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[227], 'TsivgoulisGeorgios': [247], 'Correspondence': [249, 2276], 'to:': [250, 1771], 'Tsivgoulis,': [252, 1773], 'MD,': [253, 1774], 'Hospital': [260, 1781], 'Rimini': [261, 1782], '1,': [262, 1783], 'Chaidari,': [263, 1784], '12462,': [264, 1785], 'Email': [266, 1787], 'E-mail': [267], 'Address:': [268], '[email': [269], 'protected]': [270], 'https://orcid.org/0000-0002-0640-3797': [271], 'Originally': [289, 2375], 'published5': [290], 'Jan': [291], '2023https://doi.org/10.1161/STROKEAHA.122.041395Stroke.': [292], '2023;54:e48–e51Other': [293], 'version(s)': [294], 'this': [296, 305, 1570, 1652], 'articleYou': [297], 'are': [298, 318, 359, 922, 970, 979, 1035, 1057, 1214, 1256, 1448, 2178, 2187, 2197, 2202, 2210, 2217, 2237], 'viewing': [299], 'the': [300, 321, 343, 361, 456, 482, 500, 503, 629, 707, 725, 738, 744, 783, 801, 862, 870, 876, 902, 933, 939, 964, 1049, 1064, 1071, 1077, 1090, 1117, 1121, 1126, 1146, 1174, 1215, 1249, 1361, 1369, 1375, 1383, 1414, 1418, 1463, 1492, 1540, 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399, 975, 1396, 1407, 1644], 'CAA': [336, 373, 384, 844, 1235, 1335, 1366, 1647], 'patients.CAA-related': [337], 'TFNEs': [338, 967, 1007, 1056, 1192, 1212, 1255, 1298, 1314, 1400, 1663], 'should': [339, 367, 377, 1243, 1272, 1278, 1470, 1478, 1496, 1536, 2167, 2223, 2265], 'be': [340, 368, 378, 973, 1245, 1273, 1279, 1471, 1479, 1497, 1512, 1537, 1563, 2224, 2233, 2250, 2266], 'considered': [341, 1449], 'differential': [344, 1153], 'diagnosis': [345, 382, 1154, 1189], 'recurrent,': [347, 988], 'stereotyped': [348, 989, 1045], 'episodes': [349, 990, 1046], 'focal': [351, 753, 992, 1267, 1889, 2070], 'neurologic': [352, 1890], 'symptoms': [353, 1011, 1022, 1519], 'characteristic': [355, 1102, 1143], 'spreading': [356, 995, 1014], 'symptomatology.If': [357], 'TFNE': [358], 'suspected,': [360], 'brain': [362, 430, 572, 1109], 'computed': [363, 654, 666, 1110], 'tomography': [364, 655, 1111], 'MRI': [366, 680, 703, 1099, 1140, 1962], 'carefully': [369, 1624], 'evaluated': [370], 'for': [371, 527, 1085, 1344, 1351, 1454, 1481, 1595, 1697, 1722, 1742, 1754, 1816, 2182, 2189], 'possible': [372, 1260, 1619], 'antithrombotic': [375, 1411, 1440], 'treatment': [376, 797], 'avoided': [379, 1480], 'if': [380], 'is': [385, 845, 854, 866, 898, 932, 1083, 1105, 1135, 1150, 1186, 1315, 1385, 1422, 1641], 'made.TFNEs': [386], 'accompanied': [388], 'cSS/cSAH': [389], 'have': [390, 1008, 1340], 'been': [391], 'associated': [392, 1317, 1424], 'higher': [394, 1320, 1404, 1426, 1643], 'risk': [395, 913, 1321, 1343, 1350, 1370, 1384, 1427, 1452, 1530, 1640, 2031, 2080], 'intracranial': [397, 441, 785, 1993], 'hemorrhage': [398, 442, 786, 929, 2083], 'patients': [400, 976, 1005, 1042, 1237, 1295, 1333, 1356, 1367, 1397, 1408, 1522, 1566, 1634, 1645, 1921], 'CAA.A': [402], '71-year-old': [403], 'functionally': [404], 'independent,': [405], 'right-handed': [406], 'man,': [407], 'known': [409], 'dyslipidemia': [410, 