Publication Information

{'id': 'https://openalex.org/W4313648124', 'doi': 'https://doi.org/10.1002/jev2.12300', 'title': 'Identification of faecal extracellular vesicles as novel biomarkers for the non‐invasive diagnosis and prognosis of colorectal cancer', 'display_name': 'Identification of faecal extracellular vesicles as novel biomarkers for the non‐invasive diagnosis and prognosis of colorectal cancer', 'publication_year': 2023, 'publication_date': '2023-01-01', 'ids': {'openalex': 'https://openalex.org/W4313648124', 'doi': 'https://doi.org/10.1002/jev2.12300', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36604402'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jev2.12300', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jev2.12300', 'source': {'id': 'https://openalex.org/S2764464234', 'display_name': 'Journal of Extracellular Vesicles', 'issn_l': '2001-3078', 'issn': ['2001-3078'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jev2.12300', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100683821', 'display_name': 'Zhaowei Zhang', 'orcid': 'https://orcid.org/0009-0002-6741-9546'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4391767646', 'display_name': 'State Key Laboratory of Medicinal Chemical Biology', 'ror': 'https://ror.org/032p70522', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhaowei Zhang', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100722799', 'display_name': 'Xuehui Liu', 'orcid': 'https://orcid.org/0000-0001-8987-6145'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4391767646', 'display_name': 'State Key Laboratory of Medicinal Chemical Biology', 'ror': 'https://ror.org/032p70522', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}, {'id': 'https://openalex.org/I151075929', 'display_name': 'Army Medical University', 'ror': 'https://ror.org/05w21nn13', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I151075929']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xuehui Liu', 'raw_affiliation_strings': ['College of Pharmacy, Third Military Medical University, Chongqing, China', 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}, {'raw_affiliation_string': 'College of Pharmacy, Third Military Medical University, Chongqing, China', 'institution_ids': ['https://openalex.org/I151075929']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108378639', 'display_name': 'Xiaoqing Yang', 'orcid': 'https://orcid.org/0000-0001-5808-4380'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}, {'id': 'https://openalex.org/I4210133270', 'display_name': 'Second Hospital of Tianjin Medical University', 'ror': 'https://ror.org/03rc99w60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133270']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaoqing Yang', 'raw_affiliation_strings': ['Tianjin Institute of Urology, the 2nd Hospital of Tianjin Medical University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Tianjin Institute of Urology, the 2nd Hospital of Tianjin Medical University, Tianjin, China', 'institution_ids': ['https://openalex.org/I5740404', 'https://openalex.org/I4210133270']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101686886', 'display_name': 'Ying Jiang', 'orcid': 'https://orcid.org/0000-0003-3253-6400'}, 'institutions': [{'id': 'https://openalex.org/I4391767646', 'display_name': 'State Key Laboratory of Medicinal Chemical Biology', 'ror': 'https://ror.org/032p70522', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}, {'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ying Jiang', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I4391767646', 'https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100413574', 'display_name': 'Ang Li', 'orcid': 'https://orcid.org/0000-0001-6720-0785'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4391767646', 'display_name': 'State Key Laboratory of Medicinal Chemical Biology', 'ror': 'https://ror.org/032p70522', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ang Li', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000489675', 'display_name': 'Jiying Cong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiying Cong', 'raw_affiliation_strings': ['Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100331387', 'display_name': 'Yuwei Li', 'orcid': 'https://orcid.org/0000-0002-5488-242X'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuwei Li', 'raw_affiliation_strings': ['Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054566753', 'display_name': 'Qinjian Xie', 'orcid': None}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qinjian Xie', 'raw_affiliation_strings': ['Gansu Corps Hospital of CAPF, Lanzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Gansu Corps Hospital of CAPF, Lanzhou, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017405439', 'display_name': 'Chen Xu', 'orcid': 