Publication Information

{'id': 'https://openalex.org/W4387937397', 'doi': 'https://doi.org/10.3390/biom13111574', 'title': 'The Role of Exosome-Derived microRNA on Lung Cancer Metastasis Progression', 'display_name': 'The Role of Exosome-Derived microRNA on Lung Cancer Metastasis Progression', 'publication_year': 2023, 'publication_date': '2023-10-25', 'ids': {'openalex': 'https://openalex.org/W4387937397', 'doi': 'https://doi.org/10.3390/biom13111574', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/38002256'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/biom13111574', 'pdf_url': 'https://www.mdpi.com/2218-273X/13/11/1574/pdf?version=1698222569', 'source': {'id': 'https://openalex.org/S4210236520', 'display_name': 'Biomolecules', 'issn_l': '2218-273X', 'issn': ['2218-273X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2218-273X/13/11/1574/pdf?version=1698222569', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5002175692', 'display_name': 'Israel Martínez-Espinosa', 'orcid': 'https://orcid.org/0000-0002-6881-4655'}, 'institutions': [{'id': 'https://openalex.org/I4210102695', 'display_name': 'Instituto Nacional de Enfermedades Respiratorias', 'ror': 'https://ror.org/017fh2655', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I4210095685', 'https://openalex.org/I4210102695']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Israel Martinez-Espinosa', 'raw_affiliation_strings': ['Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico', 'institution_ids': ['https://openalex.org/I4210102695']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023449414', 'display_name': 'José A. Serrato', 'orcid': 'https://orcid.org/0000-0002-4252-2638'}, 'institutions': [{'id': 'https://openalex.org/I4210102695', 'display_name': 'Instituto Nacional de Enfermedades Respiratorias', 'ror': 'https://ror.org/017fh2655', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I4210095685', 'https://openalex.org/I4210102695']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'José Antonio Serrato', 'raw_affiliation_strings': ['Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico', 'institution_ids': ['https://openalex.org/I4210102695']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064874945', 'display_name': 'Blanca Ortíz-Quintero', 'orcid': 'https://orcid.org/0000-0001-6298-0073'}, 'institutions': [{'id': 'https://openalex.org/I4210102695', 'display_name': 'Instituto Nacional de Enfermedades Respiratorias', 'ror': 'https://ror.org/017fh2655', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I4210095685', 'https://openalex.org/I4210102695']}], 'countries': ['MX'], 'is_corresponding': True, 'raw_author_name': 'Blanca Ortiz-Quintero', 'raw_affiliation_strings': ['Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City CP 14080, Mexico', 'institution_ids': ['https://openalex.org/I4210102695']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5064874945'], 'corresponding_institution_ids': ['https://openalex.org/I4210102695'], 'apc_list': {'value': 2100, 'currency': 'CHF', 'value_usd': 2273, 'provenance': 'doaj'}, 'apc_paid': {'value': 2100, 'currency': 'CHF', 'value_usd': 2273, 'provenance': 'doaj'}, 'fwci': 0.969, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.999739, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '13', 'issue': '11', 'first_page': '1574', 'last_page': '1574'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10773', 'display_name': 'Extracellular vesicles in disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10773', 'display_name': 'Extracellular vesicles in disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/exosome', 'display_name': 'Exosome', 'score': 0.788105}, {'id': 'https://openalex.org/keywords/tumor-progression', 'display_name': 'Tumor progression', 'score': 0.6458562}], 'concepts': [{'id': 'https://openalex.org/C20518536', 'wikidata': 