Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4387169766', 'doi': 'https://doi.org/10.1007/s11010-023-04847-4', 'title': 'YAP1 inhibits RSL3-induced castration-resistant prostate cancer cell ferroptosis by driving glutamine uptake and metabolism to GSH', 'display_name': 'YAP1 inhibits RSL3-induced castration-resistant prostate cancer cell ferroptosis by driving glutamine uptake and metabolism to GSH', 'publication_year': 2023, 'publication_date': '2023-09-29', 'ids': {'openalex': 'https://openalex.org/W4387169766', 'doi': 'https://doi.org/10.1007/s11010-023-04847-4', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37773303'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s11010-023-04847-4', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s11010-023-04847-4.pdf', 'source': {'id': 'https://openalex.org/S11742566', 'display_name': 'Molecular and Cellular Biochemistry', 'issn_l': '0300-8177', 'issn': ['0300-8177', '1573-4919'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://link.springer.com/content/pdf/10.1007/s11010-023-04847-4.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033503300', 'display_name': 'Xian Fu', 'orcid': 'https://orcid.org/0000-0002-7982-1092'}, 'institutions': [{'id': 'https://openalex.org/I4210148790', 'display_name': "Hangzhou First People's Hospital", 'ror': 'https://ror.org/05pwsw714', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148790']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xian Fu', 'raw_affiliation_strings': ["Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"], 'affiliations': [{'raw_affiliation_string': "Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China", 'institution_ids': ['https://openalex.org/I4210148790', 'https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112570727', 'display_name': 'Hongshen Wu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210148790', 'display_name': "Hangzhou First People's Hospital", 'ror': 'https://ror.org/05pwsw714', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148790']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongshen Wu', 'raw_affiliation_strings': ["Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"], 'affiliations': [{'raw_affiliation_string': "Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China", 'institution_ids': ['https://openalex.org/I4210148790', 'https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100357435', 'display_name': 'Chang‐Jiu Li', 'orcid': 'https://orcid.org/0000-0001-9814-064X'}, 'institutions': [{'id': 'https://openalex.org/I4210148790', 'display_name': "Hangzhou First People's Hospital", 'ror': 'https://ror.org/05pwsw714', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148790']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Changjiu Li', 'raw_affiliation_strings': ["Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"], 'affiliations': [{'raw_affiliation_string': "Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China", 'institution_ids': ['https://openalex.org/I4210148790', 'https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101474968', 'display_name': 'Gang Deng', 'orcid': 'https://orcid.org/0000-0003-2382-6297'}, 'institutions': [{'id': 'https://openalex.org/I4210148790', 'display_name': "Hangzhou First People's Hospital", 'ror': 'https://ror.org/05pwsw714', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148790']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Gang Deng', 'raw_affiliation_strings': ["Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"], 'affiliations': [{'raw_affiliation_string': "Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China", 'institution_ids': ['https://openalex.org/I4210148790', 'https://openalex.org/I76130692']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100408328', 'display_name': 'Chao Chen', 'orcid': 'https://orcid.org/0000-0001-9689-2143'}, 'institutions': [{'id': 'https://openalex.org/I4210148790', 'display_name': "Hangzhou First People's Hospital", 'ror': 'https://ror.org/05pwsw714', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148790']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chao Chen', 'raw_affiliation_strings': ["Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"], 'affiliations': [{'raw_affiliation_string': "Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China", 'institution_ids': ['https://openalex.org/I4210148790', 'https://openalex.org/I76130692']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.48, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.999876, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 