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['https://openalex.org/W2042034004', 'https://openalex.org/W2101962994', 'https://openalex.org/W2271777283', 'https://openalex.org/W2532034722'], 'related_works': ['https://openalex.org/W4382771775', 'https://openalex.org/W4362509846', 'https://openalex.org/W3109505888', 'https://openalex.org/W2493937886', 'https://openalex.org/W2417456640', 'https://openalex.org/W2379373599', 'https://openalex.org/W2348615003', 'https://openalex.org/W2329701331', 'https://openalex.org/W2300525357', 'https://openalex.org/W103021685'], 'abstract_inverted_index': {'一酸化炭素carbon': [0], 'monoxide(CO)中毒による肺傷害は稀である。練炭によるCO中毒で急性呼吸窮迫症候群acute': [1], 'respiratory': [2], 'distress': [3], 'syndrome(ARDS)を併発した1例を報告する。': [4], '本論文は倫理委員会の承諾を要しない。個人情報保護法に基づいて匿名化され,患者より論文出版の同意を得た。': [5], '患': [6], '者:既往や服薬のない59歳の女性。身長163cm,体重59kg。': [7], '現病歴:浴室でコンロに入れた練炭に着火,4時間後に座ったまま意識がない状態で発見され救急搬送された。': [8], '来院時現症:GCS': [9], 'E1V2M4,心拍数90/分,血圧103/55mmHg,呼吸数26/分,SpO2': [10], '77%(室内気),体温35.7℃,熱傷はなかった。': [11], '検査所見:CRP': [12], '0mg/dL,WBC': [13], '5,900/µL,CK': [14], '83IU/L,トロポニンI': [15], '0.01ng/mL,動脈血液ガス(リザーバーマスク15L/分)pH': [16], '7.301,PaCO2': [17], '33.7mmHg,PaO2': [18], '262mmHg,CO–Hb': [19], '25.2%。心電図は異常なく,CT検査で両側上葉中心に粒状影を伴うスリガラス影を認めた(Fig.': [20], '1a–c)。': [21], 'Chest': [22], 'computed': [23], 'tomography': [24], 'on': [25], 'days': [26], '1': [27], '(a–c)': [28, 32], 'and': [29, 44, 54], '2': [30], '(d–f).': [31], 'showed': [33, 46], 'ground–glass': [34], 'opacity': [35], 'in': [36, 50], 'the': [37, 40, 51], 'center': [38], 'of': [39], 'bilateral': [41, 52], 'upper': [42, 53], 'lobes': [43], '(d–f)': [45], 'extensive': [47], 'consolidation': [48], 'mainly': [49], 'middle': [55], 'lobes.': [56], '来院後経過:酸素投与でCO–Hbは速やかに低下し意識は回復した。第2病日にP/F比80で挿管,人工呼吸管理となった。CTで両側上中肺野中心にびまん性浸潤影を認め(Fig.': [57], '1d–f),心エコー検査は異常なく,微生物学的検査で有意な細菌を認めなかった。気管支鏡検査で上葉枝中心に粘膜発赤を認め,肺胞洗浄液検査(回収率36.5%)で細胞数235/µL,好中球80%,好酸球3%,リンパ球3%と好中球著増から,呼吸不全の原因としてCO中毒によるARDSを疑った。肺胞洗浄液検査結果判明まで好酸球性肺炎を念頭に,メチルプレドニゾロン40mgを6時間ごとに投与した。抗菌薬投与はなかった。第3病日にP/F比は200に改善し抜管,第13病日に退院した。': [58], '本症例は,心原性肺水腫,誤嚥・細菌性肺炎が否定的で,CO中毒によるARDSと診断した。': [59], 'CO中毒では,心筋障害による肺水腫,火災の煙による肺傷害が知られる': [60], '1が,非火災例の肺傷害の報告はほとんどない。排気ガスのCO中毒で死亡した27歳の女性は,両側肺浸潤影,低い肺動脈楔入圧,病理解剖での肺胞出血と硝子膜形成を伴う肺水腫,上皮細胞損傷からARDSと診断され,同報告の動物実験でCOによる肺胞上皮透過性亢進を認めた': [61], '2。CO中毒567例の剖検で半数以上が肺水腫と肺胞出血を,電子顕微鏡検査施行例の1/3で肺胞内の好中球浸潤を認め': [62], '3,重症CO中毒に伴うARDSは過小評価されている可能性がある。COの内皮機能不全とフリーラジカル産生増加': [63], '1,肺胞液クリアランスの低下': [64], '4は,ARDS発症と関連する可能性がある。': [65], 'CO中毒はARDSを惹起する可能性がある。': [66], '本報告における利益相反はない。': [67], '本報告は第49回日本集中治療医学会学術集会(仙台)で発表した。': [68]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4362509846', 'counts_by_year': [], 'updated_date': '2024-12-10T07:32:00.003464', 'created_date': '2023-04-06'}