Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4308179880', 'doi': 'https://doi.org/10.1007/s11030-022-10555-w', 'title': 'Can machine learning ‘transform’ peptides/peptidomimetics into small molecules? A case study with ghrelin receptor ligands', 'display_name': 'Can machine learning ‘transform’ peptides/peptidomimetics into small molecules? A case study with ghrelin receptor ligands', 'publication_year': 2022, 'publication_date': '2022-11-04', 'ids': {'openalex': 'https://openalex.org/W4308179880', 'doi': 'https://doi.org/10.1007/s11030-022-10555-w', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36331785'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11030-022-10555-w', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S105791650', 'display_name': 'Molecular Diversity', 'issn_l': '1381-1991', 'issn': ['1381-1991', '1573-501X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100428669', 'display_name': 'Wenjie Liu', 'orcid': 'https://orcid.org/0000-0002-1133-5039'}, 'institutions': [{'id': 'https://openalex.org/I4210100115', 'display_name': 'Thunder Bay Regional Research Institute', 'ror': 'https://ror.org/013kbs677', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210100115']}, {'id': 'https://openalex.org/I72541430', 'display_name': 'Lakehead University', 'ror': 'https://ror.org/023p7mg82', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I72541430']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Wenjie Liu', 'raw_affiliation_strings': ['Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada', 'institution_ids': ['https://openalex.org/I4210100115', 'https://openalex.org/I72541430']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044781499', 'display_name': 'Austin M. Hopkins', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100115', 'display_name': 'Thunder Bay Regional Research Institute', 'ror': 'https://ror.org/013kbs677', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210100115']}, {'id': 'https://openalex.org/I72541430', 'display_name': 'Lakehead University', 'ror': 'https://ror.org/023p7mg82', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I72541430']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Austin M. Hopkins', 'raw_affiliation_strings': ['Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada', 'institution_ids': ['https://openalex.org/I4210100115', 'https://openalex.org/I72541430']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026270465', 'display_name': 'Peizhi Yan', 'orcid': 'https://orcid.org/0000-0002-6093-2964'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Peizhi Yan', 'raw_affiliation_strings': ['Department of Electrical and Computer Engineering, The University of British Columbia, Vancouver, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Electrical and Computer Engineering, The University of British Columbia, Vancouver, Canada', 'institution_ids': ['https://openalex.org/I141945490']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049374513', 'display_name': 'Shan Du', 'orcid': 'https://orcid.org/0000-0002-2281-5150'}, 'institutions': [{'id': 'https://openalex.org/I822440', 'display_name': 'Okanagan University College', 'ror': 'https://ror.org/02mxmh518', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I822440']}, {'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Shan Du', 'raw_affiliation_strings': ['Department of Computer Science, Mathematics, Physics and Statistics, The University of British Columbia, Okanagan, Kelowna, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Computer Science, Mathematics, Physics and Statistics, The University of British Columbia, Okanagan, Kelowna, Canada', 'institution_ids': ['https://openalex.org/I822440', 'https://openalex.org/I141945490']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067578877', 'display_name': 'Leonard G. Luyt', 'orcid': 'https://orcid.org/0000-0002-0941-4731'}, 'institutions': [{'id': 'https://openalex.org/I131944076', 'display_name': 'Lawson Health Research Institute', 'ror': 'https://ror.org/051gsh239', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I131944076']}, {'id': 'https://openalex.org/I125749732', 'display_name': 'Western University', 'ror': 'https://ror.org/02grkyz14', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I125749732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Leonard G. Luyt', 'raw_affiliation_strings': ['Department of Chemistry, University of Western Ontario, London, Canada', 'London Regional Cancer Program, Lawson Health Research Institute, London, Canada'], 'affiliations': [{'raw_affiliation_string': 'London Regional Cancer Program, Lawson Health Research Institute, London, Canada', 'institution_ids': ['https://openalex.org/I131944076']}, {'raw_affiliation_string': 'Department of Chemistry, University of Western Ontario, London, Canada', 'institution_ids': ['https://openalex.org/I125749732']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033510515', 'display_name': 'Yifeng Li', 'orcid': 'https://orcid.org/0000-0002-4873-6928'}, 'institutions': [{'id': 'https://openalex.org/I186803428', 'display_name': 'Brock University', 'ror': 'https://ror.org/056am2717', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I186803428']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Yifeng Li', 'raw_affiliation_strings': ['Department of Computer Science, Brock University, Saint Catharines, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Computer Science, Brock University, Saint Catharines, Canada', 'institution_ids': ['https://openalex.org/I186803428']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024696793', 'display_name': 'Jinqiang Hou', 'orcid': 'https://orcid.org/0000-0003-4467-638X'}, 'institutions': [{'id': 'https://openalex.org/I4210100115', 'display_name': 'Thunder Bay Regional Research Institute', 'ror': 'https://ror.org/013kbs677', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210100115']}, {'id': 'https://openalex.org/I72541430', 'display_name': 'Lakehead University', 'ror': 'https://ror.org/023p7mg82', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I72541430']}], 'countries': ['CA'], 'is_corresponding': True, 'raw_author_name': 'Jinqiang Hou', 'raw_affiliation_strings': ['Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Lakehead