Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4308123709', 'doi': 'https://doi.org/10.3390/ijms232113299', 'title': 'Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs', 'display_name': 'Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs', 'publication_year': 2022, 'publication_date': '2022-10-31', 'ids': {'openalex': 'https://openalex.org/W4308123709', 'doi': 'https://doi.org/10.3390/ijms232113299', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36362086'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms232113299', 'pdf_url': 'https://www.mdpi.com/1422-0067/23/21/13299/pdf?version=1667813196', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1422-0067/23/21/13299/pdf?version=1667813196', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5054567757', 'display_name': 'Qing Jiang', 'orcid': 'https://orcid.org/0000-0003-1875-6263'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}, {'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}], 'countries': ['CN', 'JP'], 'is_corresponding': False, 'raw_author_name': 'Qing Jiang', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'Institute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}, {'raw_affiliation_string': 'Institute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China', 'institution_ids': ['https://openalex.org/I3923682']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100804856', 'display_name': 'Xin Qin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}, {'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}], 'countries': ['CN', 'JP'], 'is_corresponding': False, 'raw_author_name': 'Xin Qin', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'Institute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}, {'raw_affiliation_string': 'Institute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China', 'institution_ids': ['https://openalex.org/I3923682']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040113122', 'display_name': 'Kenichi Nagano', 'orcid': 'https://orcid.org/0000-0003-3145-4841'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kenichi Nagano', 'raw_affiliation_strings': ['Department of Oral Pathology and Bone Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Oral Pathology and Bone Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074636884', 'display_name': 'Hisato Komori', 'orcid': 'https://orcid.org/0000-0001-6802-949X'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hisato Komori', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037690982', 'display_name': 'Yuki Matsuo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuki Matsuo', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080779198', 'display_name': 'Ichiro Taniuchi', 'orcid': 'https://orcid.org/0000-0002-9853-9068'}, 'institutions': [{'id': 'https://openalex.org/I4210150921', 'display_name': 'RIKEN Center for Integrative Medical Sciences', 'ror': 'https://ror.org/04mb6s476', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210110652', 'https://openalex.org/I4210150921']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ichiro Taniuchi', 'raw_affiliation_strings': ['Laboratory for Transcriptional Regulation, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Transcriptional Regulation, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan', 'institution_ids': ['https://openalex.org/I4210150921']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027197244', 'display_name': 'Kosei Ito', 'orcid': 'https://orcid.org/0000-0002-8416-2466'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kosei Ito', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010742020', 'display_name': 'Toshihisa Komori', 'orcid': 'https://orcid.org/0000-0002-0284-5723'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Toshihisa Komori', 'raw_affiliation_strings': ['Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5010742020'], 'corresponding_institution_ids': ['https://openalex.org/I43777268'], 'apc_list': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 0.466, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.615055, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 78, 'max': 81}, 'biblio': {'volume': '23', 'issue': '21', 'first_page': '13299', 'last_page': '13299'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11219', 'display_name': 'Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11219', 'display_name': 'Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11221', 'display_name': 'Bisphosphonates in Cancer Treatment and Bone Health', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10658', 'display_name': 'Epidemiology and Treatment of Bone Fractures', 'score': 0.9766, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/runx2', 'display_name': 'RUNX2', 'score': 0.88316965}, {'id': 'https://openalex.org/keywords/cleidocranial-dysplasia', 'display_name': 'Cleidocranial Dysplasia', 'score': 0.8369527}, {'id': 'https://openalex.org/keywords/calvaria', 'display_name': 'Calvaria', 'score': 0.833294}, {'id': 'https://openalex.org/keywords/regulation-of-bone-homeostasis', 'display_name': 'Regulation of Bone Homeostasis', 'score': 0.492224}], 'concepts': [{'id': 'https://openalex.org/C2776363554', 'wikidata': 'https://www.wikidata.org/wiki/Q14907085', 'display_name': 'RUNX2', 'level': 4, 'score': 0.88316965}, {'id': 'https://openalex.org/C2908903051', 'wikidata': 'https://www.wikidata.org/wiki/Q781618', 'display_name': 'Cleidocranial Dysplasia', 'level': 3, 'score': 0.8369527}, {'id': 'https://openalex.org/C2779918246', 'wikidata': 'https://www.wikidata.org/wiki/Q613203', 'display_name': 'Calvaria', 'level': 3, 'score': 0.833294}, {'id': 'https://openalex.org/C673006', 'wikidata': 'https://www.wikidata.org/wiki/Q4941581', 'display_name': 'Bone resorption', 'level': 2, 'score': 0.45154023}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.44356537}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36844766}, {'id': 'https://openalex.org/C2778260815', 'wikidata': 'https://www.wikidata.org/wiki/Q917177', 'display_name': 'Osteoblast', 'level': 3, 'score': 0.33250046}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.26744294}, {'id': 'https://openalex.org/C2780610479', 'wikidata': 'https://www.wikidata.org/wiki/Q7644068', 