Abstract: Abstract Cryopreservation is the branch of cryobiology concerned with the maintenance or, more correctly, suspension of life during (prolonged) storage in the frozen state at ultralow temperatures. The fundamental principle of cryopreservation is that if the water inside a cell is converted to ice at temperatures low enough to effectively arrest molecular movement (freezing), the biochemical processes of cellular metabolism are suspended. Successful cryopreservation also requires that the biological system can be subsequently returned to normal temperatures (thawing) without sustaining biochemical or structural injuries that cause the cell to die. In the frozen state the cell is effectively in suspended animation.
Publication Year: 1994
Publication Date: 1994-01-06
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 10
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