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mm The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK; nn Houston Methodist Cancer Center, Houston, TX, USA; oo Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA; pp Department of Surgery, University of Port Harcourt Teaching Hospital, Alakahia, Port Harcourt, Nigeria; qq University of California Davis School of Medicine, Sacramento, CA, USA; rr IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; ss University of California San Francisco, San Francisco, CA, USA; tt Department of Radiation-Oncology, Ghent University Hospital, Ghent, Belgium; uu Department of Urology, Ospedale Regionale di Lugano, Civico USI -Università della Svizzera Italiana, Lugano, Switzerland; vv Department of Surgery, Prostate Cancer Research Program, Monash University, Melbourne, Australia; ww Department of Anatomy & Developmental Biology, Faculty of Nursing, Medicine & Health Sciences, Monash University, Melbourne, Australia; xx Department of Medicine, Duke Cancer Institute, Duke University, Durham, NC, USA; 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