Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4388538929', 'doi': 'https://doi.org/10.1007/s12325-023-02652-5', 'title': 'Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium–Glucose Cotransporter 2 Inhibitors', 'display_name': 'Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium–Glucose Cotransporter 2 Inhibitors', 'publication_year': 2023, 'publication_date': '2023-11-09', 'ids': {'openalex': 'https://openalex.org/W4388538929', 'doi': 'https://doi.org/10.1007/s12325-023-02652-5', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37943443'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s12325-023-02652-5', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s12325-023-02652-5.pdf', 'source': {'id': 'https://openalex.org/S27230875', 'display_name': 'Advances in Therapy', 'issn_l': '0741-238X', 'issn': ['0741-238X', '1865-8652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://link.springer.com/content/pdf/10.1007/s12325-023-02652-5.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080334509', 'display_name': 'Subodh Verma', 'orcid': 'https://orcid.org/0000-0002-4018-8533'}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I1297363086', 'display_name': "St. Michael's Hospital", 'ror': 'https://ror.org/04skqfp25', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1297363086', 'https://openalex.org/I4399598460']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Subodh Verma', 'raw_affiliation_strings': ['Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. [email protected].', 'Department of Surgery, University of Toronto, Toronto, ON, Canada. [email protected].', "Division of Cardiac Surgery, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada. [email protected]."], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, University of Toronto, Toronto, ON, Canada. [email protected].', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': 'Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. [email protected].', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': "Division of Cardiac Surgery, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada. [email protected].", 'institution_ids': ['https://openalex.org/I1297363086']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004971001', 'display_name': 'Sunder Mudaliar', 'orcid': 'https://orcid.org/0000-0002-1133-7771'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I2799886695', 'display_name': 'Veterans Health Administration', 'ror': 'https://ror.org/05eq41471', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sunder Mudaliar', 'raw_affiliation_strings': ['Department of Medicine, University of California, San Diego, CA, USA.', 'Endocrinology/Diabetes Section, Veterans Affairs Medical Centre, San Diego, CA, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California, San Diego, CA, USA.', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'Endocrinology/Diabetes Section, Veterans Affairs Medical Centre, San Diego, CA, USA.', 'institution_ids': ['https://openalex.org/I2799886695']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5020663562', 'display_name': 'Peter J. Greasley', 'orcid': 'https://orcid.org/0000-0002-2529-4477'}, 'institutions': [{'id': 'https://openalex.org/I4210143795', 'display_name': 'AstraZeneca (Sweden)', 'ror': 'https://ror.org/04wwrrg31', 'country_code': 'SE', 'type': 'company', 'lineage': ['https://openalex.org/I105036370', 'https://openalex.org/I4210143795']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Peter J Greasley', 'raw_affiliation_strings': ['Early Discovery and Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.'], 'affiliations': [{'raw_affiliation_string': 'Early Discovery and Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.', 'institution_ids': ['https://openalex.org/I4210143795']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'fwci': 1.18, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.999129, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '41', 'issue': '1', 'first_page': '92', 'last_page': '112'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10401', 'display_name': 'Diabetes Treatment and Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10401', 'display_name': 'Diabetes Treatment and Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11339', 'display_name': 'Metabolism, Diabetes, and Cancer', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic function and diabetes', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cardiorenal-syndrome', 'display_name': 'Cardiorenal syndrome', 'score': 0.80480564}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.89603883}, {'id': 'https://openalex.org/C2781309322', 'wikidata': 'https://www.wikidata.org/wiki/Q5038718', 'display_name': 'Cardiorenal syndrome', 'level': 3, 'score': 0.80480564}, {'id': 'https://openalex.org/C2778198053', 'wikidata': 'https://www.wikidata.org/wiki/Q181754', 'display_name': 'Heart failure', 'level': 2, 'score': 0.7577627}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.6130615}, {'id': 'https://openalex.org/C2778653478', 'wikidata': 'https://www.wikidata.org/wiki/Q1054718', 'display_name': 'Kidney disease', 'level': 2, 'score': 0.57769126}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.48966482}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.480413}, {'id': 'https://openalex.org/C159641895', 'wikidata': 'https://www.wikidata.org/wiki/Q108377937', 'display_name': 'Renal function', 'level': 2, 'score': 0.44708166}, {'id': 'https://openalex.org/C2777180221', 'wikidata': 'https://www.wikidata.org/wiki/Q3025883', 'display_name': 'Type 2 diabetes', 'level': 3, 'score': 0.44678652}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.41701272}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.4091182}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.2663077}], 'mesh': [{'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D006333', 'descriptor_name': 'Heart Failure', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051436', 'descriptor_name': 'Renal Insufficiency, Chronic', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D012964', 'descriptor_name': 'Sodium', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000077203', 'descriptor_name': 'Sodium-Glucose Transporter 2 Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s12325-023-02652-5', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s12325-023-02652-5.pdf', 'source': {'id': 'https://openalex.org/S27230875', 'display_name': 'Advances in Therapy', 'issn_l': '0741-238X', 'issn': ['0741-238X', '1865-8652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796581', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37943443', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s12325-023-02652-5', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s12325-023-02652-5.pdf', 'source': {'id': 'https://openalex.org/S27230875', 'display_name': 'Advances in Therapy', 'issn_l': '0741-238X', 'issn': ['0741-238X', '1865-8652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.84, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 134, 'referenced_works': ['https://openalex.org/W1493048246', 'https://openalex.org/W1521840417', 'https://openalex.org/W1689732359', 'https://openalex.org/W1888211049', 'https://openalex.org/W1990025047', 'https://openalex.org/W1994599411', 'https://openalex.org/W1999551505', 'https://openalex.org/W2020332436', 'https://openalex.org/W2040445576', 'https://openalex.org/W2042943866', 'https://openalex.org/W2072040765', 'https://openalex.org/W2089728480', 'https://openalex.org/W2113531489', 'https://openalex.org/W2125089162', 'https://openalex.org/W2128606426', 'https://openalex.org/W2133169646', 'https://openalex.org/W2134304394', 'https://openalex.org/W2135045435', 'https://openalex.org/W2140568388', 'https://openalex.org/W2145729769', 'https://openalex.org/W2146264128', 'https://openalex.org/W2153839551', 'https://openalex.org/W2164368208', 'https://openalex.org/W2168450459', 'https://openalex.org/W2210026450', 'https://openalex.org/W2412800896', 'https://openalex.org/W2416348735', 'https://openalex.org/W2492672367', 'https://openalex.org/W2498901811', 'https://openalex.org/W2515456868', 'https://openalex.org/W2516632997', 'https://openalex.org/W2523805939', 'https://openalex.org/W2532735232', 'https://openalex.org/W2538443876', 'https://openalex.org/W2551481457', 'https://openalex.org/W2582603147', 'https://openalex.org/W2583476095', 'https://openalex.org/W2587803947', 'https://openalex.org/W2601655543', 'https://openalex.org/W2605975631', 'https://openalex.org/W2617488317', 'https://openalex.org/W2618377980', 'https://openalex.org/W2624862988', 'https://openalex.org/W2626446274', 'https://openalex.org/W2734312801', 'https://openalex.org/W2751884637', 'https://openalex.org/W2758068989', 'https://openalex.org/W2762664243', 'https://openalex.org/W2763866789', 'https://openalex.org/W2764144227', 'https://openalex.org/W2765097799', 'https://openalex.org/W2765278092', 'https://openalex.org/W2772204795', 'https://openalex.org/W2772835527', 'https://openalex.org/W2781483265', 'https://openalex.org/W2782103987', 'https://openalex.org/W2792082765', 'https://openalex.org/W2800723402', 'https://openalex.org/W2809241860', 'https://openalex.org/W2809812205', 'https://openalex.org/W2884466498', 'https://openalex.org/W2884692440', 'https://openalex.org/W2896968341', 'https://openalex.org/W2897115298', 'https://openalex.org/W2899764361', 'https://openalex.org/W2899847838', 'https://openalex.org/W2900413769', 'https://openalex.org/W2908535040', 'https://openalex.org/W2912227678', 'https://openalex.org/W2920817146', 'https://openalex.org/W2936593438', 'https://openalex.org/W2939222610', 'https://openalex.org/W2943379297', 'https://openalex.org/W2946777418', 'https://openalex.org/W2964930911', 'https://openalex.org/W2964979089', 'https://openalex.org/W2966215429', 'https://openalex.org/W2967001872', 'https://openalex.org/W2970596686', 'https://openalex.org/W2970927649', 'https://openalex.org/W2972201761', 'https://openalex.org/W2974260792', 'https://openalex.org/W2979434640', 'https://openalex.org/W2982570836', 'https://openalex.org/W2989579906', 'https://openalex.org/W2990818893', 'https://openalex.org/W2995792173', 'https://openalex.org/W2996087990', 'https://openalex.org/W2996441103', 