Title: eFigure 2 from Amphiregulin Expression Is a Predictive Biomarker for <i>EGFR</i> Inhibition in Metastatic Colorectal Cancer: Combined Analysis of Three Randomized Trials
Abstract: <p>Data distribution of amphiregulin (AREG) and epiregulin (EREG) mRNA expression in the three randomized controlled trials FIRE-1, CIOX and FIRE-3. Logarithmic mRNA expression of AREG (A) was parametric distributed and could be normalized to a homogenous collective on which consistent threshold values could be applied (B). Logarithmic mRNA expression of EREG was non-parametric distributed (C) and could not be normalized to a homogenous collective (D)</p>