Abstract: Yanshan Zhu, MMed; Flávia Jacqueline Almeida, MD; J. Kenneth Baillie, PhD; Asha C. Bowen, PhD; Philip N. Britton, PhD; Martin Eduardo Brizuela, MD; Danilo Buonsenso, PhD; David Burgner, PhD; Keng Yih Chew, PhD; Kulkanya Chokephaibulkit, MD; Cheryl Cohen, PhD; Stephania A. Cormier, PhD; Nigel Crawford, PhD; Nigel Curtis, PhD; Camila G. A. Farias, MD; Charles F. Gilks, PhD; Anne von Gottberg, PhD; Diana Hamer, PhD; Daniel Jarovsky, MD; Waasila Jassat, PhD; Ana Rita Jesus, MD; Lisa S. Kemp, PhD; Benjawan Khumcha, MD; Georgina McCallum, BSc (Hons); Jessica E. Miller, PhD; Rosa Morello, PhD; Alasdair P. S. Munro, PhD; Peter J. M. Openshaw, PhD; Srivatsan Padmanabhan, MD, PhD; Wanatpreeya Phongsamart, MD; Gary Reubenson, FCPaed; Nicole Ritz, PhD; Fernanda Rodrigues, MD, PhD; Supattra Rungmaitree, MD; Fiona Russell, PhD; Marco A. P. Sáfadi, PhD; Christoph Saner, PhD; Malcolm G. Semple, PhD; Daniella Gregória Bomfim Prado da Silva, MD; Laíse Marine Moura de Sousa, MD; Marília Diogo Moço Souza, MD; Kirsten Spann, PhD; Sibongile Walaza, PhD; Nicole Wolter, PhD; Yao Xia, PhD; Daniel K. Yeoh, PhD; Heather J. Zar, PhD; Petra Zimmermann, PhD; Kirsty R. Short, PhD; International Severe Acute Respiratory and Emerging Infection Consortium Comprehensive Clinical Characterisation Collaboration (ISARIC4C) investigatorsPediatric Active Enhanced Disease Surveillance (PAEDS) Network group; Beatrice Alex; Petros Andrikopoulos; Benjamin Bach; Wendy S Barclay; Debby Bogaert; Meera Chand; Kanta Chechi; Graham S Cooke; Ana da Silva Filipe; Thushan de Silva; Annemarie B Docherty; Gonçalo dos Santos Correia; Marc-Emmanuel Dumas; Jake Dunning; Tom Fletcher; Christopher A Green; William Greenhalf; Julian Griffin; Rishi K Gupta; Ewen M Harrison; Antonia YW Ho; Karl Holden; Peter W Horby; Samreen Ijaz; Say Khoo; Paul Klenerman; Andrew Law; Matthew Lewis; Sonia Liggi; Wei Shen Lim; Lynn Maslen; Alexander J Mentzer; Laura Merson; Alison M Meynert; Shona C Moore; Mahdad Noursadeghi; Michael Olanipekun; Anthonia Osagie; Massimo Palmarini; Carlo Palmieri; William A Paxton; Georgios Pollakis; Nicholas Price; Andrew Rambaut; David L Robertson; Clark D Russell; Vanessa Sancho-Shimizu; Caroline Sands; Janet T Scott; Louise Sigfrid; Tom Solomon; Shiranee Sriskandan; David Stuart; Charlotte Summers; Olivia V Swann; Zoltan Takats; Panteleimon Takis; Richard S Tedder; AA Roger Thompson; Emma C Thomson; Ryan S Thwaites; Lance CW Turtle; Maria Zambon; Thomas M Drake; Cameron J Fairfield; Stephen R Knight; Kenneth A Mclean; Derek Murphy; Lisa Norman; Riinu Pius; Catherine A Shaw; Marie Connor; Jo Dalton; Carrol Gamble; Michelle Girvan; Sophie Halpin; Janet Harrison; Clare Jackson; James Lee; Laura Marsh; Daniel Plotkin; Stephanie Roberts; Egle Saviciute; Sara Clohisey; Ross Hendry; Susan Knight; Eva Lahnsteiner; Gary Leeming; Lucy Norris; James Scott-Brown; Sarah Tait; Murray Wham; Richard Clark; Audrey Coutts; Lorna Donelly; Angie Fawkes; Tammy Gilchrist; Katarzyna Hafezi; Louise MacGillivray; Alan Maclean; Sarah McCafferty; Kirstie Morrice; Lee Murphy; Nicola Wrobel; Gail Carson; Kayode Adeniji; Daniel Agranoff; Ken Agwuh; Dhiraj Ail; Erin L. Aldera; Ana Alegria; Sam Allen; Brian Angus; Abdul Ashish; Dougal Atkinson; Shahedal Bari; Gavin Barlow; Stella Barnass; Nicholas Barrett; Christopher Bassford; Sneha Basude; David Baxter; Michael Beadsworth; Jolanta Bernatoniene; John Berridge; Colin Berry; Nicola Best; Pieter Bothma; Robin Brittain-Long; Naomi Bulteel; Tom Burden; Andrew Burtenshaw; Vikki Caruth; David Chadwick; Duncan Chambler; Nigel Chee; Jenny Child; Srikanth Chukkambotla; Tom Clark; Paul Collini; Catherine Cosgrove; Jason Cupitt; Maria-Teresa Cutino-Moguel; Paul Dark; Chris Dawson; Samir Dervisevic; Phil Donnison; Sam Douthwaite; Andrew Drummond; Ingrid DuRand; Ahilanadan Dushianthan; Tristan Dyer; Cariad Evans; Chi Eziefula; Chrisopher Fegan; Adam Finn; Duncan Fullerton; Sanjeev Garg; Atul Garg; Effrossyni