Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4293223457', 'doi': 'https://doi.org/10.3390/encyclopedia2030105', 'title': 'Oxidative Stress in Relation to Aging and Exercise', 'display_name': 'Oxidative Stress in Relation to Aging and Exercise', 'publication_year': 2022, 'publication_date': '2022-08-25', 'ids': {'openalex': 'https://openalex.org/W4293223457', 'doi': 'https://doi.org/10.3390/encyclopedia2030105'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/encyclopedia2030105', 'pdf_url': 'https://www.mdpi.com/2673-8392/2/3/105/pdf?version=1661399876', 'source': {'id': 'https://openalex.org/S4210204877', 'display_name': 'Encyclopedia', 'issn_l': '2673-8392', 'issn': ['2673-8392'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2673-8392/2/3/105/pdf?version=1661399876', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5083197871', 'display_name': 'Dimphna Verhaegen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149079', 'display_name': 'Thomas More Kempen', 'ror': 'https://ror.org/04e7kpf57', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I4210149079']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Dimphna Verhaegen', 'raw_affiliation_strings': ['Biochemistry Department, Thomas More Kempen, Thomas More University, Kleinhoefstraat 4, 2440 Geel, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Biochemistry Department, Thomas More Kempen, Thomas More University, Kleinhoefstraat 4, 2440 Geel, Belgium', 'institution_ids': ['https://openalex.org/I4210149079']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069448939', 'display_name': 'Kelly Smits', 'orcid': 'https://orcid.org/0000-0001-8686-4173'}, 'institutions': [{'id': 'https://openalex.org/I4210149079', 'display_name': 'Thomas More Kempen', 'ror': 'https://ror.org/04e7kpf57', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I4210149079']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Kelly Smits', 'raw_affiliation_strings': ['Biochemistry Department, Thomas More Kempen, Thomas More University, Kleinhoefstraat 4, 2440 Geel, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Biochemistry Department, Thomas More Kempen, Thomas More University, Kleinhoefstraat 4, 2440 Geel, Belgium', 'institution_ids': ['https://openalex.org/I4210149079']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046711289', 'display_name': 'Nádia Osório', 'orcid': 'https://orcid.org/0000-0001-9559-2165'}, 'institutions': [{'id': 'https://openalex.org/I4210102980', 'display_name': 'Escola Superior de Tecnologia da Saúde de Coimbra', 'ror': 'https://ror.org/018j3hx85', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I4210102980']}, {'id': 'https://openalex.org/I293362453', 'display_name': 'Polytechnic Institute of Coimbra', 'ror': 'https://ror.org/01n8x4993', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I293362453']}, {'id': 'https://openalex.org/I76903346', 'display_name': 'University of Coimbra', 'ror': 'https://ror.org/04z8k9a98', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I76903346']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Nádia Osório', 'raw_affiliation_strings': ['Ciências Biomédicas Laboratoriais, Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'Laboratório de Investigação em Ciências Aplicadas à Saúde (LABINSAÚDE), Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Instituto Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'Unidade I&D Química-Física Molecular, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Ciências Biomédicas Laboratoriais, Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I4210102980']}, {'raw_affiliation_string': 'Laboratório de Investigação em Ciências Aplicadas à Saúde (LABINSAÚDE), Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Instituto Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I4210102980', 'https://openalex.org/I293362453']}, {'raw_affiliation_string': 'Unidade I&D Química-Física Molecular, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I76903346']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047595312', 'display_name': 'Armando Caseiro', 'orcid': 'https://orcid.org/0000-0001-7844-0506'}, 'institutions': [{'id': 'https://openalex.org/I4210102980', 'display_name': 'Escola Superior de Tecnologia da Saúde de Coimbra', 'ror': 'https://ror.org/018j3hx85', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I4210102980']}, {'id': 'https://openalex.org/I293362453', 'display_name': 'Polytechnic Institute of Coimbra', 'ror': 'https://ror.org/01n8x4993', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I293362453']}, {'id': 'https://openalex.org/I76903346', 'display_name': 'University of Coimbra', 'ror': 'https://ror.org/04z8k9a98', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I76903346']}], 'countries': ['PT'], 'is_corresponding': True, 'raw_author_name': 'Armando Caseiro', 'raw_affiliation_strings': ['Ciências Biomédicas Laboratoriais, Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'Laboratório de Investigação em Ciências Aplicadas à Saúde (LABINSAÚDE), Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Instituto Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'Unidade I&D Química-Física Molecular, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Ciências Biomédicas Laboratoriais, Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I4210102980']}, {'raw_affiliation_string': 'Laboratório de Investigação em Ciências Aplicadas à Saúde (LABINSAÚDE), Escola Superior de Tecnologia da Saúde de Coimbra (ESTeSC), Instituto Politécnico de Coimbra, Rua 5 de Outubro, 3046-854 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I4210102980', 'https://openalex.org/I293362453']}, {'raw_affiliation_string': 'Unidade I&D Química-Física Molecular, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal', 'institution_ids': ['https://openalex.org/I76903346']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5047595312'], 'corresponding_institution_ids': ['https://openalex.org/I4210102980', 'https://openalex.org/I293362453', 'https://openalex.org/I76903346'], 'apc_list': {'value': 1000, 'currency': 'CHF', 'value_usd': 1082, 'provenance': 'doaj'}, 'apc_paid': {'value': 1000, 'currency': 'CHF', 'value_usd': 1082, 'provenance': 'doaj'}, 'fwci': 2.042, 'has_fulltext': False, 'cited_by_count': 13, 'citation_normalized_percentile': {'value': 0.680759, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '2', 'issue': '3', 'first_page': '1545', 'last_page': '1558'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11585', 'display_name': 'Exercise and Physiological Responses', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11585', 'display_name': 'Exercise and Physiological Responses', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12554', 'display_name': 'Vitamin C and Antioxidants Research', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13012', 'display_name': 'Coenzyme Q10 studies and effects', 'score': 0.9914, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.9612661}, {'id': 'https://openalex.org/C48349386', 'wikidata': 'https://www.wikidata.org/wiki/Q424361', 'display_name': 'Reactive oxygen species', 'level': 2, 'score': 0.76957744}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.74042684}, {'id': 'https://openalex.org/C57600042', 'wikidata': 'https://www.wikidata.org/wiki/Q227564', 'display_name': 'Oxidative phosphorylation', 'level': 2, 'score': 0.610765}, {'id': 'https://openalex.org/C2776759703', 'wikidata': 'https://www.wikidata.org/wiki/Q1066907', 'display_name': 'Longevity', 'level': 2, 'score': 0.48127383}, {'id': 'https://openalex.org/C3020296196', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative damage', 'level': 3, 'score': 0.44595954}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.39201197}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.3688667}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3253225}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.31368685}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.31331635}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29665625}, {'id': 'https://openalex.org/C74909509', 'wikidata': 'https://www.wikidata.org/wiki/Q10387', 'display_name': 'Gerontology', 'level': 1, 'score': 0.16353372}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/encyclopedia2030105', 'pdf_url': 'https://www.mdpi.com/2673-8392/2/3/105/pdf?version=1661399876', 'source': {'id': 'https://openalex.org/S4210204877', 'display_name': 'Encyclopedia', 'issn_l': '2673-8392', 'issn': ['2673-8392'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/85e1119ade454376af74e67d4da52aa9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10400.26/44676', 'pdf_url': 'https://comum.rcaap.pt/bitstream/10400.26/44676/1/Oxidative%20stress%20in%20relation%20to%20aging%20and%20exercise.pdf', 'source': {'id': 'https://openalex.org/S4306401667', 'display_name': 'Repositório Comum (Repositório Científico de Acesso Aberto de Portugal)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/encyclopedia2030105', 'pdf_url': 'https://www.mdpi.com/2673-8392/2/3/105/pdf?version=1661399876', 'source': {'id': 'https://openalex.org/S4210204877', 'display_name': 'Encyclopedia', 'issn_l': '2673-8392', 'issn': ['2673-8392'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.74, 'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W1515106017', 'https://openalex.org/W1865433224', 'https://openalex.org/W1867810224', 'https://openalex.org/W1965098193', 'https://openalex.org/W1971136149', 'https://openalex.org/W1976346227', 'https://openalex.org/W1976950210', 'https://openalex.org/W1982647833', 'https://openalex.org/W2006330191', 'https://openalex.org/W2012080584', 'https://openalex.org/W2017118225', 'https://openalex.org/W2023677185', 'https://openalex.org/W2026261400', 'https://openalex.org/W2037844862', 'https://openalex.org/W2038500838', 'https://openalex.org/W2055199581', 'https://openalex.org/W2059410642', 'https://openalex.org/W2065086108', 'https://openalex.org/W2090379727', 'https://openalex.org/W2091482618', 'https://openalex.org/W2094595997', 'https://openalex.org/W2110689286', 'https://openalex.org/W2126525177', 'https://openalex.org/W2132878122', 'https://openalex.org/W2134980892', 'https://openalex.org/W2147205664', 'https://openalex.org/W2163208521', 'https://openalex.org/W2170463117', 'https://openalex.org/W2255649368', 'https://openalex.org/W2331190475', 'https://openalex.org/W2392975937', 'https://openalex.org/W2408806034', 'https://openalex.org/W2523739397', 'https://openalex.org/W2732112239', 'https://openalex.org/W2736054471', 'https://openalex.org/W2794642028', 'https://openalex.org/W2913032783', 'https://openalex.org/W2916458129', 'https://openalex.org/W2996519594', 'https://openalex.org/W3002676463', 'https://openalex.org/W3014023943', 'https://openalex.org/W3022014008', 'https://openalex.org/W3037885010', 'https://openalex.org/W3041799277', 'https://openalex.org/W3129027105', 'https://openalex.org/W3131860927', 'https://openalex.org/W3134719402', 'https://openalex.org/W3136672980', 'https://openalex.org/W3193736912', 'https://openalex.org/W4206843434'], 'related_works': ['https://openalex.org/W99063305', 'https://openalex.org/W4387741623', 'https://openalex.org/W4367053317', 'https://openalex.org/W3157404951', 'https://openalex.org/W3091876869', 'https://openalex.org/W3031685627', 'https://openalex.org/W2300525609', 'https://openalex.org/W2241760478', 'https://openalex.org/W1604182531', 'https://openalex.org/W1584220612'], 'abstract_inverted_index': {'Oxidative': [0, 26], 'stress': [1, 27, 70, 99, 117], 'is': [2, 28, 85], 'an': [3], 'imbalance': [4], 'between': [5], 'oxidants': [6], 'and': [7, 20, 22, 42, 82, 96, 122, 157], 'antioxidants': [8], 'in': [9, 15, 59, 71, 90, 101, 134, 144], 'favor': [10], 'of': [11, 17, 33, 93, 129], 'the': [12, 72, 91, 97, 131, 135], 'oxidants,': [13], 'resulting': [14], 'disruption': [16], 'redox': [18], 'signaling': [19], 'control': [21], 'causing': [23], 'molecular': [24], 'damage.': [25], 'related': [29], 'to': [30, 67, 109, 114], 'a': [31, 60, 111, 140], 'variety': [32], 'diseases,': [34, 38, 40], 'for': [35], 'example,': [36, 78], 'cardiovascular': [37], 'neurodegenerative': [39], 'infections,': [41], 'cancer.': [43], 'It': [44], 'might': [45], 'be': [46, 110, 139], 'that': [47, 153], 'oxidative': [48, 69, 98, 116, 155], 'stress,': [49], 'and,': [50], 'more': [51], 'specifically,': [52], 'reactive': [53], 'oxygen': [54], 'species': [55], '(ROS),': [56], 'affects': [57], 'longevity': [58], 'subtle': [61], 'way': [62, 113], 'through': [63], 'signaling.': [64], 'Possible': [65], 'therapies': [66, 147], 'reduce': [68, 115], 'elderly': [73, 136], 'are': [74], 'nutritional': [75], 'intervention': [76], '(for': [77], 'caloric': [79], 'restriction': [80], '(CR))': [81], 'exercise.': [83], 'Exercise': [84], 'associated': [86], 'with': [87, 105, 160], 'favorable': [88], 'changes': [89], 'expression': [92], 'antioxidant': [94, 124, 132], 'enzymes': [95], 'status': [100], 'general.': [102], 'A': [103, 126], 'diet': [104], 'CR': [106], 'also': [107], 'seems': [108], 'promising': [112], 'by': [118], 'decreasing': [119], 'oxidant': [120], 'emission': [121], 'improving': [123], 'mechanisms.': [125], 'better': [127], 'understanding': [128], 'where': [130], 'mechanisms': [133], 'fail': [137], 'could': [138], 'big': [141], 'step': [142], 'forward': [143], 'developing': [145], 'new': [146], '(such': [148], 'as': [149], 'exercise': [150], 'or': [151], 'diet)': [152], 'prevent': [154], 'damage': [156], 'cellular': [158], 'dysfunction': [159], 'age.': [161]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4293223457', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 5}], 'updated_date': '2024-12-08T14:33:19.047471', 'created_date': '2022-08-27'}