In Response to p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?

Name: Work Video:
Duration: 3 min 30 s
Description: Sakamoto, Ikuko MD; Kagami, Keiko MD; Nozaki, Takahiro MD; Hirotsu, Yosuke PhD; Amemiya, Kenji PhD; Oyama, Toshio MD; Omata, Masao MD, PhD Author Information
Ikuko Sakamoto; Keiko Kagami; Takahiro Nozaki; Yosuke Hirotsu; Kenji Amemiya; Toshio Oyama; Masao Omata
{'id': 'https://openalex.org/W4391033711', 'doi': 'https://doi.org/10.1097/pas.0000000000002181', 'title': 'In Response to p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?', 'display_name': 'In Response to p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?', 'publication_year': 2024, 'publication_date': '2024-01-19', 'ids': {'openalex': 'https://openalex.org/W4391033711', 'doi': 'https://doi.org/10.1097/pas.0000000000002181', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/38238975'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/pas.0000000000002181', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S37879208', 'display_name': 'The American Journal of Surgical Pathology', 'issn_l': '0147-5185', 'issn': ['0147-5185', '1532-0979'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048281583', 'display_name': 'Ikuko Sakamoto', 'orcid': 'https://orcid.org/0000-0002-8990-9899'}, 'institutions': [{'id': 'https://openalex.org/I4210163952', 'display_name': 'Beijing Obstetrics and Gynecology Hospital', 'ror': 'https://ror.org/05787my06', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210163952']}, {'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}], 'countries': ['CN', 'JP'], 'is_corresponding': True, 'raw_author_name': 'Ikuko Sakamoto', 'raw_affiliation_strings': ['Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'Obstetrics & Gynecology'], 'affiliations': [{'raw_affiliation_string': 'Obstetrics & Gynecology', 'institution_ids': ['https://openalex.org/I4210163952']}, {'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046559142', 'display_name': 'Keiko Kagami', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210163952', 'display_name': 'Beijing Obstetrics and Gynecology Hospital', 'ror': 'https://ror.org/05787my06', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210163952']}, {'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}], 'countries': ['CN', 'JP'], 'is_corresponding': True, 'raw_author_name': 'Keiko Kagami', 'raw_affiliation_strings': ['Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'Obstetrics & Gynecology'], 'affiliations': [{'raw_affiliation_string': 'Obstetrics & Gynecology', 'institution_ids': ['https://openalex.org/I4210163952']}, {'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034368185', 'display_name': 'Takahiro Nozaki', 'orcid': 'https://orcid.org/0000-0001-7191-4174'}, 'institutions': [{'id': 'https://openalex.org/I4210163952', 'display_name': 'Beijing Obstetrics and Gynecology Hospital', 'ror': 'https://ror.org/05787my06', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210163952']}, {'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}], 'countries': ['CN', 'JP'], 'is_corresponding': True, 'raw_author_name': 'Takahiro Nozaki', 'raw_affiliation_strings': ['Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'Obstetrics & Gynecology'], 'affiliations': [{'raw_affiliation_string': 'Obstetrics & Gynecology', 'institution_ids': ['https://openalex.org/I4210163952']}, {'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001342594', 'display_name': 'Yosuke Hirotsu', 'orcid': 'https://orcid.org/0000-0002-8002-834X'}, 'institutions': [{'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yosuke Hirotsu', 'raw_affiliation_strings': ['Genome Analysis Center, Yamanashi Central Hospital, Yamanashi'], 'affiliations': [{'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033420971', 'display_name': 'Kenji Amemiya', 'orcid': 'https://orcid.org/0000-0003-4223-0528'}, 'institutions': [{'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kenji Amemiya', 'raw_affiliation_strings': ['Genome Analysis Center, Yamanashi Central Hospital, Yamanashi'], 'affiliations': [{'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108235582', 'display_name': 'Toshio Oyama', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Toshio Oyama', 'raw_affiliation_strings': ['Pathology'], 'affiliations': [{'raw_affiliation_string': 'Pathology', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5034244372', 'display_name': 'Masao Omata', 'orcid': 'https://orcid.org/0000-0001-7977-1497'}, 'institutions': [{'id': 'https://openalex.org/I4210166086', 'display_name': 'Yamanashi Prefectural Central Hospital', 'ror': 'https://ror.org/05r286q94', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166086']}, {'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masao Omata', 