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'cytidine': [18, 105, 164], 'deaminase': [19, 25, 85, 165, 190], '(CDD),': [20], 'or': [21], 'deoxycytidine': [23, 111, 181], 'monophosphate': [24], '(dCMP': [26], 'deaminase).': [27], 'Additional': [28], 'metabolic': [29], 'pathways,': [30], 'such': [31], 'as': [32, 197, 199], 'phosphorylation,': [33], 'can': [34, 167, 191], 'substantially': [35], 'contribute': [36], 'to': [37, 67, 99, 144, 171, 208], 'their': [38, 163], '(in)activation.': [39], 'Here,': [40], 'a': [41, 121, 133], 'new': [42], 'technique': [43, 95, 175, 204], 'analysis': [46], 'these': [48], 'pathways': [49], 'in': [50, 86, 142, 153, 194], 'cells': [51, 151], 'is': [52, 55], 'described.': [53], 'It': [54], 'based': [56], 'on': [57, 113], 'use': [59, 72], '5-ethynyl': [61, 68], '2′-deoxycytidine': [62], '(EdC)': [63], 'and': [64, 83, 89, 110, 123, 162, 186, 215], 'its': [65], 'conversion': [66], '2′-deoxyuridine': [69], '(EdU).': [70], 'Its': [71], 'was': [73], 'tested': [74], 'estimation': [77], 'role': [80], 'CDD': [82, 136, 160], 'dCMP': [84, 108, 172, 189], 'five': [87], 'cancer': [88, 146], 'four': [90], 'non-cancer': [91, 150], 'cell': [92, 130], 'lines.': [93], 'The': [94, 138, 174], 'provides': [96, 205], 'possibility': [98, 207], 'address': [100], 'aggregated': [102], 'impact': [103], 'transporters,': [106], 'CDD,': [107], 'deaminase,': [109], 'kinase': [112, 182], 'EdC': [114], 'metabolism.': [115], 'Using': [116], 'this': [117], 'technique,': [118], 'we': [119], 'developed': [120], 'quick': [122], 'cheap': [124], 'method': [125], 'identification': [128], 'lines': [131], 'exhibiting': [132], 'lack': [134], 'activity.': [137, 218], 'data': [139], 'showed': [140], 'that': [141, 188], 'contrast': [143], 'cells,': [147], 'all': [148], 'study': [155], 'exhibited': [156], 'low,': [157], 'if': [158], 'any,': [159], 'content': [161], 'activity': [166], 'be': [168, 192], 'exclusively': [169], 'attributed': [170], 'deaminase.': [173], 'also': [176], 'confirmed': [177], 'importance': [179], 'dCas': [184, 195], 'metabolism': [185], 'indicated': [187], 'fundamental': [193], 'deamination': [196], 'well': [198], 'CDD.': [200], 'Moreover,': [201], 'described': [203], 'perform': [209], 'simultaneous': [211], 'testing': [212], 'cytotoxicity': [214], 'DNA': [216], 'replication': [217]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4388893320', 'counts_by_year': [], 'updated_date': '2024-09-11T02:49:46.204548', 'created_date': '2023-11-23'}