University and Thunder Bay Regional Health Research Institute, Thunder Bay, Canada', 'institution_ids': ['https://openalex.org/I4210100115', 'https://openalex.org/I72541430']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5024696793'], 'corresponding_institution_ids': ['https://openalex.org/I4210100115', 'https://openalex.org/I72541430'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.236, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.457239, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 62, 'max': 72}, 'biblio': {'volume': '27', 'issue': '5', 'first_page': '2239', 'last_page': '2255'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10211', 'display_name': 'Computational Methods in Drug Discovery', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10211', 'display_name': 'Computational Methods in Drug Discovery', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12254', 'display_name': 'Prediction of Protein Subcellular Localization', 'score': 0.9949, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10911', 'display_name': 'Peptide Synthesis and Drug Discovery', 'score': 0.9877, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/peptidomimetic', 'display_name': 'Peptidomimetic', 'score': 0.9358382}, {'id': 'https://openalex.org/keywords/molecular-docking', 'display_name': 'Molecular Docking', 'score': 0.506194}], 'concepts': [{'id': 'https://openalex.org/C124790011', 'wikidata': 'https://www.wikidata.org/wiki/Q2069797', 'display_name': 'Peptidomimetic', 'level': 3, 'score': 0.9358382}, {'id': 'https://openalex.org/C161624437', 'wikidata': 'https://www.wikidata.org/wiki/Q1988322', 'display_name': 'Small molecule', 'level': 2, 'score': 0.74770176}, {'id': 'https://openalex.org/C2779281246', 'wikidata': 'https://www.wikidata.org/wiki/Q172847', 'display_name': 'Peptide', 'level': 2, 'score': 0.61042714}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5011637}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.4683418}, {'id': 'https://openalex.org/C74187038', 'wikidata': 'https://www.wikidata.org/wiki/Q1418791', 'display_name': 'Drug discovery', 'level': 2, 'score': 0.4535592}, {'id': 'https://openalex.org/C32909587', 'wikidata': 'https://www.wikidata.org/wiki/Q11369', 'display_name': 'Molecule', 'level': 2, 'score': 0.42931253}, {'id': 'https://openalex.org/C21951064', 'wikidata': 'https://www.wikidata.org/wiki/Q899212', 'display_name': 'Combinatorial chemistry', 'level': 1, 'score': 0.3929468}, {'id': 'https://openalex.org/C154945302', 'wikidata': 'https://www.wikidata.org/wiki/Q11660', 'display_name': 'Artificial intelligence', 'level': 1, 'score': 0.33481008}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.30500573}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25643212}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.19189465}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D057786', 'descriptor_name': 'Peptidomimetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069550', 'descriptor_name': 'Machine Learning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D057786', 'descriptor_name': 'Peptidomimetics', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D054440', 'descriptor_name': 'Receptors, Ghrelin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060388', 'descriptor_name': 'Support Vector Machine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11030-022-10555-w', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S105791650', 'display_name': 'Molecular Diversity', 'issn_l': '1381-1991', 'issn': ['1381-1991', '1573-501X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36331785', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'score': 0.52, 'display_name': 'Zero hunger'}], 'grants': [{'funder': 'https://openalex.org/F4320334593', 'funder_display_name': 'Natural Sciences and Engineering Research Council of Canada', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1988037271', 'https://openalex.org/W2002886956', 'https://openalex.org/W2011301426', 'https://openalex.org/W2016525263', 'https://openalex.org/W2044573804', 'https://openalex.org/W2044834685', 'https://openalex.org/W2050864715', 'https://openalex.org/W2101517369', 'https://openalex.org/W2155478691', 'https://openalex.org/W2159675211', 'https://openalex.org/W2159887157', 'https://openalex.org/W2336040088', 'https://openalex.org/W2504854013', 'https://openalex.org/W2506776793', 'https://openalex.org/W2724823461', 'https://openalex.org/W2784122696', 'https://openalex.org/W2790719843', 'https://openalex.org/W2791796577', 'https://openalex.org/W2804885211', 'https://openalex.org/W2887346809', 'https://openalex.org/W2894943857', 'https://openalex.org/W2900813162', 'https://openalex.org/W2903703296', 'https://openalex.org/W2911964244', 'https://openalex.org/W2937307539', 'https://openalex.org/W2959938226', 'https://openalex.org/W2962862931', 'https://openalex.org/W2964113829', 'https://openalex.org/W2970198780', 'https://openalex.org/W2971690404', 'https://openalex.org/W2973049920', 'https://openalex.org/W2998247571', 'https://openalex.org/W3001059052', 'https://openalex.org/W3005694952', 'https://openalex.org/W3012202150', 'https://openalex.org/W3024596683', 'https://openalex.org/W3065797019', 'https://openalex.org/W3109675364', 'https://openalex.org/W3122442460', 'https://openalex.org/W3137812680', 'https://openalex.org/W3172978511', 'https://openalex.org/W3194368700', 'https://openalex.org/W3196831580', 'https://openalex.org/W3211668464', 'https://openalex.org/W3216788064', 'https://openalex.org/W4211061743', 'https://openalex.org/W4212969303', 'https://openalex.org/W4230674625', 'https://openalex.org/W4247128285'], 'related_works': ['https://openalex.org/W3044962842', 'https://openalex.org/W3031857447', 'https://openalex.org/W2952841437', 'https://openalex.org/W2921492615', 'https://openalex.org/W2894156068', 'https://openalex.org/W2292990827', 'https://openalex.org/W2142350160', 'https://openalex.org/W2038252445', 'https://openalex.org/W2036201821', 'https://openalex.org/W1503419137'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4308179880', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}], 'updated_date': '2024-08-28T01:28:25.180769', 'created_date': '2022-11-08'}