Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4367304111', 'doi': 'https://doi.org/10.1212/wnl.0000000000203492', 'title': 'Neurofilament Light Chain Levels and Disease Activity During Long-Term Treatment of Relapsing Multiple Sclerosis with the Bruton’s Tyrosine Kinase Inhibitor Evobrutinib (P1-3.011)', 'display_name': 'Neurofilament Light Chain Levels and Disease Activity During Long-Term Treatment of Relapsing Multiple Sclerosis with the Bruton’s Tyrosine Kinase Inhibitor Evobrutinib (P1-3.011)', 'publication_year': 2023, 'publication_date': '2023-04-25', 'ids': {'openalex': 'https://openalex.org/W4367304111', 'doi': 'https://doi.org/10.1212/wnl.0000000000203492'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.0000000000203492', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045590592', 'display_name': 'Jens Kühle', 'orcid': 'https://orcid.org/0000-0002-6963-8892'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jens Kuhle', 'raw_affiliation_strings': ['Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, and University of Basel'], 'affiliations': [{'raw_affiliation_string': 'Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, and University of Basel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063009739', 'display_name': 'Ludwig Kappos', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802542264', 'display_name': 'University Hospital of Basel', 'ror': 'https://ror.org/04k51q396', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802542264']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Ludwig Kappos', 'raw_affiliation_strings': ['Departments of Medicine, Clinical Research and Biomedical Engineering, Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, and University of Basel'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine, Clinical Research and Biomedical Engineering, Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, and University of Basel', 'institution_ids': ['https://openalex.org/I2802542264', 'https://openalex.org/I1850255']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031171090', 'display_name': 'Xavier Montalbán', 'orcid': 'https://orcid.org/0000-0002-0098-9918'}, 'institutions': [{'id': 'https://openalex.org/I4396570551', 'display_name': "Centre d'Esclerosi Múltiple de Catalunya", 'ror': 'https://ror.org/01kzbqm05', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4396570551']}], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xavier Montalban', 'raw_affiliation_strings': ['Department of Neurology-Neuroimmunology, Centre d’Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitario Vall d’Hebron'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology-Neuroimmunology, Centre d’Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitario Vall d’Hebron', 'institution_ids': ['https://openalex.org/I4396570551']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080501336', 'display_name': 'Pascal Benkert', 'orcid': 'https://orcid.org/0000-0001-6525-8174'}, 'institutions': [{'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Pascal Benkert', 'raw_affiliation_strings': ['Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel'], 'affiliations': [{'raw_affiliation_string': 'Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel', 'institution_ids': ['https://openalex.org/I1850255']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100413989', 'display_name': 'Ying Li', 'orcid': 'https://orcid.org/0000-0001-5062-0230'}, 'institutions': [{'id': 'https://openalex.org/I862255436', 'display_name': 'Merck Serono (Italy)', 'ror': 'https://ror.org/01z6wpz16', 'country_code': 'IT', 'type': 'company', 