Publication Information

{'id': 'https://openalex.org/W4295080856', 'doi': 'https://doi.org/10.3390/molecules27175730', 'title': 'Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches', 'display_name': 'Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches', 'publication_year': 2022, 'publication_date': '2022-09-05', 'ids': {'openalex': 'https://openalex.org/W4295080856', 'doi': 'https://doi.org/10.3390/molecules27175730', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36080493'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules27175730', 'pdf_url': 'https://www.mdpi.com/1420-3049/27/17/5730/pdf?version=1662455892', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1420-3049/27/17/5730/pdf?version=1662455892', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5082042907', 'display_name': 'Mamello Sekhoacha', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I26999989', 'display_name': 'University of the Free State', 'ror': 'https://ror.org/009xwd568', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26999989']}], 'countries': ['ZA'], 'is_corresponding': True, 'raw_author_name': 'Mamello Sekhoacha', 'raw_affiliation_strings': ['Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I26999989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079253398', 'display_name': 'Keamogetswe Riet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I110603874', 'display_name': 'Central University of Technology', 'ror': 'https://ror.org/033z08192', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I110603874']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Keamogetswe Riet', 'raw_affiliation_strings': ['Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I110603874']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064965883', 'display_name': 'Paballo Motloung', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I110603874', 'display_name': 'Central University of Technology', 'ror': 'https://ror.org/033z08192', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I110603874']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Paballo Motloung', 'raw_affiliation_strings': ['Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I110603874']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037483024', 'display_name': 'Lemohang Gumenku', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I110603874', 'display_name': 'Central University of Technology', 'ror': 'https://ror.org/033z08192', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I110603874']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Lemohang Gumenku', 'raw_affiliation_strings': ['Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I110603874']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068369359', 'display_name': 'Ayodeji M. Adegoke', 'orcid': 'https://orcid.org/0000-0002-9968-8014'}, 'institutions': [{'id': 'https://openalex.org/I26999989', 'display_name': 'University of the Free State', 'ror': 'https://ror.org/009xwd568', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26999989']}, {'id': 'https://openalex.org/I181631907', 'display_name': 'University of Ibadan', 'ror': 'https://ror.org/03wx2rr30', 'country_code': 'NG', 'type': 'education', 'lineage': ['https://openalex.org/I181631907']}], 'countries': ['NG', 'ZA'], 'is_corresponding': False, 'raw_author_name': 'Ayodeji Adegoke', 'raw_affiliation_strings': ['Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan 200005, Nigeria', 'Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I26999989']}, {'raw_affiliation_string': 'Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan 200005, Nigeria', 'institution_ids': ['https://openalex.org/I181631907']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5035439130', 'display_name': 'Samson S. Mashele', 'orcid': 'https://orcid.org/0000-0002-6339-4807'}, 'institutions': [{'id': 'https://openalex.org/I110603874', 'display_name': 'Central University of Technology', 'ror': 'https://ror.org/033z08192', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I110603874']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Samson Mashele', 'raw_affiliation_strings': ['Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, Central University of Technology, Bloemfontein 9300, South Africa', 'institution_ids': ['https://openalex.org/I110603874']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5082042907'], 