Abstract: We retrospectively analyzed a cohort of 11 patients with a history of prior low dose rate brachytherapy who were treated with homogeneously dosed salvage stereotactic body radiotherapy (SBRT).Three-year progressionfree survival and overall survival were 70.1% and 100%, respectively.Late grade 2 and 3 genitourinary toxicity rates were 36.4% and 9.1%, respectively.Homogeneously dosed prostate SBRT can serve as a safe and effective salvage treatment for local recurrences following LDR brachytherapy.