'https://www.wikidata.org/wiki/Q6840469', 'display_name': 'Microvesicles', 'level': 4, 'score': 0.90446794}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.82373863}, {'id': 'https://openalex.org/C2781261824', 'wikidata': 'https://www.wikidata.org/wiki/Q903634', 'display_name': 'Exosome', 'level': 5, 'score': 0.788105}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.7616081}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.6701379}, {'id': 'https://openalex.org/C555283112', 'wikidata': 'https://www.wikidata.org/wiki/Q1637543', 'display_name': 'Carcinogenesis', 'level': 3, 'score': 0.666771}, {'id': 'https://openalex.org/C2779256057', 'wikidata': 'https://www.wikidata.org/wiki/Q16909647', 'display_name': 'Tumor progression', 'level': 3, 'score': 0.6458562}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.56466544}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.5491691}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.49949694}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.43934798}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4204871}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.23080632}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.15496406}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.058376938}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055354', 'descriptor_name': 'Exosomes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009362', 'descriptor_name': 'Neoplasm Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/biom13111574', 'pdf_url': 'https://www.mdpi.com/2218-273X/13/11/1574/pdf?version=1698222569', 'source': {'id': 'https://openalex.org/S4210236520', 'display_name': 'Biomolecules', 'issn_l': '2218-273X', 'issn': ['2218-273X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669807', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/38002256', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/biom13111574', 'pdf_url': 'https://www.mdpi.com/2218-273X/13/11/1574/pdf?version=1698222569', 'source': {'id': 'https://openalex.org/S4210236520', 'display_name': 'Biomolecules', 'issn_l': '2218-273X', 'issn': ['2218-273X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.88, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 179, 'referenced_works': ['https://openalex.org/W1490568781', 'https://openalex.org/W1496604981', 'https://openalex.org/W1589968217', 'https://openalex.org/W1601681275', 'https://openalex.org/W1885450316', 'https://openalex.org/W1888498899', 'https://openalex.org/W1914130711', 'https://openalex.org/W1950118853', 'https://openalex.org/W1964631913', 'https://openalex.org/W1964847767', 'https://openalex.org/W1967615426', 'https://openalex.org/W1972381308', 'https://openalex.org/W1973188010', 'https://openalex.org/W1974608177', 'https://openalex.org/W1976324983', 'https://openalex.org/W1977666111', 'https://openalex.org/W1978401308', 'https://openalex.org/W1983116346', 'https://openalex.org/W1985844219', 'https://openalex.org/W1989603382', 'https://openalex.org/W1990741894', 'https://openalex.org/W1993913242', 'https://openalex.org/W1996863944', 'https://openalex.org/W1996997447', 'https://openalex.org/W2002516695', 'https://openalex.org/W2003343932', 'https://openalex.org/W2007663061', 'https://openalex.org/W2012295597', 'https://openalex.org/W2015312036', 'https://openalex.org/W2015541518', 'https://openalex.org/W2015994724', 'https://openalex.org/W2017044435', 'https://openalex.org/W2017246865', 'https://openalex.org/W2024492396', 'https://openalex.org/W2025199750', 'https://openalex.org/W2032735323', 'https://openalex.org/W2032945008', 'https://openalex.org/W2038236600', 'https://openalex.org/W2041433337', 'https://openalex.org/W2042759682', 'https://openalex.org/W2054925679', 'https://openalex.org/W2055313665', 'https://openalex.org/W2057332675', 'https://openalex.org/W2058689904', 'https://openalex.org/W2059615252', 