'lineage': ['https://openalex.org/I164928964', 'https://openalex.org/I862255436']}, {'id': 'https://openalex.org/I164928964', 'display_name': 'Merck (Germany)', 'ror': 'https://ror.org/04b2dty93', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I164928964']}], 'countries': ['DE', 'IT'], 'is_corresponding': False, 'raw_author_name': 'Ying Li', 'raw_affiliation_strings': ['EMD Serono'], 'affiliations': [{'raw_affiliation_string': 'EMD Serono', 'institution_ids': ['https://openalex.org/I862255436', 'https://openalex.org/I164928964']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5104209963', 'display_name': 'Karthinathan Thangavelu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I862255436', 'display_name': 'Merck Serono (Italy)', 'ror': 'https://ror.org/01z6wpz16', 'country_code': 'IT', 'type': 'company', 'lineage': ['https://openalex.org/I164928964', 'https://openalex.org/I862255436']}, {'id': 'https://openalex.org/I164928964', 'display_name': 'Merck (Germany)', 'ror': 'https://ror.org/04b2dty93', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I164928964']}], 'countries': ['DE', 'IT'], 'is_corresponding': False, 'raw_author_name': 'Karthinathan Thangavelu', 'raw_affiliation_strings': ['EMD Serono'], 'affiliations': [{'raw_affiliation_string': 'EMD Serono', 'institution_ids': ['https://openalex.org/I862255436', 'https://openalex.org/I164928964']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037407336', 'display_name': 'Yann Hyvert', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I164928964', 'display_name': 'Merck (Germany)', 'ror': 'https://ror.org/04b2dty93', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I164928964']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Yann Hyvert', 'raw_affiliation_strings': ['The healthcare business of Merck KGaA, Darmstadt, Germany'], 'affiliations': [{'raw_affiliation_string': 'The healthcare business of Merck KGaA, Darmstadt, Germany', 'institution_ids': ['https://openalex.org/I164928964']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045970247', 'display_name': 'Davorka Tomic', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I164928964', 'display_name': 'Merck (Germany)', 'ror': 'https://ror.org/04b2dty93', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I164928964']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Davorka Tomic', 'raw_affiliation_strings': ['Ares Trading SA, Eysins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany'], 'affiliations': [{'raw_affiliation_string': 'Ares Trading SA, Eysins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany', 'institution_ids': ['https://openalex.org/I164928964']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.626, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.69718, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 67, 'max': 78}, 'biblio': {'volume': '100', 'issue': '17_supplement_2', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11157', 'display_name': 'Chronic Lymphocytic Leukemia Research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11157', 'display_name': 'Chronic Lymphocytic Leukemia Research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11215', 'display_name': 'Chronic Myeloid Leukemia Treatments', 'score': 0.9889, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10755', 'display_name': 'HER2/EGFR in Cancer Research', 'score': 