Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4297516831', 'doi': 'https://doi.org/10.1101/2022.09.28.509835', 'title': 'A Single-Cell Level Comparison of Human Inner Ear Organoids and the Human Cochlea and Vestibular Organs', 'display_name': 'A Single-Cell Level Comparison of Human Inner Ear Organoids and the Human Cochlea and Vestibular Organs', 'publication_year': 2022, 'publication_date': '2022-09-28', 'ids': {'openalex': 'https://openalex.org/W4297516831', 'doi': 'https://doi.org/10.1101/2022.09.28.509835'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.09.28.509835', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/09/28/2022.09.28.509835.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'type': 'preprint', 'type_crossref': 'posted-content', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/09/28/2022.09.28.509835.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001958936', 'display_name': 'Wouter H. van der Valk', 'orcid': 'https://orcid.org/0000-0001-5661-7796'}, 'institutions': [{'id': 'https://openalex.org/I4210150980', 'display_name': "Boston Children's Museum", 'ror': 'https://ror.org/051vg8924', 'country_code': 'US', 'type': 'archive', 'lineage': ['https://openalex.org/I4210150980']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}, {'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL', 'US'], 'is_corresponding': False, 'raw_author_name': 'Wouter H. van der Valk', 'raw_affiliation_strings': ['Boston', "Boston Children's Hospital", 'Department of Otolaryngology', 'Department of Otorhinolaryngology and Head & Neck Surgery', 'Leiden', 'Leiden University Medical Center'], 'affiliations': [{'raw_affiliation_string': 'Leiden', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otolaryngology', 'institution_ids': []}, {'raw_affiliation_string': "Boston Children's Hospital", 'institution_ids': ['https://openalex.org/I4210150980', 'https://openalex.org/I1288882113']}, {'raw_affiliation_string': 'Boston', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otorhinolaryngology and Head & Neck Surgery', 'institution_ids': []}, {'raw_affiliation_string': 'Leiden University Medical Center', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015849465', 'display_name': 'Edward S. A. van Beelen', 'orcid': 'https://orcid.org/0000-0002-6952-9098'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Edward S.A. van Beelen', 'raw_affiliation_strings': ['Department of Otorhinolaryngology and Head & Neck Surgery', 'Leiden', 'Leiden University Medical Center'], 'affiliations': [{'raw_affiliation_string': 'Leiden', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otorhinolaryngology and Head & Neck Surgery', 'institution_ids': []}, {'raw_affiliation_string': 'Leiden University Medical Center', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069325291', 'display_name': 'Matthew R. Steinhart', 'orcid': 'https://orcid.org/0000-0002-9619-6057'}, 'institutions': [{'id': 'https://openalex.org/I2802576979', 'display_name': 'Indianapolis Zoo', 'ror': 'https://ror.org/01k9v9b21', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802576979']}, {'id': 'https://openalex.org/I4210150980', 'display_name': "Boston Children's Museum", 'ror': 'https://ror.org/051vg8924', 'country_code': 'US', 'type': 'archive', 'lineage': ['https://openalex.org/I4210150980']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}, {'id': 'https://openalex.org/I592451', 'display_name': 'Indiana University', 'ror': 'https://ror.org/01kg8sb98', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I592451']}, {'id': 'https://openalex.org/I4210153792', 'display_name': 'University School', 'ror': 'https://ror.org/05ap66461', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I4210153792']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Matthew R. Steinhart', 'raw_affiliation_strings': ['Boston', "Boston Children's Hospital", 'Department of Otolaryngology', 'Department of Otolaryngology-Head and Neck Surgery', 'Indiana University School of Medicine', 'Indianapolis', 'Medical Neuroscience Graduate Program'], 'affiliations': [{'raw_affiliation_string': 'Boston', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otolaryngology', 'institution_ids': []}, {'raw_affiliation_string': 'Indianapolis', 'institution_ids': ['https://openalex.org/I2802576979']}, {'raw_affiliation_string': "Boston Children's Hospital", 'institution_ids': ['https://openalex.org/I4210150980', 'https://openalex.org/I1288882113']}, {'raw_affiliation_string': 'Indiana University School of Medicine', 'institution_ids': ['https://openalex.org/I592451', 'https://openalex.org/I4210153792']}, {'raw_affiliation_string': 'Medical Neuroscience Graduate Program', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otolaryngology-Head and Neck Surgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000369222', 'display_name': 'Carl Nist-Lund', 'orcid': 'https://orcid.org/0000-0002-0224-7387'}, 'institutions': [{'id': 'https://openalex.org/I4210150980', 'display_name': "Boston Children's Museum", 'ror': 'https://ror.org/051vg8924', 'country_code': 'US', 'type': 'archive', 'lineage': ['https://openalex.org/I4210150980']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Carl Nist-Lund', 'raw_affiliation_strings': ['Boston', "Boston Children's Hospital", 'Department of Otolaryngology'], 'affiliations': [{'raw_affiliation_string': "Boston Children's Hospital", 'institution_ids': ['https://openalex.org/I4210150980', 'https://openalex.org/I1288882113']}, {'raw_affiliation_string': 'Boston', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otolaryngology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077702089', 'display_name': 'John C.M.J. de Groot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'John C.M.J. de Groot', 'raw_affiliation_strings': ['Department of Otorhinolaryngology and Head & Neck Surgery', 'Leiden', 'Leiden University Medical Center'], 'affiliations': [{'raw_affiliation_string': 'Leiden', 'institution_ids': []}, {'raw_affiliation_string': 'Leiden University Medical Center', 'institution_ids': ['https://openalex.org/I2800006345']}, {'raw_affiliation_string': 'Department of Otorhinolaryngology and Head & Neck Surgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045756053', 'display_name': 'Peter Paul G. van Benthem', 'orcid': 'https://orcid.org/0000-0002-7946-1912'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Peter Paul G. van Benthem', 'raw_affiliation_strings': ['Department of Otorhinolaryngology and Head & Neck Surgery', 'Leiden', 'Leiden University Medical Center'], 'affiliations': [{'raw_affiliation_string': 'Leiden University Medical Center', 'institution_ids': ['https://openalex.org/I2800006345']}, {'raw_affiliation_string': 'Leiden', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Otorhinolaryngology and Head & Neck Surgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086772228', 'display_name': 'Karl R. Koehler', 'orcid': 'https://orcid.org/0000-0002-0685-538X'}, 'institutions': [{'id': 'https://openalex.org/I4210166946', 'display_name': 'Imaging Center', 'ror': 'https://ror.org/05hsqsk33', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166946']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I2802576979', 'display_name': 'Indianapolis Zoo', 'ror': 'https://ror.org/01k9v9b21', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802576979']}, {'id': 'https://openalex.org/I4210150980', 'display_name': "Boston Children's Museum", 'ror': 'https://ror.org/051vg8924', 'country_code': 'US', 'type': 'archive', 'lineage': ['https://openalex.org/I4210150980']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}, {'id': 'https://openalex.org/I592451', 'display_name': 'Indiana University', 'ror': 'https://ror.org/01kg8sb98', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I592451']}, {'id': 'https://openalex.org/I4210153792', 'display_name': 'University School', 'ror': 'https://ror.org/05ap66461', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I4210153792']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Karl R. Koehler', 'raw_affiliation_strings': ['Boston', "Boston Children's Hospital", 'Department of Otolaryngology', 'Department of Otolaryngology-Head and Neck Surgery', 'Department of Plastic and Oral Surgery', 'F.M. Kirby Neurobiology Center', 'Harvard Medical School', 