Title: Clinical Evaluation of a Lysis-Centrifugation Technique for the Detection of Septicemia
Abstract:A commercially available lysis-centrifugation blood culture system was compared with a two-bottle broth-culture system employing 100 mL of broth and 10 mL of blood per bottle to analyze 1,913 blood sp...A commercially available lysis-centrifugation blood culture system was compared with a two-bottle broth-culture system employing 100 mL of broth and 10 mL of blood per bottle to analyze 1,913 blood specimens. Of 154 clinically significant isolates, 89% were detected by the lysis-centrifugation technique, and 73% were detected by the broth-culture method. Twenty-seven percent of the organisms were detected only by the lysis-centrifugation technique, and 11% were detected only by the broth system. Fifteen polymicrobial cultures were encountered; the lysis-centrifugation technique detected 93% of the organisms in these cultures, while the broth-culture method detected only 20%. Isolated colonies of clinically important organisms were available 30 hours earlier with the lysis-centrifugation technique. These results suggest that the lysis-centrifugation technique may provide a substantial improvement over conventional methods for blood cultures. (<i>JAMA</i>1983;250:2185-2188)Read More
Publication Year: 1983
Publication Date: 1983-10-28
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 14
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot