Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4322720888', 'doi': 'https://doi.org/10.1016/j.canlet.2023.216108', 'title': 'Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance', 'display_name': 'Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance', 'publication_year': 2023, 'publication_date': '2023-03-02', 'ids': {'openalex': 'https://openalex.org/W4322720888', 'doi': 'https://doi.org/10.1016/j.canlet.2023.216108', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36863506'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.canlet.2023.216108', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S106234763', 'display_name': 'Cancer Letters', 'issn_l': '0304-3835', 'issn': ['0304-3835', '1872-7980'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5043310855', 'display_name': 'Jianfeng Peng', 'orcid': 'https://orcid.org/0000-0002-1379-4773'}, 'institutions': [{'id': 'https://openalex.org/I4210100830', 'display_name': 'Shandong Tumor Hospital', 'ror': 'https://ror.org/01413r497', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100830']}, {'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianfeng Peng', 'raw_affiliation_strings': ['Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China', 'institution_ids': ['https://openalex.org/I4210100830', 'https://openalex.org/I4210163399']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101908381', 'display_name': 'Xiaoyan Yin', 'orcid': 'https://orcid.org/0000-0001-5103-5500'}, 'institutions': [{'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}, {'id': 'https://openalex.org/I4210100830', 'display_name': 'Shandong Tumor Hospital', 'ror': 'https://ror.org/01413r497', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100830']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaoyan Yin', 'raw_affiliation_strings': ['Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China', 'institution_ids': ['https://openalex.org/I4210163399', 'https://openalex.org/I4210100830']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015677251', 'display_name': 'Wenhua Yun', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}, {'id': 'https://openalex.org/I4210100830', 'display_name': 'Shandong Tumor Hospital', 'ror': 'https://ror.org/01413r497', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100830']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenhua Yun', 'raw_affiliation_strings': ['Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China', 'institution_ids': ['https://openalex.org/I4210163399', 'https://openalex.org/I4210100830']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074306070', 'display_name': 'Xiangjiao Meng', 'orcid': 'https://orcid.org/0000-0003-2737-5905'}, 'institutions': [{'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}, {'id': 'https://openalex.org/I4210100830', 'display_name': 'Shandong Tumor Hospital', 'ror': 'https://ror.org/01413r497', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100830']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xiangjiao Meng', 'raw_affiliation_strings': ['Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China', 'institution_ids': ['https://openalex.org/I4210163399', 'https://openalex.org/I4210100830']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101724814', 'display_name': 'Zhaoqin Huang', 'orcid': 'https://orcid.org/0000-0002-2069-3401'}, 'institutions': [{'id': 'https://openalex.org/I4210116517', 'display_name': 'Shandong Provincial Hospital', 'ror': 'https://ror.org/02ar2nf05', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210116517']}, {'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zhaoqin Huang', 'raw_affiliation_strings': ['Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China', 'institution_ids': ['https://openalex.org/I4210116517', 'https://openalex.org/I4210163399']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5074306070', 'https://openalex.org/A5101724814'], 'corresponding_institution_ids': ['https://openalex.org/I4210163399', 'https://openalex.org/I4210100830', 'https://openalex.org/I4210116517', 'https://openalex.org/I4210163399'], 'apc_list': {'value': 4100, 'currency': 'USD', 'value_usd': 4100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.525, 'has_fulltext': False, 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.99927, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '559', 'issue': None, 'first_page': '216108', 'last_page': '216108'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11313', 'display_name': 'Immune cells in