Publication Information

{'id': 'https://openalex.org/W4304889421', 'doi': 'https://doi.org/10.1101/2022.10.12.511867', 'title': 'FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors', 'display_name': 'FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors', 'publication_year': 2022, 'publication_date': '2022-10-12', 'ids': {'openalex': 'https://openalex.org/W4304889421', 'doi': 'https://doi.org/10.1101/2022.10.12.511867'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.10.12.511867', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/10/12/2022.10.12.511867.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'type': 'preprint', 'type_crossref': 'posted-content', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/10/12/2022.10.12.511867.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101540144', 'display_name': 'Giang Nguyen', 'orcid': 'https://orcid.org/0000-0002-3136-0485'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}, {'id': 'https://openalex.org/I123565023', 'display_name': 'Vietnam National University Ho Chi Minh City', 'ror': 'https://ror.org/00waaqh38', 'country_code': 'VN', 'type': 'education', 'lineage': ['https://openalex.org/I123565023']}], 'countries': ['AU', 'VN'], 'is_corresponding': False, 'raw_author_name': 'Giang Thanh Nguyen-Dien', 'raw_affiliation_strings': ['Department of Biotechnology, School of Biotechnology, Viet Nam National University-International University, Ho Chi Minh City, Vietnam', 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}, {'raw_affiliation_string': 'Department of Biotechnology, School of Biotechnology, Viet Nam National University-International University, Ho Chi Minh City, Vietnam', 'institution_ids': ['https://openalex.org/I123565023']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064926521', 'display_name': 'Keri‐Lyn Kozul', 'orcid': 'https://orcid.org/0000-0001-5162-4807'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Keri-Lyn Kozul', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050688071', 'display_name': 'Yi Cui', 'orcid': 'https://orcid.org/0000-0002-8787-9163'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Yi Cui', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010173449', 'display_name': 'Brendan Townsend', 'orcid': 'https://orcid.org/0000-0003-2839-8981'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Brendan Townsend', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063424219', 'display_name': 'Prajakta Gosavi', 'orcid': 'https://orcid.org/0000-0002-0960-8237'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Prajakta Gosavi Kulkarni', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000747636', 'display_name': 'Soo Siang Ooi', 'orcid': 'https://orcid.org/0000-0002-0188-7198'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Soo Siang Ooi', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050123515', 'display_name': 'Antonio Marzio', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Antonio Marzio', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA', 'Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY 10016, USA'], 'affiliations': [{'raw_affiliation_string': 'Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY 10016, USA', 'institution_ids': ['https://openalex.org/I57206974']}, {'raw_affiliation_string': 'Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029816112', 'display_name': 'Nissa Carrodus', 'orcid': 'https://orcid.org/0009-0005-7108-8075'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Nissa Carrodus', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014893281', 'display_name': 'Steven Zuryn', 'orcid': 'https://orcid.org/0000-0002-3551-6790'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Steven Zuryn', 'raw_affiliation_strings': ['Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034919044', 'display_name': 'Michele Pagano', 'orcid': 'https://orcid.org/0000-0003-3210-2442'}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michele Pagano', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA', 'Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY 10016, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA', 'institution_ids': ['https://openalex.org/I57206974']}, {'raw_affiliation_string': 'Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY 10016, USA', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029211283', 'display_name': 'Robert G. Parton', 'orcid': 'https://orcid.org/0000-0002-7494-5248'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Robert G. Parton', 'raw_affiliation_strings': ['Centre for Microscopy and Microanalysis, University of Queensland, Brisbane, QLD, Australia', 'The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'Centre for Microscopy and Microanalysis, University of Queensland, Brisbane, QLD, Australia', 'institution_ids': ['https://openalex.org/I165143802']}, {'raw_affiliation_string': 'The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061877082', 'display_name': 'Michael Lazarou', 'orcid': 'https://orcid.org/0000-0003-2150-5545'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}, {'id': 'https://openalex.org/I2801239119', 'display_name': 'Australian Regenerative Medicine Institute', 'ror': 'https://ror.org/02qa5kg76', 'country_code': 'AU', 'type': 'facility', 'lineage': ['https://openalex.org/I2801037857', 'https://openalex.org/I2801239119', 'https://openalex.org/I56590836']}, {'id': 'https://openalex.org/I165779595', 'display_name': 'University of Melbourne', 'ror': 'https://ror.org/01ej9dk98', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165779595']}, {'id': 'https://openalex.org/I196021976', 'display_name': 'Walter and Eliza Hall Institute of Medical Research', 'ror': 'https://ror.org/01b6kha49', 'country_code': 