Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4385751324', 'doi': 'https://doi.org/10.1111/all.15841', 'title': 'β‐1,3‐glucan, but not β‐1,3/1,6‐glucan, exacerbates experimental food allergy, while both increase <scp>IgA</scp> induction', 'display_name': 'β‐1,3‐glucan, but not β‐1,3/1,6‐glucan, exacerbates experimental food allergy, while both increase <scp>IgA</scp> induction', 'publication_year': 2023, 'publication_date': '2023-08-11', 'ids': {'openalex': 'https://openalex.org/W4385751324', 'doi': 'https://doi.org/10.1111/all.15841', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37565258'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/all.15841', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.15841', 'source': {'id': 'https://openalex.org/S68090385', 'display_name': 'Allergy', 'issn_l': '0105-4538', 'issn': ['0105-4538', '1398-9995'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.15841', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047781708', 'display_name': 'Chaoqi He', 'orcid': 'https://orcid.org/0000-0003-2900-9431'}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Chaoqi He', 'raw_affiliation_strings': ['Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100731398', 'display_name': 'Yunhui Liu', 'orcid': 'https://orcid.org/0000-0001-7282-834X'}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yunhui Liu', 'raw_affiliation_strings': ['Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039122343', 'display_name': 'Stefan Schülke', 'orcid': 'https://orcid.org/0000-0002-9674-5116'}, 'institutions': [{'id': 'https://openalex.org/I884002606', 'display_name': 'Paul Ehrlich Institut', 'ror': 'https://ror.org/00yssnc44', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I884002606']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stefan Schülke', 'raw_affiliation_strings': ['Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany', 'institution_ids': ['https://openalex.org/I884002606']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078888307', 'display_name': 'Shunsuke Nishio', 'orcid': 'https://orcid.org/0000-0003-3420-2578'}, 'institutions': [{'id': 'https://openalex.org/I58089638', 'display_name': 'Fukushima University', 'ror': 'https://ror.org/03zjb7z20', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I58089638']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shunsuke Nishio', 'raw_affiliation_strings': ['Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan', 'institution_ids': ['https://openalex.org/I58089638']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102511084', 'display_name': 'Guo Ying-nan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yingnan Guo', 'raw_affiliation_strings': ['Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051884500', 'display_name': 'Hannah Rainer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I884002606', 'display_name': 'Paul Ehrlich Institut', 'ror': 'https://ror.org/00yssnc44', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I884002606']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hannah Rainer', 'raw_affiliation_strings': ['Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany', 'institution_ids': ['https://openalex.org/I884002606']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5092627589', 'display_name': 'Krause Maren', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I884002606', 'display_name': 'Paul Ehrlich Institut', 'ror': 'https://ror.org/00yssnc44', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I884002606']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Krause Maren', 'raw_affiliation_strings': ['Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany', 'institution_ids': ['https://openalex.org/I884002606']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018725079', 'display_name': 'Ting‐Yu Cheng', 'orcid': 'https://orcid.org/0000-0002-3732-9147'}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ting‐Yu Cheng', 'raw_affiliation_strings': ['Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032495081', 'display_name': 'Tomonori Nochi', 'orcid': 