1535], 'arterial': [412, 813], 'hypertension': [413], 'presented': [414, 631], 'initially': [415, 1580], 'due': [416, 757], 'transient': [419, 512, 564, 752, 1032, 1505, 1583, 1888], 'episode': [420, 566, 746, 755], 'mixed': [422, 568, 748], 'aphasia,': [423, 634, 1029], 'lasting': [424], '12': [425], 'minutes.': [426], 'The': [427, 506, 560, 713, 888, 1038, 1757, 1811], 'patient': [428, 507, 561, 630, 714, 802, 1182, 1576, 1610, 2008], 'underwent': [429, 571], 'magnetic': [431, 556, 765], 'resonance': [432, 557, 766, 2384], 'imaging': [433, 471, 558, 575, 769, 1285, 1302], '(MRI),': [434], 'which': [435, 931, 1030, 1062], 'excluded': [436, 1513], 'acute': [437, 657, 682, 784, 940, 1464], 'cerebral': [438, 671, 693, 719, 1094, 1161, 1817, 1862, 1923, 1958, 2003, 2033, 2074], 'ischemia': [439], '(ICH).': [443], 'Fluid-attenuated': [444, 599], 'inversion': [445, 600], 'recovery': [446, 601], 'sequences': [447, 462, 577, 603, 618, 771, 1141], 'showed': [448, 586, 620, 656, 817, 1392], 'multiple': [449, 476, 590, 606, 686, 777], '(>10)': [450, 607], 'bilateral,': [451], 'small,': [452], 'hyperintense': [453, 610, 1113], 'lesions': [454, 611, 1088, 1114, 1286, 1303], 'subcortical': [457, 613], 'white': [458, 614], 'matter': [459, 615], 'T2-weighted': [461, 617], 'revealed': [463, 472, 605, 642, 681, 732, 772], 'MRI-visible': [464, 621], 'enlarged': [465, 622], 'periventricular': [466, 623], 'spaces': [467, 624, 1092], 'centrum-semiovale.': [469], 'Susceptibility-weighted': [470, 574, 768], 'linear': [473, 587], 'hypointensities': [474, 588], 'along': [475, 589, 1076, 1089], 'left': [477, 542, 547, 594, 660, 788, 1543], 'cortical': [478, 487, 591, 773, 1079, 1164, 2121], 'regions,': [479], 'mainly': [480], 'parietal': [483, 597], 'lobe,': [484], 'consistent': [485], 'superficial': [488, 774, 1078, 1918, 1954, 2027, 2122], 'siderosis': [489, 775, 1292, 1919, 1955, 2028, 2123], '(cSS;': [490], 'Figure': [491], '1).': [492], 'This': [493, 1081, 1615, 2285], 'neuroimaging': [494, 934, 1103, 1232, 1628, 1859], 'finding': [495], 'was': [496, 508, 550, 704, 715, 750, 798, 803, 827, 952], 'not': [497, 669, 1123, 1623, 2179, 2198, 2211, 2218], 'described': [498], 'report': [501, 1043, 1760], 'from': [502, 945, 1218, 1299, 1752], 'outside': [504], 'institution.': [505], 'diagnosed': [509, 716, 1603], 'ischemic': [513, 1033, 1310, 1506, 1509, 1584, 2153], 'attack': [514], 'treated': [516, 804], 'dual-antiplatelet': [518], 'therapy': [519, 808, 1591], '(clopidogrel': [520], '75': [521, 533], 'mg/day': [522], 'plus': [523], 'acetylsalicylic-acid': [524], '100': [525], 'mg/day)': [526], '21': [528], 'days,': [529, 1052], 'followed': [530], 'by': [531, 857, 987, 1202, 2155], 'clopidogrel': [532], 'mg/day.': [534], 'Due': [535], 'severe': [537, 1429, 1597], '(≥70%),': [538], 'misdiagnosed': [539, 1581], 'as': [540, 958, 1024, 1112, 1224, 1226, 1514, 1582, 1604, 2254], 'symptomatic,': [541], 'internal': [543, 1598], 'carotid': [544, 548, 1593, 1599], 'artery': [545, 1600], 'stenosis,': [546, 