Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4389087026', 'doi': 'https://doi.org/10.58837/chula.the.2016.1909', 'title': 'Parasite burden, distribution and immunopathology of Leishmania Martiniquensis - infected BALB/c mice in different routes and time points', 'display_name': 'Parasite burden, distribution and immunopathology of Leishmania Martiniquensis - infected BALB/c mice in different routes and time points', 'publication_year': 2016, 'publication_date': '2016-01-01', 'ids': {'openalex': 'https://openalex.org/W4389087026', 'doi': 'https://doi.org/10.58837/chula.the.2016.1909'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1909', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60706/1/5775307131.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'dissertation', 'type_crossref': 'dissertation', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60706/1/5775307131.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004139577', 'display_name': 'Nawaphat Somboonpoonpol', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Nawaphat Somboonpoonpol', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5004139577'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.910711, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 66, 'max': 73}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10890', 'display_name': 'Trypanosoma species research and implications', 'score': 0.9319, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/giemsa-stain', 'display_name': 'Giemsa stain', 'score': 0.5279395}, {'id': 'https://openalex.org/keywords/balb/c', 'display_name': 'BALB/c', 'score': 0.49888444}, {'id': 'https://openalex.org/keywords/parasite-load', 'display_name': 'Parasite load', 'score': 0.45918956}], 'concepts': [{'id': 'https://openalex.org/C2780931953', 'wikidata': 'https://www.wikidata.org/wiki/Q9371', 'display_name': 'Spleen', 'level': 2, 'score': 0.7532345}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6036672}, {'id': 'https://openalex.org/C2781092759', 'wikidata': 'https://www.wikidata.org/wiki/Q524818', 'display_name': 'Leishmania', 'level': 3, 'score': 0.58716494}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.55437624}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.54268104}, {'id': 'https://openalex.org/C154488023', 'wikidata': 'https://www.wikidata.org/wiki/Q1412684', 'display_name': 'Giemsa stain', 'level': 2, 'score': 0.5279395}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.5245369}, {'id': 'https://openalex.org/C2776529007', 'wikidata': 'https://www.wikidata.org/wiki/Q9820', 'display_name': 'BALB/c', 'level': 3, 'score': 0.49888444}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.49403268}, {'id': 'https://openalex.org/C2776555147', 'wikidata': 'https://www.wikidata.org/wiki/Q331283', 'display_name': 'Leishmaniasis', 'level': 2, 'score': 0.4636845}, {'id': 'https://openalex.org/C2775993617', 'wikidata': 'https://www.wikidata.org/wiki/Q7135939', 'display_name': 'Parasite load', 'level': 3, 'score': 0.45918956}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.31341445}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3132185}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1909', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60706/1/5775307131.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1909', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60706/1/5775307131.