Abstract CT098: A first-in-human phase 1 study of LY3410738, a covalent inhibitor of mutant IDH, in advanced IDH-mutant cholangiocarcinoma and other solid tumors

Name: Work Video:
Duration: 3 min 30 s
Jordi Rodón; Lipika Goyal; T. Macarulla Mercadé; Masafumi Ikeda; Shunsuke Kondo; Do‐Youn Oh; Li‐Yuan Bai; Makoto Ueno; Antoîne Italiano; Kyriakos P. Papadopoulos; David R. Spigel; Sani H. Kizilbash; Rasha Cosman; Joon Oh Park; Li‐Tzong Chen; Tomoya Yokota; Anita Turk; Chih‐Yi Liao; Rachna T. Shroff; Anthony B. El-Khoueiry; Taroh Satoh; Antoine Hollebecque; Mitesh J. Borad; Nilofer S. Azad; Kurt A. Jaeckle; Herbert H. Loong; Jorge Adeva; Wei Peng Yong; Junjie Zhao; Hui Liu; Anna M. Szpurka; Ivelina Gueorguieva; Kamnesh R. Pradhan; Xiaojian Xu; James J. Harding
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'setting,': [347], 'exhibited': [352], 'prolonged': [353], 'stable': [354], 'disease.': [355], 'RP2D': [356], 'evaluation': [357], 'ongoing.': [359], 'Updated': [360], 'data': [361], 'will': [365], 'be': [366], 'presented': [367], 'meeting.': [370], 'Citation': [371], 'Format:': [372], 'Jordi': [373], 'Rodon,': [374], 'Lipika': [375], 'Goyal,': [376], 'Teresa': [377], 'Macarulla': [378], 'Mercade,': [379], 'Masafumi': [380], 'Ikeda,': [381], 'Shunsuke': [382], 'Kondo,': [383], 'Do-Youn': [384], 'Oh,': [385], 'Li-Yuan': [386], 'Bai,': [387], 'Makoto': [388], 'Ueno,': [389], 'Antoine': [390, 419], 'Italiano,': [391], 'Kyriakos': [392], 'Papadopoulos,': [393], 'David': [394], 'Spigel,': [395], 'Sani': [396], 'H.': [397, 430], 'Kizilbash,': [398], 'Rasha': [399], 'Cosman,': [400], 'Joon': [401], 'Oh': [402], 'Park,': [403], 'Li-Tzong': [404], 'Chen,': [405], 'Tomoya': [406], 'Yokota,': [407], 'Anita': [408], 'A.': [409, 427], 'Turk,': [410], 'Chih-Yi': [411], 'Liao,': [412], 'Rachna': [413], 'Shroff,': [414], 'Anthony': [415], 'El-Khoueiry,': [416], 'Taroh': [417], 'Satoh,': [418], 'Hollebecque,': [420], 'Mitesh': [421], 'J.': [422, 452], 'Borad,': [423], 'Nilofer': [424], 'Azad,': [425], 'Kurt': [426], 'Jaeckle,': [428], 'Herbert': [429], 'Loong,': [431], 'Jorge': [432], 'Adeva,': [433], 'Wei': [434], 'Peng': [435], 'Yong,': [436], 'Junjie': [437], 'Zhao,': [438], 'Hui': [439], 'Liu,': [440], 'Anna': [441], 'M.': [442], 'Szpurka,': [443], 'Ivelina': [444], 'Gueorguieva,': [445], 'Kamnesh': [446], 'R.': [447], 'Pradhan,': [448], 'Xiaojian': [449], 'Xu,': [450], 'James': [451], 'Harding.': [453], 'A': [454], 'LY3410738,': [460], 'covalent': [462], 'mutant': [465], 'IDH,': [466], 'IDH-mutant': [469], '[abstract].': [475], 'In:': [476], 'Proceedings': [477], 'American': [480], 'Association': [481], 'Cancer': [483, 503], 'Research': [484], 'Annual': [485], 'Meeting': [486], '2023;': [487], 'Part': [488], '(Clinical': [490], 'Trials': [491], 'Late-Breaking': [493], 'Research);': [494], '2023': [495], 'Apr': [496], '14-19;': [497], 'Orlando,': [498], 'FL.': [499], 'Philadelphia': [500], '(PA):': [501], 'AACR;': [502], 'Res': [504], '2023;83(8_Suppl):Abstract': [505], 'nr': [506], 'CT098.': [507]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4365513192', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}], 'updated_date': '2024-12-30T10:08:00.640038', 'created_date': '2023-04-15'}
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