'Indiana University School of Medicine', 'Indianapolis'], 'affiliations': [{'raw_affiliation_string': 'F.M. Kirby Neurobiology Center', 'institution_ids': ['https://openalex.org/I4210166946']}, {'raw_affiliation_string': 'Harvard Medical School', 'institution_ids': ['https://openalex.org/I136199984']}, {'raw_affiliation_string': 'Department of Otolaryngology', 'institution_ids': []}, {'raw_affiliation_string': 'Indianapolis', 'institution_ids': ['https://openalex.org/I2802576979']}, {'raw_affiliation_string': 'Department of Otolaryngology-Head and Neck Surgery', 'institution_ids': []}, {'raw_affiliation_string': "Boston Children's Hospital", 'institution_ids': ['https://openalex.org/I4210150980', 'https://openalex.org/I1288882113']}, {'raw_affiliation_string': 'Indiana University School of Medicine', 'institution_ids': ['https://openalex.org/I592451', 'https://openalex.org/I4210153792']}, {'raw_affiliation_string': 'Department of Plastic and Oral Surgery', 'institution_ids': []}, {'raw_affiliation_string': 'Boston', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031812895', 'display_name': 'Heiko Locher', 'orcid': 'https://orcid.org/0000-0002-4174-0270'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}, {'id': 'https://openalex.org/I2801134892', 'display_name': 'Novo Nordisk Foundation', 'ror': 'https://ror.org/04txyc737', 'country_code': 'DK', 'type': 'facility', 'lineage': ['https://openalex.org/I2801134892']}, {'id': 'https://openalex.org/I2802640032', 'display_name': 'Foundation Center', 'ror': 'https://ror.org/0377f6951', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802640032']}], 'countries': ['DK', 'NL', 'US'], 'is_corresponding': False, 'raw_author_name': 'Heiko Locher', 'raw_affiliation_strings': ['Department of Otorhinolaryngology and Head & Neck Surgery', 'Leiden', 'Leiden University Medical Center', 'The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW)'], 'affiliations': [{'raw_affiliation_string': 'Leiden', 'institution_ids': []}, {'raw_affiliation_string': 'Leiden University Medical Center', 'institution_ids': ['https://openalex.org/I2800006345']}, {'raw_affiliation_string': 'Department of Otorhinolaryngology and Head & Neck Surgery', 'institution_ids': []}, {'raw_affiliation_string': 'The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW)', 'institution_ids': ['https://openalex.org/I2801134892', 'https://openalex.org/I2802640032']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 10, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.703297, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 72, 'max': 78}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10334', 'display_name': 'Cochlear Neuropathy and Hearing Loss Mechanisms', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10334', 'display_name': 'Cochlear Neuropathy and Hearing Loss Mechanisms', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11692', 'display_name': 'Effects of Noise Pollution on Health and Well-being', 'score': 0.9885, 'subfield': {'id': 'https://openalex.org/subfields/3616', 'display_name': 'Speech and Hearing'}, 'field': {'id': 'https://openalex.org/fields/36', 'display_name': 'Health Professions'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10283', 'display_name': 'Impact of Hearing Loss on Cognitive Function', 'score': 0.9773, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/inner-ear-development', 'display_name': 'Inner Ear Development', 'score': 0.615581}, {'id': 'https://openalex.org/keywords/auditory-processing', 'display_name': 'Auditory Processing', 'score': 0.514451}, {'id': 'https://openalex.org/keywords/cell-type', 'display_name': 'Cell type', 'score': 0.5115529}, {'id': 'https://openalex.org/keywords/organoid', 'display_name': 'Organoid', 'score': 0.51146185}, {'id': 'https://openalex.org/keywords/auditory-system', 'display_name': 'Auditory System', 'score': 0.510028}, {'id': 'https://openalex.org/keywords/hearing-loss', 'display_name': 'Hearing Loss', 'score': 0.500056}], 'concepts': [{'id': 'https://openalex.org/C2778500370', 'wikidata': 'https://www.wikidata.org/wiki/Q212344', 'display_name': 'Inner ear', 'level': 2, 'score': 