'https://openalex.org/W2996517820', 'https://openalex.org/W2999945678', 'https://openalex.org/W3004835181', 'https://openalex.org/W3005610359', 'https://openalex.org/W3006947875', 'https://openalex.org/W3007720796', 'https://openalex.org/W3008062346', 'https://openalex.org/W3008610985', 'https://openalex.org/W3011029919', 'https://openalex.org/W3013428493', 'https://openalex.org/W3013838418', 'https://openalex.org/W3034526163', 'https://openalex.org/W3035468154', 'https://openalex.org/W3036094926', 'https://openalex.org/W3088173406', 'https://openalex.org/W3096834656', 'https://openalex.org/W3097586394', 'https://openalex.org/W3123572331', 'https://openalex.org/W3126779683', 'https://openalex.org/W3132325778', 'https://openalex.org/W3136177409', 'https://openalex.org/W3157300987', 'https://openalex.org/W3157920127', 'https://openalex.org/W3163812846', 'https://openalex.org/W3179748924', 'https://openalex.org/W3183166449', 'https://openalex.org/W3187559426', 'https://openalex.org/W3193297191', 'https://openalex.org/W3201867211', 'https://openalex.org/W3202292925', 'https://openalex.org/W3202330513', 'https://openalex.org/W3203350643', 'https://openalex.org/W3212095609', 'https://openalex.org/W3217492688', 'https://openalex.org/W4200478289', 'https://openalex.org/W4205183771', 'https://openalex.org/W4206946749', 'https://openalex.org/W4220763396', 'https://openalex.org/W4225314314', 'https://openalex.org/W4293194528', 'https://openalex.org/W4293280727', 'https://openalex.org/W4293332098', 'https://openalex.org/W4293353625', 'https://openalex.org/W4293354639', 'https://openalex.org/W4308183941'], 'related_works': ['https://openalex.org/W4389179665', 'https://openalex.org/W4320929188', 'https://openalex.org/W4211206411', 'https://openalex.org/W2607143468', 'https://openalex.org/W2390666451', 'https://openalex.org/W2379135908', 'https://openalex.org/W2359469350', 'https://openalex.org/W2184493448', 'https://openalex.org/W2049186845', 'https://openalex.org/W1971368128'], 'abstract_inverted_index': {'There': [0], 'is': [1], 'a': [2, 97, 144], 'bidirectional': [3], 'pathophysiological': [4], 'interaction': [5], 'between': [6], 'the': [7, 10, 17, 20, 54, 136, 155, 165, 172, 178, 215, 223, 238], 'heart': [8, 18, 34, 103, 122, 179], 'and': [9, 12, 36, 85, 91, 105, 124, 151, 160, 180, 195, 202, 207, 210], 'kidneys,': [11], 'prolonged': [13], 'physiological': [14], 'stress': [15], 'to': [16, 31, 66, 81, 134, 171, 230], 'and/or': [19], 'kidneys': [21, 181], 'can': [22, 235], 'cause': [23], 'adverse': [24], 'cardiorenal': [25, 49, 137, 156, 220], 'complications,': [26], 'including': [27], 'but': [28], 'not': [29], 'limited': [30], 'subclinical': [32], 'cardiomyopathy,': [33], 'failure': [35, 104, 123], 'chronic': [37, 111, 125], 'kidney': [38, 112, 126], 'disease.': [39, 127], 'Whilst': [40], 'more': [41, 232], 'common': [42], 'in': [43, 53, 69, 88, 100, 119, 164, 183, 222], 'individuals': [44], 'with': [45, 71, 90], 'Type': [46, 72, 93], '2': [47, 60, 73, 94], 'diabetes,': [48, 95], 'complications': [50], 'also': [51], 'occur': [52], 'absence': [55], 'of': [56, 108, 110, 121, 139, 147, 158, 175, 240], 'diabetes.': [57, 74], 'Sodium-glucose': [58], 'cotransporter': [59], 'inhibitors': [61], '(SGLT2i)': [62], 'were': [63], 'initially': [64], 'approved': [65], 'reduce': [67], 'hyperglycaemia': [68], 'patients': [70, 89, 233], 'Recently,': [75], 'these': [76, 162], 'agents': [77], 'have': [78, 131], 'been': [79, 132], 'shown': [80], 'significantly': [82], 'improve': [83], 'cardiovascular': [84], 'renal': [86, 152], 'outcomes': [87, 225], 'without': [92], 'demonstrating': [96], 'robust': [98], 'reduction': [99], 'hospitalisation': [101], 'for': [102, 117, 218], 'reduced': [106], 'risk': [107], 'progression': [109], 'disease,': [113], 'thus': [114], 'gaining': [115], 'approval': [116], 'use': [118, 239], 'treatment': [120], 'Numerous': [128], 'potential': [129, 149], 'mechanisms': [130, 153, 163, 169, 216], 'proposed': [133], 'explain': [135], 'effects': [138, 174], 'SGLT2i.': [140, 241], 'This': [141], 'review': [142], 'provides': [143], 'simplified': [145], 'summary': [146], 'key': [148], 'cardiac': [150, 212], 'underlying': [154], 'benefits': [157, 221], 'SGT2i': [159], 'explains': [161], 'clinical': [166, 173, 224], 'context.': [167], 'Key': [168], 'related': [170], 'SGLT2i': [176], 'on': [177, 189], 'explained': [182], 'this': [184], 'publication': [185], 'include': [186], 'their': [187], 'impact': [188], '(1)': [190], 'tissue': [191], 'oxygen': [192], 'delivery,': [193], 'hypoxia': [194], 'resultant': [196], 'ischaemic': [197], 'injury,': [198], '(2)': [199], 'vascular': [200], 'health': [201, 209], 'function,': [203], '(3)': [204], 'substrate': [205], 'utilisation': [206], 'metabolic': [208], '(4)': [211], 'remodelling.': [213], 'Knowing': [214], 'responsible': [217], 'SGLT2i-imparted': [219], 'will': [226], 'help': [227], 'healthcare': [228], 'practitioners': [229], 'identify': [231], 'that': [234], 'benefit': [236], 'from': [237]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4388538929', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2025-01-11T20:36:30.182326', 'created_date': '2023-11-10'}