0.9779, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.684249}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6424675}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.58270764}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.46635595}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.4407732}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.44055858}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.13610256}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.0000000000203492', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.78, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2533581028', 'https://openalex.org/W2391409986', 'https://openalex.org/W2159000141', 'https://openalex.org/W2037631372', 'https://openalex.org/W2030889776', 'https://openalex.org/W1979139803', 'https://openalex.org/W1978297557', 'https://openalex.org/W1974041167', 'https://openalex.org/W1966775726', 'https://openalex.org/W1966504330'], 'abstract_inverted_index': {'<h3>Objective:</h3>': [0], 'To': [1], 'evaluate': [2], 'neurofilament': [3], 'light': [4], 'chain': [5], '(NfL)': [6], 'levels,': [7], 'a': [8, 14, 17, 39, 68, 138, 267, 290, 297, 577, 602, 623, 646, 667, 688, 710, 732, 754, 773, 798, 822, 847, 873, 897, 922, 949, 977, 1005], 'biomarker': [9], 'of': [10, 21, 55, 67, 92, 128, 144, 149, 212, 287, 293, 314, 325, 336, 347, 358, 369, 381, 392, 403, 414, 425, 436, 459, 470, 482, 495, 507, 520, 532, 546, 559, 587, 597, 608, 618, 631, 641, 652, 662, 673, 683, 695, 705, 717, 727, 739, 749, 768, 793, 817, 842, 868, 892, 917, 934, 944, 962, 972, 990, 1000, 1017, 1028, 1040, 1052, 1065, 1076, 1088, 1100, 1127, 1141, 1155, 1170, 1174, 1183, 1195, 1199], 'neuroaxonal': [11], 'damage,': [12], 'as': [13, 123, 289, 601, 622, 645, 666, 687, 709, 731, 753, 1124, 1138, 1152, 1167, 1192], 'prognostic': [15, 291], 'and': [16, 26, 58, 121, 152, 158, 160, 187, 189, 226, 242, 281, 296], 'potential': [18, 298], 'surrogate': [19, 299], 'marker': [20, 292, 300], 'evobrutinib': [22, 56, 104], 'treatment': [23, 303], 'response': [24], '(MRI': [25, 57], 'relapse': [27, 228, 282], 'outcomes)': [28, 60], 'in': [29, 48, 62, 73, 77, 100, 115, 137, 253, 266, 594, 615, 638, 659, 680, 702, 724, 746, 765, 790, 814, 839, 865, 889, 914, 941, 969, 997], 'patients': [30, 213, 254], 'with': [31, 103, 214, 278], 'relapsing': [32], 'multiple': [33], 'sclerosis': [34], '(PwRMS).': [35], '<h3>Background:</h3>': [36], 'Evobrutinib': [37, 262], 'is': [38], 'highly': [40], 'selective,': [41], 'CNS-penetrant': [42], "Bruton's": [43], 'tyrosine': [44], 'kinase': [45], 'inhibitor,': [46], 'currently': [47], 'Phase': [49, 69, 94], 'III': [50], 'for': [51, 301, 599, 604, 620, 625, 643, 648, 664, 669, 685, 690, 707, 712, 729, 734, 751, 756, 770, 781, 795, 806, 819, 830, 844, 855, 870, 881, 894, 905, 919, 930, 946, 957, 974, 985, 1002, 1013, 1122, 1136, 1150, 1165, 1190], 'RMS.': [52], 'The': [53, 147, 312, 323, 334, 345, 356, 367, 379, 390, 401, 412, 423, 434, 457, 468, 480, 493, 505, 518, 530, 544, 557, 585, 606, 629, 650, 671, 693, 715, 737, 932, 960, 988, 1015, 1026, 1038, 1050, 1063, 1074, 1086, 1098, 1171, 1196], 'efficacy': [54], 'clinical': [59], 'observed': [61, 252], 'double': [63], 'blind': [64], 'phase': [65], '(DBP)': [66], 'II': [70, 95], 'trial': [71, 96], '(NCT02975349)': [72], 'PwRMS': [74], 'was': [75], 'maintained': [76], 'the': [78, 93, 116, 180, 210, 285, 595, 616, 639, 660, 681, 703, 725, 747, 766, 791, 815, 840, 866, 890, 915, 942, 970, 998], 'open-label': [79], 'extension': [80], '(OLE;': [81], 'beginning': [82], 'at': [83, 156, 185, 224], 'Week': [84], '[W]': [85], '48': [86], 'from': [87, 133, 321, 332, 343, 354, 365, 376, 388, 399, 410, 421, 432, 443, 466, 477, 489, 502, 514, 527, 539, 553, 566, 576, 1024, 1035, 1047, 1059, 1072, 1083, 1095, 1107], 'DBP': [88], 'baseline).': [89], 'Previous': [90], 'analyses': [91], 'showed': [97], 'sustained': [98, 268], 'reductions': [99], 