Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4381989239', 'doi': 'https://doi.org/10.1016/j.intimp.2023.110556', 'title': 'Besides TLR2 and TLR4, NLRP3 is also involved in regulating Escherichia coli infection-induced inflammatory responses in mice', 'display_name': 'Besides TLR2 and TLR4, NLRP3 is also involved in regulating Escherichia coli infection-induced inflammatory responses in mice', 'publication_year': 2023, 'publication_date': '2023-06-25', 'ids': {'openalex': 'https://openalex.org/W4381989239', 'doi': 'https://doi.org/10.1016/j.intimp.2023.110556', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37364329'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.intimp.2023.110556', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S158377717', 'display_name': 'International Immunopharmacology', 'issn_l': '1567-5769', 'issn': ['1567-5769', '1878-1705'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.researchsquare.com/article/rs-2594406/latest.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5106471623', 'display_name': 'Yuan Shen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}, {'id': 'https://openalex.org/I44673925', 'display_name': 'Inner Mongolia Medical University', 'ror': 'https://ror.org/01mtxmr84', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I44673925']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuan Shen', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Key Laboratory of Molecular Epidemiology of Chronic Diseases, School of Public Health, Inner Mongolia Medical University, No. 5, Xinhua Street, Hui Min District, 010000, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Key Laboratory of Molecular Epidemiology of Chronic Diseases, School of Public Health, Inner Mongolia Medical University, No. 5, Xinhua Street, Hui Min District, 010000, Hohhot City, China', 'institution_ids': ['https://openalex.org/I44673925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037309850', 'display_name': 'Zhiguo Gong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhiguo Gong', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102339497', 'display_name': 'Shuangyi Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shuangyi Zhang', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020199147', 'display_name': 'Jinshan Cao', 'orcid': 'https://orcid.org/0000-0002-3644-5082'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jinshan Cao', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100392071', 'display_name': 'W. F. Mader', 'orcid': 'https://orcid.org/0000-0002-7344-998X'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei Mao', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5106886675', 'display_name': 'Yuan Yao', 'orcid': 'https://orcid.org/0000-0002-9303-5856'}, 'institutions': [{'id': 'https://openalex.org/I4210124900', 'display_name': "Inner Mongolia People's Hospital", 'ror': 'https://ror.org/02yng3249', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124900']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuan Yao', 'raw_affiliation_strings': ["Department of Neurology, Inner Mongolia People's Hospital, No. 20, Zhaowuda Road, Saihan District, 010017, Hohhot City, China"], 'affiliations': [{'raw_affiliation_string': "Department of Neurology, Inner Mongolia People's Hospital, No. 20, Zhaowuda Road, Saihan District, 010017, Hohhot City, China", 'institution_ids': ['https://openalex.org/I4210124900']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103238769', 'display_name': 'Jiamin Zhao', 'orcid': 'https://orcid.org/0009-0003-8719-2702'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiamin Zhao', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063620011', 'display_name': 'Qianru Li', 'orcid': 'https://orcid.org/0000-0003-3356-5756'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qianru Li', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100398799', 'display_name': 'Kun Liu', 'orcid': 'https://orcid.org/0000-0003-1366-4546'}, 'institutions': [{'id': 'https://openalex.org/I44673925', 'display_name': 'Inner Mongolia Medical University', 'ror': 'https://ror.org/01mtxmr84', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I44673925']}, {'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kun Liu', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Key Laboratory of Molecular Epidemiology of Chronic Diseases, School of Public Health, Inner Mongolia Medical University, No. 5, Xinhua Street, Hui Min District, 010000, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Molecular Epidemiology of Chronic Diseases, School of Public Health, Inner Mongolia Medical University, No. 5, Xinhua Street, Hui Min District, 010000, Hohhot City, China', 'institution_ids': ['https://openalex.org/I44673925']}, {'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072883829', 'display_name': 'Bo Liu', 'orcid': 'https://orcid.org/0000-0002-1961-960X'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Bo Liu', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045108571', 'display_name': 'Shuang Feng', 'orcid': 'https://orcid.org/0000-0003-4739-2518'}, 'institutions': [{'id': 'https://openalex.org/I120379545', 'display_name': 'Inner Mongolia Agricultural University', 'ror': 'https://ror.org/015d0jq83', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I120379545']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Shuang Feng', 'raw_affiliation_strings': ['Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'Laboratory of Veterinary Public Health, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, Ministry of Agriculture, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}, {'raw_affiliation_string': 'Laboratory of Veterinary Public Health, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 29, Erdosdong Road, Saihan District, 010011, Hohhot City, China', 'institution_ids': ['https://openalex.org/I120379545']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5072883829', 'https://openalex.org/A5045108571'], 'corresponding_institution_ids': ['https://openalex.org/I120379545', 'https://openalex.org/I120379545'], 'apc_list': {'value': 3130, 'currency': 'USD', 'value_usd': 3130, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.822, 'has_fulltext': False, 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.99998, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '121', 'issue': None, 'first_page': '110556', 'last_page': '110556'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11313', 'display_name': 'Immune cells in cancer', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pyrin-domain', 'display_name': 'Pyrin domain', 'score': 0.7553433}, {'id': 'https://openalex.org/keywords/escherichia-coli-infection', 