Publication Information

{'id': 'https://openalex.org/W4388914379', 'doi': 'https://doi.org/10.1016/j.jep.2023.117480', 'title': 'Exploring the potential mechanism of Heng-Gu-Gu-Shang-Yu-He-Ji therapy for osteoporosis based on network pharmacology and transcriptomics', 'display_name': 'Exploring the potential mechanism of Heng-Gu-Gu-Shang-Yu-He-Ji therapy for osteoporosis based on network pharmacology and transcriptomics', 'publication_year': 2023, 'publication_date': '2023-11-22', 'ids': {'openalex': 'https://openalex.org/W4388914379', 'doi': 'https://doi.org/10.1016/j.jep.2023.117480', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37995823'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jep.2023.117480', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S29564236', 'display_name': 'Journal of Ethnopharmacology', 'issn_l': '0378-8741', 'issn': ['0378-8741', '1872-7573'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101270046', 'display_name': 'Linbi Xie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I53411278', 'display_name': 'Chengdu University of Traditional Chinese Medicine', 'ror': 'https://ror.org/00pcrz470', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I53411278']}, {'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Linbi Xie', 'raw_affiliation_strings': ['Chengdu University of Traditional Chinese Medicine (TCM) School of Pharmacy, Chengdu, 610041, China', 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Chengdu University of Traditional Chinese Medicine (TCM) School of Pharmacy, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I53411278']}, {'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101270047', 'display_name': 'Song Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223893228', 'display_name': 'National Medical Products Administration', 'ror': 'https://ror.org/002k3wk88', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I223893228']}, {'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xu Song', 'raw_affiliation_strings': ['NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial & Institute of Regulatory Science for Medical Devices & NMPA Research Base of Regulatory Science for Medical Devices, Sichuan University, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial & Institute of Regulatory Science for Medical Devices & NMPA Research Base of Regulatory Science for Medical Devices, Sichuan University, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I223893228', 'https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102582335', 'display_name': 'Lei Ling', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ling Lei', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100741518', 'display_name': 'Chu Chen', 'orcid': 'https://orcid.org/0000-0003-2267-8050'}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chu Chen', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101537293', 'display_name': 'Huan Zhao', 'orcid': 'https://orcid.org/0000-0002-7459-6922'}, 'institutions': [{'id': 'https://openalex.org/I53411278', 'display_name': 'Chengdu University of Traditional Chinese Medicine', 'ror': 'https://ror.org/00pcrz470', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I53411278']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huan Zhao', 'raw_affiliation_strings': ['Chengdu University of Traditional Chinese Medicine (TCM) School of Pharmacy, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Chengdu University of Traditional Chinese Medicine (TCM) School of Pharmacy, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I53411278']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110646321', 'display_name': 'Jingyi Hu', 'orcid': 'https://orcid.org/0000-0001-7726-6753'}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jingyi Hu', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100397995', 'display_name': 'Yue Yu', 'orcid': 'https://orcid.org/0000-0003-0633-9577'}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yue Yu', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113052309', 'display_name': 'Xiaolu Bai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaolu Bai', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100740263', 'display_name': 'Xia Wu', 'orcid': 'https://orcid.org/0000-0002-8151-8076'}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xia Wu', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101856901', 'display_name': 'Xiangfeng Li', 'orcid': 'https://orcid.org/0000-0002-7400-9900'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiangfeng Li', 'raw_affiliation_strings': ['National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100777982', 'display_name': 'Xiao Yang', 'orcid': 'https://orcid.org/0000-0001-7248-8218'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao Yang', 'raw_affiliation_strings': ['National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100770283', 'display_name': 'Bo Yuan', 'orcid': 'https://orcid.org/0009-0000-8482-3212'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bo Yuan', 'raw_affiliation_strings': ['National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100718414', 'display_name': 'Dongxiao Li', 'orcid': 'https://orcid.org/0000-0002-1996-143X'}, 'institutions': [{'id': 'https://openalex.org/I4210157155', 'display_name': 'Sichuan Academy of Traditional Chinese Medicine', 'ror': 'https://ror.org/05wad7k45', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157155']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Dongxiao Li', 'raw_affiliation_strings': ['Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China'], 'affiliations': [{'raw_affiliation_string': 'Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China', 'institution_ids': ['https://openalex.org/I4210157155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050407938', 'display_name': 'Xiangdong Zhu', 'orcid': 'https://orcid.org/0000-0002-3818-7419'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xiangdong Zhu', 'raw_affiliation_strings': ['National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5115587777', 'display_name': 'Xingdong Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xingdong Zhang', 'raw_affiliation_strings': ['National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'National Engineering Research Center for Biomaterials & School of Biomedical Engineering, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5100718414', 'https://openalex.org/A5050407938'], 'corresponding_institution_ids': ['https://openalex.org/I4210157155', 