'AU', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I196021976']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Michael Lazarou', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, 3068, Australia', 'Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia', 'Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, 3068, Australia', 'institution_ids': ['https://openalex.org/I56590836', 'https://openalex.org/I2801239119']}, {'raw_affiliation_string': 'Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia', 'institution_ids': ['https://openalex.org/I165779595']}, {'raw_affiliation_string': 'Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia', 'institution_ids': ['https://openalex.org/I196021976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050400735', 'display_name': 'S. Sean Millard', 'orcid': 'https://orcid.org/0000-0001-8573-4625'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Sean Millard', 'raw_affiliation_strings': ['Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia', 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}, {'raw_affiliation_string': 'Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100636153', 'display_name': 'Robert W. Taylor', 'orcid': 'https://orcid.org/0000-0002-7768-8873'}, 'institutions': [{'id': 'https://openalex.org/I4210138563', 'display_name': 'Wellcome Centre for Mitochondrial Research', 'ror': 'https://ror.org/03myjph80', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I4210138563', 'https://openalex.org/I84884186', 'https://openalex.org/I87048295']}, {'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2801663869', 'display_name': 'Newcastle upon Tyne Hospitals NHS Foundation Trust', 'ror': 'https://ror.org/05p40t847', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801663869']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Robert W. Taylor', 'raw_affiliation_strings': ['NHS Highly Specialised Service for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, UK', 'Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK'], 'affiliations': [{'raw_affiliation_string': 'Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK', 'institution_ids': ['https://openalex.org/I4210138563', 'https://openalex.org/I84884186']}, {'raw_affiliation_string': 'NHS Highly Specialised Service for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, UK', 'institution_ids': ['https://openalex.org/I2801663869']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019522016', 'display_name': 'Brett M. Collins', 'orcid': 'https://orcid.org/0000-0002-6070-3774'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Brett M. Collins', 'raw_affiliation_strings': ['The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103260951', 'display_name': 'Mathew V. Jones', 'orcid': 'https://orcid.org/0000-0003-2714-8411'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Mathew J.K. Jones', 'raw_affiliation_strings': ['The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4102, Australia'], 'affiliations': [{'raw_affiliation_string': 'The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4102, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063634904', 'display_name': 'Julia K. Pagan', 'orcid': 'https://orcid.org/0000-0002-7079-6388'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': True, 'raw_author_name': 'Julia K. Pagan', 'raw_affiliation_strings': ['School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4102, Australia', 'The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}, {'raw_affiliation_string': 'The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4102, Australia', 'institution_ids': ['https://openalex.org/I165143802']}, {'raw_affiliation_string': 'The University of Queensland, Institute for Molecular Bioscience, Brisbane, QLD 4072, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 10, 'corresponding_author_ids': ['https://openalex.org/A5063634904'], 'corresponding_institution_ids': ['https://openalex.org/I165143802'], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.935589, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 83, 'max': 85}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10587', 'display_name': 'Autophagy in Disease and Therapy', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10587', 'display_name': 'Autophagy in Disease and Therapy', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Disease', 'score': 0.9891, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779324830', 'wikidata': 'https://www.wikidata.org/wiki/Q1806192', 'display_name': 'Mitophagy', 'level': 4, 'score': 0.99761736}, {'id': 'https://openalex.org/C203522944', 'wikidata': 'https://www.wikidata.org/wiki/Q288322', 'display_name': 'Autophagy', 'level': 3, 'score': 0.8839115}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.8096595}, {'id': 'https://openalex.org/C134459356', 'wikidata': 'https://www.wikidata.org/wiki/Q4274835', 'display_name': 'Ubiquitin ligase', 'level': 4, 'score': 0.7852106}, {'id': 'https://openalex.org/C25602115', 'wikidata': 'https://www.wikidata.org/wiki/Q407111', 'display_name': 'Ubiquitin', 'level': 3, 'score': 0.71789706}, {'id': 'https://openalex.org/C28859421', 'wikidata': 'https://www.wikidata.org/wiki/Q39572', 'display_name': 'Mitochondrion', 'level': 2, 'score': 0.6870434}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5259895}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.35572618}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.24131194}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.23648044}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.051417857}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.10.12.511867', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/10/12/2022.10.12.511867.