Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4388458354', 'doi': 'https://doi.org/10.58837/chula.the.2016.1326', 'title': 'Differential expression of proteins in the central nervous system of early and late stage rabies infected dogs', 'display_name': 'Differential expression of proteins in the central nervous system of early and late stage rabies infected dogs', 'publication_year': 2016, 'publication_date': '2016-01-01', 'ids': {'openalex': 'https://openalex.org/W4388458354', 'doi': 'https://doi.org/10.58837/chula.the.2016.1326'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1326', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60789/1/5487838820.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'dissertation', 'type_crossref': 'dissertation', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60789/1/5487838820.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5071361127', 'display_name': 'Sangchai Yingsakmongkon', 'orcid': 'https://orcid.org/0000-0003-1535-1543'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Sangchai Yingsakmongkon', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5071361127'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11780', 'display_name': 'Rabies epidemiology and control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11780', 'display_name': 'Rabies epidemiology and control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11153', 'display_name': 'Streptococcal Infections and Treatments', 'score': 0.9861, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/proteome', 'display_name': 'Proteome', 'score': 0.64710987}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.4496008}], 'concepts': [{'id': 'https://openalex.org/C2776849203', 'wikidata': 'https://www.wikidata.org/wiki/Q39222', 'display_name': 'Rabies', 'level': 2, 'score': 0.8879092}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.65429485}, {'id': 'https://openalex.org/C104397665', 'wikidata': 'https://www.wikidata.org/wiki/Q860947', 'display_name': 'Proteome', 'level': 2, 'score': 0.64710987}, {'id': 'https://openalex.org/C2780775167', 'wikidata': 'https://www.wikidata.org/wiki/Q9606', 'display_name': 'Spinal cord', 'level': 2, 'score': 0.55561066}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5410918}, {'id': 'https://openalex.org/C551621295', 'wikidata': 'https://www.wikidata.org/wiki/Q182228', 'display_name': 'Brainstem', 'level': 2, 'score': 0.5337865}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.46256906}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.4496008}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.44277132}, {'id': 'https://openalex.org/C2777961786', 'wikidata': 'https://www.wikidata.org/wiki/Q698976', 'display_name': 'Rabies virus', 'level': 3, 'score': 0.4118409}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.32105303}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.30864125}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.28830644}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.20166963}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.1441173}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1326', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60789/1/5487838820.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.58837/chula.the.2016.1326', 'pdf_url': 'http://cuir.car.chula.ac.th/bitstream/123456789/60789/1/5487838820.pdf', 'source': None, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.63, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 88, 'referenced_works': ['https://openalex.org/W131624529', 'https://openalex.org/W1493120236', 'https://openalex.org/W1513603431', 'https://openalex.org/W1775749144', 'https://openalex.org/W1964687706', 'https://openalex.org/W1969296824', 'https://openalex.org/W1969905865', 'https://openalex.org/W1974132854', 'https://openalex.org/W1974139626', 'https://openalex.org/W1975809170', 'https://openalex.org/W1980087135', 'https://openalex.org/W1983217686', 'https://openalex.org/W1986678690', 'https://openalex.org/W1987516574', 'https://openalex.org/W1988852924', 'https://openalex.org/W1989658063', 'https://openalex.org/W1990138081', 'https://openalex.org/W1991683925', 'https://openalex.org/W1993363796', 'https://openalex.org/W2011298296', 'https://openalex.org/W2017230136', 'https://openalex.org/W2018275090', 'https://openalex.org/W2024241942', 'https://openalex.org/W2029439409', 'https://openalex.org/W2031748320', 'https://openalex.org/W2032972474', 'https://openalex.org/W2037465112', 'https://openalex.org/W2056182246', 'https://openalex.org/W2058192799', 'https://openalex.org/W2063457748', 'https://openalex.org/W2065638681', 'https://openalex.org/W2067786443', 'https://openalex.org/W2068062013', 'https://openalex.org/W2073079737', 'https://openalex.org/W2077179282', 'https://openalex.org/W2083214722', 'https://openalex.org/W2087614048', 'https://openalex.org/W2094503313', 'https://openalex.org/W2100837269', 'https://openalex.org/W2102133406', 'https://openalex.org/W2104550225', 'https://openalex.org/W2109243482', 'https://openalex.org/W2114688162', 'https://openalex.org/W2115994326', 'https://openalex.org/W2118108549', 'https://openalex.org/W2120243257', 'https://openalex.org/W2120528492', 