'https://openalex.org/W2060133690', 'https://openalex.org/W2062206928', 'https://openalex.org/W2069372863', 'https://openalex.org/W2071361463', 'https://openalex.org/W2071925802', 'https://openalex.org/W2072109464', 'https://openalex.org/W2076424556', 'https://openalex.org/W2079449116', 'https://openalex.org/W2087324367', 'https://openalex.org/W2102707911', 'https://openalex.org/W2108248718', 'https://openalex.org/W2109691647', 'https://openalex.org/W2111698838', 'https://openalex.org/W2113860186', 'https://openalex.org/W2116921919', 'https://openalex.org/W2117692326', 'https://openalex.org/W2119043140', 'https://openalex.org/W2119764013', 'https://openalex.org/W2124422993', 'https://openalex.org/W2124803006', 'https://openalex.org/W2125120607', 'https://openalex.org/W2130687125', 'https://openalex.org/W2133521971', 'https://openalex.org/W2138664009', 'https://openalex.org/W2140690761', 'https://openalex.org/W2141196759', 'https://openalex.org/W2142239237', 'https://openalex.org/W2143600790', 'https://openalex.org/W2156323704', 'https://openalex.org/W2158903927', 'https://openalex.org/W2161199652', 'https://openalex.org/W2167809990', 'https://openalex.org/W2254833392', 'https://openalex.org/W2266814182', 'https://openalex.org/W2288482887', 'https://openalex.org/W2306957900', 'https://openalex.org/W2321170268', 'https://openalex.org/W2327541311', 'https://openalex.org/W2330004628', 'https://openalex.org/W2334059699', 'https://openalex.org/W2340514456', 'https://openalex.org/W2418074144', 'https://openalex.org/W2530674994', 'https://openalex.org/W2561123102', 'https://openalex.org/W2567639438', 'https://openalex.org/W2581841075', 'https://openalex.org/W2588432900', 'https://openalex.org/W2596133050', 'https://openalex.org/W2609243345', 'https://openalex.org/W2738491178', 'https://openalex.org/W2759574006', 'https://openalex.org/W2764338866', 'https://openalex.org/W2768132193', 'https://openalex.org/W2778617734', 'https://openalex.org/W2786514708', 'https://openalex.org/W2789345700', 'https://openalex.org/W2790666676', 'https://openalex.org/W2794825632', 'https://openalex.org/W2801850195', 'https://openalex.org/W2889646458', 'https://openalex.org/W2898610103', 'https://openalex.org/W2899500262', 'https://openalex.org/W2914525558', 'https://openalex.org/W2916210549', 'https://openalex.org/W2923685508', 'https://openalex.org/W2929491112', 'https://openalex.org/W2931418311', 'https://openalex.org/W2937327588', 'https://openalex.org/W2938403043', 'https://openalex.org/W2943993922', 'https://openalex.org/W2944216054', 'https://openalex.org/W2960044684', 'https://openalex.org/W2967761711', 'https://openalex.org/W2969197287', 'https://openalex.org/W2969330984', 'https://openalex.org/W2969856424', 'https://openalex.org/W2971173751', 'https://openalex.org/W2983881420', 'https://openalex.org/W2989955814', 'https://openalex.org/W3000076402', 'https://openalex.org/W3003526695', 'https://openalex.org/W3004047335', 'https://openalex.org/W3005104290', 'https://openalex.org/W3008596935', 'https://openalex.org/W3008654677', 'https://openalex.org/W3013831161', 'https://openalex.org/W3022472395', 'https://openalex.org/W3025440864', 'https://openalex.org/W3027029079', 'https://openalex.org/W3087276021', 'https://openalex.org/W3099731034', 'https://openalex.org/W3106494191', 'https://openalex.org/W3106806530', 'https://openalex.org/W3117667198', 'https://openalex.org/W3121104869', 'https://openalex.org/W3127032572', 'https://openalex.org/W3131032505', 'https://openalex.org/W3131235172', 'https://openalex.org/W3135072380', 'https://openalex.org/W3159022204', 'https://openalex.org/W3165413311', 'https://openalex.org/W3166942010', 'https://openalex.org/W3182387014', 'https://openalex.org/W3184310928', 'https://openalex.org/W3188277569', 'https://openalex.org/W318955610', 'https://openalex.org/W3197796049', 'https://openalex.org/W3197901743', 