'https://orcid.org/0000-0003-1800-6972'}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomonori Nochi', 'raw_affiliation_strings': ['Laboratory of Animal Functional Morphology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Animal Functional Morphology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026230972', 'display_name': 'Stefan Vieths', 'orcid': 'https://orcid.org/0000-0003-3826-6704'}, 'institutions': [{'id': 'https://openalex.org/I884002606', 'display_name': 'Paul Ehrlich Institut', 'ror': 'https://ror.org/00yssnc44', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I884002606']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stefan Vieths', 'raw_affiliation_strings': ['Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany', 'institution_ids': ['https://openalex.org/I884002606']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019714610', 'display_name': 'Stephan Scheurer', 'orcid': 'https://orcid.org/0000-0002-2859-562X'}, 'institutions': [{'id': 'https://openalex.org/I884002606', 'display_name': 'Paul Ehrlich Institut', 'ror': 'https://ror.org/00yssnc44', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I884002606']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stephan Scheurer', 'raw_affiliation_strings': ['Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Allergology, Paul-Ehrlich-Institut, Langen, Germany', 'institution_ids': ['https://openalex.org/I884002606']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031625403', 'display_name': 'Tsukasa Matsuda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I58089638', 'display_name': 'Fukushima University', 'ror': 'https://ror.org/03zjb7z20', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I58089638']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tsukasa Matsuda', 'raw_affiliation_strings': ['Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan', 'institution_ids': ['https://openalex.org/I58089638']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066736622', 'display_name': 'Masako Toda', 'orcid': 'https://orcid.org/0000-0002-7273-9977'}, 'institutions': [{'id': 'https://openalex.org/I201537933', 'display_name': 'Tohoku University', 'ror': 'https://ror.org/01dq60k83', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201537933']}, {'id': 'https://openalex.org/I58089638', 'display_name': 'Fukushima University', 'ror': 'https://ror.org/03zjb7z20', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I58089638']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Masako Toda', 'raw_affiliation_strings': ['Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan', 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan', 'institution_ids': ['https://openalex.org/I201537933']}, {'raw_affiliation_string': 'Faculty of Food and Agricultural Sciences, Institute of Fermentation Sciences (IFeS), Fukushima University, Fukushima, Japan', 'institution_ids': ['https://openalex.org/I58089638']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5066736622'], 'corresponding_institution_ids': ['https://openalex.org/I201537933', 'https://openalex.org/I58089638'], 'apc_list': {'value': 4900, 'currency': 'USD', 'value_usd': 4900, 'provenance': 'doaj'}, 'apc_paid': {'value': 4900, 'currency': 'USD', 'value_usd': 4900, 'provenance': 'doaj'}, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.561644, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 88}, 'biblio': {'volume': '79', 'issue': '2', 'first_page': '503', 'last_page': '506'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10869', 'display_name': 'Polysaccharides and Plant Cell Walls', 'score': 0.9878, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10869', 'display_name': 'Polysaccharides and Plant Cell Walls', 'score': 0.9878, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10365', 'display_name': 'Gastrointestinal motility and disorders', 'score': 0.9809, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13199', 'display_name': 'Digestive system and related health', 'score': 0.9785, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2776123893', 'wikidata': 'https://www.wikidata.org/wiki/Q416796', 'display_name': 'Glucan', 'level': 2, 'score': 0.8255444}, {'id': 'https://openalex.org/C207480886', 'wikidata': 'https://www.wikidata.org/wiki/Q42982', 'display_name': 'Allergy', 'level': 2, 'score': 0.63816696}, {'id': 'https://openalex.org/C2780510475', 'wikidata': 'https://www.wikidata.org/wiki/Q186752', 'display_name': 'Allergen', 'level': 3, 'score': 0.5537358}, {'id': 'https://openalex.org/C2776027960', 'wikidata': 'https://www.wikidata.org/wiki/Q769815', 'display_name': 'Food allergy', 'level': 3, 'score': 0.5463569}, {'id': 'https://openalex.org/C141105273', 'wikidata': 'https://www.wikidata.org/wiki/Q79455', 'display_name': 'Immunoglobulin E', 'level': 3, 'score': 0.5327423}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.52946275}, {'id': 'https://openalex.org/C2777863537', 'wikidata': 'https://www.wikidata.org/wiki/Q357896', 'display_name': 'Adjuvant', 'level': 2, 'score': 0.4795277}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.43588698}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.34333143}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33553496}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1821334}], 'mesh': [{'descriptor_ui': 'D005512', 'descriptor_name': 'Food Hypersensitivity', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D005936', 'descriptor_name': 'Glucans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007070', 'descriptor_name': 'Immunoglobulin A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047071', 'descriptor_name': 'beta-Glucans', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/all.15841', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.15841', 'source': {'id': 'https://openalex.org/S68090385', 'display_name': 'Allergy', 'issn_l': '0105-4538', 'issn': ['0105-4538', '1398-9995'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37565258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/all.15841', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.15841', 'source': {'id': 'https://openalex.org/S68090385', 'display_name': 'Allergy', 'issn_l': '0105-4538', 'issn': ['0105-4538', '1398-9995'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.55, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [{'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 6, 'referenced_works': ['https://openalex.org/W1982189917', 'https://openalex.org/W2002611996', 'https://openalex.org/W2409656339', 'https://openalex.org/W2742698252', 'https://openalex.org/W3153167584', 'https://openalex.org/W3172216030'], 'related_works': ['https://openalex.org/W4251003423', 'https://openalex.org/W2944387023', 'https://openalex.org/W2892370718', 'https://openalex.org/W2770267399', 'https://openalex.org/W2419002337', 'https://openalex.org/W2411933361', 'https://openalex.org/W2386116568', 'https://openalex.org/W2378135797', 'https://openalex.org/W2349441096', 'https://openalex.org/W2006108005'], 'abstract_inverted_index': {'Dietary': [0], 'fiber': [1, 552], 'has': [2, 17, 602], 'gained': [3], 'interest': [4], 'as': [5, 41, 587], 'a': [6, 42, 57, 63, 117, 151, 307, 334, 414], 'prebiotic': [7], 'to': [8, 56, 137, 150, 189, 438, 514, 535, 556, 603, 798], 'treat': [9], 'allergy.1': [10], 'However,': [11, 478], 'the': [12, 22, 33, 102, 108, 129, 166, 203, 247, 252, 257, 267, 275, 283, 291, 312, 318, 343, 379, 405, 419, 426, 439, 479, 482, 493, 504, 515, 520, 540, 550, 684, 691, 696, 753, 761, 777, 787, 799, 803], 'immunomodulatory': [13, 470], 'function': [14], 'of': [15, 35, 104, 132, 165, 216, 231, 243, 249, 266, 285, 314, 320, 327, 348, 366, 381, 407, 416, 421, 434, 469, 481, 484, 539, 575, 578, 583, 594, 638, 648, 714, 728, 733, 743, 755, 781], 'β-glucan': [16, 126, 258, 527], 'been': [18], 'debated.2,': [19], '3': [20], 'In': [21, 196, 519], 'present': [23], 'study,': [24], 'we': [25], 'found': [26], 'evidence': [27], 'that': [28, 159, 187, 202, 270, 356, 401, 503, 565, 751], '(i)': [29], 'β-1,3-glucan': [30, 69, 95, 145, 172, 188, 212, 298, 315, 349, 357, 402, 435, 443, 460, 508, 584, 639], 'may': [31, 436], 'exacerbate': [32], 'development': [34, 103, 319, 380], 'food': [36, 118, 566], 'allergy,': [37], 'but': [38, 55, 97, 135, 331, 447, 580], 'also': [39, 50, 581], 'act': [40], 'mucosal': [43, 161, 363, 588], 'adjuvant': [44, 53, 192, 368, 597], 'increasing': [45], 'IgA,': [46, 158], 'and': [47, 76, 85, 87, 92, 107, 147, 156, 176, 209, 220, 246, 259, 288, 296, 304, 329, 374, 376, 392, 418, 424, 428, 444, 458, 465, 488, 585, 599, 609, 615, 622, 646, 655, 673, 680, 689, 709], '(ii)': [48], 'β-1,3/1,6-glucan': [49, 99, 148, 227, 445, 586], 'possesses': [51], 'an': [52], 'effect,': [54, 369], 'lesser': [58, 152], 'extent': [59], 'than': [60, 184, 549, 792], 'β-1,3-glucan,': [61, 579], 'using': [62], 'murine': [64], 'model': [65, 120], '(Figure': [66, 121, 140, 168, 194, 237, 262, 278, 300, 323, 351, 430, 476, 496], 'S1A).': [67], 'Linear': [68], 'backbones': [70], 'with': [71, 114, 590, 596, 662], 'β-1,6-linked': [72], 'side': [73, 78], 'chains': [74, 79], '(β-1,3/1,6-glucan)': [75], 'without': [77], '(β-1,3-glucan)': [80], 'are': [81, 88, 737, 758], 'isolated': [82], 'from': [83, 179, 211, 226, 389, 554, 760], 'yeast': [84], 'fungi,': [86], 'ligands': [89], 'binding': [90], 'TLR2': [91], 'Dectin-1.2': [93], 'Surprisingly,': [94], 'diet,': [96, 100, 146], 'not': [98, 332, 448, 511, 774], 'promoted': [101], 'allergic': [105, 119, 321, 382, 517, 567], 'diarrhea': [106, 322], 'drop': [109], 'in': [110, 116, 163, 235, 251, 290, 294, 345, 362, 397, 425, 454, 529, 542, 559, 739, 746], 'body': [111], 'temperature': [112], 'associated': [113], 'anaphylaxis': [115], '1A;': [122], 'Figure': [123, 142, 170, 239, 280, 498], 'S1B).': [124], 'Neither': [125], 'diet': [127, 149, 273, 316, 403, 461, 509, 528], 'enhanced': [128, 214, 229, 440, 516], 'serum': [130], 'levels': [131, 242, 420, 480], 'allergen-specific': [133, 157], 'IgE,': [134], 'tended': [136], 'reduce': [138], 'IgG2a': [139], '1B;': [141], 'S1C).': [143], 'Notably,': [144], 'extent,': [153], 'increased': [154, 293, 404, 462], 'total': [155], 'is,': [160], 'antibodies,': [162], 'feces': [164], 'mice': [167, 455, 530], '1C;': [169], 'S1D).': [171], 'induced': [173], 'higher': [174, 191, 548], 'IL-1β': [175], 'IL-6': [177, 422], 'secretion': [178], 'bone': [180], 'marrow-derived': [181], 'dendritic': [182, 390], 'cells': [183, 208, 287, 373, 391, 411], 'β-1,3/1,6-glucan,': [185], 'suggesting': [186], 'have': [190], 'effect': [193, 313], 'S2A).': [195], 'vitro': [197], 'allergen': [198, 449], 'stimulation': [199], 'assay': [200], 'showed': [201, 269], 'mesenteric': [204], 'lymph': [205], 'node': [206], '(MLN)': [207], 'splenocytes': [210], 'group': [213, 228, 299, 337, 350], 'production': [215, 230, 245, 423], 'Th2': [217], 'cytokine': [218, 222, 233, 335], 'IL-4': [219, 328], 'Th17': [221], 'IL-17A,': [223], 'whereas': [224], 'those': [225], 'Th1': [232], 'IFN-γ': [234], 'MLNs': [236, 427], '1D;': [238], 'S2B).': [240, 263], 'The': [241, 325, 500, 698, 749, 771], 'IL-10': [244], 'frequency': [248, 406], 'Treg': [250], 'tissues': [253, 364], 'were': [254, 342, 490], 'comparable': [255, 491], 'between': [256], 'control': [260], 'groups': [261, 495], 'Histological': [264], 'analysis': [265, 721], 'jejunum': [268], 'β-1,3': [271], 'glucan': [272, 541], 'thickens': [274], 'muscular': [276], 'layer': [277], '1E;': [279], 'S2C).': [281], 'Furthermore,': [282], 'numbers': [284], 'mast': [286, 308, 372], 'eosinophils': [289], 'submucosa': [292], 'allergen-sensitised': [295], 'challenged': [297], '2A;': [301], 'Figures': [302], 'S2D': [303], 'S3A).': [305], 'Ketotifen,': [306], 'cell': [309], 'stabilizer,': [310], 'abolished': [311], 'on': [317, 706], '2B).': [324], 'concentrations': [326], 'IL-5,': [330], 'IL-33,': [333], 'activating': [336], '2': [338, 360], 'innate': [339], 'lymphoid': [340], 'cells,': [341], 'highest': [344], 'intestinal': [346, 371], 'homogenates': [347], '2C).': [352], 'These': [353], 'results': [354, 501], 'suggest': [355, 502], 'promotes': [358, 394], 'type': [359], 'immunity': [361], 'because': [365], 'its': [367], 'increases': [370], 'eosinophils,': [375], 'thereby': [377], 'exacerbates': [378], 'features.': [383, 518], 'IL-6,': [384], 'which': [385, 546], 'is': [386, 