'https://openalex.org/W2131991036', 'https://openalex.org/W2132155745', 'https://openalex.org/W2132786907', 'https://openalex.org/W2135136739', 'https://openalex.org/W2139343723', 'https://openalex.org/W2141344764', 'https://openalex.org/W2144785508', 'https://openalex.org/W2148894885', 'https://openalex.org/W2152736711', 'https://openalex.org/W2154078982', 'https://openalex.org/W2156799457', 'https://openalex.org/W2157002960', 'https://openalex.org/W2157096314', 'https://openalex.org/W2158080483', 'https://openalex.org/W2160443591', 'https://openalex.org/W2168113266', 'https://openalex.org/W2168963367', 'https://openalex.org/W2169330919', 'https://openalex.org/W2169915056', 'https://openalex.org/W2176414287', 'https://openalex.org/W2239597296', 'https://openalex.org/W2276034383', 'https://openalex.org/W2294516783', 'https://openalex.org/W2295826327', 'https://openalex.org/W2305581814', 'https://openalex.org/W2314210937', 'https://openalex.org/W2319171996', 'https://openalex.org/W2410554717', 'https://openalex.org/W2431048425', 'https://openalex.org/W2487691261', 'https://openalex.org/W2564483106', 'https://openalex.org/W2565603253', 'https://openalex.org/W2586676557', 'https://openalex.org/W2602934212', 'https://openalex.org/W2619405506', 'https://openalex.org/W4251909571', 'https://openalex.org/W4252262395', 'https://openalex.org/W46346130', 'https://openalex.org/W610636692', 'https://openalex.org/W67199098', 'https://openalex.org/W90724087'], 'related_works': ['https://openalex.org/W4390006636', 'https://openalex.org/W3165545267', 'https://openalex.org/W3150191817', 'https://openalex.org/W3088566151', 'https://openalex.org/W2374815345', 'https://openalex.org/W2160425225', 'https://openalex.org/W2061882794', 'https://openalex.org/W2056303242', 'https://openalex.org/W2021801449', 'https://openalex.org/W164495786'], 'abstract_inverted_index': {'Rabies': [0], 'is': [1, 52, 195], 'a': [2], 'zoonotic': [3], 'disease.': [4], 'Dogs': [5], 'are': [6, 22, 30], 'an': [7], 'important': [8], 'reservoir': [9], 'host': [10, 66], 'of': [11, 50, 79, 199, 218, 230, 237, 245], 'rabies': [12, 43, 51], 'in': [13, 25, 65, 68, 89, 142, 169, 182, 201, 209, 213, 234], 'Thailand,': [14], 'Asia,': [15], 'Africa': [16], 'and': [17, 27, 29, 36, 76, 104, 112, 122, 132, 164, 175, 192, 212, 215, 243], 'Europe.': [18], 'The': [19, 150], 'clinical': [20], 'manifestations': [21], 'the': [23, 46, 48, 196, 231], 'same': [24], 'humans': [26], 'dogs,': [28], 'categorized': [31], 'into': [32], '2': [33], 'forms;': [34], 'furious': [35, 93, 96], 'paralytic.': [37], 'Although': [38], 'there': [39], 'have': [40], 'been': [41], 'many': [42, 235], 'studies': [44], 'over': [45], 'years,': [47], 'pathogenesis': [49], 'still': [53], 'unclear.': [54], 'In': [55], 'this': [56], 'study,': [57], 'proteomic': [58], 'analysis': [59], 'was': [60], 'used': [61], 'to': [62, 82], 'investigate': [63], 'changes': [64, 200], 'responses': [67], 'central': [69], 'nervous': [70], 'system': [71], '(CNS)': [72], 'tissues': [73, 115, 131, 208], 'at': [74], 'early': [75, 92, 98, 214], 'late': [77, 95, 101, 216], 'stages': [78, 217], 'disease': [80], 'compared': [81], 'non-infected': [83], 'dog': [84], 'controls.': [85], 'They': [86, 179], 'were': [87, 120, 127, 152, 160], 'divided': [88], '5': [90, 118], 'groups;': [91], '(FE),': [94], '(FL),': [97], 'paralytic': [99, 102], '(DE),': [100], '(DL)': [103], 'control': [105], '(N),': [106], 'respectively.': [107, 178], 'Hippocampus,': [108], 'parietal': [109, 172], 'lobes,': [110, 173], 'brainstem': [111, 174], 'spinal': [113, 176], 'cord': [114], 'from': [116, 129, 205], 'these': [117, 130], 'groups': [119], 'collected': [121], 'stored': [123], 'until': [124], 'examination.': [125], 'Proteins': [126], 'extracted': [128], 'analyzed': [133], 'by': [134, 155], 'sodium': [135], 'dodecyl': [136], 'sulfate': [137], 'polyacrylamide': [138], 'gel': [139], 'electrophoresis': [140], '(SDS-PAGE)': [141], 'combination': [143], 'with': [144, 188], 'liquid': [145], 'chromatography': [146], 'mass': [147], 'spectrometry': [148], '(LC-MS/MS).': [149], 'proteins': [151, 166, 186], 'statistically': [153], 'selected': [154], 'suitable': [156], 'bioinformatics': [157], 'tools.': [158], 'There': [159], '26,': [161], '7,': [162], '35': [163], '18': [165], 'expressed': [167], 'only': [168, 227], 'each': [170], 'hippocampus,': [171], 'cord,': [177], 'played': [180], 'role': [181], 'cytoskeleton': [183], 'proteins,': [184], 'enzymes,': [185], 'associated': [187], 'cell': [189], 'death,': [190], 'inflammation': [191], 'immunity.': [193], 'This': [194, 220], 'first': [197], 'report': [198], 'proteome': [202], 'data': [203, 221], 'set': [204], 'rabies-infected': [206], 'CNS': [207, 238], 'both': [210], 'forms,': [211], 'infection.': [219], 'will': [222], 'be': [223], 'useful': [224], 'for': [225], 'not': [226], 'better': [228], 'understanding': [229], 'molecular': [232], 'mechanism': [233], 'regions': [236], 'tissues,': [239], 'but': [240], 'also': [241], 'diagnostic': [242], 'therapeutic': [244], 'rabies.': [246]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4388458354', 'counts_by_year': [], 'updated_date': '2024-12-14T04:28:41.260415', 'created_date': '2023-11-08'}