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.46, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 104, 'referenced_works': ['https://openalex.org/W13689119', 'https://openalex.org/W1625161850', 'https://openalex.org/W1676233161', 'https://openalex.org/W1781333175', 'https://openalex.org/W1927625726', 'https://openalex.org/W1942989476', 'https://openalex.org/W1964281876', 'https://openalex.org/W1970594670', 'https://openalex.org/W1971413150', 'https://openalex.org/W1974637759', 'https://openalex.org/W1976285859', 'https://openalex.org/W1976502466', 'https://openalex.org/W1977433737', 'https://openalex.org/W1981265117', 'https://openalex.org/W1983115164', 'https://openalex.org/W1985561876', 'https://openalex.org/W1999851802', 'https://openalex.org/W2001269371', 'https://openalex.org/W2002204067', 'https://openalex.org/W2003948064', 'https://openalex.org/W2004637228', 'https://openalex.org/W2005736123', 'https://openalex.org/W2021861978', 'https://openalex.org/W2022367345', 'https://openalex.org/W2026227162', 'https://openalex.org/W2029618039', 'https://openalex.org/W2034662800', 'https://openalex.org/W2035591436', 'https://openalex.org/W2041858338', 'https://openalex.org/W2043819612', 'https://openalex.org/W2050289380', 'https://openalex.org/W2051012840', 'https://openalex.org/W2053662296', 'https://openalex.org/W2054304937', 'https://openalex.org/W2054408809', 'https://openalex.org/W2055936527', 'https://openalex.org/W2056357203', 'https://openalex.org/W2058411735', 'https://openalex.org/W2065993567', 'https://openalex.org/W2066304801', 'https://openalex.org/W2067230332', 'https://openalex.org/W2072179326', 'https://openalex.org/W2074871124', 'https://openalex.org/W2077508307', 'https://openalex.org/W2077771769', 'https://openalex.org/W2078167750', 'https://openalex.org/W2083942660', 'https://openalex.org/W2084208767', 'https://openalex.org/W2084307437', 'https://openalex.org/W2084424946', 'https://openalex.org/W2085140284', 'https://openalex.org/W2098803611', 'https://openalex.org/W2101643689', 'https://openalex.org/W2104339935', 'https://openalex.org/W2106477955', 'https://openalex.org/W2107255267', 'https://openalex.org/W2107915297', 'https://openalex.org/W2108764388', 'https://openalex.org/W2109942566', 'https://openalex.org/W2112930860', 'https://openalex.org/W2115200208', 'https://openalex.org/W2124822408', 'https://openalex.org/W2129514368', 'https://openalex.org/W2142002667', 'https://openalex.org/W2146087941', 'https://openalex.org/W2153101029', 'https://openalex.org/W2153905933', 'https://openalex.org/W2159416923', 'https://openalex.org/W2161170793', 'https://openalex.org/W2162027668', 'https://openalex.org/W2165529080', 'https://openalex.org/W2166719409', 'https://openalex.org/W2168952903', 'https://openalex.org/W2172156604', 'https://openalex.org/W2189751621', 'https://openalex.org/W2193913260', 'https://openalex.org/W2215373933', 'https://openalex.org/W2239925678', 'https://openalex.org/W2293039793', 'https://openalex.org/W2294083761', 'https://openalex.org/W2297718342', 'https://openalex.org/W2303711840', 'https://openalex.org/W2326802936', 'https://openalex.org/W2336740755', 'https://openalex.org/W2339170085', 'https://openalex.org/W2339970694', 'https://openalex.org/W2346030070', 'https://openalex.org/W2397198853', 'https://openalex.org/W2404548598', 'https://openalex.org/W2416243957', 'https://openalex.org/W2416617891', 'https://openalex.org/W2482196116', 'https://openalex.org/W2530370714', 'https://openalex.org/W2564662561', 'https://openalex.org/W2578070438', 'https://openalex.org/W2586685014', 'https://openalex.org/W2595395022', 'https://openalex.org/W3020875554', 'https://openalex.org/W36200704', 'https://openalex.org/W4211078476', 'https://openalex.org/W4242478859', 'https://openalex.org/W4247505079', 'https://openalex.org/W4295880516', 'https://openalex.org/W592946618'], 'related_works': ['https://openalex.org/W77589466', 'https://openalex.org/W334351926', 'https://openalex.org/W3011144756', 'https://openalex.org/W240176760', 'https://openalex.org/W2274295327', 'https://openalex.org/W2168408102', 'https://openalex.org/W2113811423', 'https://openalex.org/W2097748530', 'https://openalex.org/W2077642200', 'https://openalex.org/W2035581907'], 'abstract_inverted_index': {'Leishmaniasis': [0], 'is': [1, 289, 297], 'an': [2], 'emerging': [3], 'zoonotic': [4], 'vector-borne': [5], 'disease': [6], 'in': [7, 23, 32, 60, 147, 157, 180, 191, 204, 217, 271, 304, 329], 'Thailand': [8], 'transmitted': [9], 'by': [10, 307], 'the': [11, 54, 119, 187, 205, 248, 274, 290, 317], 