'display_name': 'Escherichia coli infection', 'score': 0.71328455}], 'concepts': [{'id': 'https://openalex.org/C2781236682', 'wikidata': 'https://www.wikidata.org/wiki/Q410015', 'display_name': 'TLR2', 'level': 4, 'score': 0.92339826}, {'id': 'https://openalex.org/C2776070231', 'wikidata': 'https://www.wikidata.org/wiki/Q14914098', 'display_name': 'TLR4', 'level': 3, 'score': 0.87029445}, {'id': 'https://openalex.org/C139174496', 'wikidata': 'https://www.wikidata.org/wiki/Q24725912', 'display_name': 'Pyrin domain', 'level': 4, 'score': 0.7553433}, {'id': 'https://openalex.org/C2777209026', 'wikidata': 'https://www.wikidata.org/wiki/Q412405', 'display_name': 'Inflammasome', 'level': 3, 'score': 0.71655804}, {'id': 'https://openalex.org/C2909437661', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli infection', 'level': 4, 'score': 0.71328455}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.7005146}, {'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.69816047}, {'id': 'https://openalex.org/C2776709828', 'wikidata': 'https://www.wikidata.org/wiki/Q408004', 'display_name': 'Toll-like receptor', 'level': 4, 'score': 0.69129854}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.6707734}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53210866}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.49773005}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.44953683}, {'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.43337458}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4282213}, {'id': 'https://openalex.org/C2776460866', 'wikidata': 'https://www.wikidata.org/wiki/Q170065', 'display_name': 'Pathogen', 'level': 2, 'score': 0.42316145}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.3776243}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.20176005}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.07477233}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.07133868}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.06618407}], 'mesh': [{'descriptor_ui': 'D004927', 'descriptor_name': 'Escherichia coli Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051195', 'descriptor_name': 'Toll-Like Receptor 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071199', 'descriptor_name': 'NLR Family, Pyrin Domain-Containing 3 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051197', 'descriptor_name': 'Toll-Like Receptor 4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.intimp.2023.110556', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S158377717', 'display_name': 'International Immunopharmacology', 'issn_l': '1567-5769', 'issn': ['1567-5769', '1878-1705'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.21203/rs.3.rs-2594406/v1', 'pdf_url': 'https://www.researchsquare.com/article/rs-2594406/latest.pdf', 'source': {'id': 'https://openalex.org/S4306402450', 'display_name': 'Research Square (Research Square)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4210096694', 'host_organization_name': 'Research Square (United States)', 'host_organization_lineage': ['https://openalex.org/I4210096694'], 'host_organization_lineage_names': ['Research Square (United States)'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37364329', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.21203/rs.3.rs-2594406/v1', 'pdf_url': 'https://www.researchsquare.com/article/rs-2594406/latest.pdf', 'source': {'id': 'https://openalex.org/S4306402450', 'display_name': 'Research Square (Research Square)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4210096694', 'host_organization_name': 'Research Square (United States)', 'host_organization_lineage': ['https://openalex.org/I4210096694'], 'host_organization_lineage_names': ['Research Square (United States)'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.67, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 63, 'referenced_works': ['https://openalex.org/W1605279589', 'https://openalex.org/W1747736870', 'https://openalex.org/W1926510675', 'https://openalex.org/W1966836820', 'https://openalex.org/W1972483153', 'https://openalex.org/W1975032025', 'https://openalex.org/W1976644844', 'https://openalex.org/W1978330299', 'https://openalex.org/W1979413396', 'https://openalex.org/W1981833837', 'https://openalex.org/W1987002258', 'https://openalex.org/W1987381421', 'https://openalex.org/W1987535382', 'https://openalex.org/W1990908543', 'https://openalex.org/W1995586746', 'https://openalex.org/W1995744610', 'https://openalex.org/W2004465286', 'https://openalex.org/W2009800174', 'https://openalex.org/W2015833994', 'https://openalex.org/W2036767516', 'https://openalex.org/W2043788424', 'https://openalex.org/W2043799666', 'https://openalex.org/W2043823247', 'https://openalex.org/W2046783872', 'https://openalex.org/W2052798287', 'https://openalex.org/W2057809738', 'https://openalex.org/W2067740038', 'https://openalex.org/W2072890032', 'https://openalex.org/W2083119828', 'https://openalex.org/W2084777655', 'https://openalex.org/W2087928405', 'https://openalex.org/W2090859543', 'https://openalex.org/W2094830630', 'https://openalex.org/W2095083007', 'https://openalex.org/W2107277218', 'https://openalex.org/W2109491705', 'https://openalex.org/W2113653640', 'https://openalex.org/W2118403357', 'https://openalex.org/W2124145819', 'https://openalex.org/W2126384811', 'https://openalex.org/W2127453904', 'https://openalex.org/W2138738692', 'https://openalex.org/W2143119237', 'https://openalex.org/W2162969545', 'https://openalex.org/W2462668740', 'https://openalex.org/W2528948463', 'https://openalex.org/W2533938426', 'https://openalex.org/W2545368922', 'https://openalex.org/W2800680658', 'https://openalex.org/W2888455562', 'https://openalex.org/W2904872097', 'https://openalex.org/W2947089396', 'https://openalex.org/W2947570164', 'https://openalex.org/W2967095202', 'https://openalex.org/W3007007659', 'https://openalex.org/W3206075574', 'https://openalex.org/W4205471480', 'https://openalex.org/W4221050210', 'https://openalex.org/W4226092998', 'https://openalex.org/W4302363667', 'https://openalex.org/W4306246974', 'https://openalex.org/W4307553671', 'https://openalex.org/W4324129408'], 'related_works': ['https://openalex.org/W4381989239', 'https://openalex.org/W4321163868', 'https://openalex.org/W3170880456', 'https://openalex.org/W3158332146', 'https://openalex.org/W2905572223', 'https://openalex.org/W2800130866', 'https://openalex.org/W2781757947', 'https://openalex.org/W2558550413', 'https://openalex.org/W2168428983', 'https://openalex.org/W2008631375'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4381989239', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}], 'updated_date': '2024-12-24T03:36:40.358863', 'created_date': '2023-06-26'}