'corresponding_institution_ids': ['https://openalex.org/I26999989'], 'apc_list': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 28.493, 'has_fulltext': False, 'cited_by_count': 342, 'citation_normalized_percentile': {'value': 0.999659, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '27', 'issue': '17', 'first_page': '5730', 'last_page': '5730'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10124', 'display_name': 'Prostate Cancer Diagnosis and Treatment', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12465', 'display_name': 'Cancer, Lipids, and Metabolism', 'score': 0.9839, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.9007238}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8259803}, {'id': 'https://openalex.org/C2779466945', 'wikidata': 'https://www.wikidata.org/wiki/Q1765251', 'display_name': 'Prostatectomy', 'level': 4, 'score': 0.7187238}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.57959956}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.5787272}, {'id': 'https://openalex.org/C2777899217', 'wikidata': 'https://www.wikidata.org/wiki/Q4759439', 'display_name': 'Androgen deprivation therapy', 'level': 4, 'score': 0.5248544}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.5203461}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.5037696}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.48975182}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.46744713}, {'id': 'https://openalex.org/C2776235491', 'wikidata': 'https://www.wikidata.org/wiki/Q9625', 'display_name': 'Prostate', 'level': 3, 'score': 0.43342027}], 'mesh': [{'descriptor_ui': 'D000726', 'descriptor_name': 'Androgen Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017430', 'descriptor_name': 'Prostate-Specific Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011468', 'descriptor_name': 'Prostatectomy', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules27175730', 'pdf_url': 'https://www.mdpi.com/1420-3049/27/17/5730/pdf?version=1662455892', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/48f0a6225d864f19bd20b1d515b44784', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457814', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36080493', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules27175730', 'pdf_url': 'https://www.mdpi.com/1420-3049/27/17/5730/pdf?version=1662455892', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.88}], 'grants': [{'funder': 'https://openalex.org/F4320320671', 'funder_display_name': 'National Research Foundation', 'award_id': '129891'}], 'datasets': [], 'versions': [], 'referenced_works_count': 200, 'referenced_works': ['https://openalex.org/W1002798955', 'https://openalex.org/W1066085235', 'https://openalex.org/W14767499', 'https://openalex.org/W1550555606', 'https://openalex.org/W1605551216', 'https://openalex.org/W172047440', 'https://openalex.org/W1842649350', 'https://openalex.org/W1891130507', 'https://openalex.org/W189198258', 'https://openalex.org/W1893562964', 'https://openalex.org/W1913797671', 'https://openalex.org/W1961726172', 'https://openalex.org/W1968302410', 'https://openalex.org/W1968973920', 'https://openalex.org/W1970626305', 'https://openalex.org/W1971261511', 'https://openalex.org/W1976956469', 'https://openalex.org/W1981412372', 'https://openalex.org/W1985525755', 'https://openalex.org/W1985607582', 'https://openalex.org/W1986799557', 'https://openalex.org/W1991643603', 'https://openalex.org/W1992624438', 'https://openalex.org/W1992768781', 'https://openalex.org/W1993331455', 'https://openalex.org/W1994069530', 'https://openalex.org/W1994527193', 'https://openalex.org/W1997793819', 'https://openalex.org/W1998238618', 'https://openalex.org/W2010054556', 'https://openalex.org/W2010427019', 'https://openalex.org/W2010502306', 'https://openalex.org/W2012390829', 'https://openalex.org/W2012901046', 'https://openalex.org/W2016249226', 'https://openalex.org/W2019053369', 'https://openalex.org/W2022812071', 'https://openalex.org/W2024089135', 'https://openalex.org/W2024386653', 'https://openalex.org/W2026707626', 'https://openalex.org/W2027443214', 'https://openalex.org/W2028137606', 'https://openalex.org/W2030536448', 'https://openalex.org/W2032884648', 'https://openalex.org/W2034024919', 'https://openalex.org/W2036161320', 'https://openalex.org/W2037341816', 'https://openalex.org/W2037385860', 'https://openalex.org/W2041937775', 