'NfL': [101, 109, 125, 135, 170, 199, 264, 274, 288], 'levels': [102, 110, 265, 275], 'up': [105], 'to': [106, 271, 310, 582, 1114, 1208], 'W144.': [107], '<h3>Design/Methods:</h3>': [108], 'were': [111, 165, 193, 231, 251, 276], 'measured': [112], 'over': [113, 163, 191], 'time': [114], 'pooled': [117], 'OLE': [118], 'safety': [119], 'population': [120, 140], 'reported': [122], 'control-adjusted': [124], 'Z-scores': [126, 171, 200, 207, 258], '(expression': [127], 'standard': [129], 'deviations': [130], '[SDs]': [131], 'away': [132], 'mean': [134], 'level': [136], 'control': [139, 181], '[participants': [141], 'without': [142], 'evidence': [143], 'CNS': [145], 'disease]).': [146], 'number': [148], 'T1': [150, 216], 'Gd+': [151, 217], 'new/emerging': [153], 'T2': [154, 221], 'lesions': [155, 222], 'W96': [157, 169, 188, 206], 'W144': [159], 'qualified': [161], 'relapses': [162, 190], 'W96–144': [164, 230], 'assessed,': [166], 'stratified': [167, 197, 255], 'by': [168, 205, 256], '(<1;': [172], '≥1': [173], '[Z-score': [174], '1': [175], 'being': [176], 'one': [177], 'SD': [178], 'above': [179], 'mean]).': [182], 'MRI': [183, 280], 'outcomes': [184], 'W48': [186, 198, 257], 'W48–96': [192], 'also': [194], 'assessed': [195], 'using': [196], '[<1;': [201], '≥1].': [202], '<h3>Results:</h3>': [203], 'Stratified': [204], '(<1[N=66];': [208], '≥1[N=34]),': [209], 'proportion': [211], 'no': [215, 219, 227], 'lesions,': [218], 'new/enlarging': [220], '(both': [223], 'W144)': [225], 'between': [229], '84.5%': [232], '(n=49/58)': [233], 'vs': [234, 239, 245], '57.1%': [235], '(n=16/28),': [236], '65.5%': [237], '(n=38/58)': [238], '28.6%': [240], '(n=8/28)': [241], '95.4%': [243], '(n=62/65)': [244], '94.1%': [246], '(n=32/34),': [247], 'respectively.': [248], 'Similar': [249], 'findings': [250], '(<1[N=84];': [259], '≥1[N=40]).': [260], '<h3>Conclusions:</h3>': [261], 'reduced': [263], 'manner': [269], '(up': [270], 'W144).': [272], 'Low': [273], 'associated': [277], 'improved': [279], 'outcomes,': [283], 'supporting': [284], 'role': [286], 'disease': [294], 'activity': [295], "evobrutinib's": [302], 'effect.': [304], '<b>Disclosure:</b>': [305], 'Dr.': [306, 315, 326, 337, 348, 359, 370, 382, 393, 404, 415, 426, 437, 460, 471, 483, 496, 508, 521, 533, 547, 560, 569, 588, 609, 632, 653, 674, 696, 718, 740, 759, 784, 808, 833, 859, 883, 908, 935, 963, 991, 1018, 1029, 1041, 1053, 1066, 1077, 1089, 1101, 1159, 1184], 'Kuhle': [307], 'has': [308, 317, 328, 339, 350, 361, 372, 384, 395, 406, 417, 428, 439, 462, 473, 485, 498, 510, 523, 535, 549, 562, 571, 590, 611, 634, 655, 676, 698, 720, 742, 761, 786, 810, 835, 861, 885, 910, 937, 965, 993, 1020, 1031, 1043, 1055, 1068, 1079, 1091, 1103, 1112, 1118, 1132, 1146, 1161, 1186, 1206], 'nothing': [309, 1113, 1207], 'disclose.': [311, 1115, 1209], 'institution': [313, 324, 335, 346, 357, 368, 380, 391, 402, 413, 424, 435, 458, 469, 481, 494, 506, 519, 531, 545, 558, 586, 607, 630, 651, 672, 694, 716, 738, 933, 961, 989, 1016, 1027, 1039, 1051, 1064, 1075, 1087, 1099], 'Kappos': [316, 327, 338, 349, 360, 371, 383, 394, 405, 416, 427, 438, 461, 472, 484, 497, 509, 522, 534, 548, 561, 570], 'received': [318, 329, 340, 351, 362, 373, 385, 396, 407, 418, 429, 440, 463, 474, 486, 499, 511, 524, 536, 550, 563, 572, 591, 612, 635, 656, 677, 699, 721, 743, 762, 787, 811, 836, 862, 886, 911, 938, 966, 994, 1021, 1032, 1044, 1056, 1069, 1080, 1092, 1104, 1119, 1133, 1147, 1162, 1187], 'research': [319, 330, 341, 352, 363, 374, 386, 397, 408, 419, 430, 441, 464, 475, 487, 500, 512, 525, 537, 551, 564, 1022, 1033, 1045, 1057, 1070, 1081, 1093, 1105], 'support': [320, 