1601], 'endarterectomy': [549, 1594], 'performed.Download': [551], 'figureDownload': [552, 761], 'PowerPointFigure': [553, 762], '1.': [554], 'Baseline': [555], '(MRI).': [559], 'experienced': [562, 1611], 'brief': [565, 981], 'aphasia': [569, 749], 'MRI.': [573], '(SWI)': [576, 770], '(A–D,': [578, 779], 'red': [579, 780], 'arrows': [580], 'circles': [582, 793], 'dotted': [584, 795], 'lines)': [585], 'regions': [592, 778], 'frontal': [595], 'lobes.': [598], '(FLAIR)': [602], '(E)': [604], 'small': [608, 847, 1283], 'bilateral': [609, 687], '(F)': [619], 'centrum-semiovale.Two': [626], 'months': [627, 1607], 'later': [628, 1608], 'sudden-onset': [633, 1025], 'right-sided': [635], 'hemiparesis,': [636], 'sensory': [638], 'deficits.': [639], 'examination': [641], 'Institutes': [645, 832], 'Health': [647, 834], 'Stroke': [648, 835], 'Scale': [649, 836], 'Score': [650], '7.': [652], 'Brain': [653, 665, 679], 'lobar': [658, 683, 711, 881, 896, 1326, 1613], 'ICH': [659, 684, 897, 908, 1327, 1373, 1394, 1405, 1639], 'frontotemporal': [661], 'perifocal': [663], 'edema.': [664], 'tomography–angiography': [667], 'did': [668], 'find': [670], 'aneurysms,': [672], 'vascular': [673, 1306, 1529], 'malformations,': [674], 'or': [675, 926, 1028, 1054, 1131, 1157, 1166, 1231, 1508, 1520, 1553], 'other': [676, 1259, 1528, 1758], 'abnormal': [677], 'findings.': [678], 'areas': [688, 1290], 'cSS': [690, 697, 925, 937, 951, 969, 1158, 1364, 1430], 'without': [691, 872, 1359], 'any': [692, 1372], 'microbleeds': [694], '(Figure': [695], '2).': [696], 'identified': [698], 'post': [699], 'hoc': [700], 'previous': [702, 745], 'identical': [705], 'location': [708], 'current': [710], 'ICH.': [712, 1614], 'probable': [718], 'amyloid': [720, 920, 1818, 1863, 1886, 1924, 1959, 2004, 2034, 2075, 2381], 'angiopathy': [721, 2076], '(CAA)': [722], 'according': [723, 1247], 'revised': [726, 1250], 'Boston-Criteria': [727, 956], 'v2.01': [728], 'ApoE': [730], 'genotype': [731, 1421], 'ε2/ε3': [733], 'alleles.': [734], 'After': [735], 'reevaluation': [736], "patient's": [739], 'history,': [740], 'we': [741, 1573], 'hypothesized': [742], 'that': [743], 'neurological': [754, 2071], '(TFNE)': [756], 'underlying': [759, 889, 1261, 1516], 'cSS.Download': [760], '2.': [763], 'Follow-up': [764], 'imaging.': [767], 'arrows)': [781], 'temporoparietal': [789], 'lobe.': [790], 'E–F,': [791], 'Red': [792], 'lines.Antiplatelet': [796], 'withdrawn': [799], 'conservatively': [805], 'osmotic': [807], 'tight': [810], 'control': [811], 'blood': [814, 1468], 'pressure.': [815], 'He': [816], 'gradual': [818], 'radiological': [821, 961], 'improvement.': [822], 'Ten': [823], 'days': [824], 'later,': [825], 'he': [826], 'discharged': [828], 'an': [830, 959, 1515, 2170, 2214], 'score': [837], '4': [839, 1402], 'rehabilitation': [842], 'facility.DiscussionSporadic': [843], 'vessel': [848], 'disease,': [849], 'affecting': [850], 'cortical/leptomeningeal': [851], 'arterioles': [852], 'characterized': [855, 986, 1201], 'pathologically': [856], 