Title: Clinical effectiveness of islet transplantation
Abstract: Abstract Within the past 10 years, 329 new cases of adult islet allotransplantation and 145 cases of islet autotransplantation have been recorded by the International Islet Transplantation Registry [1]. Collectively, the results indicate that intrahepatic implantation of human islets can effectively replace the function of the endocrine pancreas and restore a near normal glucose homeostasis. However, clinical trials also show that the outcome of islet transplantation differs considerably depending on whether the graft is aimed at preventing or curing diabetes. Islet autotransplantation, performed to prevent diabetes in patients undergoing total pancreatectomy for painful chronic pancreatitis, restores normoglycaemia and independence from exogenous insulin administration in the majority of recipients [2].
Publication Year: 2002
Publication Date: 2002-04-18
Language: en
Type: book-chapter
Indexed In: ['crossref']
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