Title: A STUDY TO EVALUATE THE PREDICTORS OF DIABETIC PERIPHERAL NEUROPATHY AND UTILITY OF MICHIGHAN NEUROPATHY SCREENING INSTRUMENT AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS
Abstract:Background and Objective: Diabetic neuropathy signicantly lowers the quality of life. The objective of study is to assess the predictors of peripheral neuropathy in patients with type 2 Diabetes Mell...Background and Objective: Diabetic neuropathy signicantly lowers the quality of life. The objective of study is to assess the predictors of peripheral neuropathy in patients with type 2 Diabetes Mellitus attending diabetes clinic and to evaluate the sensitivity and specicity of Michigan Neuropathy Screening Instrument considering neurothesiometer as standard. Methods: In 110 type 2 diabetic patents attending diabetic clinic in Bangalore Medical and Research institute , a cross sectional study conducted where they are screened for diabetic peripheral neuropathy using Michighan Neuropathy Screening Instrument and compared with Neurothesiometer as standard which is further compared to patient's duration of diabetes, treatment modality and glycemic control. Results: Overall the prevalence of diabetic peripheral neuropathy in this study was 51.8 % using the neurothesiometer as standard, large bre neuropathy in 43.8 %, small bre neuropathy in 24.5% and both in 31.5%. Of total 51.8% patients with neuropathy 59.6 % have mild neuropathy, 19.2% have moderate and 21.2 % have severe neuropathy. The Michigan Neuropathy Screening Instrument (MNSI) is found to have Sensitivity of 91%, Specicity of 60%, PPV of 71%, NPV of 86% and Accuracy 76% Conclusion: The study shows that a signicant association is found between age of patient, duration of diabetes, glycemic control (HbA1c), BMI and Diabetic peripheral neuropathy. With accuracy of Michigan Neuropathy Screening Instrument 76 % is helpful to detect peripheral neuropathy in initial stages in clinical settings, in a simple and cost effective mannerRead More
Publication Year: 2023
Publication Date: 2023-07-01
Language: en
Type: article
Indexed In: ['crossref']
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