'deposition': [858, 1065, 1082], 'amyloid-Aβ': [860], 'within': [861, 1070, 1208], 'cerebrovascular': [863], 'wall.2': [864], 'It': [865], 'disease': [868], 'elderly': [871], 'sex': [873], 'predominance': [874], 'spectrum': [878], 'includes': [879], 'spontaneous': [880, 895, 1325], 'ICH,': [882, 1353], 'cognitive': [883], 'decline,': [884], 'CAA-related': [886, 907, 1191, 1257, 1297, 1313, 1578, 1636, 1662], 'TFNEs.2': [887], 'cause': [890, 1177], 'about': [892], '74%': [893], 'CAA.': [899], 'Even': [900], 'absence': [903], 'oral': [905], 'anticoagulation,': [906], 'has': [909], 'high': [911, 1458, 1674], 'recurrence': [912], '(≈10%': [914], 'per': [915], 'year).CAA-related': [916], 'TFNEs,': [917, 1203], 'also': [918, 1036, 1136, 1244, 1423], 'called': [919], 'spells,': [921], 'attributed': [923, 1059], 'convexity': [927, 1999], 'subarachnoid': [928, 1073, 1118, 2000], '(cSAH),': [930], 'manifestation': [935], 'phase': [941, 1465], 'possibly': [943], 'originates': [944], 'CAA-affected': [946], 'leptomeningeal': [947, 1091], 'vessels.3': [948], 'In': [949, 1500, 1650, 2279], '2010,': [950], 'included': [953], 'modified': [955], 'v1.5.': [957], 'emerging': [960], 'marker,4': [962], 'calculated': [971], '≈50%': [974], 'CAA.TFNEs': [978], 'duration': [982], '(<30': [983], 'minutes)': [984], 'symptoms,': [993], 'progression': [996, 1956], 'mimicking': [997], 'migratory': [999], 'spread.3': [1000], 'More': [1001, 1331], 'predominantly': [1009], 'positive': [1010], 'including': [1012, 1159, 1263, 1551], 'aura-like': [1013], 'paresthesias,': [1015], 'limb': [1016, 1026], 'jerking,': [1017], 'visual': [1019], 'paresthesias.': [1020], 'Negative': [1021], 'such': [1023], 'weakness': [1027], 'resemble': [1031], 'attacks': [1034, 1507], 'common.3': [1037], 'majority': [1039], 'these': [1041], 'multiple,': [1044], '(≥2),': [1047], 'over': [1048, 1183], 'course': [1050], 'weeks,': [1053], 'years.3CAA-related': [1055], 'mostly': [1058], 'cSS,': [1061, 1360, 1382, 1439], 'represents': [1063], 'chronic': [1067], 'blood-breakdown': [1068], 'products': [1069], 'supratentorial,': [1072], 'space': [1074, 1119], 'layers.3': [1080], 'responsible': [1084], 'curvilinear': [1086], 'hypointense': [1087], 'convexities,': [1095, 1122], 'detected': [1096, 1107, 1293], 'blood-sensitive': [1098, 1139], 'sequences.': [1100], 'Another': [1101], 'feature': [1104], 'cSAH,': [1106, 1467], 'on': [1108, 1194, 1491, 2259], 'limited': [1115, 1557, 2238], 'extending': [1124], 'into': [1125, 1275], 'parenchyma,': [1127], 'sylvian': [1128], 'fissures,': [1129], 'ventricles,': [1130], 'basal': [1132], 'cisterns.': [1133], 'cSAH': [1134, 1156, 1179, 1339, 1347], 'seen': [1137, 1308], 'blooming': [1144], 'same': [1147], 'region.5': [1148], 'There': [1149], 'wide': [1152], 'reversible': [1160], 'vasoconstriction': [1162], 'syndrome,': [1163], 'vein': [1165], 'dural': [1167], 'sinus': [1168], 'thrombosis,': [1169], 'aneurysm': [1170], 'rupture,': [1171], 'etc.': [1172], 'However,': [1173], '60': [1184], 'years': [1185, 