Construction and Immunogenicity Evaluation of Recombinant Adenovirus-Expressing Capsid Protein of Foot-and-Mouth Disease Virus Types O and A

Name: Work Video:
Duration: 3 min 30 s
Cancan Wang; Liping Zhang; Ruiming Yu; Peng Zhou; Zhongwang Zhang; Xin Miao; Mingxia Li; Jianliang Lv; Li Pan; Yonglu Wang; Xinsheng Liu
{'id': 'https://openalex.org/W4366390736', 'doi': 'https://doi.org/10.3390/zoonoticdis3020010', 'title': 'Construction and Immunogenicity Evaluation of Recombinant Adenovirus-Expressing Capsid Protein of Foot-and-Mouth Disease Virus Types O and A', 'display_name': 'Construction and Immunogenicity Evaluation of Recombinant Adenovirus-Expressing Capsid Protein of Foot-and-Mouth Disease Virus Types O and A', 'publication_year': 2023, 'publication_date': '2023-04-19', 'ids': {'openalex': 'https://openalex.org/W4366390736', 'doi': 'https://doi.org/10.3390/zoonoticdis3020010'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/zoonoticdis3020010', 'pdf_url': 'https://www.mdpi.com/2813-0227/3/2/10/pdf?version=1681889535', 'source': {'id': 'https://openalex.org/S4386622021', 'display_name': 'Zoonotic Diseases', 'issn_l': '2813-0227', 'issn': ['2813-0227'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'diamond', 'oa_url': 'https://www.mdpi.com/2813-0227/3/2/10/pdf?version=1681889535', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5046157907', 'display_name': 'Cancan Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Cancan Wang', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100426745', 'display_name': 'Liping Zhang', 'orcid': 'https://orcid.org/0000-0002-3524-3964'}, 'institutions': [{'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Liping Zhang', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210138501', 'https://openalex.org/I4210090981']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073688185', 'display_name': 'Ruiming Yu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ruiming Yu', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083165835', 'display_name': 'Peng Zhou', 'orcid': 'https://orcid.org/0000-0001-9863-4201'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Peng Zhou', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084678300', 'display_name': 'Zhongwang Zhang', 'orcid': 'https://orcid.org/0009-0006-4202-8556'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhongwang Zhang', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011427600', 'display_name': 'Xin Miao', 'orcid': 'https://orcid.org/0009-0005-4319-2107'}, 'institutions': [{'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xin Miao', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210138501', 'https://openalex.org/I4210090981']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101595794', 'display_name': 'Mingxia Li', 'orcid': 'https://orcid.org/0000-0002-6941-7344'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Mingxia Li', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100953863', 'display_name': 'Jianliang Lv', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianliang Lv', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101952533', 'display_name': 'Li Pan', 'orcid': 'https://orcid.org/0000-0002-8802-1070'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Pan', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017764501', 'display_name': 'Yonglu Wang', 'orcid': 'https://orcid.org/0000-0002-6418-3913'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yonglu Wang', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101747194', 'display_name': 'Xinsheng Liu', 'orcid': 'https://orcid.org/0000-0003-1960-0252'}, 'institutions': [{'id': 'https://openalex.org/I4210090981', 'display_name': 'Lanzhou Veterinary Research Institute', 'ror': 'https://ror.org/00dg3j745', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}, {'id': 'https://openalex.org/I4210138501', 'display_name': 'Chinese Academy of Agricultural Sciences', 'ror': 'https://ror.org/0313jb750', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210127390', 'https://openalex.org/I4210138501', 'https://openalex.org/I4210151987']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xinsheng Liu', 'raw_affiliation_strings': ['State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou 730046, China', 'institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5101747194'], 'corresponding_institution_ids': ['https://openalex.org/I4210090981', 'https://openalex.org/I4210138501'], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 67}, 'biblio': {'volume': '3', 'issue': '2', 'first_page': '104', 'last_page': '119'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11560', 'display_name': 'Animal Disease Management and Epidemiology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1102', 'display_name': 'Agronomy and Crop Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11560', 'display_name': 'Animal Disease Management and Epidemiology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1102', 'display_name': 'Agronomy and Crop Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12733', 'display_name': 'Vector-Borne Animal Diseases', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/1105', 'display_name': 'Ecology, Evolution, Behavior and Systematics'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bivalent', 'display_name': 'Bivalent (engine)', 'score': 0.44582123}], 'concepts': [{'id': 'https://openalex.org/C202878990', 'wikidata': 'https://www.wikidata.org/wiki/Q830465', 'display_name': 'Capsid', 'level': 3, 'score': 0.88113}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.84959984}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.8250758}, {'id': 'https://openalex.org/C2780868878', 'wikidata': 'https://www.wikidata.org/wiki/Q1660197', 'display_name': 