88, 'max': 91}, 'biblio': {'volume': '479', 'issue': '9', 'first_page': '2415', 'last_page': '2427'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12465', 'display_name': 'Cancer, Lipids, and Metabolism', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12465', 'display_name': 'Cancer, Lipids, and Metabolism', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11297', 'display_name': 'Ferroptosis and cancer prognosis', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779349466', 'wikidata': 'https://www.wikidata.org/wiki/Q181619', 'display_name': 'Glutamine', 'level': 3, 'score': 0.6894657}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.62909794}, {'id': 'https://openalex.org/C382228', 'wikidata': 'https://www.wikidata.org/wiki/Q849994', 'display_name': 'Clinical chemistry', 'level': 2, 'score': 0.6143847}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.5984213}, {'id': 'https://openalex.org/C538909803', 'wikidata': 'https://www.wikidata.org/wiki/Q116907', 'display_name': 'Glutathione', 'level': 3, 'score': 0.5353563}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.53197926}, {'id': 'https://openalex.org/C2776235491', 'wikidata': 'https://www.wikidata.org/wiki/Q9625', 'display_name': 'Prostate', 'level': 3, 'score': 0.5203785}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.46005175}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.44900638}, {'id': 'https://openalex.org/C2779256933', 'wikidata': 'https://www.wikidata.org/wiki/Q58929', 'display_name': 'Castration', 'level': 3, 'score': 0.4441228}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.43888244}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36569422}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.19799769}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.082814336}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.07633561}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D048868', 'descriptor_name': 'Adaptor Proteins, Signal Transducing', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D026962', 'descriptor_name': 'Amino Acid Transport System ASC', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002243', 'descriptor_name': 'Carbolines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000079403', 'descriptor_name': 'Ferroptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005972', 'descriptor_name': 'Glutaminase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005973', 'descriptor_name': 'Glutamine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005978', 'descriptor_name': 'Glutathione', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015778', 'descriptor_name': 'Minor Histocompatibility Antigens', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009363', 'descriptor_name': 'Neoplasm Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000091102', 'descriptor_name': 'YAP-Signaling Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s11010-023-04847-4', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s11010-023-04847-4.pdf', 'source': {'id': 'https://openalex.org/S11742566', 'display_name': 'Molecular and Cellular Biochemistry', 'issn_l': '0300-8177', 'issn': ['0300-8177', '1573-4919'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37773303', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/s11010-023-04847-4', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/s11010-023-04847-4.pdf', 'source': {'id': 'https://openalex.org/S11742566', 'display_name': 'Molecular and Cellular Biochemistry', 'issn_l': '0300-8177', 'issn': ['0300-8177', '1573-4919'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.55}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W2112413714', 'https://openalex.org/W2137785594', 'https://openalex.org/W2220221033', 'https://openalex.org/W2244948668', 'https://openalex.org/W2534904302', 'https://openalex.org/W2727828415', 'https://openalex.org/W2767055857', 'https://openalex.org/W2771792762', 'https://openalex.org/W2771794752', 'https://openalex.org/W2781725704', 'https://openalex.org/W2794021749', 'https://openalex.org/W2890361765', 'https://openalex.org/W2890668604', 'https://openalex.org/W2913768244', 'https://openalex.org/W2964069817', 'https://openalex.org/W2966798736', 'https://openalex.org/W2967986110', 'https://openalex.org/W2977811794', 'https://openalex.org/W2978011336', 'https://openalex.org/W2979937337', 'https://openalex.org/W2982617652', 'https://openalex.org/W2996461479', 