1241], 'overwhelmingly': [1187], 'CAA.6The': [1188], 'relies': [1193], 'identification': [1195], 'compatible': [1198], 'syndrome': [1200], 'often': [1204, 1287], 'unilateral,': [1205], 'usually': [1206], 'resolving': [1207], '30': [1209], 'minutes.3': [1210], 'Main': [1211], 'migratory-like': [1216], 'spread': [1217], 'body': [1220], 'part': [1221], 'another': [1223], 'well': [1225], 'stereotypic,': [1227], 'recurrent': [1228, 1329, 1346], 'episodes.': [1229], 'Neuropathologic': [1230], 'evidence': [1233], 'older': [1238], '50': [1240], 'old': [1242], 'fulfilled': [1246], 'Boston-criteria': [1251], 'v2.0.1': [1252], 'Not': [1253], 'all': [1254, 1475, 1626], 'causes,': [1262], 'migraine': [1264], 'aura,': [1266], 'seizures,': [1268], 'structural': [1269], 'lesions,': [1270], 'etc': [1271], 'taken': [1274], 'account.': [1276], 'Neurologists': [1277], 'able': [1280], 'differentiate': [1282], 'diffusion-weighted': [1284, 1301], 'close': [1288], 'larger': [1300], 'specific': [1305], 'territories,': [1307], 'infarcts.3,5Prognosis': [1311], 'strongly': [1316], 'future': [1323, 1345, 1352, 1455], 'symptomatic': [1324], 'cSAH.': [1330], 'specifically,': [1332], 'who': [1336, 1409], 'suffered': [1337], '11%': [1342], '13%': [1349], 'respectively.6': [1354], 'Comparing': [1355], 'presence': [1362, 1435, 1443], 'doubles': [1368], 'future,': [1376], 'cases': [1379, 1501], 'disseminated': [1381], '4×': [1386], 'higher.7': [1387], 'Moreover,': [1388, 1548], 'study': [1391, 1682, 1731], 'doubled': [1393], 'incidence': [1395, 1406], 'motor': [1399], 'times': [1403], 'received': [1410], 'agents.8': [1412], 'Despite': [1413], 'unknown': [1415], 'pathophysiological': [1416], 'mechanism,': [1417], 'APOE': [1419, 1445, 2119], 'ε2/+': [1420, 1446], 'bleeding': [1432, 1459, 1675, 2030], 'risk.9': [1433], 'Consequently,': [1434], 'extent': [1437], 'therapy,': [1441], 'alleles': [1447], 'important': [1450, 1698, 1723, 1743], 'prognostic': [1451], 'factors': [1453], 'ICH.Due': [1456], 'risk,': [1460], 'especially': [1461], 'pressure': [1469], 'tightly': [1472], 'controlled': [1473, 1538], 'antithrombotic/anticoagulant': [1476], 'medications': [1477], 'at': [1482], 'least': [1483], '24': [1484], '48': [1486], 'hours.10': [1487], 'Later': [1488], 'dependent': [1490], 'indication,': [1493], 'their': [1494, 1560], 'administration': [1495, 1588], 'reevaluated': [1498], 'accordingly.': [1499], 'where': [1504], 'strokes': [1510], 'cannot': [1511], 'mechanism': [1517], 'coexisting': [1524], 'atrial': [1525, 1544], 'fibrillation': [1526], 'factors,': [1531], 'hypertension,': [1532], 'diabetes,': [1533], 'option': [1541], 'appendage': [1545], 'occlusion': [1546], 'discussed.3': [1547], 'antiepileptic': [1549], 'medications,': [1550], 'levetiracetam': [1552], 'lacosamide,': [1554], 'despite': [1555], 'data': [1558, 1715, 2009], 'regarding': [1559], 'effectiveness,': [1561], 'may': [1562], 'useful': [1564], 'persistent': [1568], 'attacks.3In': [1569], 'case': [1571, 1616, 1653], 'report,': [1572], 