'https://openalex.org/I24185976'], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.781, 'has_fulltext': False, 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.499258, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 88}, 'biblio': {'volume': '321', 'issue': None, 'first_page': '117480', 'last_page': '117480'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11219', 'display_name': 'Bone Metabolism and Diseases', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11219', 'display_name': 'Bone Metabolism and Diseases', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10071', 'display_name': 'Bone health and osteoporosis research', 'score': 0.9836, 'subfield': {'id': 'https://openalex.org/subfields/2732', 'display_name': 'Orthopedics and Sports Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14364', 'display_name': 'Clusterin in disease pathology', 'score': 0.9818, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/kegg', 'display_name': 'KEGG', 'score': 0.54725707}], 'concepts': [{'id': 'https://openalex.org/C2780426850', 'wikidata': 'https://www.wikidata.org/wiki/Q3357478', 'display_name': 'Osteoprotegerin', 'level': 4, 'score': 0.6529899}, {'id': 'https://openalex.org/C2776541429', 'wikidata': 'https://www.wikidata.org/wiki/Q165328', 'display_name': 'Osteoporosis', 'level': 2, 'score': 0.59413576}, {'id': 'https://openalex.org/C2779428903', 'wikidata': 'https://www.wikidata.org/wiki/Q418934', 'display_name': 'RANKL', 'level': 4, 'score': 0.58560133}, {'id': 'https://openalex.org/C86554907', 'wikidata': 'https://www.wikidata.org/wiki/Q285613', 'display_name': 'PI3K/AKT/mTOR pathway', 'level': 3, 'score': 0.55087614}, {'id': 'https://openalex.org/C152724338', 'wikidata': 'https://www.wikidata.org/wiki/Q909442', 'display_name': 'KEGG', 'level': 5, 'score': 0.54725707}, {'id': 'https://openalex.org/C75217442', 'wikidata': 'https://www.wikidata.org/wiki/Q423650', 'display_name': 'Protein kinase B', 'level': 3, 'score': 0.5457359}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42603916}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42001405}, {'id': 'https://openalex.org/C162317418', 'wikidata': 'https://www.wikidata.org/wiki/Q252857', 'display_name': 'Transcriptome', 'level': 4, 'score': 0.40770853}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.3751803}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33633447}, {'id': 'https://openalex.org/C88045685', 'wikidata': 'https://www.wikidata.org/wiki/Q174576', 'display_name': 'Activator (genetics)', 'level': 3, 'score': 0.3308733}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.31944576}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.26231834}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.21484825}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.19375104}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.14826986}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.10619596}], 'mesh': [{'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004365', 'descriptor_name': 'Drugs, Chinese Herbal', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062105', 'descriptor_name': 'Molecular Docking Simulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000091484', 'descriptor_name': 'Network Pharmacology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010024', 'descriptor_name': 'Osteoporosis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D053244', 'descriptor_name': 'Osteoprotegerin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019869', 'descriptor_name': 'Phosphatidylinositol 3-Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051057', 'descriptor_name': 'Proto-Oncogene Proteins c-akt', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jep.2023.117480', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S29564236', 'display_name': 'Journal of Ethnopharmacology', 'issn_l': '0378-8741', 'issn': ['0378-8741', '1872-7573'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37995823', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.49, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1967593662', 'https://openalex.org/W1987612487', 'https://openalex.org/W1993517337', 'https://openalex.org/W2005646573', 'https://openalex.org/W2030861926', 'https://openalex.org/W2044602219', 'https://openalex.org/W2051559976', 'https://openalex.org/W2053869914', 'https://openalex.org/W2055447253', 'https://openalex.org/W2059257872', 'https://openalex.org/W2098868165', 'https://openalex.org/W2109648113', 'https://openalex.org/W2115547357', 'https://openalex.org/W2165275292', 'https://openalex.org/W2169844701', 'https://openalex.org/W2312282875', 'https://openalex.org/W2339017094', 'https://openalex.org/W2369391196', 'https://openalex.org/W2416653136', 'https://openalex.org/W2808194379', 'https://openalex.org/W2883591283', 'https://openalex.org/W2921162267', 'https://openalex.org/W2942823817', 'https://openalex.org/W2944113426', 'https://openalex.org/W2955175928', 'https://openalex.org/W2990211826', 'https://openalex.org/W3005516444', 'https://openalex.org/W3005722875', 'https://openalex.org/W3010608056', 'https://openalex.org/W3032923458', 'https://openalex.org/W3043689844', 'https://openalex.org/W3085623132', 'https://openalex.org/W3090967605', 'https://openalex.org/W3097116631', 'https://openalex.org/W3113196940', 'https://openalex.org/W3122919452', 'https://openalex.org/W3169538861', 'https://openalex.org/W3178105104', 'https://openalex.org/W3178602675', 'https://openalex.org/W3213364292', 'https://openalex.org/W4200042052', 'https://openalex.org/W4200241873', 'https://openalex.org/W4220992533', 'https://openalex.org/W4280650248', 'https://openalex.org/W4281643853', 'https://openalex.org/W4281670608', 'https://openalex.org/W4283722337', 'https://openalex.org/W4289521172', 'https://openalex.org/W4292507552', 'https://openalex.org/W4294631340', 'https://openalex.org/W4296807158', 'https://openalex.org/W4372331533'], 'related_works': ['https://openalex.org/W4310330039', 'https://openalex.org/W3032163834', 'https://openalex.org/W2405442170', 'https://openalex.org/W2393213763', 'https://openalex.org/W2377224820', 'https://openalex.org/W2373306182', 'https://openalex.org/W2361950189', 'https://openalex.org/W2359313837', 'https://openalex.org/W2355713854', 'https://openalex.org/W1982381891'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4388914379', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}], 'updated_date': '2024-12-24T03:07:05.579921', 'created_date': '2023-11-23'}