510, 533, 547, 745, 773], 'mainly': [387], 'derived': [388], 'macrophages,': [393], 'IgA': [395, 441, 644], 'class-switching': [396], 'B-cells.4': [398], 'We': [399], 'observed': [400], 'CD11c+,': [408], 'or': [409, 779], 'F4/80+': [410], 'expressing': [412], 'TLR2,': [413], 'receptor': [415], 'β-glucans,': [417], 'spleens': [429], 'S3B).': [431], 'Such': [432], 'effects': [433, 598], 'contribute': [437], 'production.': [442], 'diets,': [446], 'sensitization,': [450], 'altered': [451, 506], 'gut': [452, 600, 626], 'microbiome': [453, 505, 601, 627], '(Figures': [456], 'S3C,': [457], 'S4A,B).': [459], 'Lachnospirales,': [463], 'Lachnospiraceae,': [464], '[Eubacterium]': [466], 'ventriosum,': [467], 'producers': [468], 'short': [471], 'chain': [472], 'fatty': [473], 'acids': [474], '(SCFA)': [475], '2D).5': [477], 'majority': [483], 'SCFA,': [485], 'acetate,': [486], 'propionate': [487], 'butylate,': [489], 'among': [492], 'tested': [494], '2E;': [497], 'S4C).': [499], 'by': [507, 724, 786], 'directly': [512], 'related': [513], 'formula': [521], 'for': [522, 704, 712, 719, 776, 802], 'human': [523, 543], 'equivalent': [524, 534], 'dose,': [525], '5%': [526], '(25': [531], 'g)': [532], 'approximately': [536], '32': [537], 'g/day': [538, 558], '(60': [544], 'kg),': [545], 'average': [551], 'intake': [553, 574], '16': [555], '29': [557], 'adults.6': [560], 'Collectively,': [561], 'our': [562], 'study': [563, 757], 'indicates': [564], 'features': [568], 'might': [569], 'be': [570, 604, 796], 'more': [571], 'severe': [572], 'upon': [573, 764], 'high': [576], 'doses': [577], 'potential': [582], 'adjuvants': [589], 'IgA-boosting': [591], 'effects.': [592], 'Association': [593], 'β-glucans': [595], 'investigated': [605], 'furthermore.': [606], 'Chaoqi': [607, 618, 665, 678], 'He': [608, 679], 'Yunhui': [610], 'Liu': [611], 'performed': [612, 625, 658], 'animal': [613, 715], 'experiments': [614], 'immune': [616], 'assays.': [617], 'He,': [619, 666], 'Shunsuke': [620], 'Nishio,': [621], 'Tsukasa': [623, 674], 'Matsuda': [624, 675], 'analysis.': [628, 633], 'Ting-Yu': [629], 'Cheng': [630], 'supported': [631, 643, 723], 'FACS': [632], 'Yingnan': [634], 'Guo': [635], 'verified': [636], 'data': [637, 750], 'diet.': [640], 'Tomonori': [641], 'Nochi': [642], 'measurement': [645, 708], 'interpretation': [647], 'histology': [649], 'data.': [650, 677], 'Hannah': [651], 'Rainer,': [652], 'Krause': [653], 'Maren,': [654], 'Stefan': [656, 667, 669], 'Schülke': [657], 'BMDC': [659], 'experiments.': [660, 716], 'Together': [661], 'Masako': [663, 681, 686], 'Toda,': [664], 'Vieths,': [668], 'Schülke,': [670], 'Stephan': [671], 'Scheurer,': [672], 'interpretated': [676], 'Toda': [682, 687], 'wrote': [683], 'paper.': [685], 'designed': [688], 'supervised': [690], 'study.': [692], 'All': [693], 'authors': [694, 699], 'reviewed': [695], 'manuscript.': [697], 'thanks': [700], 'Professor': [701], 'Ikeda': [702], 'Ikuo': [703], 'advice': [705], 'SCFA': [707], 'Kota': [710], 'Torii': [711], 'support': [713, 752], 'Sample': [717], 'preparation': [718], 'histological': [720], 'was': [722], 'Biomedical': [725], 'Research': [726], 'Core': [727], 'Tohoku': [729], 'University': [730], 'Graduate': [731], 'School': [732], 'Medicine.': [734], 'Funding': [735], 'sources': [736], 'indicated': [738], 'supplemental': [740, 747], 'file.': [741, 748], 'Statement': [742], 'COI': [744], 'findings': [754], 'this': [756], 'available': [759], 'corresponding': [762, 800], 'author': [763, 801], 'reasonable': [765], 'request.': [766], 'Data': [767], 'S1.': [768], 'Please': [769], 'note:': [770], 'publisher': [772], 'responsible': [775], 'content': [778], 'functionality': [780], 'any': [782], 'supporting': [783], 'information': [784], 'supplied': [785], 'authors.': [788], 'Any': [789], 'queries': [790], '(other': [791], 'missing': [793], 'content)': [794], 'should': [795], 'directed': [797], 'article.': [804]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4385751324', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}], 'updated_date': '2024-12-24T03:23:45.113014', 'created_date': '2023-08-12'}