0.96937406}, {'id': 'https://openalex.org/C2780130748', 'wikidata': 'https://www.wikidata.org/wiki/Q317857', 'display_name': 'Cochlea', 'level': 2, 'score': 0.78036284}, {'id': 'https://openalex.org/C2778585322', 'wikidata': 'https://www.wikidata.org/wiki/Q1566641', 'display_name': 'Hair cell', 'level': 3, 'score': 0.6726709}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6686578}, {'id': 'https://openalex.org/C190041318', 'wikidata': 'https://www.wikidata.org/wiki/Q596832', 'display_name': 'Vestibular system', 'level': 2, 'score': 0.6475564}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.5767138}, {'id': 'https://openalex.org/C189014844', 'wikidata': 'https://www.wikidata.org/wiki/Q189118', 'display_name': 'Cell type', 'level': 3, 'score': 0.5115529}, {'id': 'https://openalex.org/C31695470', 'wikidata': 'https://www.wikidata.org/wiki/Q11293125', 'display_name': 'Organoid', 'level': 2, 'score': 0.51146185}, {'id': 'https://openalex.org/C107459253', 'wikidata': 'https://www.wikidata.org/wiki/Q674925', 'display_name': 'Induced pluripotent stem cell', 'level': 4, 'score': 0.41558453}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.39318866}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.34391218}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.26341027}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.26052374}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.2341933}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.14514449}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.11551377}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.08790892}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.09.28.509835', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/09/28/2022.09.28.509835.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/2022.09.28.509835', 'pdf_url': 'https://www.biorxiv.org/content/biorxiv/early/2022/09/28/2022.09.28.509835.full.pdf', 'source': {'id': 'https://openalex.org/S4306402567', 'display_name': 'bioRxiv (Cold Spring Harbor Laboratory)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2750212522', 'host_organization_name': 'Cold Spring Harbor Laboratory', 'host_organization_lineage': ['https://openalex.org/I2750212522'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.71, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 84, 'referenced_works': ['https://openalex.org/W1586288730', 'https://openalex.org/W1767363628', 'https://openalex.org/W1802031919', 'https://openalex.org/W1843045369', 'https://openalex.org/W1966000642', 'https://openalex.org/W1973685164', 'https://openalex.org/W1986463751', 'https://openalex.org/W1997609921', 'https://openalex.org/W2008208203', 'https://openalex.org/W2025173623', 'https://openalex.org/W2035913145', 'https://openalex.org/W2059605418', 'https://openalex.org/W2066054477', 'https://openalex.org/W2068559327', 'https://openalex.org/W2071014369', 'https://openalex.org/W2078117691', 'https://openalex.org/W2088483102', 'https://openalex.org/W2092911887', 'https://openalex.org/W2123396085', 'https://openalex.org/W2133151169', 'https://openalex.org/W2133397439', 'https://openalex.org/W2139722243', 'https://openalex.org/W2144287136', 'https://openalex.org/W2147839272', 'https://openalex.org/W2163733911', 'https://openalex.org/W2169514219', 'https://openalex.org/W2175664647', 'https://openalex.org/W2538495032', 'https://openalex.org/W2555612556', 'https://openalex.org/W2610506730', 'https://openalex.org/W2754552929', 'https://openalex.org/W2759937524', 'https://openalex.org/W2764154044', 'https://openalex.org/W2785085486', 'https://openalex.org/W2793779450', 'https://openalex.org/W2863240870', 'https://openalex.org/W2895471626', 'https://openalex.org/W2897592834', 'https://openalex.org/W2898549090', 'https://openalex.org/W2901166120', 'https://openalex.org/W2906213364', 'https://openalex.org/W2913348902', 'https://openalex.org/W2936811117', 'https://openalex.org/W2947937464', 'https://openalex.org/W2949693884', 'https://openalex.org/W2958938850', 'https://openalex.org/W2969570008', 'https://openalex.org/W2971388421', 'https://openalex.org/W2973437321', 'https://openalex.org/W2977703849', 