'raw_affiliation_strings': ['Departments of Gastroenterology University of Tokyo, Tokyo, Japan', 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi'], 'affiliations': [{'raw_affiliation_string': 'Genome Analysis Center, Yamanashi Central Hospital, Yamanashi', 'institution_ids': ['https://openalex.org/I4210166086']}, {'raw_affiliation_string': 'Departments of Gastroenterology University of Tokyo, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5048281583', 'https://openalex.org/A5046559142', 'https://openalex.org/A5034368185'], 'corresponding_institution_ids': ['https://openalex.org/I4210163952', 'https://openalex.org/I4210166086', 'https://openalex.org/I4210163952', 'https://openalex.org/I4210166086', 'https://openalex.org/I4210163952', 'https://openalex.org/I4210166086'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 84}, 'biblio': {'volume': '48', 'issue': '3', 'first_page': '374', 'last_page': '375'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10668', 'display_name': 'Endometrial and Cervical Cancer Treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2729', 'display_name': 'Obstetrics and Gynecology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10668', 'display_name': 'Endometrial and Cervical Cancer Treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2729', 'display_name': 'Obstetrics and Gynecology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10146', 'display_name': 'Cervical Cancer and HPV Research', 'score': 0.9884, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10253', 'display_name': 'Sarcoma Diagnosis and Treatment', 'score': 0.9828, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/p53-expression', 'display_name': 'P53 expression', 'score': 0.46007}], 'concepts': [{'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.67776173}, {'id': 'https://openalex.org/C2777088508', 'wikidata': 'https://www.wikidata.org/wiki/Q944777', 'display_name': 'Endometrial cancer', 'level': 3, 'score': 0.60767996}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5128413}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.47065702}, {'id': 'https://openalex.org/C3017404179', 'wikidata': 'https://www.wikidata.org/wiki/Q283350', 'display_name': 'P53 expression', 'level': 3, 'score': 0.46007}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3889675}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.37270162}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.36920917}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.3572377}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34222883}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3237504}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.26096255}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2473337}], 'mesh': [{'descriptor_ui': 'D016889', 'descriptor_name': 'Endometrial Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016158', 'descriptor_name': 'Genes, p53', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/pas.0000000000002181', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S37879208', 'display_name': 'The American Journal of Surgical Pathology', 'issn_l': '0147-5185', 'issn': ['0147-5185', '1532-0979'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/38238975', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.55, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 13, 'referenced_works': ['https://openalex.org/W140145949', 'https://openalex.org/W1978553767', 'https://openalex.org/W1979168838', 'https://openalex.org/W2033737920', 'https://openalex.org/W2726573208', 'https://openalex.org/W2995292698', 'https://openalex.org/W3039529906', 'https://openalex.org/W4281671248', 'https://openalex.org/W4283520680', 'https://openalex.org/W4323044072', 'https://openalex.org/W4385476364', 'https://openalex.org/W4386990853', 'https://openalex.org/W4387729168'], 'related_works': ['https://openalex.org/W4386948227', 'https://openalex.org/W4327964407', 'https://openalex.org/W2999877485', 'https://openalex.org/W2963059706', 'https://openalex.org/W2925992501', 'https://openalex.org/W2601182341', 'https://openalex.org/W2399421402', 'https://openalex.org/W2376996112', 'https://openalex.org/W2355920994', 'https://openalex.org/W2287113218'], 'abstract_inverted_index': {'Sakamoto,': [0], 'Ikuko': [1], 'MD;': [2, 5, 8, 17], 'Kagami,': [3], 'Keiko': [4], 'Nozaki,': [6], 'Takahiro': [7], 'Hirotsu,': [9], 'Yosuke': [10], 'PhD;': [11, 14], 'Amemiya,': [12], 'Kenji': [13], 'Oyama,': [15], 'Toshio': [16], 'Omata,': [18], 'Masao': [19], 'MD,': [20], 'PhD': [21], 'Author': [22], 'Information': [23]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4391033711', 'counts_by_year': [], 'updated_date': '2024-12-23T09:52:20.119025', 'created_date': '2024-01-20'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