'https://orcid.org/0000-0002-2862-7943'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Chen Xu', 'raw_affiliation_strings': ['Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin Institute of Coloproctology, School of Medicine, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5073380623', 'display_name': 'Dingbin Liu', 'orcid': 'https://orcid.org/0000-0003-4153-9822'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4391767646', 'display_name': 'State Key Laboratory of Medicinal Chemical Biology', 'ror': 'https://ror.org/032p70522', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Dingbin Liu', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279', 'https://openalex.org/I4391767646']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5017405439', 'https://openalex.org/A5073380623'], 'corresponding_institution_ids': ['https://openalex.org/I205237279', 'https://openalex.org/I205237279', 'https://openalex.org/I4391767646'], 'apc_list': {'value': 3850, 'currency': 'USD', 'value_usd': 3850, 'provenance': 'doaj'}, 'apc_paid': {'value': 3850, 'currency': 'USD', 'value_usd': 3850, 'provenance': 'doaj'}, 'fwci': 8.59, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 34, 'citation_normalized_percentile': {'value': 0.99998, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '12', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10773', 'display_name': 'Extracellular vesicles in disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10773', 'display_name': 'Extracellular vesicles in disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11297', 'display_name': 'Ferroptosis and cancer prognosis', 'score': 0.9834, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12387', 'display_name': 'Galectins and Cancer Biology', 'score': 0.9807, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/carcinoembryonic-antigen', 'display_name': 'Carcinoembryonic antigen', 'score': 0.68296725}, {'id': 'https://openalex.org/keywords/extracellular-vesicles', 'display_name': 'Extracellular Vesicles', 'score': 0.6718029}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.78913057}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.76808405}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.7628943}, {'id': 'https://openalex.org/C2777387746', 'wikidata': 'https://www.wikidata.org/wiki/Q769706', 'display_name': 'Carcinoembryonic antigen', 'level': 3, 'score': 0.68296725}, {'id': 'https://openalex.org/C2992929900', 'wikidata': 'https://www.wikidata.org/wiki/Q21097485', 'display_name': 'Extracellular vesicles', 'level': 2, 'score': 0.6718029}, {'id': 'https://openalex.org/C61716771', 'wikidata': 'https://www.wikidata.org/wiki/Q496', 'display_name': 'Feces', 'level': 2, 'score': 0.53196025}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.48649448}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.46756846}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.45375112}, {'id': 'https://openalex.org/C20518536', 'wikidata': 'https://www.wikidata.org/wiki/Q6840469', 'display_name': 'Microvesicles', 'level': 4, 'score': 0.44963288}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.1996668}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.10880625}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015179', 'descriptor_name': 'Colorectal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000067128', 'descriptor_name': 'Extracellular Vesicles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015179', 'descriptor_name': 'Colorectal Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D015179', 'descriptor_name': 'Colorectal Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D000067128', 'descriptor_name': 'Extracellular Vesicles', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005243', 'descriptor_name': 'Feces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jev2.12300', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jev2.12300', 'source': {'id': 'https://openalex.org/S2764464234', 'display_name': 'Journal of Extracellular Vesicles', 'issn_l': '2001-3078', 'issn': ['2001-3078'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816085', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36604402', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jev2.12300', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jev2.12300', 'source': {'id': 'https://openalex.org/S2764464234', 'display_name': 'Journal of Extracellular Vesicles', 'issn_l': '2001-3078', 'issn': ['2001-3078'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.64}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '21977053'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '22174072'}], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1270356811', 'https://openalex.org/W1975310898', 'https://openalex.org/W1992510232', 'https://openalex.org/W2034774921', 