Title: Complications of Basivertebral Nerve Ablation
Abstract: Chapter 37 Complications of Basivertebral Nerve Ablation Ameer Ali DO, Ameer Ali DOSearch for more papers by this authorMelissa Lau MD, Melissa Lau MDSearch for more papers by this authorMichael DePalma MD, Michael DePalma MDSearch for more papers by this authorDouglas Beall MD, Douglas Beall MDSearch for more papers by this author Ameer Ali DO, Ameer Ali DOSearch for more papers by this authorMelissa Lau MD, Melissa Lau MDSearch for more papers by this authorMichael DePalma MD, Michael DePalma MDSearch for more papers by this authorDouglas Beall MD, Douglas Beall MDSearch for more papers by this author Book Editor(s):Serdar Erdine MD, FIPP, Serdar Erdine MD, FIPP Professor Emeritus, Department of Algology, Medical Faculty of Istanbul University, Istanbul Pain Center, Past President of European Pain Federation, Past President of World Institute of Pain, Istanbul, TurkeySearch for more papers by this authorPeter S. Staats MD, MBA, APIPP, FIPP, Peter S. Staats MD, MBA, APIPP, FIPP Chief Medical Officer, National Spine and Pain Centers, Past President of World Institute of Pain, Atlantic Beach, USA Chief Medical Officer, President, World Institute of Pain, Washington DC, USASearch for more papers by this author First published: 04 August 2022 https://doi.org/10.1002/9781119757306.ch37 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Abstract The cartilaginous end plates (CEPs) are densely innervated by the basivertebral nerve (BVN) and its branches, which have been found to contain substance P, a neurotransmitter of the tachykinin family associated with the transmission of pain. By targeting the BVN, intraosseous basivertebral nerve ablation (BVNA) can disrupt the neurotransmission of pain and thereby reduce pain originating from the vertebral CEPs also called vertebrogenic pain. This chapter includes discussions of the anatomy of BVN, indications for BVNA, technical approaches with pictures, potential complications, and strategies for preventing complications. Factors that can contribute to procedural complications include poor visualization of the anatomy, operator error, inadequate patient monitoring or improper aseptic technique. Generally, operator error is due to an unfamiliarity with either the equipment, a lack of knowledge of radiographic spinal anatomy or poor fluoroscopic visual-spatial skills. The BVNA results cannot be generalized to the entire patient population with chronic low back pain. References Rao , D. , Scuderi , G. , Scuderi , C. et al. ( 2018 ). The use of imaging in management of patients with low back pain . Journal of Clinical Imaging Science 8 : 30 . Weishaupt , D. , Zanetti , M. , Hodler , J. et al. ( 2001 ). Painful lumbar disc derangement: relevance of endplate abnormalities at MR imaging . Radiology 218 ( 2 ): 420 – 427 . Brown , M.F. , Hukkanen , M.V. , McCarthy , I.D. et al. ( 1997 ). Sensory and sympathetic innervation of the vertebral endplate in patients with degenerative disc disease . The Journal of Bone and Joint Surgery. British Volume 79 ( 1 ): 147 – 153 . Fischgrund , J.S. , Rhyne , A. , Franke , J. et al. ( 2018 ). Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham controlled multi-center study . European Spine Journal 27 ( 5 ): 1146 – 1156 . Fischgrund , J.S. , Rhyne , A. , Macadaeg , K. et al. ( 2020 ). Long-term outcomes following intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: 5-year treatment arm results from a prospective randomized double-blind sham-controlled multi-center study . European Spine Journal 29 : 1925 – 1934 . DePalma , M.J. , Ketchum , J.M. , and Saullo , T. ( 2011 ). What is the source of chronic low back pain and does age play a role? Pain Medicine 12 : 224 – 233 . Lotz , J.C. , Fields , A.J. , and Liebenberg , E.C. ( 2013 ). The role of the vertebral end plate in low back pain . Global Spine Journal 3 ( 3 ): 153 – 164 . Xu , L. , Chu , B. , Feng , Y. et al. ( 2016 ). Modic changes in lumbar spine: prevalence and distribution patterns of end plate edema and end plate sclerosis . The British Journal of Radiology 89 : 20150650 . Zehra , U. , Cheung , J.P.Y. , Bow , C. et al. ( 2019 ). Multidimensional vertebral endplate defects are associated with disc degeneration, Modic changes, facet joint abnormalities, and pain . Journal of Orthopaedic Research 37 : 1080 – 1089 . Antonacci , M.D. , Mody , D.R. , and Heggeness , M.H. ( 1998 ). Innervation of the human vertebral body: a histologic study . Journal of Spinal Disorders 11 ( 6 ): 526 – 531 . May , S. and Donelson , R. ( 2011 ). Mechanical assessment of axial lumbosacral pain . In: iSpine Evidence-Based Interventional Spine Care (ed. M.J. DePalma ), 26 – 35 . New York : Demos . Courtesy of Dr. Douglass Beall . Joe , E. , Lee , J.W. , Park , K.W. et al. ( 2014 ). Herniation of cartilaginous endplates in the lumbar spine: MRI findings . American Journal of Roentgenology 204 : 1075 – 1081 . Fischgrund , J.S. ( 2019 ). Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain . International Journal of Spine Surgery 2019 13 ( 2 ): 1 – 10 . Dudli , S. , Fields , A.J. , Samartzis , D. et al. ( 2016 ). Pathobiology of Modic changes . European Spine Journal 25 ( 11 ): 3723 – 2734 . Truumees , E. , Macadaeg , K. , Pena , E. et al. ( 2019 ). A prospective, open-label, single-arm, multi-center study of intraosseous basivertebral nerve ablation for the treatment of chronic low back pain . European Spine Journal 28 ( 7 ): 1594 – 1602 . Khalil , J.G. , Smuck , M. , Koreckij , T. et al. ( 2019 ). A prospective, randomized, multicenter study of intraosseous basivertebral nerve ablation for the treatment of chronic low back pain . Spine Journal 19 ( 10 ): 1620 – 1632 . Courtesy of Dr. Douglass Beall . Cheng , J. and Abdi , S. ( 2007 ). Complications of joint, tendon, and muscle injections . Techniques in Regional Anesthesia & Pain Management 11 : 141 – 147 . Gupa , A. and Cohen , S.P. ( 2011 ). Neuroablative techniques for sacroiliac pain . In: iSpine Evidence-Based Interventional Spine Care (ed. M.J. DePalma ), 136 – 146 . New York : Demos . Courtesy of Dr. Douglass Beall. Complications of Pain‐Relieving Procedures: An Illustrated Guide ReferencesRelatedInformation
Publication Year: 2022
Publication Date: 2022-08-04
Language: en
Type: other
Indexed In: ['crossref']
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