331, 342, 353, 364, 375, 387, 398, 409, 420, 431, 442, 465, 476, 488, 501, 513, 526, 538, 552, 565, 1023, 1034, 1046, 1058, 1071, 1082, 1094, 1106], 'Bayer.': [322], 'Biogen.': [333, 605, 807, 1025], 'Genentech.': [344], 'Genzyme.': [355, 758, 1049, 1143], 'Janssen.': [366, 714, 783, 1097], 'Merck': [377, 1175, 1200], 'Serono.': [378, 504, 628, 858, 1062, 1129], 'Minoryx.': [389], 'Novartis.': [400, 649, 882, 1073], 'Roche.': [411, 692, 907, 1037], 'Sanofi.': [422], 'Santhera.': [433], 'Swiss': [444, 447], 'MS': [445], 'Society,': [446], 'National': [448], 'Research': [449, 454], 'Foundation,': [450, 455], 'European': [451], 'Union,': [452], 'Roche': [453], 'Innosuisse.': [456], 'Shionogi.': [467], 'Japan': [478], 'Tobacco.': [479], 'Auriga': [490], 'Vision': [491], 'AG.': [492, 529], 'EMD': [503, 627, 857, 1061, 1128, 1156], 'Glaxo': [515], 'Smith': [516], 'Kline.': [517], 'Wellmera': [528], 'Eli': [540], 'Lilly': [541], '(Suisse)': [542], 'SA.': [543], 'Bristol': [554], 'Myers': [555], 'Squibb.': [556], 'Celltrion': [567], 'Inc.': [568], 'intellectual': [573], 'property': [574], 'interests': [575], 'discovery': [578], 'or': [579, 776, 801, 825, 850, 876, 900, 925, 952, 980, 1008], 'technology': [580], 'relating': [581], 'health': [583], 'care.': [584], 'Montalban': [589, 610, 633, 654, 675, 697, 719, 741, 760, 785, 809, 834, 860, 884, 909, 936, 964, 992, 1019, 1030, 1042, 1054, 1067, 1078, 1090, 1102], 'personal': [592, 613, 636, 657, 678, 700, 722, 744, 763, 788, 812, 837, 863, 887, 912, 939, 967, 995, 1120, 1134, 1148, 1163, 1188], 'compensation': [593, 614, 637, 658, 679, 701, 723, 745, 764, 789, 813, 838, 864, 888, 913, 940, 968, 996, 1121, 1135, 1149, 1164, 1189], 'range': [596, 617, 640, 661, 682, 704, 726, 748, 767, 792, 816, 841, 867, 891, 916, 943, 971, 999], '$10,000-$49,999': [598, 619, 642, 728, 818, 843, 918], 'serving': [600, 621, 644, 665, 686, 708, 730, 752, 771, 796, 820, 845, 871, 895, 920, 947, 975, 1003, 1123, 1137, 1151, 1166, 1191], 'Consultant': [603, 624, 647, 668, 689, 711, 733, 755], 'Merck/': [626, 856, 1060], '$5,000-$9,999': [663, 684, 706, 750, 769, 794], 'Teva.': [670], 'Hoffmann-La': [691, 906, 1036], 'Actelion/': [713, 782, 1096], 'BMS/': [735, 831, 1108], 'Celgene.': [736, 832, 1109], 'Sanofi/': [757, 1048], 'on': [772, 797, 821, 846, 872, 896, 921, 948, 976, 1004], 'Scientific': [774, 799, 823, 848, 874, 898, 923, 950, 978, 1006], 'Advisory': [775, 800, 824, 849, 875, 899, 924, 951, 979, 1007], 'Data': [777, 802, 826, 851, 877, 901, 926, 953, 981, 1009], 'Safety': [778, 803, 827, 852, 878, 902, 927, 954, 982, 1010], 'Monitoring': [779, 804, 828, 853, 879, 903, 928, 955, 983, 1011], 'board': [780, 805, 829, 854, 880, 904, 929, 956, 984, 1012], '$500-$4,999': [869, 893, 945, 973, 1001], 'Sanofi-Genzyme.': [931], 'Immunic': [958], 'Therapeutics.': [959], 'Viatris/': [986], 'Mylan.': [987], 'Sandoz.': [1014], 'Teva': [1084], 'Pharmaceuticals.': [1085], 'Pascal': [1110], 'Benkert': [1111], 'Ying': [1116], 'Li': [1117], 'an': [1125, 1139, 1153, 1168, 1193], 'employee': [1126, 1140, 1154, 1169, 1194], 'Karthinathan': [1130, 1144], 'Thangavelu': [1131, 1145], 'Sanofi': [1142], 'Serono': [1157], '.': [1158], 'Hyvert': [1160, 1185], 'healthcare': [1172, 1197], 'business': [1173, 1198], 'KGaA,': [1176, 1201], 'Darmstadt,': [1177, 1202], 'Germany.': [1178, 1203], 'An': [1179], 'immediate': [1180], 'family': [1181], 'member': [1182], 'Davorka': [1204], 'Tomic': [1205]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4367304111', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}], 'updated_date': '2025-01-13T03:16:38.580027', 'created_date': '2023-04-29'}