'https://openalex.org/W2042538001', 'https://openalex.org/W2044020773', 'https://openalex.org/W2044780723', 'https://openalex.org/W2044835625', 'https://openalex.org/W2045232151', 'https://openalex.org/W2050591841', 'https://openalex.org/W2054660061', 'https://openalex.org/W2057709304', 'https://openalex.org/W2059724367', 'https://openalex.org/W2065142831', 'https://openalex.org/W2071194784', 'https://openalex.org/W2071681016', 'https://openalex.org/W2072312057', 'https://openalex.org/W2075628339', 'https://openalex.org/W2084168527', 'https://openalex.org/W2084919005', 'https://openalex.org/W2087428438', 'https://openalex.org/W2089388848', 'https://openalex.org/W2090157347', 'https://openalex.org/W2092075875', 'https://openalex.org/W2092268174', 'https://openalex.org/W2093979977', 'https://openalex.org/W2096260602', 'https://openalex.org/W2096795721', 'https://openalex.org/W2099053285', 'https://openalex.org/W2100323988', 'https://openalex.org/W2100957967', 'https://openalex.org/W2101825119', 'https://openalex.org/W2101910338', 'https://openalex.org/W2103827181', 'https://openalex.org/W2105964050', 'https://openalex.org/W2111055432', 'https://openalex.org/W2111970888', 'https://openalex.org/W2116987200', 'https://openalex.org/W2120484554', 'https://openalex.org/W2123230901', 'https://openalex.org/W2130502504', 'https://openalex.org/W2131988712', 'https://openalex.org/W2133540186', 'https://openalex.org/W2135959527', 'https://openalex.org/W2136311117', 'https://openalex.org/W2137333511', 'https://openalex.org/W2144045015', 'https://openalex.org/W2145903740', 'https://openalex.org/W2146629016', 'https://openalex.org/W2147256573', 'https://openalex.org/W2147478452', 'https://openalex.org/W2148036070', 'https://openalex.org/W2148416479', 'https://openalex.org/W2151860429', 'https://openalex.org/W2153056550', 'https://openalex.org/W2153595871', 'https://openalex.org/W2156923287', 'https://openalex.org/W2157114402', 'https://openalex.org/W2160475700', 'https://openalex.org/W2163069284', 'https://openalex.org/W2165330616', 'https://openalex.org/W2167771237', 'https://openalex.org/W2176372762', 'https://openalex.org/W2181283187', 'https://openalex.org/W2207293016', 'https://openalex.org/W2256034989', 'https://openalex.org/W2329357671', 'https://openalex.org/W2333950962', 'https://openalex.org/W2402584954', 'https://openalex.org/W2418959584', 'https://openalex.org/W2481479138', 'https://openalex.org/W2488203186', 'https://openalex.org/W2531179469', 'https://openalex.org/W2554843886', 'https://openalex.org/W2557617892', 'https://openalex.org/W2561215745', 'https://openalex.org/W2585769337', 'https://openalex.org/W2588930356', 'https://openalex.org/W2593363109', 'https://openalex.org/W2594645705', 'https://openalex.org/W2684717879', 'https://openalex.org/W2733906300', 'https://openalex.org/W2740784582', 'https://openalex.org/W2755414250', 'https://openalex.org/W2765777509', 'https://openalex.org/W2772110171', 'https://openalex.org/W2788783025', 'https://openalex.org/W2789313931', 'https://openalex.org/W2790065092', 'https://openalex.org/W2792922126', 'https://openalex.org/W2793905111', 'https://openalex.org/W2794685427', 'https://openalex.org/W2801804034', 'https://openalex.org/W2805482442', 'https://openalex.org/W2808578253', 'https://openalex.org/W2810151222', 'https://openalex.org/W2810296916', 'https://openalex.org/W2810603803', 'https://openalex.org/W2852498087', 'https://openalex.org/W2885115131', 'https://openalex.org/W2892069171', 'https://openalex.org/W2896002881', 'https://openalex.org/W2898034317', 'https://openalex.org/W2900161004', 'https://openalex.org/W2902597370', 'https://openalex.org/W2903362002', 'https://openalex.org/W2913805825', 'https://openalex.org/W2921250589', 'https://openalex.org/W2923460174', 'https://openalex.org/W2926723874', 'https://openalex.org/W2929595741', 'https://openalex.org/W2937107212', 'https://openalex.org/W2937483840', 'https://openalex.org/W2938910251', 'https://openalex.org/W2948680670', 'https://openalex.org/W2987785136', 'https://openalex.org/W2995214965', 'https://openalex.org/W3004803942', 'https://openalex.org/W3006071559', 'https://openalex.org/W3006377533', 'https://openalex.org/W3007455850', 'https://openalex.org/W3008672214', 'https://openalex.org/W3009897694', 'https://openalex.org/W3010021808', 'https://openalex.org/W3022091090', 'https://openalex.org/W3044296243', 