Publication Information

{'id': 'https://openalex.org/W4360607857', 'doi': 'https://doi.org/10.1097/ju.0000000000003332.06', 'title': 'MP69-06 CHARACTERISTICS OF UPPER URINARY TRACT UROTHELIAL CARCINOMA DEFICIENT IN LYNCH SYNDROME-RELATED MISMATCH REPAIR GENE EXPRESSION PROTEIN ON IMMUNOHISTOCHEMISTRY', 'display_name': 'MP69-06 CHARACTERISTICS OF UPPER URINARY TRACT UROTHELIAL CARCINOMA DEFICIENT IN LYNCH SYNDROME-RELATED MISMATCH REPAIR GENE EXPRESSION PROTEIN ON IMMUNOHISTOCHEMISTRY', 'publication_year': 2023, 'publication_date': '2023-03-23', 'ids': {'openalex': 'https://openalex.org/W4360607857', 'doi': 'https://doi.org/10.1097/ju.0000000000003332.06'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/ju.0000000000003332.06', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5046391729', 'display_name': 'Kenji Tanabe', 'orcid': 'https://orcid.org/0000-0003-2645-9429'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Tanabe Kenji', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022477543', 'display_name': 'Yasukazu Nakanishi', 'orcid': 'https://orcid.org/0000-0002-0536-4335'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Nakanishi Yasukazu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064780711', 'display_name': 'Yasujima Rikuto', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yasujima Rikuto', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113812969', 'display_name': 'Kohei Hirose', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Hirose Kohei', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049933030', 'display_name': 'Umino Yosuke', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Umino Yosuke', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013154516', 'display_name': 'Okubo Naoya', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Okubo Naoya', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077880103', 'display_name': 'Madoka Kataoka', 'orcid': 'https://orcid.org/0000-0001-9084-7798'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kataoka Madoka', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048704012', 'display_name': 'Miyazaki Saori', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Miyazaki Saori', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089761520', 'display_name': 'Yajima Shugo', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yajima Shugo', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046439279', 'display_name': 'Takeshi Kuwata', 'orcid': 'https://orcid.org/0000-0003-0044-953X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kuwata Takeshi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025449135', 'display_name': 'Reiko Watanabe', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Watanabe Reiko', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5048350768', 'display_name': 'Hitoshi Masuda', 'orcid': 'https://orcid.org/0000-0002-9182-8481'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Masuda Hitoshi', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 68}, 'biblio': {'volume': '209', 'issue': 'Supplement 4', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11369', 'display_name': 'Genetic factors in colorectal cancer', 'score': 0.9892, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11369', 'display_name': 'Genetic factors in colorectal cancer', 'score': 0.9892, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pms2', 'display_name': 'PMS2', 'score': 0.8399246}, {'id': 'https://openalex.org/keywords/lynch-syndrome', 'display_name': 'Lynch Syndrome', 'score': 0.74631214}, {'id': 'https://openalex.org/keywords/mlh1', 'display_name': 'MLH1', 'score': 0.7184013}, {'id': 'https://openalex.org/keywords/msh2', 'display_name': 'MSH2', 'score': 0.69217706}], 'concepts': [{'id': 'https://openalex.org/C2778677574', 'wikidata': 'https://www.wikidata.org/wiki/Q18030629', 'display_name': 'PMS2', 'level': 5, 'score': 0.8399246}, {'id': 'https://openalex.org/C2776559941', 'wikidata': 'https://www.wikidata.org/wiki/Q783644', 'display_name': 'Lynch syndrome', 'level': 5, 'score': 0.74631214}, {'id': 'https://openalex.org/C111425858', 'wikidata': 'https://www.wikidata.org/wiki/Q14911708', 'display_name': 'MLH1', 'level': 5, 'score': 0.7184013}, {'id': 'https://openalex.org/C2779115348', 'wikidata': 'https://www.wikidata.org/wiki/Q14911688', 'display_name': 'MSH2', 'level': 5, 'score': 0.69217706}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6854522}, {'id': 'https://openalex.org/C60748783', 'wikidata': 'https://www.wikidata.org/wiki/Q2984243', 'display_name': 'DNA mismatch repair', 'level': 4, 'score': 0.62735146}, {'id': 'https://openalex.org/C3019882237', 'wikidata': 'https://www.wikidata.org/wiki/Q2501186', 'display_name': 'Urothelial carcinoma', 'level': 4, 'score': 0.5208678}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.48517638}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.41314137}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29321116}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.06413165}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/ju.0000000000003332.06', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.44, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4323820886', 'https://openalex.org/W4232081770', 'https://openalex.org/W3025648181', 'https://openalex.org/W3025075020', 'https://openalex.org/W3024264903', 'https://openalex.org/W2586543502', 'https://openalex.org/W2150712145', 'https://openalex.org/W2094774960', 'https://openalex.org/W2093026817', 'https://openalex.org/W2089843864'], 'abstract_inverted_index': {'You': [0], 'have': [1, 221], 'accessJournal': [2], 'of': [3, 210, 273, 304, 402, 443, 477, 505, 513, 519, 531], 'UrologyCME1': [4], 'Apr': [5], '2023MP69-06': [6], 'CHARACTERISTICS': [7], 'OF': [8], 'UPPER': [9], 'URINARY': [10], 'TRACT': [11], 'UROTHELIAL': [12], 'CARCINOMA': [13], 'DEFICIENT': [14], 'IN': [15], 'LYNCH': [16], 'SYNDROME-RELATED': [17], 'MISMATCH': [18], 'REPAIR': [19], 'GENE': [20], 'EXPRESSION': [21], 'PROTEIN': [22], 'ON': [23], 'IMMUNOHISTOCHEMISTRY': [24], 'Tanabe': [25, 50, 564], 'Kenji,': [26], 'Nakanishi': [27, 59, 571], 'Yasukazu,': [28], 'Yasujima': [29, 68, 578], 'Rikuto,': [30], 'Hirose': [31, 77, 585], 'Kohei,': [32], 'Umino': [33, 86, 592], 'Yosuke,': [34], 'Okubo': [35, 95, 599], 'Naoya,': [36], 'Kataoka': [37, 104, 606], 'Madoka,': [38], 'Miyazaki': [39, 113, 613], 'Saori,': [40], 'Yajima': [41, 122, 620], 'Shugo,': [42], 'Kuwata': [43, 131, 627], 'Takeshi,': [44], 'Watanabe': [45, 140, 634], 'Reiko,': [46], 'and': [47, 149, 220, 266, 286, 313, 318, 346, 353, 372, 394, 525, 541, 560], 'Masuda': [48, 150, 641], 'Hitoshi': [49, 152, 642], 'KenjiTanabe': [51], 'Kenji': [52, 565], 'More': [53, 62, 71, 80, 89, 98, 107, 116, 125, 134, 143, 153, 566, 573, 580, 587, 594, 601, 608, 615, 622, 629, 636, 643], 'articles': [54, 63, 72, 81, 90, 99, 108, 117, 126, 135, 144, 154, 567, 574, 581, 588, 595, 602, 609, 616, 623, 630, 637, 644], 'by': [55, 64, 73, 82, 91, 100, 109, 118, 127, 136, 145, 155, 311, 536, 555, 568, 575, 582, 589, 596, 603, 610, 617, 624, 631, 638, 645], 'this': [56, 65, 74, 83, 92, 101, 110, 119, 128, 137, 146, 156, 253, 300, 569, 576, 583, 590, 597, 604, 611, 618, 625, 632, 639, 646], 'author': [57, 66, 75, 84, 93, 102, 111, 120, 129, 138, 147, 157, 570, 577, 584, 591, 598, 605, 612, 619, 626, 633, 640, 647], ',': [58, 67, 76, 85, 94, 103, 112, 121, 130, 139, 148], 'YasukazuNakanishi': [60], 'Yasukazu': [61, 572], 'RikutoYasujima': [69], 'Rikuto': [70, 579], 'KoheiHirose': [78], 'Kohei': [79, 586], 'YosukeUmino': [87], 'Yosuke': [88, 593], 'NaoyaOkubo': [96], 'Naoya': [97, 600], 'MadokaKataoka': [105], 'Madoka': [106, 607], 'SaoriMiyazaki': [114], 'Saori': [115, 614], 'ShugoYajima': [123], 'Shugo': [124, 621], 'TakeshiKuwata': [132], 'Takeshi': [133, 628], 'ReikoWatanabe': [141], 'Reiko': [142, 635], 'HitoshiMasuda': [151], 'View': [158], 'All': [159, 649], 'Author': [160], 'Informationhttps://doi.org/10.1097/JU.0000000000003332.06AboutPDF': [161], 'ToolsAdd': [162], 'to': [163, 200, 214, 330, 380, 406], 'favoritesDownload': [164], 'CitationsTrack': [165], 'CitationsPermissionsReprints': [166], 'ShareFacebookLinked': [167], 'InTwitterEmail': [168], 'Abstract': [169], 'INTRODUCTION': [170], 'AND': [171], 'OBJECTIVE:': [172], 'Lynch': [173], 'syndrome': [174, 186], '(LS)': [175], 'is': [176, 183, 212, 235], 'an': [177], 'autosomal': [178], 'formed': [179], 'inherited': [180], 'disorder': [181], 'that': [182, 239], 'a': [184, 207, 217, 222, 475, 527], 'susceptibility': [185], 'for': [187, 368, 375], 'several': [188], 'cancers.': [189], 'Four': [190], 'mismatch': [191], 'repair': [192], '(MMR)': [193], 'genes': [194], '(MLH1,': [195], 'MSH2/6,': [196], 'PMS2)': [197], 'are': [198, 248], 'thought': [199], 'be': [201, 