'https://openalex.org/W2978515961', 'https://openalex.org/W2984472267', 'https://openalex.org/W2990011308', 'https://openalex.org/W2995898393', 'https://openalex.org/W2997280954', 'https://openalex.org/W3003720994', 'https://openalex.org/W3006650868', 'https://openalex.org/W3015184839', 'https://openalex.org/W3023126733', 'https://openalex.org/W3024295806', 'https://openalex.org/W3026116641', 'https://openalex.org/W3032142305', 'https://openalex.org/W3036062897', 'https://openalex.org/W3037529416', 'https://openalex.org/W3045329808', 'https://openalex.org/W3084227162', 'https://openalex.org/W3093110297', 'https://openalex.org/W3093492713', 'https://openalex.org/W3112932588', 'https://openalex.org/W3114991344', 'https://openalex.org/W3119231555', 'https://openalex.org/W3126148307', 'https://openalex.org/W3126365850', 'https://openalex.org/W3129806604', 'https://openalex.org/W3144771484', 'https://openalex.org/W3160698231', 'https://openalex.org/W3165670466', 'https://openalex.org/W3180493357', 'https://openalex.org/W3184560250', 'https://openalex.org/W3196820591', 'https://openalex.org/W3198426699', 'https://openalex.org/W3203654614', 'https://openalex.org/W3211022207', 'https://openalex.org/W4206402298'], 'related_works': ['https://openalex.org/W4297516831', 'https://openalex.org/W3142079209', 'https://openalex.org/W3123984149', 'https://openalex.org/W2946349268', 'https://openalex.org/W2892032098', 'https://openalex.org/W2610506730', 'https://openalex.org/W2571699119', 'https://openalex.org/W2052692688', 'https://openalex.org/W2019942860', 'https://openalex.org/W2007367953'], 'abstract_inverted_index': {'Summary': [0], 'Genetic': [1], 'inner': [2, 26, 46, 61, 78, 106, 114, 127, 131, 147, 168, 179, 190], 'ear': [3, 27, 47, 62, 115, 132, 148, 169, 180], 'disorders': [4], 'are': [5], 'among': [6], 'the': [7, 25, 42, 74, 101, 113, 124, 130, 153, 183, 189], 'most': [8], 'common': [9], 'congenital': [10], 'abnormalities': [11], 'and': [12, 17, 36, 70, 91, 104, 119, 138, 157, 185], 'lead': [13], 'to': [14, 40, 123, 160], 'hearing': [15, 162], 'loss': [16], 'balance': [18], 'disorders.': [19, 48], 'Ideally,': [20], 'tissue': [21], 'culture': [22], 'models': [23], 'of': [24, 45, 55, 76, 86, 100, 155, 176, 188], 'should': [28], 'contain': [29, 134], 'a': [30, 96], 'functional': [31], 'unit': [32], 'combining': [33], 'otic': [34], 'sensory': [35, 184], 'nonsensory': [37, 186], 'cell': [38, 52, 149], 'types': [39], 'recapitulate': [41], 'varied': [43], 'etiologies': [44], 'Here,': [49], 'we': [50, 108, 151], 'evaluated': [51], 'type': [53, 136, 139], 'diversity': [54], 'late-stage': [56], 'human': [57, 102, 126, 167], 'pluripotent': [58], 'stem': [59], 'cell-derived': [60], 'organoids': [63, 116, 133, 170], 'using': [64, 166], 'single-cell': [65, 97], 'transcriptomic': [66, 98], 'analysis,': [67], 'electron': [68], 'microscopy': [69], 'immunohistochemistry.': [71], 'We': [72], 'observed': [73], 'induction': [75, 85], 'on-target': [77], 'ear-related': [79], 'periotic': [80], 'mesenchymal': [81], 'cells': [82], 'alongside': [83], 'off-target': [84], 'skeletal': [87], 'myocytes,': [88], 'endothelial': [89], 'cells,': [90], 'ependymal': [92], 'cells.': [93, 143], 'By': [94], 'constructing': [95], 'atlas': [99], 'fetal': [103], 'adult': [105], 'ear,': [107], 'show': [109], 'that': [110], 'epithelium': [111], 'in': [112, 182], 'contains': [117], 'cochlear': [118], 'vestibular': [120, 141], 'identities': [121], 'similar': [122], 'developing': [125], 'ear.': [128, 191], 'Moreover,': [129], 'immature': [135], 'I': [137], 'II': [140], 'hair': [142], 'Within': [144], 'these': [145], 'putative': [146], 'types,': [150], 'confirmed': [152], 'expression': [154], 'genes': [156], 'proteins': [158], 'linked': [159], 'sensorineural': [161], 'loss.': [163], 'This': [164], 'approach': [165], 'would': [171], 'allow': [172], 'for': [173], 'disease': [174], 'modeling': [175], 'specific': [177], 'genetic': [178], 'pathologies': [181], 'domains': [187]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4297516831', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}], 'updated_date': '2024-09-19T21:10:54.770307', 'created_date': '2022-09-29'}