'bite': [12], 'of': [13, 48, 79, 121, 170, 231, 258, 265, 276, 319, 326], 'a': [14, 298], 'tiny': [15], 'female': [16], 'phlebotomine': [17], 'sandfly.': [18], 'Autochthonous': [19], 'L.': [20, 61, 80, 223, 282, 295, 327], 'martiniquensis': [21, 81, 283, 296, 328], 'infection': [22], 'Thai': [24], 'patients': [25, 33], 'has': [26], 'been': [27], 'continuously': [28], 'reported': [29], 'since': [30], '2014': [31], 'co-infected': [34], 'with': [35, 39, 76, 263], 'HIV,': [36], 'immunocompetent': [37], 'patient': [38], 'or': [40], 'without': [41], 'underlying': [42], 'diseases': [43], 'and': [44, 58, 72, 87, 109, 141, 164, 172, 237, 251, 260, 312], 'children.': [45], 'The': [46, 229], 'objective': [47], 'this': [49, 287], 'study': [50, 288], 'was': [51, 128, 174, 193, 202, 227, 243], 'to': [52, 176, 280, 292], 'investigate': [53], 'parasite': [55, 178, 189], 'burden,': [56], 'distribution': [57, 120], 'immunopathology': [59], 'martiniquensis-infected': [62, 224], 'BALB/c': [63, 136, 277, 305], 'mice.': [64], 'Sixteen': [65], 'mice': [66, 95, 144, 306], 'were': [67, 96, 111, 132, 155], 'intraperitoneally,': [68], 'i.p.,': [69], 'intravenously,': [70], 'i.v.,': [71], 'subcutaneously,': [73], 's.c.,': [74], 'infected': [75], '5x106': [77], 'promastigotes': [78], 'each.': [82], 'On': [83], '7,': [84, 235], '14,': [85], '28': [86, 238], '112': [88, 208, 269], 'days': [89], 'post': [90], 'infection,': [91], 'dpi,': [92, 197, 209], '4': [93], 'inoculated': [94, 138], 'euthanized': [97], 'from': [98, 134, 161, 240], 'each': [99, 114], 'inoculation': [100, 309], 'group.': [101], 'Blood,': [102], 'livers,': [103], 'spleens,': [104], 'bone': [105], 'marrows,': [106], 'salivary': [107], 'glands': [108], 'kidneys': [110], 'collected': [112], 'at': [113], 'time': [115, 149, 159], 'points.': [116, 150], 'To': [117, 212], 'detect': [118], 'parasite,': [122], 'PCR': [123], 'targeting': [124], 'Leishmania-specific': [125], 'ITS1': [126], 'genes': [127], 'performed.': [129, 228], 'DNA': [130], 'amplicons': [131], 'detected': [133], 'all': [135, 143, 148, 158], 'livers': [137, 272], 'via': [139, 145, 310], 'i.v.': [140, 163, 185, 241, 311], 'almost': [142], 'i.p.': [146, 165, 313], 'For': [151], 'spleen,': [152], 'Leishmania': [153], 'DNAs': [154, 325], 'present': [156], 'points': [160], 'both': [162], 'routes.': [166], 'Giemsa-stained': [167], 'impression': [168], 'smear': [169], 'liver': [171, 192], 'spleen': [173, 206], 'conducted': [175], 'analyse': [177], 'burden': [179, 190], 'Leishman-Donovan': [181], 'unit': [182], '(LDU).': [183], 'Via': [184], 'route,': [186], 'highest': [188], 'found': [194, 244], 'on': [195, 207, 234, 268, 316], '7': [196], '101': [198], 'LDU,': [199], 'whereas': [200], 'it': [201], 'shown': [203], '3.1': [210], 'LDU.': [211], 'evaluate': [213], 'cell-mediated': [214], 'immune': [215], 'responses': [216], 'liver,': [218], 'indirect': [219], 'immunohistochemical': [220], 'staining': [221], 'using': [222], 'human': [225], 'serum': [226], 'number': [230], 'mature': [232, 261], 'granuloma': [233, 262, 267], '14': [236], 'dpi': [239, 270], 'route': [242], 'significantly': [245], 'superior': [246], 'than': [247], 'non-infected': [249], 'control': [250, 281], 'other': [252], 'routes': [253, 314], '(p': [254], '<': [255], '0.05).': [256], 'Reduction': [257], 'immature': [259], 'development': [264], 'involuting': [266], 'revealed': [273], 'ability': [275], 'cellular': [278], 'immunity': [279], 'infection.': [284], 'In': [285], 'conclusion,': [286], 'first': [291], 'reveal': [293], 'that': [294], 'causative': [299], 'agent': [300], 'for': [301], 'visceral': [302], 'leishmaniasis': [303], 'experimental': [308], 'based': [315], 'presence': [318], 'amastigotes': [320], 'as': [321, 323], 'well': [322], 'genomic': [324], 'important': [330], 'target': [331], 'organs.': [332]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4389087026', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-16T09:18:56.179653', 'created_date': '2023-11-29'}