Title: High‐sensitivity C‐reactive protein and bilirubin as possible biomarkers for hikikomori in depression: A case‐control study
Abstract: Psychiatry and Clinical NeurosciencesAccepted Articles Letter to the Editor High-sensitivity C-reactive protein and bilirubin as possible biomarkers for hikikomori in depression: a case–control study Sota Kyuragi MD, Sota Kyuragi MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorToshio Matsushima MD, Toshio Matsushima MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorMatsuo Keitaro MD, Matsuo Keitaro MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorTomohiro Nakao MD, PhD, Tomohiro Nakao MD, PhD orcid.org/0000-0002-4420-6903 Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorTakahiro A Kato MD, PhD, Corresponding Author Takahiro A Kato MD, PhD [email protected] orcid.org/0000-0001-5169-2930 Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Correspondence: Takahiro A. Kato, MD, PhD (Associate Professor, Kyushu University), Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, Fukuoka, Japan 812-8582, Tel: +81-92-642-5627; Fax: +81-92-642-5644, Email: [email protected]Search for more papers by this author Sota Kyuragi MD, Sota Kyuragi MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorToshio Matsushima MD, Toshio Matsushima MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorMatsuo Keitaro MD, Matsuo Keitaro MD Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorTomohiro Nakao MD, PhD, Tomohiro Nakao MD, PhD orcid.org/0000-0002-4420-6903 Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanSearch for more papers by this authorTakahiro A Kato MD, PhD, Corresponding Author Takahiro A Kato MD, PhD [email protected] orcid.org/0000-0001-5169-2930 Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Correspondence: Takahiro A. Kato, MD, PhD (Associate Professor, Kyushu University), Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, Fukuoka, Japan 812-8582, Tel: +81-92-642-5627; Fax: +81-92-642-5644, Email: [email protected]Search for more papers by this author First published: 11 May 2023 https://doi.org/10.1111/pcn.13564 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/pcn.13564. AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Supporting Information Filename Description pcn13564-sup-0001-Supinfo.docxWord 2007 document , 22.6 KB Data S1 Supporting Information pcn13564-sup-0002-TableS1.docxWord 2007 document , 33.7 KB Table S1 The comparison of demographic and clinical characteristics in MDD with and without hikikomori. Statistically significant results are shown in bold; * = p < 0.05, ** = p < 0.01, *** = p < 0.0001 Effect sizes are r for independent Welch's t-test†or Mann–Whitney U test‡ and Cramer's V for chi-square test§. Unit is “mg/dL” for HDL.C, LDL.C, FIB, bilirubin, UA, hsCRP and “μg/mL” for FDP. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Accepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset version of record will appear in the future. RelatedInformation