu Jiedu Xiaozheng Tang Combined with Diqu Progesterone Tablets on Endometriosis and Its Effect on Serum MIF and TGF- Β Impact Of 1
Abstract: To observe the clinical efficacy of Quyu Jiedu Xiaozheng Tang combined with Diqu Progesterone Tablets in the treatment of patients with endometriosis, and to analyze the serum MIF and TGF of patients- β the impact of 1. 60 EM patients were selected and randomly divided into a traditional Chinese medicine group, a combination of traditional Chinese and Western medicine group, and a western medicine group, with 20 cases each. The traditional Chinese medicine group was given oral Quyu Jiedu Xiaozheng Tang; The Western medicine group was given oral Dafu Tong (Diqu Progesterone Tablets); The combination of traditional Chinese and Western medicine group was given a combined oral administration of Quyu Jiedu Xiaozheng Tang and Diqu Progesterone Tablets. After three consecutive months of treatment, the clinical efficacy and total effective rate of the three groups of patients were compared. Enzyme linked immunosorbent assay (ELISA) was used to detect the levels of macrophage migration inhibitory factor (MIF) and transforming growth factor (TGF) in the serum of the three groups of patients before and after treatment- β 1 level. The total effective rate (95%) of clinical efficacy in the combination of traditional Chinese and Western medicine group is better than that in the traditional Chinese medicine group (90%) and the western medicine group (90%); After treatment, the serum MIF levels of the three groups of patients were significantly reduced compared to before treatment, and P (0.033) in the combination of Chinese and Western medicine group was lower than P (0.036) in the traditional Chinese medicine group and P (0.036) in the western medicine group; Serum TGF of the three groups after treatment- β All levels were significantly lower than before treatment, and P (0.035) in the combination of traditional Chinese and Western medicine group was lower than P (0.043) in the traditional Chinese medicine group and P (0.042) in the western medicine group. The P-values are all<0.05, indicating significant significance in the experiment. Conclusion: Quyu Jiedu Xiaozheng Tang combined with Diqu Progesterone Tablets can effectively alleviate the clinical symptoms of patients with endometriosis, and can reduce the serum MIF and TGF of patients- β At the first level, the clinical effect of combining traditional Chinese and Western medicine in treating EM is more significant than that of traditional Chinese medicine and Western medicine alone. Its mechanism of action may be related to the regulation of macrophage migration inhibitory factor MIF and transforming growth factor TGF- β 1. Related.