'https://openalex.org/W3199260936', 'https://openalex.org/W3200993627', 'https://openalex.org/W3201325011', 'https://openalex.org/W3204229687', 'https://openalex.org/W3205011643', 'https://openalex.org/W4200369104', 'https://openalex.org/W4200449126', 'https://openalex.org/W4206243212', 'https://openalex.org/W4210516674', 'https://openalex.org/W4211032048', 'https://openalex.org/W4211260961', 'https://openalex.org/W4224281610', 'https://openalex.org/W4224879863', 'https://openalex.org/W4284973628', 'https://openalex.org/W4292856186', 'https://openalex.org/W4293105698', 'https://openalex.org/W4294152366', 'https://openalex.org/W4300963290', 'https://openalex.org/W4306311488', 'https://openalex.org/W4311431206', 'https://openalex.org/W4311669536', 'https://openalex.org/W4321210045', 'https://openalex.org/W4323851116', 'https://openalex.org/W4375858548', 'https://openalex.org/W4378516548', 'https://openalex.org/W933792315'], 'related_works': ['https://openalex.org/W4387637728', 'https://openalex.org/W4386033707', 'https://openalex.org/W4321166613', 'https://openalex.org/W2947838112', 'https://openalex.org/W2896759930', 'https://openalex.org/W2529223554', 'https://openalex.org/W2111545764', 'https://openalex.org/W2073341747', 'https://openalex.org/W2067275497', 'https://openalex.org/W1970650594'], 'abstract_inverted_index': {'The': [0], 'high': [1], 'mortality': [2], 'from': [3], 'lung': [4, 25, 123, 146, 178], 'cancer': [5, 26, 147], 'is': [6, 132], 'mainly': [7], 'attributed': [8], 'to': [9, 74], 'the': [10, 15, 21, 28, 60, 93], 'presence': [11], 'of': [12, 17, 24, 96, 104], 'metastases': [13], 'at': [14], 'time': [16], 'diagnosis.': [18], 'Despite': [19], 'being': [20], 'leading': [22], 'cause': [23], 'death,': [27], 'underlying': [29], 'molecular': [30], 'mechanisms': [31], 'driving': [32], 'metastasis': [33, 81, 121, 154, 173], 'progression': [34, 53, 119, 174], 'are': [35, 112, 115], 'still': [36, 133], 'not': [37], 'fully': [38], 'understood.': [39], 'Recent': [40], 'studies': [41], 'suggest': [42], 'that': [43, 68], 'tumor': [44, 52, 58, 118], 'cell': [45], 'exosomes': [46, 69], 'play': [47], 'a': [48, 90, 101, 142], 'significant': [49], 'role': [50, 171], 'in': [51, 106, 122, 134, 172], 'through': [54], 'intercellular': [55], 'communication': [56], 'between': [57], 'cells,': [59], 'microenvironment,': [61], 'and': [62, 77, 86, 120], 'distant': [63, 75], 'organs.': [64], 'Furthermore,': [65], 'evidence': [66, 157], 'shows': [67], 'release': [70], 'biologically': [71], 'active': [72, 94], 'components': [73, 95, 111], 'sites': [76], 'organs,': [78], 'which': [79, 114], 'direct': [80], 'by': [82], 'preparing': [83], 'metastatic': [84], 'pre-niche': [85], 'stimulating': [87], 'tumorigenesis.': [88], 'As': [89], 'result,': [91], 'identifying': [92], 'exosome': [97], 'cargo': [98], 'has': [99], 'become': [100], 'critical': [102], 'area': [103], 'research': [105, 126, 167], 'recent': [107], 'years.': [108], 'Among': [109], 'these': [110], 'microRNAs,': [113], 'associated': [116], 'with': [117], 'cancer.': [124, 179], 'Although': [125], 'into': [127], 'exosome-derived': [128], 'microRNA': [129], '(exosomal': [130], 'miRNAs)': [131], 'its': [135], 'early': [136], 'stages,': [137], 'it': [138], 'holds': [139], 'promise': [140], 'as': [141], 'potential': [143], 'target': [144], 'for': [145, 158], 'therapy.': [148], 'Understanding': [149], 'how': [150], 'exosomal': [151, 169], 'microRNAs': [152], 'promote': [153], 'will': [155], 'provide': [156], 'developing': [159], 'new': [160], 'targeted': [161], 'treatments.': [162], 'This': [163], 'review': [164], 'summarizes': [165], 'current': [166], 'on': [168, 177], 'miRNAs’': [170], 'mechanisms,': [175], 'focusing': [176]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4387937397', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-19T06:33:50.946168', 'created_date': '2023-10-26'}