'https://openalex.org/W3045753156', 'https://openalex.org/W3081020835', 'https://openalex.org/W3083627738', 'https://openalex.org/W3084029392', 'https://openalex.org/W3085293458', 'https://openalex.org/W3095702276', 'https://openalex.org/W3098190681', 'https://openalex.org/W3101741912', 'https://openalex.org/W3128646645', 'https://openalex.org/W3132409365', 'https://openalex.org/W3152073730', 'https://openalex.org/W3166933635', 'https://openalex.org/W3180822691', 'https://openalex.org/W3186302355', 'https://openalex.org/W3200419551', 'https://openalex.org/W3205480639', 'https://openalex.org/W3208545549', 'https://openalex.org/W3210005317', 'https://openalex.org/W3211497439', 'https://openalex.org/W3216371517', 'https://openalex.org/W4206632931', 'https://openalex.org/W4207077292', 'https://openalex.org/W4214529013', 'https://openalex.org/W4214632803', 'https://openalex.org/W4224278910', 'https://openalex.org/W4245382454', 'https://openalex.org/W4249192981', 'https://openalex.org/W4253965675', 'https://openalex.org/W82591098'], 'related_works': ['https://openalex.org/W4401322566', 'https://openalex.org/W4292811293', 'https://openalex.org/W4223420209', 'https://openalex.org/W4200552296', 'https://openalex.org/W2960491491', 'https://openalex.org/W2753537866', 'https://openalex.org/W2728894889', 'https://openalex.org/W2133840519', 'https://openalex.org/W2035098213', 'https://openalex.org/W2033949587'], 'abstract_inverted_index': {'Prostate': [0, 65], 'cancer': [1, 24, 66, 98, 114, 142], 'is': [2], 'one': [3], 'of': [4, 43, 49, 59, 91, 163, 168], 'the': [5, 47, 50, 55, 60, 86, 92, 161, 166, 184, 198], 'malignancies': [6], 'that': [7, 187], 'affects': [8], 'men': [9, 18], 'and': [10, 57, 62, 76, 89, 104, 122, 154, 170, 207], 'significantly': [11], 'contributes': [12], 'to': [13, 38, 54, 85, 144, 173, 182], 'increased': [14], 'mortality': [15], 'rates': [16], 'in': [17, 80, 201], 'globally.': [19], 'Patients': [20], 'affected': [21], 'with': [22, 26, 189], 'prostate': [23, 44, 77, 97, 113, 141, 175, 202], 'present': [25, 111], 'either': [27], 'a': [28, 40, 69], 'localized': [29, 96], 'or': [30, 110], 'advanced': [31], 'disease.': [32], 'In': [33, 193], 'this': [34, 194], 'review,': [35], 'we': [36, 196], 'aim': [37], 'provide': [39], 'holistic': [41], 'overview': [42], 'cancer,': [45, 176, 203], 'including': [46], 'diagnosis': [48], 'disease,': [51, 61], 'mutations': [52], 'leading': [53], 'onset': [56], 'progression': [58], 'treatment': [63, 126, 139, 157, 191, 205, 212], 'options.': [64, 192, 213], 'diagnoses': [67], 'include': [68], 'digital': [70], 'rectal': [71], 'examination,': [72], 'prostate-specific': [73], 'antigen': [74], 'analysis,': [75], 'biopsies.': [78], 'Mutations': [79], 'certain': [81], 'genes': [82, 199], 'are': [83, 128], 'linked': [84], 'onset,': [87], 'progression,': [88], 'metastasis': [90], 'cancer.': [93], 'Treatment': [94], 'for': [95], 'encompasses': [99], 'active': [100], 'surveillance,': [101], 'ablative': [102], 'radiotherapy,': [103, 121], 'radical': [105], 'prostatectomy.': [106], 'Men': [107], 'who': [108], 'relapse': [109], 'metastatic': [112], 'receive': [115], 'androgen': [116], 'deprivation': [117], 'therapy': [118, 172], '(ADT),': [119], 'salvage': [120], 'chemotherapy.': [123], 'Currently,': [124], 'available': [125, 138, 204], 'options': [127], 'more': [129], 'effective': [130], 'when': [131], 'used': [132], 'as': [133, 160, 179, 181], 'combination': [134], 'therapy;': [135], 'however,': [136], 'despite': [137], 'options,': [140, 206], 'remains': [143], 'be': [145], 'incurable.': [146], 'There': [147], 'has': [148], 'been': [149], 'ongoing': [150], 'research': [151, 209], 'on': [152, 210], 'finding': [153], 'identifying': [155], 'other': [156], 'approaches': [158], 'such': [159], 'use': [162], 'traditional': [164], 'medicine,': [165], 'application': [167], 'nanotechnologies,': [169], 'gene': [171], 'combat': [174], 'drug': [177], 'resistance,': [178], 'well': [180], 'reduce': [183], 'adverse': [185], 'effects': [186], 'come': [188], 'current': [190, 208], 'article,': [195], 'summarize': [197], 'involved': [200], 'alternative': [211]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4295080856', 'counts_by_year': [{'year': 2024, 'cited_by_count': 225}, {'year': 2023, 'cited_by_count': 103}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-12-18T19:46:17.829517', 'created_date': '2022-09-10'}