cancer', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.8679981}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.83752227}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.6500428}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.56717145}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.53505737}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.4070537}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3260539}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.21416065}], 'mesh': [{'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000082082', 'descriptor_name': 'Immune Checkpoint Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000082082', 'descriptor_name': 'Immune Checkpoint Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000082082', 'descriptor_name': 'Immune Checkpoint Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007167', 'descriptor_name': 'Immunotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000532', 'qualifier_name': 'radiotherapy', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.canlet.2023.216108', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S106234763', 'display_name': 'Cancer Letters', 'issn_l': '0304-3835', 'issn': ['0304-3835', '1872-7980'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36863506', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.84, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '82272845'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81972796'}, {'funder': 'https://openalex.org/F4320324174', 'funder_display_name': 'Natural Science Foundation of Shandong Province', 'award_id': 'ZR2019MH010'}, {'funder': 'https://openalex.org/F4320324174', 'funder_display_name': 'Natural Science Foundation of Shandong Province', 'award_id': 'ZR2020MH289'}], 'datasets': [], 'versions': [], 'referenced_works_count': 184, 'referenced_works': ['https://openalex.org/W1495108757', 'https://openalex.org/W1661176175', 'https://openalex.org/W1850692467', 'https://openalex.org/W1866104439', 'https://openalex.org/W1876890400', 'https://openalex.org/W1883506207', 'https://openalex.org/W1963965619', 'https://openalex.org/W1968012290', 'https://openalex.org/W1968208029', 'https://openalex.org/W1972189148', 'https://openalex.org/W1978496495', 'https://openalex.org/W1978577068', 'https://openalex.org/W1985830305', 'https://openalex.org/W1986986101', 'https://openalex.org/W1991370659', 'https://openalex.org/W1991570175', 'https://openalex.org/W1991615518', 'https://openalex.org/W1993016627', 'https://openalex.org/W1993778132', 'https://openalex.org/W1994325381', 'https://openalex.org/W1995703832', 'https://openalex.org/W2002244802', 'https://openalex.org/W2007369689', 'https://openalex.org/W2009298572', 'https://openalex.org/W2009867248', 'https://openalex.org/W2024250498', 'https://openalex.org/W2024315189', 'https://openalex.org/W2026506883', 'https://openalex.org/W2028066677', 'https://openalex.org/W2037342985', 'https://openalex.org/W2038436501', 'https://openalex.org/W2043967411', 'https://openalex.org/W2045295282', 'https://openalex.org/W2047849482', 'https://openalex.org/W2050261141', 'https://openalex.org/W2052727153', 'https://openalex.org/W2053393698', 'https://openalex.org/W2054067663', 'https://openalex.org/W2058229406', 'https://openalex.org/W2058344600', 'https://openalex.org/W2062664804', 'https://openalex.org/W2068290193', 'https://openalex.org/W2075331783', 'https://openalex.org/W2075879891', 'https://openalex.org/W2086080780', 'https://openalex.org/W2086310075', 'https://openalex.org/W2087752435', 'https://openalex.org/W2092482969', 'https://openalex.org/W2094025663', 'https://openalex.org/W2097471654', 'https://openalex.org/W2099052265', 'https://openalex.org/W2100303404', 'https://openalex.org/W2100409677', 'https://openalex.org/W2105713954', 'https://openalex.org/W2105989630', 'https://openalex.org/W2107338023', 'https://openalex.org/W2109424201', 'https://openalex.org/W2110344693', 'https://openalex.org/W2111547416', 'https://openalex.org/W2117002945', 'https://openalex.org/W2117058819', 'https://openalex.org/W2117878645', 'https://openalex.org/W2119423559', 'https://openalex.org/W2121391430', 'https://openalex.org/W2122940327', 'https://openalex.org/W2124104087', 'https://openalex.org/W2125150261', 'https://openalex.org/W2130273337', 'https://openalex.org/W2131235217', 'https://openalex.org/W2132564070', 'https://openalex.org/W2134623662', 'https://openalex.org/W2137478279', 'https://openalex.org/W2138300993', 'https://openalex.org/W2140741923', 'https://openalex.org/W2141592196', 'https://openalex.org/W2143839116', 'https://openalex.org/W2145121495', 'https://openalex.org/W2146905485', 'https://openalex.org/W2149360266', 'https://openalex.org/W2152823597', 'https://openalex.org/W2153840858', 'https://openalex.org/W2153856358', 'https://openalex.org/W2156480607', 'https://openalex.org/W2157407457', 'https://openalex.org/W2163187600', 'https://openalex.org/W2168973302', 'https://openalex.org/W2169090653', 'https://openalex.org/W2169841382', 'https://openalex.org/W2233610963', 'https://openalex.org/W2243702269', 'https://openalex.org/W2292016096', 'https://openalex.org/W2309177734', 'https://openalex.org/W2318433546', 'https://openalex.org/W2471536144', 'https://openalex.org/W2512899508', 'https://openalex.org/W2513294073', 'https://openalex.org/W2528843175', 'https://openalex.org/W2561101222', 'https://openalex.org/W2562305489', 'https://openalex.org/W2587048937', 'https://openalex.org/W2587143085', 'https://openalex.org/W2608932173', 'https://openalex.org/W2609252780', 'https://openalex.org/W2610224116', 'https://openalex.org/W2618173228', 'https://openalex.org/W2628566439', 'https://openalex.org/W2730718150', 'https://openalex.org/W2757800870', 'https://openalex.org/W2765195830', 'https://openalex.org/W2765750933', 'https://openalex.org/W2773728373', 'https://openalex.org/W2783111873', 'https://openalex.org/W2783581317', 'https://openalex.org/W2787553571', 'https://openalex.org/W2790651932', 'https://openalex.org/W2794164629', 'https://openalex.org/W2794316390', 'https://openalex.org/W2800123018', 'https://openalex.org/W2807798312', 'https://openalex.org/W2885000766', 'https://openalex.org/W2888484680', 'https://openalex.org/W2890822303', 'https://openalex.org/W2896737957', 'https://openalex.org/W2903196192', 'https://openalex.org/W2903791264', 'https://openalex.org/W2904712055', 'https://openalex.org/W2906371753', 'https://openalex.org/W2910867684', 'https://openalex.org/W2911526204', 'https://openalex.org/W2916372295', 'https://openalex.org/W2916385204', 'https://openalex.org/W2939856144', 'https://openalex.org/W2951890476', 'https://openalex.org/W2963034931', 'https://openalex.org/W2963936065', 'https://openalex.org/W2967380313', 'https://openalex.org/W2973152655', 'https://openalex.org/W2975233607', 'https://openalex.org/W2983897056', 'https://openalex.org/W2995607278', 'https://openalex.org/W2995956442', 'https://openalex.org/W3003051803', 'https://openalex.org/W3004060585', 'https://openalex.org/W3004431118', 'https://openalex.org/W3006010054', 'https://openalex.org/W3015321859', 'https://openalex.org/W3015983644', 'https://openalex.org/W3039120173', 'https://openalex.org/W3041459808', 'https://openalex.org/W3047845937', 'https://openalex.org/W3069403444', 'https://openalex.org/W3079553558', 'https://openalex.org/W3080164745', 'https://openalex.org/W3080399909', 'https://openalex.org/W3081224935', 'https://openalex.org/W3091342774', 'https://openalex.org/W3094422108', 'https://openalex.org/W3097206347', 'https://openalex.org/W3097531118', 'https://openalex.org/W3099561206', 'https://openalex.org/W3101467937', 'https://openalex.org/W3108819942', 'https://openalex.org/W3113549876', 'https://openalex.org/W3132259578', 'https://openalex.org/W3133734054', 'https://openalex.org/W3138805442', 'https://openalex.org/W3162899657', 'https://openalex.org/W3163351308', 'https://openalex.org/W3204489057', 'https://openalex.org/W3204707855', 'https://openalex.org/W3207246837', 'https://openalex.org/W3214278893', 'https://openalex.org/W4200289963', 'https://openalex.org/W4205937413', 'https://openalex.org/W4210549928', 'https://openalex.org/W4213359935', 'https://openalex.org/W4214632897', 'https://openalex.org/W4223575919', 'https://openalex.org/W4224010473', 'https://openalex.org/W4244055564', 'https://openalex.org/W4281760394', 'https://openalex.org/W4286498606', 'https://openalex.org/W4303628882', 'https://openalex.org/W4307886203'], 'related_works': ['https://openalex.org/W4322720888', 'https://openalex.org/W4307869277', 'https://openalex.org/W4296613612', 'https://openalex.org/W4206801305', 'https://openalex.org/W4200022043', 'https://openalex.org/W3193904228', 'https://openalex.org/W2884525857', 'https://openalex.org/W2355955825', 'https://openalex.org/W2112727616', 'https://openalex.org/W2056534599'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4322720888', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 2}], 'updated_date': '2025-01-08T21:51:23.170132', 'created_date': '2023-03-03'}