'display_name': 'Supernumerary', 'level': 2, 'score': 0.094451964}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.085562885}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D050659', 'descriptor_name': 'Core Binding Factor Alpha 1 Subunit', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010006', 'descriptor_name': 'Osteoblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050659', 'descriptor_name': 'Core Binding Factor Alpha 1 Subunit', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D050659', 'descriptor_name': 'Core Binding Factor Alpha 1 Subunit', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050657', 'descriptor_name': 'Core Binding Factor alpha Subunits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050657', 'descriptor_name': 'Core Binding Factor alpha Subunits', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010006', 'descriptor_name': 'Osteoblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010012', 'descriptor_name': 'Osteogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010012', 'descriptor_name': 'Osteogenesis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012272', 'descriptor_name': 'Ribs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012272', 'descriptor_name': 'Ribs', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012886', 'descriptor_name': 'Skull', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012886', 'descriptor_name': 'Skull', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013131', 'descriptor_name': 'Spine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013131', 'descriptor_name': 'Spine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms232113299', 'pdf_url': 'https://www.mdpi.com/1422-0067/23/21/13299/pdf?version=1667813196', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/874196a2a73043b1aaf80694268bfea4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657020', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36362086', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms232113299', 'pdf_url': 'https://www.mdpi.com/1422-0067/23/21/13299/pdf?version=1667813196', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1623821869', 'https://openalex.org/W1991766825', 'https://openalex.org/W1997812904', 'https://openalex.org/W2003617876', 'https://openalex.org/W2010254035', 'https://openalex.org/W2013580179', 'https://openalex.org/W2013714561', 'https://openalex.org/W2023167270', 'https://openalex.org/W2025046506', 'https://openalex.org/W2036287488', 'https://openalex.org/W2036369014', 'https://openalex.org/W2044354916', 'https://openalex.org/W2085033687', 'https://openalex.org/W2086083531', 'https://openalex.org/W2095906628', 'https://openalex.org/W2096425957', 'https://openalex.org/W2098326006', 'https://openalex.org/W2102059629', 'https://openalex.org/W2110571520', 'https://openalex.org/W2112274246', 'https://openalex.org/W2122433264', 'https://openalex.org/W2130671879', 'https://openalex.org/W2131702860', 'https://openalex.org/W2133010718', 'https://openalex.org/W2151263644', 'https://openalex.org/W2152541409', 'https://openalex.org/W2161985793', 'https://openalex.org/W2167775400', 'https://openalex.org/W2171002939', 'https://openalex.org/W2317965794', 'https://openalex.org/W2398967024', 'https://openalex.org/W2789054899', 'https://openalex.org/W2901669407', 'https://openalex.org/W2991125297', 'https://openalex.org/W3036373820', 'https://openalex.org/W3108216847', 'https://openalex.org/W3121667689', 'https://openalex.org/W3170350942', 'https://openalex.org/W4281256926'], 'related_works': ['https://openalex.org/W4388861022', 'https://openalex.org/W3094260794', 'https://openalex.org/W3048800660', 'https://openalex.org/W2548535584', 'https://openalex.org/W2359911484', 'https://openalex.org/W2321503130', 'https://openalex.org/W2217100198', 'https://openalex.org/W2160248324', 'https://openalex.org/W2019480635', 'https://openalex.org/W1988944924'], 'abstract_inverted_index': {'RUNX': [0, 42], 'proteins,': [1], 'such': [2], 'as': [3], 'RUNX2,': [4, 156], 'regulate': [5], 'the': [6, 36, 93, 107, 151, 157, 165, 182], 'proliferation': [7], 'and': [8, 12, 38, 49, 62, 71, 109, 155, 162, 167, 177, 189], 'differentiation': [9], 'of': [10, 15, 24, 41, 153, 159, 170, 175], 'chondrocytes': [11], 'osteoblasts.': [13, 171], 'Haploinsufficiency': [14], 'RUNX2': [16, 178], 'causes': [17], 'cleidocranial': [18], 'dysplasia,': [19], 'but': [20, 85, 96, 126, 138], 'a': [21, 52], 'detailed': [22], 'analysis': [23], 'Runx2+/-': [25, 76, 83, 115, 129, 141], 'mice': [26, 66, 84, 125, 137], 'has': [27, 46], 'not': [28, 97, 127, 139], 'been': [29], 'reported.': [30], 'Furthermore,': [31], 'CBFB': [32, 45, 154, 176], 'is': [33], 'required': [34, 180], 'for': [35, 185], 'stability': [37], 'DNA': [39], 'binding': [40], 'family': [43], 'proteins.': [44], 'two': [47], 'isoforms,': [48], 'CBFB2': [50], 'plays': [51], 'major': [53], 'role': [54], 'in': [55, 64, 75, 82, 88, 102, 114, 120, 123, 128, 135, 140, 150], 'skeletal': [56], 'development.': [57], 'The': [58, 117], 'calvaria,': [59], 'femurs,': [60, 92], 'vertebrae': [61, 121], 'ribs': [63], 'Cbfb2-/-': [65, 89, 103, 124, 136], 'were': [67, 112, 145, 179], 'analyzed': [68], 'after': [69], 'birth,': [70], 'compared': [72], 'with': [73], 'those': [74], 'mice.': [77, 90, 116, 130, 142], 'Calvarial': [78], 'development': [79, 132, 188], 'was': [80, 100, 133], 'impaired': [81, 134], 'mildly': [86], 'delayed': [87], 'In': [91], 'cortical': [94, 110], 'bone': [95, 99, 111, 119, 160, 183, 187], 'trabecular': [98, 108, 118], 'reduced': [101, 113], 'mice,': [104], 'whereas': [105], 'both': [106], 'increased': [122], 'Rib': [131], 'These': [143], 'differences': [144, 149], 'likely': [146], 'caused': [147], 'by': [148], 'indispensability': [152], 'balance': [158], 'formation': [161], 'resorption,': [163], 'or': [164], 'number': [166], 'maturation': [168], 'stage': [169], 'Thus,': [172], 'different': [173], 'amounts': [174], 'among': [181], 'tissues': [184], 'proper': [186], 'maintenance.': [190]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4308123709', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}], 'updated_date': '2024-09-08T21:55:29.597023', 'created_date': '2022-11-08'}