'https://openalex.org/W3003960907', 'https://openalex.org/W3010570086', 'https://openalex.org/W3011593838', 'https://openalex.org/W3012682077', 'https://openalex.org/W3015495450', 'https://openalex.org/W3027500407', 'https://openalex.org/W3029915591', 'https://openalex.org/W3099638044', 'https://openalex.org/W3121196410', 'https://openalex.org/W3124284550', 'https://openalex.org/W3128646645', 'https://openalex.org/W3129721110', 'https://openalex.org/W3132483266', 'https://openalex.org/W3135094294', 'https://openalex.org/W3135405660', 'https://openalex.org/W3146001933', 'https://openalex.org/W3182510947', 'https://openalex.org/W4205897669', 'https://openalex.org/W4282959566', 'https://openalex.org/W4286253973', 'https://openalex.org/W4297087537', 'https://openalex.org/W4312113152', 'https://openalex.org/W4317435527', 'https://openalex.org/W4322102410'], 'related_works': ['https://openalex.org/W4313436117', 'https://openalex.org/W2993729724', 'https://openalex.org/W2944924574', 'https://openalex.org/W2883402525', 'https://openalex.org/W2557196417', 'https://openalex.org/W2418637534', 'https://openalex.org/W2157439642', 'https://openalex.org/W2114085849', 'https://openalex.org/W2018967970', 'https://openalex.org/W1978459015'], 'abstract_inverted_index': {'High': [0], 'levels': [1, 39, 146, 175], 'of': [2, 40, 105, 126, 139, 147, 158, 166, 190, 195, 214], 'YAP1': [3, 25, 73, 106, 118, 143, 162, 191, 202], 'and': [4, 16, 31, 43, 59, 70, 85, 96, 114, 123, 128, 131, 152, 155, 168, 170, 176, 210, 216, 223, 228, 239], 'ferroptosis': [5, 27, 109, 140, 194], 'activation': [6, 138], 'in': [7, 28, 45, 111], 'castration-resistant': [8], 'prostate': [9, 50], 'cancer': [10, 51], '(CRPC)': [11], 'can': [12], 'inhibit': [13], 'CRPC': [14, 29, 60, 112, 197], 'progression': [15], 'improve': [17], 'its': [18, 115], 'sensitivity': [19], 'toward': [20], 'chemotherapeutics': [21], 'drugs.': [22], 'However,': [23], 'whether': [24], 'regulates': [26], 'cells': [30, 113], 'the': [32, 103, 108, 133, 137, 145, 156, 164, 173, 187, 193, 201, 208, 212], 'underlying': [33, 116], 'mechanisms': [34], 'are': [35], 'unknown.': [36], 'The': [37], 'protein': [38], 'YAP1,': [41], 'SLC1A5,': [42], 'GLS1': [44, 169, 183], 'benign': [46], 'prostatic': [47], 'hyperplasia': [48], '(BPH),': [49], '(PCa)': [52], 'that': [53], 'did': [54], 'not': [55], 'progress': [56], 'to': [57, 101, 225], 'CRPC,': [58, 200], 'tissue': [61], 'samples': [62], 'were': [63, 88, 99], 'evaluated': [64], 'using': [65], 'western': [66], 'blotting.': [67], 'In': [68, 199], 'PC-3': [69], 'DU-145': [71], 'cells,': [72], 'overexpression': [74], 'vector,': [75], 'small-interfering': [76], 'RNA,': [77], 'specific': [78], 'inhibitor': [79], 'verteporfin,': [80], 'ferroptosis-inducer': [81], 'RSL3,': [82, 142], 'SLC1A5-inhibitor': [83], 'V-9302,': [84], 'GLS1-inhibitor': [86], 'CB-839': [87], 'used.': [89], 'Immunofluorescence,': [90], 'flow': [91], 'cytometry,': [92], 'dual-luciferase': [93], 'reporter': [94], 'gene,': [95], 'related': [97], 'kits': [98], 'used': [100], 'investigate': [102], 'effect': [104, 189], 'on': [107, 192], 'activity': [110, 184], 'mechanisms.': [117], 'promoted': [119, 163], 'extracellular': [120], 'glutamine': [121, 221], 'uptake': [122, 222], 'subsequent': [124], 'production': [125], 'glutamate': [127, 227], 'glutathione': [129], '(GSH),': [130], 'increases': [132], 'GPX4': [134, 177, 233], 'activity.': [135, 178], 'For': [136], 'by': [141], 'decreased': [144], 'reactive': [148], 'oxygen': [149], 'species,': [150], 'malondialdehyde,': [151], 'lipid': [153], 'peroxidation,': [154], 'proportion': [157], 'dead': [159], 'cells.': [160, 198], 'Mechanistically,': [161], 'expression': [165], 'SCL1A5': [167], 'further': [171, 229], 'increased': [172], 'GSH': [174], 'Thus,': [179], 'inhibiting': [180, 240], 'SLC1A5': [181, 215], 'or': [182], 'could': [185], 'alleviate': [186], 'antagonistic': [188], 'RSL3-induced': [196], 'level': [203], 'is': [204], 'high,': [205], 'which': [206], 'enters': [207], 'nucleus': [209], 'promotes': [211], 'expressions': [213], 'GLS1,': [217], 'thereby': [218], 'promoting': [219], 'cellular': [220, 236], 'metabolism': [224], 'generate': [226], 'synthesizing': [230], 'GSH,': [231], 'increasing': [232], 'activity,': [234], 'improving': [235], 'antioxidant': [237], 'capacity,': [238], 'cell': [241], 'death.': [242]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4387169766', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-15T16:42:46.785509', 'created_date': '2023-09-30'}