'present': [1574], 'TFNE,': [1579], 'attack,': [1585], 'leading': [1586], 'antiplatelet': [1590, 2156], 'erroneously': [1602], 'symptomatic.': [1605], 'Two': [1606], 'illustrates': [1617], 'devastating': [1620], 'consequences': [1621], 'evaluating': [1625], 'available': [1627], 'findings': [1629], 'administrating': [1631], 'antithrombotics': [1632], 'TFNEs;': [1637], 'clearly': [1642], 'cSS/cSAH.': [1649], 'conclusion,': [1651], 'highlights': [1654], 'importance': [1656], 'comprehensive': [1659], 'understanding': [1660], 'continuous': [1665], 'vigilance': [1666], 'detect': [1668], 'them': [1669], 'avoid': [1671], 'therapies': [1672], 'risk.Article': [1676], 'InformationAcknowledgmentsDr': [1677], 'contributed': [1679, 1710, 1728], 'concept': [1683], 'design,': [1685], 'acquisition': [1686, 1713], 'data,': [1688], 'interpretation,': [1689, 1735], 'writing,': [1690], 'critical': [1692, 1717, 1737], 'revision': [1693, 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[1801], 'Barbato': [1803], 'C,': [1804, 1840, 1850, 1880, 2146], 'Bonneville': [1805], 'F,': [1806, 1980], 'Brandner': [1807], 'S,': [1808, 1988, 2102, 2108, 2140, 2319, 2321], 'et': [1809, 1853, 1951, 1989, 2117], 'al.': [1810, 1854, 1952, 1990, 2118], 'Boston': [1812], 'criteria': [1813], '2.0': [1815], 'angiopathy:': [1819, 1864, 1960, 2005, 2035], 'multicentre,': [1821], 'retrospective,': [1822], 'MRI-neuropathology': [1823], 'diagnostic': [1824], 'accuracy': [1825], 'study.Lancet': [1826], 'Neurol.': [1827, 2012, 2091], '2022;': [1828, 1870, 2013, 2092], '21:714–725.': [1829], 'doi:': [1830, 1872, 1894, 1928, 1966, 2015, 2040, 2094, 2132, 2162], '10.1016/S1474-4422(22)00208-3CrossrefGoogle': [1831], 'Scholar2.': [1832], 'Malhotra': [1833], 'K,': [1834, 2104, 2303, 2313, 2329], 'Katsanos': [1837], 'AH,': [1838], 'Zompola': [1839, 2145], 'Shoamanesh': [1841, 2105], 'Boviatsis': [1843], 'E,': [1844, 2054, 2066, 2307, 2317, 2325], 'GP,': [1846, 2142], 'Spilioti': [1847], 'Cordonnier': [1849], 'Werring': [1851, 1881], 'DJ,': [1852, 1882], 'Prevalence': [1855, 1916], 'markers': [1860], 'systematic': [1866, 2087], 'review': [1867, 2088], 'meta-analysis.Stroke.': [1869], '53:1944–1953.': [1871], '10.1161/STROKEAHA.121.035836LinkGoogle': [1873], 'Scholar3.': [1874], 'Smith': [1875], 'EE,': [1876], 'Ayata': [1879], 'Greenberg': [1883, 1914, 1949, 2022], 'SM.': [1884, 1915], 'angiopathy-related': [1887], 'episodes.Neurology.': [1891], '2021;': [1892, 2160], '97:231–238.': [1893], '10.1212/WNL.0000000000012234CrossrefGoogle': [1895], 'Scholar4.': [1896], 'Linn': [1897], 'J,': [1898, 1904, 1946, 2327], 'Halpin': [1899], 'Demaerel': [1901], 'P,': [1902, 1934], 'Ruhland': [1903], 'Giese': [1905], 'AD,': [1906, 1942], 'Dichgans': [1907], 'van': [1909], 'Buchem': [1910], 'MA,': [1911], 'Bruckmann': [1912], 'H,': [1913], 'angiopathy.Neurology.': [1925], '2010;': [1926], '74:1346–1350.': [1927], '10.1212/WNL.0b013e3181dad605CrossrefMedlineGoogle': [1929], 'Scholar5.': [1930], 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