Publication Information

{'id': 'https://openalex.org/W4304116770', 'doi': 'https://doi.org/10.1007/s13258-022-01318-w', 'title': 'FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts', 'display_name': 'FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts', 'publication_year': 2022, 'publication_date': '2022-10-10', 'ids': {'openalex': 'https://openalex.org/W4304116770', 'doi': 'https://doi.org/10.1007/s13258-022-01318-w', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36214983'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s13258-022-01318-w', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31122987', 'display_name': 'Genes & Genomics', 'issn_l': '1976-9571', 'issn': ['1976-9571', '2092-9293'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091499185', 'display_name': 'Hanhan Xie', 'orcid': 'https://orcid.org/0009-0007-0617-2582'}, 'institutions': [{'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hanhan Xie', 'raw_affiliation_strings': ['School of Laboratory Medicine, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'School of Laboratory Medicine, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I207528943']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101648572', 'display_name': 'Yun Lei', 'orcid': 'https://orcid.org/0000-0003-4572-6078'}, 'institutions': [{'id': 'https://openalex.org/I4210165038', 'display_name': 'University of Chinese Academy of Sciences', 'ror': 'https://ror.org/05qbk4x57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I19820366', 'https://openalex.org/I4210165038']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yun Lei', 'raw_affiliation_strings': ['Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China'], 'affiliations': [{'raw_affiliation_string': 'Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China', 'institution_ids': ['https://openalex.org/I4210165038']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045933170', 'display_name': 'Yushan Mao', 'orcid': 'https://orcid.org/0000-0002-5539-8832'}, 'institutions': [{'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yushan Mao', 'raw_affiliation_strings': ['School of Basic Medical Science, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'School of Basic Medical Science, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I207528943']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110541240', 'display_name': 'Jingbin Lan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jingbin Lan', 'raw_affiliation_strings': ['School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I207528943']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100697694', 'display_name': 'Jing Yang', 'orcid': 'https://orcid.org/0000-0003-1453-1358'}, 'institutions': [{'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jing Yang', 'raw_affiliation_strings': ['School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I207528943']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090631189', 'display_name': 'Hui Quan', 'orcid': 'https://orcid.org/0000-0001-8506-107X'}, 'institutions': [{'id': 'https://openalex.org/I157771985', 'display_name': 'China National Nuclear Corporation', 'ror': 'https://ror.org/01d5ymp84', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I157771985']}, {'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hui Quan', 'raw_affiliation_strings': ['The Second Affiliated Hospital of Chengdu Medical College, China Nation Nuclear Corporation 416 Hospital, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'The Second Affiliated Hospital of Chengdu Medical College, China Nation Nuclear Corporation 416 Hospital, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I157771985', 'https://openalex.org/I207528943']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101531993', 'display_name': 'Tao Zhang', 'orcid': 'https://orcid.org/0000-0003-4299-3568'}, 'institutions': [{'id': 'https://openalex.org/I207528943', 'display_name': 'Chengdu Medical College', 'ror': 'https://ror.org/01c4jmp52', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I207528943']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Tao Zhang', 'raw_affiliation_strings': ['School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China'], 'affiliations': [{'raw_affiliation_string': 'School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China', 'institution_ids': ['https://openalex.org/I207528943']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2590, 'currency': 'EUR', 'value_usd': 3190, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.908, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.696311, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 85}, 'biblio': {'volume': '44', 'issue': '12', 'first_page': '1531', 'last_page': '1541'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11051', 'display_name': 'Sirtuins and Resveratrol in Medicine', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2717', 'display_name': 'Geriatrics and Gerontology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11051', 'display_name': 'Sirtuins and Resveratrol in Medicine', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2717', 'display_name': 'Geriatrics and Gerontology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10587', 'display_name': 'Autophagy in Disease and Therapy', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11457', 'display_name': 'Adipose Tissue and Metabolism', 'score': 0.993, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-associated-fibroblasts', 'display_name': 'Cancer-Associated Fibroblasts', 'score': 0.6399648}], 'concepts': [{'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.7738033}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.76543343}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.738057}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.717092}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6634469}, {'id': 'https://openalex.org/C2909706936', 'wikidata': 'https://www.wikidata.org/wiki/Q42417562', 'display_name': 'Cancer-Associated Fibroblasts', 'level': 4, 'score': 0.6399648}, {'id': 'https://openalex.org/C96232424', 'wikidata': 'https://www.wikidata.org/wiki/Q4118072', 'display_name': 'Cancer cell', 'level': 3, 'score': 0.59608144}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.5423669}, {'id': 'https://openalex.org/C75520062', 'wikidata': 'https://www.wikidata.org/wiki/Q15321392', 'display_name': 'NAD+ kinase', 'level': 3, 'score': 0.46838242}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.07466668}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.056352884}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.051856518}], 'mesh': [{'descriptor_ui': 'D000072645', 'descriptor_name': 'Cancer-Associated Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015179', 'descriptor_name': 'Colorectal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000178', 'descriptor_name': 'Acrylamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000178', 'descriptor_name': 'Acrylamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000072645', 'descriptor_name': 'Cancer-Associated Fibroblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000072645', 'descriptor_name': 'Cancer-Associated Fibroblasts', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D015179', 'descriptor_name': 'Colorectal Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009243', 'descriptor_name': 'NAD', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009243', 'descriptor_name': 'NAD', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009243', 'descriptor_name': 'NAD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010880', 'descriptor_name': 'Piperidines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010880', 'descriptor_name': 'Piperidines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s13258-022-01318-w', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31122987', 'display_name': 'Genes & Genomics', 'issn_l': '1976-9571', 'issn': ['1976-9571', '2092-9293'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36214983', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.65, 'id': 'https://metadata.un.org/sdg/1', 'display_name': 'No poverty'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81773143'}], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1977381126', 'https://openalex.org/W1977692564', 'https://openalex.org/W2002811789', 'https://openalex.org/W2005789183', 'https://openalex.org/W2006170651', 'https://openalex.org/W2020914260', 'https://openalex.org/W2021958704', 'https://openalex.org/W2028178274', 'https://openalex.org/W2033278321', 'https://openalex.org/W2042081254', 'https://openalex.org/W2050303562', 'https://openalex.org/W2051020739', 'https://openalex.org/W2072112559', 'https://openalex.org/W2077834313', 'https://openalex.org/W2078502914', 'https://openalex.org/W2106817237', 'https://openalex.org/W2155076776', 'https://openalex.org/W2284984697', 'https://openalex.org/W2400022769', 'https://openalex.org/W2512899508', 'https://openalex.org/W2535762504', 'https://openalex.org/W2547358231', 'https://openalex.org/W2576118052', 'https://openalex.org/W2584020663', 'https://openalex.org/W2753965489', 'https://openalex.org/W2891614594', 'https://openalex.org/W2901515128', 'https://openalex.org/W2969669738', 'https://openalex.org/W2986485899', 'https://openalex.org/W3013845627', 'https://openalex.org/W3092621787', 'https://openalex.org/W3101848977', 'https://openalex.org/W4211090034'], 'related_works': ['https://openalex.org/W4386836027', 'https://openalex.org/W4313339714', 'https://openalex.org/W4312823718', 'https://openalex.org/W4200547365', 'https://openalex.org/W3205593170', 'https://openalex.org/W3096600782', 'https://openalex.org/W3006386809', 'https://openalex.org/W2362034133', 'https://openalex.org/W2256616461', 'https://openalex.org/W2158770220'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4304116770', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-25T08:22:36.021244', 'created_date': '2022-10-11'}