'Immunogenicity', 'level': 3, 'score': 0.79861486}, {'id': 'https://openalex.org/C2776151397', 'wikidata': 'https://www.wikidata.org/wiki/Q1911079', 'display_name': 'Foot-and-mouth disease virus', 'level': 3, 'score': 0.7195328}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6022697}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.6002694}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.56142664}, {'id': 'https://openalex.org/C2776954459', 'wikidata': 'https://www.wikidata.org/wiki/Q193447', 'display_name': 'Adenoviridae', 'level': 4, 'score': 0.48070484}, {'id': 'https://openalex.org/C10389963', 'wikidata': 'https://www.wikidata.org/wiki/Q848328', 'display_name': 'Serotype', 'level': 2, 'score': 0.44888228}, {'id': 'https://openalex.org/C2776620830', 'wikidata': 'https://www.wikidata.org/wiki/Q4919211', 'display_name': 'Bivalent (engine)', 'level': 3, 'score': 0.44582123}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.22004262}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.10460189}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.082138866}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C544153396', 'wikidata': 'https://www.wikidata.org/wiki/Q11426', 'display_name': 'Metal', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/zoonoticdis3020010', 'pdf_url': 'https://www.mdpi.com/2813-0227/3/2/10/pdf?version=1681889535', 'source': {'id': 'https://openalex.org/S4386622021', 'display_name': 'Zoonotic Diseases', 'issn_l': '2813-0227', 'issn': ['2813-0227'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/zoonoticdis3020010', 'pdf_url': 'https://www.mdpi.com/2813-0227/3/2/10/pdf?version=1681889535', 'source': {'id': 'https://openalex.org/S4386622021', 'display_name': 'Zoonotic Diseases', 'issn_l': '2813-0227', 'issn': ['2813-0227'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Industry, innovation and infrastructure', 'id': 'https://metadata.un.org/sdg/9', 'score': 0.61}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W1667103125', 'https://openalex.org/W1972258033', 'https://openalex.org/W1978284786', 'https://openalex.org/W2017525640', 'https://openalex.org/W2030404196', 'https://openalex.org/W2046117249', 'https://openalex.org/W2047678524', 'https://openalex.org/W2049376874', 'https://openalex.org/W2051646218', 'https://openalex.org/W2059752410', 'https://openalex.org/W2072206210', 'https://openalex.org/W2083417223', 'https://openalex.org/W2103738533', 'https://openalex.org/W2103906844', 'https://openalex.org/W2122755078', 'https://openalex.org/W2126022534', 'https://openalex.org/W2136152433', 'https://openalex.org/W2136762990', 'https://openalex.org/W2141386720', 'https://openalex.org/W2161552543', 'https://openalex.org/W2168795142', 'https://openalex.org/W2193084023', 'https://openalex.org/W2412070252', 'https://openalex.org/W2473636172', 'https://openalex.org/W2474674566', 'https://openalex.org/W2564714357', 'https://openalex.org/W2599931513', 'https://openalex.org/W2745338045', 'https://openalex.org/W2896281402', 'https://openalex.org/W2913204308', 'https://openalex.org/W2965578240', 'https://openalex.org/W3027138240', 'https://openalex.org/W3042184523', 'https://openalex.org/W3089032315', 'https://openalex.org/W3193876750'], 'related_works': ['https://openalex.org/W4316495397', 'https://openalex.org/W2968050865', 'https://openalex.org/W2769051567', 'https://openalex.org/W2347733161', 'https://openalex.org/W2169851782', 'https://openalex.org/W2137572138', 'https://openalex.org/W2079290149', 'https://openalex.org/W2076921277', 'https://openalex.org/W2061204975', 'https://openalex.org/W2034511141'], 'abstract_inverted_index': {'The': [0, 80], 'objective': [1], 'of': [2, 19, 92, 121, 136, 154], 'this': [3], 'study': [4], 'was': [5], 'to': [6, 28, 162], 'construct': [7], 'a': [8, 137], 'recombinant': [9, 45, 86, 122, 147], 'adenovirus': [10, 59, 123, 148], 'expressing': [11, 149], 'the': [12, 32, 36, 57, 63, 84, 111, 116, 119, 133, 146, 150], 'foot-and-mouth': [13], 'disease': [14], 'virus': [15], '(FMDV)': [16], 'capsid': [17, 152], 'protein': [18, 153], 'types': [20, 100, 124, 155], 'O': [21, 101, 125, 156], 'and': [22, 49, 54, 62, 65, 94, 102, 110, 126, 157], 'A': [23, 103, 158], 'for': [24, 35, 132], 'future': [25, 134], 'FMDV': [26, 99, 151, 164], 'vaccines': [27], 'be': [29, 160], 'used': [30, 161], 'in': [31, 38, 72, 118, 165], 'livestock': [33], 'industry': [34], 'reduction': [37], 'losses': [39], 'caused': [40], 'by': [41], 'FMD': [42, 139], 'outbreaks.': [43], 'Three': [44], 'adenoviruses,': [46], 'rAdv-P12A3B3C-OZK93,': [47], 'rAdv-P12A3B3C-OA58,': [48], 'rAdv-P12A3C-AF72,': [50], 'were': [51, 69], 'packaged,': [52], 'characterized,': [53], 'amplified': [55], 'using': [56], 'AdMaxTM': [58], 'packaging': [60], 'system,': [61], 'humoral': [64, 93], 'cellular': [66, 95], 'immunity': [67], 'levels': [68, 91], 'further': [70], 'evaluated': [71], 'guinea': [73], 'pigs': [74], 'with': [75, 115], 'monovalent': [76, 106], 'or': [77, 107], 'bivalent': [78, 108], 'forms.': [79], 'results': [81, 143], 'showed': [82], 'that': [83, 145], 'three': [85], 'adenoviruses': [87], 'could': [88, 159], 'elicit': [89], 'high': [90], 'immune': [96, 112], 'responses': [97], 'against': [98], 'when': [104], 'immunizing': [105], 'forms,': [109], 'effect': [113], 'changes': [114], 'change': [117], 'proportion': [120], 'A,': [127], 'laying': [128], 'an': [129], 'important': [130], 'foundation': [131], 'development': [135], 'new': [138], 'live-carrier': [140], 'vaccine.': [141], 'These': [142], 'implied': [144], 'prevent': [163], 'livestock.': [166]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4366390736', 'counts_by_year': [], 'updated_date': '2025-01-08T15:19:03.181396', 'created_date': '2023-04-21'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