'https://openalex.org/W2051240173', 'https://openalex.org/W2051931680', 'https://openalex.org/W2065569711', 'https://openalex.org/W2067183337', 'https://openalex.org/W2099828433', 'https://openalex.org/W2099998407', 'https://openalex.org/W2112940836', 'https://openalex.org/W2118976328', 'https://openalex.org/W2154477723', 'https://openalex.org/W2170908852', 'https://openalex.org/W2191199994', 'https://openalex.org/W2218656852', 'https://openalex.org/W2285205964', 'https://openalex.org/W2401853432', 'https://openalex.org/W2512657527', 'https://openalex.org/W2563111510', 'https://openalex.org/W2765280408', 'https://openalex.org/W2767946106', 'https://openalex.org/W2781579322', 'https://openalex.org/W2790326212', 'https://openalex.org/W2889806779', 'https://openalex.org/W2899663373', 'https://openalex.org/W2964321516', 'https://openalex.org/W2970045605', 'https://openalex.org/W2979443366', 'https://openalex.org/W2983460049', 'https://openalex.org/W2991281216', 'https://openalex.org/W3047244309', 'https://openalex.org/W3087430355', 'https://openalex.org/W3089574950', 'https://openalex.org/W3128646645', 'https://openalex.org/W3135408979', 'https://openalex.org/W3162525297', 'https://openalex.org/W3176014217', 'https://openalex.org/W3183567715', 'https://openalex.org/W4200072015', 'https://openalex.org/W4200487858', 'https://openalex.org/W4212964448', 'https://openalex.org/W4220903131', 'https://openalex.org/W4223611234', 'https://openalex.org/W4225312520', 'https://openalex.org/W4307566731', 'https://openalex.org/W4313648124'], 'related_works': ['https://openalex.org/W4381617892', 'https://openalex.org/W4224608758', 'https://openalex.org/W4224325546', 'https://openalex.org/W4211149832', 'https://openalex.org/W3188041304', 'https://openalex.org/W3128768115', 'https://openalex.org/W2890709780', 'https://openalex.org/W2560295122', 'https://openalex.org/W2247699313', 'https://openalex.org/W2004257346'], 'abstract_inverted_index': {'Abstract': [0], 'Colorectal': [1], 'cancer': [2], '(CRC)': [3], 'is': [4, 12, 73], 'one': [5], 'of': [6, 38, 54, 69, 78, 100, 134, 141, 156, 176, 183, 205], 'the': [7, 17, 36, 47, 52, 64, 76, 98, 109, 120, 154, 166, 174, 180, 186], 'most': [8], 'common': [9], 'malignancies': [10], 'that': [11, 46, 87, 97, 139, 165], 'usually': [13], 'detected': [14], 'late': [15], 'in': [16, 51, 108], 'clinic.': [18], 'The': [19, 93, 127], 'currently': [20], 'available': [21], 'diagnostic': [22], 'tools': [23], 'for': [24, 63, 149, 195], 'CRC': [25, 55, 110, 150, 193, 198], 'are': [26, 88], 'either': [27], 'invasive': [28], 'or': [29], 'insensitive': [30], 'to': [31, 35, 172, 179], 'early': [32], 'lesions': [33], 'due': [34], 'dearth': [37], 'reliable': [39], 'biomarkers.': [40], 'In': [41, 152], 'this': [42], 'study,': [43], 'we': [44], 'discovered': [45], 'extracellular': [48], 'vesicles': [49], '(EVs)': [50], 'faeces': [53, 158], 'patients': [56, 111], 'can': [57, 169], 'act': [58], 'as': [59, 191, 200, 202], 'a': [60, 131, 145], 'potent': [61], 'biomarker': [62, 148], 'non‐invasive': [65, 197], 'diagnosis': [66], 'and': [67, 82, 102], 'prognosis': [68, 175], 'CRC.': [70, 92, 177], 'This': [71], 'finding': [72], 'based': [74], 'on': [75, 104], 'identification': [77], 'two': [79], 'transmembrane': [80], 'proteins—CD147': [81], 'A33—on': [83], 'faeces‐derived': [84], 'EVs': [85, 129], '(fEVs)': [86], 'intrinsically': [89], 'associated': [90], 'with': [91], 'detection': [94], 'results': [95], 'show': [96], 'levels': [99], 'CD147': [101], 'A33': [103], 'fEVs': [105, 168, 188], 'were': [106], 'upregulated': [107], '(': [112, 123, 160], 'n': [113, 124, 161], '=': [114, 125, 162], '48),': [115], 'dramatically': [116], 'distinguishing': [117], 'them': [118], 'from': [119], 'healthy': [121], 'donors': [122], '16).': [126], 'CD147/A33‐enriched': [128, 167, 187], 'offer': [130], 'clinical': [132, 209], 'sensitivity': [133], '89%,': [135], 'much': [136], 'higher': [137], 'than': [138], '(40%)': [140], 'carcinoembryonic': [142], 'antigen': [143], '(CEA),': [144], 'clinically‐established': [146], 'serum': [147], 'diagnosis.': [151], 'addition,': [153], 'analysis': [155], 'longitudinal': [157], 'samples': [159], '29)': [163], 'demonstrated': [164], 'be': [170], 'utilized': [171], 'track': [173], 'Due': [178], 'high': [181], 'compliance': [182], 'faeces‐based': [184], 'detection,': [185], 'could': [189], 'serve': [190], 'new‐generation': [192], 'biomarkers': [194], 'large‐scale,': [196], 'screening': [199], 'well': [201], 'real‐time': [203], 'monitoring': [204], 'patient': [206], 'outcomes': [207], 'during': [208], 'interventions.': [210]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4313648124', 'counts_by_year': [{'year': 2024, 'cited_by_count': 22}, {'year': 2023, 'cited_by_count': 12}], 'updated_date': '2025-01-03T06:21:02.665912', 'created_date': '2023-01-07'}