Gkrania-Klotsas; Jo Godden; Arthur Goldsmith; Clive Graham; Tassos Grammatikopoulos; Elaine Hardy; Stuart Hartshorn; Daniel Harvey; Peter Havalda; Daniel B Hawcutt; Maria Hobrok; Luke Hodgson; Anil Hormis; Joanne Howard; Michael Jacobs; Susan Jain; Paul Jennings; Agilan Kaliappan; Vidya Kasipandian; Stephen Kegg; Michael Kelsey; Jason Kendall; Caroline Kerrison; Ian Kerslake; Oliver Koch; Gouri Koduri; George Koshy; Shondipon Laha; Steven Laird; Susan Larkin; Tamas Leiner; Patrick Lillie; James Limb; Vanessa Linnett; Jeff Little; Mark Lyttle; Michael MacMahon; Emily MacNaughton; Ravish Mankregod; Huw Masson; Elijah Matovu; Katherine McCullough; Ruth McEwen; Manjula Meda; Gary Mills; Jane Minton; Kavya Mohandas; Quen Mok; James Moon; Elinoor Moore; Patrick Morgan; Craig Morris; Katherine Mortimore; Samuel Moses; Mbiye Mpenge; Rohinton Mulla; Michael Murphy; Thapas Nagarajan; Megan Nagel; Mark Nelson; Lillian Norris; Matthew K. O'Shea; Marlies Ostermann; Igor Otahal; Mark Pais; Selva Panchatsharam; Danai Papakonstantinou; Padmasayee Papineni; Hassan Paraiso; Brij Patel; Natalie Pattison; Justin Pepperell; Mark Peters; Mandeep Phull; Stefania Pintus; Tim Planche; Frank Post; David Price; Rachel Prout; Nikolas Rae; Henrik Reschreiter; Tim Reynolds; Neil Richardson; Mark Roberts; Devender Roberts; Alistair Rose; Guy Rousseau; Bobby Ruge; Brendan Ryan; Taranprit Saluja; Sarah Sarah; Matthias Schmid; Aarti Shah; Manu Shankar-Hari; Prad Shanmuga; Anil Sharma; Anna Shawcross; Jagtur Singh Pooni; Jeremy Sizer; Richard Smith; Catherine Snelson; Nick Spittle; Nikki Staines; Tom Stambach; Richard Stewart; Pradeep Subudhi; Tamas Szakmany; Kate Tatham; Jo Thomas; Chris Thompson; Robert Thompson; Ascanio Tridente; Darell Tupper-Carey; Mary Twagira; Nick Vallotton; Rama Vancheeswaran; Rachel Vincent ; Lisa Vincent-Smith; Shico Visuvanathan; Alan Vuylsteke; Sam Waddy; Rachel Wake; Andrew Walden; Ingeborg Welters; Tony Whitehouse; Paul Whittaker; Ashley Whittington; Meme Wijesinghe; Martin Williams; Lawrence Wilson; Stephen Winchester; Martin Wiselka; Adam Wolverson; Daniel G Wootton; Andrew Workman; Bryan Yates; Peter Young; Sarah E McDonald; Victoria Shaw; Katie A. Ahmed; Jane A Armstrong; Milton Ashworth; Innocent G Asiimwe; Siddharth Bakshi; Samantha L Barlow; Laura Booth; Benjamin Brennan; Katie Bullock; Nicola Carlucci ; Emily Cass; Benjamin WA Catterall; Jordan J Clark; Emily A Clarke; Sarah Cole; Louise Cooper; Helen Cox; Christopher Davis; Oslem Dincarslan; Alejandra Doce Carracedo; Chris Dunn; Philip Dyer; Angela Elliott; Anthony Evans; Lorna Finch; Lewis WS Fisher; Lisa Flaherty; Terry Foster; Isabel Garcia-Dorival; Philip Gunning; Catherine Hartley; Anthony Holmes; Rebecca L Jensen; Christopher B Jones; Trevor R Jones; Shadia Khandaker; Katharine King; Robyn T. Kiy; Chrysa Koukorava; Annette Lake; Suzannah Lant; Diane Latawiec; Lara Lavelle-Langham; Daniella Lefteri; Lauren Lett; Lucia A Livoti; Maria Mancini; Hannah Massey; Nicole Maziere; Sarah McDonald; Laurence McEvoy; John McLauchlan; Soeren Metelmann; Nahida S Miah; Joanna Middleton; Joyce Mitchell; Ellen G Murphy; Rebekah Penrice-Randal; Jack Pilgrim; Tessa Prince; Will Reynolds; P. Matthew Ridley; Debby Sales; Victoria E Shaw; Rebecca K Shears; Benjamin Small; Krishanthi S Subramaniam; Agnieska Szemiel; Aislynn Taggart; Jolanta Tanianis-Hughes; Jordan Thomas; Erwan Trochu; Libby van Tonder; Eve Wilcock; J. Eunice Zhang; Seán Keating; Cara Donegan; Rebecca G Spencer; Chloe Donohue; Fiona Griffiths; Hayley Hardwick; Wilna Oosthuyzen; Catherine Glover; Jeremy Carr; Julia Clark; Helen Marshall; Brendan McMullan; Joshua R. Francis; Christopher C. Blyth; Kristine Macartney; Emma Carey; Nicholas Wood; Jim Buttery; Nan Vasilunas; Elizabeth Elliott; Peter Richmond; Ushma Wadia; Alissa McMinn; Karen Bellamy; Guillian Hunter; Kathryn Meredith; Laura Rost; Nicole Kerly; Sonia Dougherty; Sara Cook; Natasha Doran; Laura Francis; Christine Heath; Carolyn Finucane