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.15252/embj.2022112767', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.2022112767', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://eprints.ncl.ac.uk/fulltext.aspx?url=291510/A8C3D449-0670-4841-AA41-D97157D57EFC.pdf&pub_id=291510', 'pdf_url': 'https://eprints.ncl.ac.uk/fulltext.aspx?url=291510/A8C3D449-0670-4841-AA41-D97157D57EFC.pdf&pub_id=291510', 'source': {'id': 'https://openalex.org/S4306402485', 'display_name': 'Newcastle University ePrints (Newcastle Univesity)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I84884186', 'host_organization_name': 'Newcastle University', 'host_organization_lineage': ['https://openalex.org/I84884186'], 'host_organization_lineage_names': ['Newcastle University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.10.12.511867', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/10/12/2022.10.12.511867.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1749022239', 'https://openalex.org/W1965827991', 'https://openalex.org/W1968843321', 'https://openalex.org/W1991533918', 'https://openalex.org/W2012967220', 'https://openalex.org/W2034767282', 'https://openalex.org/W2038834667', 'https://openalex.org/W2040031153', 'https://openalex.org/W2044829505', 'https://openalex.org/W2045012604', 'https://openalex.org/W2047242847', 'https://openalex.org/W2048611034', 'https://openalex.org/W2050723187', 'https://openalex.org/W2062830884', 'https://openalex.org/W2068700852', 'https://openalex.org/W2070098827', 'https://openalex.org/W2076194625', 'https://openalex.org/W2081051270', 'https://openalex.org/W2089612936', 'https://openalex.org/W2103230459', 'https://openalex.org/W2118094114', 'https://openalex.org/W2122556106', 'https://openalex.org/W2127440157', 'https://openalex.org/W2144625075', 'https://openalex.org/W2144670533', 'https://openalex.org/W2146122852', 'https://openalex.org/W2155015733', 'https://openalex.org/W2158535498', 'https://openalex.org/W2164945122', 'https://openalex.org/W2168974130', 'https://openalex.org/W2376573086', 'https://openalex.org/W2593462505', 'https://openalex.org/W2605825818', 'https://openalex.org/W2610895525', 'https://openalex.org/W2735816534', 'https://openalex.org/W2783409125', 'https://openalex.org/W2787965853', 'https://openalex.org/W2788644497', 'https://openalex.org/W2912761569', 'https://openalex.org/W2913650647', 'https://openalex.org/W2949223833', 'https://openalex.org/W2951149542', 'https://openalex.org/W2969847823', 'https://openalex.org/W3011835552', 'https://openalex.org/W3016185846', 'https://openalex.org/W3033262131', 'https://openalex.org/W3121008513', 'https://openalex.org/W3127992352', 'https://openalex.org/W3150184953', 'https://openalex.org/W3156007823', 'https://openalex.org/W3161391707', 'https://openalex.org/W3177828909', 'https://openalex.org/W3202105508', 'https://openalex.org/W4205735374', 'https://openalex.org/W4281790889'], 'related_works': ['https://openalex.org/W4401812143', 'https://openalex.org/W4313566801', 'https://openalex.org/W2997013829', 'https://openalex.org/W2524645060', 'https://openalex.org/W2500933326', 'https://openalex.org/W2102368462', 'https://openalex.org/W2092699248', 'https://openalex.org/W2054919679', 'https://openalex.org/W1970861248', 'https://openalex.org/W1968811439'], 'abstract_inverted_index': {'Abstract': [0], 'Cells': [1], 'selectively': [2], 'remove': [3, 42], 'damaged': [4], 'or': [5, 127], 'excessive': [6, 154], 'mitochondria': [7, 45], 'through': [8], 'mitophagy,': [9], 'a': [10, 138], 'specialized': [11], 'form': [12], 'of': [13, 86, 97, 107, 131, 167], 'autophagy,': [14], 'to': [15, 26, 49, 71, 93], 'maintain': [16], 'mitochondrial': [17, 34, 51, 73], 'quality': [18], 'and': [19, 33, 79, 84, 91, 133, 148, 151, 169], 'quantity.': [20], 'Mitophagy': [21], 'is': [22, 163], 'induced': [23], 'in': [24, 76, 157], 'response': [25], 'diverse': [27], 'conditions,': [28], 'including': [29], 'hypoxia,': [30], 'cellular': [31], 'differentiation,': [32], 'damage.': [35], 'However,': [36], 'the': [37, 72, 81, 87, 121, 129, 158], 'mechanisms': [38], 'by': [39, 165], 'which': [40], 'cells': [41, 78], 'specific': [43], 'dysfunctional': [44], 'under': [46], 'steady-state': [47], 'conditions': [48], 'fine-tune': [50], 'content': [52], 'are': [53], 'not': [54, 117], 'well': [55], 'understood.': [56], 'Here,': [57], 'we': [58, 136], 'report': [59], 'that': [60, 109, 141, 153], 'SCF': [61, 123], 'FBXL4': [62, 108], ',': [63], 'an': [64], 'SKP1/CUL1/F-box': [65], 'protein': [66], 'ubiquitin': [67, 124], 'ligase': [68, 125], 'complex,': [69], 'localizes': [70], 'outer': [74], 'membrane': [75], 'unstressed': [77], 'mediates': [80], 'constitutive': [82], 'ubiquitylation': [83], 'degradation': [85, 130], 'mitophagy': [88, 144, 156], 'receptors': [89], 'NIX': [90, 132, 147, 168], 'BNIP3': [92, 149, 170], 'suppress': [94], 'basal': [95, 155], 'levels': [96], 'mitophagy.': [98], 'We': [99], 'demonstrate': [100], 'that,': [101], 'unlike': [102], 'wild-type': [103], 'FBXL4,': [104], 'pathogenic': [105], 'variants': [106], 'cause': [110], 'encephalopathic': [111], 'mtDNA': [112, 160], 'depletion': [113, 161], 'syndrome': [114, 162], '(MTDPS13),': [115], 'do': [116], 'efficiently': [118], 'interact': [119], 'with': [120], 'core': [122], 'machinery': [126], 'mediate': [128], 'BNIP3.': [134], 'Thus,': [135], 'reveal': [137], 'molecular': [139], 'mechanism': [140], 'actively': [142], 'suppresses': [143], 'via': [145], 'preventing': [146], 'accumulation': [150], 'propose': [152], 'FBXL4-associated': [159], 'caused': [164], 'dysregulation': [166], 'turnover.': [171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4304889421', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}], 'updated_date': '2024-12-09T07:45:12.852221', 'created_date': '2022-10-13'}