331, 407, 509], 'involved': [202], 'in': [203, 244, 264, 299, 333, 344, 350, 409, 423, 488, 499, 521], 'LS.': [204], 'Colorectal': [205], 'cancer,': [206], 'representative': [208], 'cancer': [209, 238, 404, 479], 'LS,': [211, 245], 'known': [213], 'develop': [215], 'at': [216, 289], 'younger': [218], 'age': [219, 364], 'better': [223], 'prognosis': [224], 'than': [225, 359], 'non-LS': [226], 'colorectal': [227, 478, 515], 'cancer.': [228, 516], 'Upper': [229], 'urinary': [230], 'tract': [231], 'urothelial': [232], 'carcinoma': [233], '(UTUC)': [234], 'third': [236], 'major': [237], 'occur': [240], 'with': [241, 277, 316, 474, 483], 'increased': [242], 'frequency': [243], 'but': [246, 466, 496], 'details': [247], 'not': [249, 461, 491], 'well': [250], 'known.': [251], 'In': [252], 'study,': [254], 'we': [255], 'examined': [256, 310], 'MMR': [257, 306, 335, 456, 469], 'gene-related': [258, 307, 336, 447], 'protein': [259, 337, 448], 'defects': [260], 'on': [261, 338], 'immunohistochemistry': [262], '(IHC)': [263], 'UTUC': [265, 278, 507, 522], 'analyzed': [267, 322], 'their': [268], 'characteristics.': [269], 'METHODS:': [270], 'A': [271], 'total': [272], '150': [274, 435], 'consecutive': [275], 'patients': [276, 326, 341, 459], 'who': [279, 485], 'underwent': [280], 'surgical': [281], 'resection': [282], 'between': [283, 429], 'February': [284], '2012': [285], 'December': [287], '2020': [288], 'National': [290], 'Cancer': [291], 'Center': [292], 'Hospital': [293], 'East': [294], '(Chiba,': [295], 'Japan)': [296], 'were': [297, 328, 342, 420], 'included': [298], 'study.': [301, 529], 'The': [302, 362, 503, 517], 'expression': [303], 'four': [305], 'proteins': [308], 'was': [309, 321, 365, 480, 497], 'IHC,': [312], 'the': [314, 369, 376, 381, 384, 410, 430, 434, 451], 'association': [315], 'clinical': [317], 'oncological': [319, 427], 'characteristics': [320, 425, 504], 'retrospectively.': [323], 'RESULTS:': [324], 'Six': [325], '(4%)': [327], 'found': [329], 'deficient': [332, 343, 498], 'some': [334, 468], 'IHC.': [339], 'Three': [340], 'MSH2': [345, 446], 'one': [347], 'patient': [348, 356, 473], 'each': [349], 'MLH1,': [351, 489], 'MSH6': [352], 'PMS2.': [354], 'No': [355], 'had': [357, 387, 454, 486], 'more': [358, 388, 408], '2': [360], 'deficiencies.': [361], 'median': [363], '74': [366], 'years': [367, 374], 'MMR-deficient': [370, 385, 411], 'group': [371, 386, 412], '72': [373], 'non-deficient': [377, 382], 'group.': [378], 'Compared': [379], 'group,': [383], 'female': [389, 472], '(83%': [390], 'vs': [391, 398, 414], '26%;': [392], 'p=0.0025)': [393], 'right-side': [395], 'tumor': [396], '(100%': [397], '44%;': [399], 'p=0.0075).': [400], 'History': [401], 'LS-related': [403, 506, 514], 'tended': [405], '(33%': [413], '9%;': [415], 'p=0.051).': [416], '(Table': [417], '1)': [418], 'There': [419], 'no': [421, 455], 'differences': [422], 'pathologic': [424], 'nor': [426], 'outcome': [428], 'two': [431], 'groups.': [432], 'Of': [433], 'patients,': [436], '4': [437], 'met': [438], 'Amsterdam': [439, 463, 493], 'Criteria': [440, 464, 494], 'II.': [441], 'One': [442, 471], 'them': [444], 'showed': [445, 467], 'defects,': [449], 'while': [450], 'other': [452], 'three': [453], 'defects.': [457], 'Five': [458], 'did': [460, 490], 'meet': [462, 492], 'II': [465], 'defect.': [470], 'history': [476], 'genetically': [481], 'diagnosed': [482], 'LS': [484, 520], 'mutation': [487], 'II,': [495], 'MLH1-related': [500], 'protein.': [501], 'CONCLUSIONS:': [502], 'may': [508], 'different': [510], 'from': [511], 'those': [512], 'impact': [518], 'remains': [523], 'unclear': [524], 'requires': [526], 'large-scale': [528], 'Source': [530], 'Funding:': [532], 'None': [533], '©': [534], '2023': [535, 554], 'American': [537, 556], 'Urological': [538, 557], 'Association': [539, 558], 'Education': [540, 559], 'Research,': [542, 561], 'Inc.FiguresReferencesRelatedDetails': [543], 'Volume': [544], '209Issue': [545], 'Supplement': [546], '4April': [547], '2023Page:': [548], 'e965': [549], 'Advertisement': [550, 650], 'Copyright': [551], '&': [552], 'Permissions©': [553], 'Inc.MetricsAuthor': [562], 'Information': [563], 'Expand': [648], 'PDF': [651], 'downloadLoading': [652], '...': [653]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4360607857', 'counts_by_year': [], 'updated_date': '2024-12-08T03:00:21.711515', 'created_date': '2023-03-24'}